scholarly journals Risk Factors for Asymptomatic and Symptomatic Intracranial Atherosclerosis Determined by Magnetic Resonance Vessel Wall Imaging in Chinese Population: A Case–Control Study

2022 ◽  
Vol Volume 18 ◽  
pp. 61-70
Author(s):  
Yongjun Han ◽  
Runhua Zhang ◽  
Dandan Yang ◽  
Dongye Li ◽  
Hualu Han ◽  
...  
Keyword(s):  
Risk Factors ◽  
Magnetic Resonance ◽  
Chinese Population ◽  
Vessel Wall ◽  
Case Control Study ◽  
Case Control ◽  
Vessel Wall Imaging ◽  
Intracranial Atherosclerosis ◽  
Control Study ◽  
Wall Imaging

Risk factors associated with TB, a case-control study in a Chinese population

2017 ◽  
Vol 1 ◽  
pp. 58-58
Author(s):  
Cheng Chen ◽  
Limei Zhu ◽  
Dandan Yang ◽  
Yan Shao ◽  
Honghuan Song ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chinese Population ◽  
Case Control Study ◽  
Case Control ◽  
Factors Associated ◽  
Control Study

scholarly journals Associations of TGFBR1 and TGFBR2 gene polymorphisms with the risk of hypospadias: a case–control study in a Chinese population

2017 ◽  
Vol 37 (5) ◽  
Author(s):  
Xin-Rui Han ◽  
Xin Wen ◽  
Shan Wang ◽  
Xiao-Wu Hong ◽  
Shao-Hua Fan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gene Polymorphisms ◽  
Chinese Population ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Abnormal Pregnancy ◽  
Control Study ◽  
Genotype And Allele Frequencies

This case–control study investigated the association of transforming growth factor-β (TGF-β) receptor type I and II (TGFBR1 and TGFBR2) gene polymorphisms with the risk of hypospadias in a Chinese population. One hundred and sixty two patients suffering from hypospadias were enrolled as case group and 165 children who underwent circumcision were recruited as control group. Single nucleotide polymorphisms (SNPs) in TGFBR1 and TGFBR2 genes were selected on the basis of genetic data obtained from HapMap. PCR-restriction fragment length polymorphism (PCR-RFLP) was performed to identify TGFBR1 and TGFBR2 gene polymorphisms and analyze genotype distribution and allele frequency. Logistic regression analysis was conducted to estimate the risk factors for hypospadias. No significant difference was found concerning the genotype and allele frequencies of TGFBR1 rs4743325 polymorphism between the case and control groups. However, genotype and allele frequencies of TGFBR2 rs6785358 in the case group were significantly different in contrast with those in the control group. Patients carrying the G allele of TGFBR2 rs6785358 polymorphism exhibited a higher risk of hypospadias compared with the patients carrying the A allele (P<0.05). The TGFBR2 rs6785358 genotype was found to be significantly related to abnormal pregnancy and preterm birth (both P<0.05). The frequency of TGFBR2 rs6785358 GG genotype exhibited significant differences amongst patients suffering from four different pathological types of hypospadias. Logistic regression analysis revealed that preterm birth, abnormal pregnancy, and TGFBR2 rs6785358 were the independent risk factors for hypospadias. Our study provides evidence that TGFBR2 rs6785358 polymorphism might be associated with the risk of hypospadias.

Risk factors for esophageal adenocarcinoma: A case-control study

2001 ◽  
Vol 120 (5) ◽  
pp. A442-A442
Author(s):  
B AVIDAN ◽  
A SONNENBERG ◽  
T SCHNELL ◽  
G CHEJFEC ◽  
A METZ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Adenocarcinoma ◽  
Case Control Study ◽  
Case Control ◽  
Control Study
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