scholarly journals Advanced spatial analytics and management: models, methods and applications

2016 ◽  
Vol 14 (2) ◽  
pp. 67-73
Author(s):  
Sven Müller

In this contribution, a concept of the integration of spatial predictive analytics and mathematical programs for spatial decision making – namely, advanced spatial analytics and management – is outlined. In particular, selected methods for spatial predictive analytics are discussed, including spatial econometrics and discrete choice analysis. Then, the integration of spatial predictive models in mathematical programs (prescriptive analytics) for facility location and districting is demonstrated. The paper includes illustrative applications which stem from health care, retail, marketing, logistics, and transportation. Based on the discussion, future research perspectives are developed

2021 ◽  
Vol 167 ◽  
pp. 112313
Author(s):  
Zhaoyang Yang ◽  
Zhi Chen ◽  
Kenneth Lee ◽  
Edward Owens ◽  
Michel C. Boufadel ◽  
...  

2021 ◽  
Vol 22 (7) ◽  
pp. 3571
Author(s):  
Bonglee Kim ◽  
Ji-Eon Park ◽  
Eunji Im ◽  
Yongmin Cho ◽  
Jinjoo Lee ◽  
...  

Biocompatible nanoparticles (NPs) containing polymers, lipids (liposomes and micelles), dendrimers, ferritin, carbon nanotubes, quantum dots, ceramic, magnetic materials, and gold/silver have contributed to imaging diagnosis and targeted cancer therapy. However, only some NP drugs, including Doxil® (liposome-encapsulated doxorubicin), Abraxane® (albumin-bound paclitaxel), and Oncaspar® (PEG-Asparaginase), have emerged on the pharmaceutical market to date. By contrast, several phytochemicals that were found to be effective in cultured cancer cells and animal studies have not shown significant efficacy in humans due to poor bioavailability and absorption, rapid clearance, resistance, and toxicity. Research to overcome these drawbacks by using phytochemical NPs remains in the early stages of clinical translation. Thus, in the current review, we discuss the progress in nanotechnology, research milestones, the molecular mechanisms of phytochemicals encapsulated in NPs, and clinical implications. Several challenges that must be overcome and future research perspectives are also described.


2021 ◽  
Vol 13 (13) ◽  
pp. 7010
Author(s):  
Lorenzo Franchi ◽  
Thierry Vanelslander

For centuries, ports have functioned as an economic engine, facilitating maritime transport, offering prosperity and social development to the host communities. Ports are gateways for international trade playing a vital role in the world economy, but it is not excluded that port operations can also have adverse effects on the environment. Air and water emissions, marine sediments, noise, waste generation, loss and degradation of terrestrial habitats and changes to marine ecosystems are just some of the leading environmental challenges with port’s operations. Environmental management within port operations has been a rapidly growing trend, with many ports around the world adopting different types of approaches and initiatives to improve ecological performance. Despite that many ports around the world have implemented greening strategies for growth and sustainable development, there are still many other ports that work less than they should do on environmental aspects and on the generation of ‘green ports’. These latter have fallen behind in the development of the theme. Therefore, the work reported here aims at analyzing what the best way to act should be, even starting from the beginning for a port that is not very innovative, in order to pursue the practical and theoretical levels of ‘green port’.


Parasite ◽  
2020 ◽  
Vol 27 ◽  
pp. 49 ◽  
Author(s):  
André G. Buret ◽  
Simone M. Cacciò ◽  
Loïc Favennec ◽  
Staffan Svärd

Although Giardia duodenalis is recognized as one of the leading causes of parasitic human diarrhea in the world, knowledge of the mechanisms of infection is limited, as the pathophysiological consequences of infection remain incompletely elucidated. Similarly, the reason for and consequences of the very specific genome-organization in this parasite with 2 active nuclei is only partially known. Consistent with its tradition, the 7th International Giardia and Cryptosporidium Conference (IGCC 2019) was held from June 23 to 26, 2019, at the Faculty of Medicine and Pharmacy of the University of Rouen-Normandie, France, to discuss current research perspectives in the field. This renowned event brought together an international delegation of researchers to present and debate recent advances and identify the main research themes and knowledge gaps. The program for this interdisciplinary conference included all aspects of host-parasite relationships, from basic research to applications in human and veterinary medicine, as well as the environmental issues raised by water-borne parasites and their epidemiological consequences. With regard to Giardia and giardiasis, the main areas of research for which new findings and the most impressive communications were presented and discussed included: parasite ecology and epidemiology of giardiasis, Giardia-host interactions, and cell biology of Giardia, genomes and genomic evolution. The high-quality presentations discussed at the Conference noted breakthroughs and identified new opportunities that will inspire researchers and funding agencies to stimulate future research in a “one health” approach to improve basic knowledge and clinical and public health management of zoonotic giardiasis.


2014 ◽  
Vol 24 (3) ◽  
pp. 219-227 ◽  
Author(s):  
Francisco J Tarazona-Santabalbina ◽  
Juan R Doménech-Pascual ◽  
Ángel Belenguer-Varea A ◽  
Eduardo Rovira Daudi

SummaryHip fracture is very common among older patients, who are characterized by increased co-morbidities, including cognitive impairment. These patients have an increased risk of falls and fractures, poorer functional recovery and lower survival both in hospital and 12 months after discharge. We review the survival and functional outcomes of older patients with cognitive impairment and hip fracture managed in orthogeriatric units, and highlight the gaps in our knowledge of the efficacy and efficiency of specific orthogeriatric programmes for such patients and the future research perspectives in this field.


2016 ◽  
Vol 6 (1) ◽  
pp. 45
Author(s):  
Florian Vincent Haase ◽  
Maria Kohlmeyer ◽  
Beatrice Rich ◽  
Ralf Woll

<p>Previous studies examined additional willingness to pay for socially responsible primary goods. However, technical products have not been considered. Therefore, the purpose of this study is to estimate additional willingness to pay for socially responsible technical products. Within an overview of given methods for measuring willingness to pay, the discrete choice analysis was applied to this study. As technical products, computer mice were chosen exemplary, since there is a partially fair mouse available. It was found that two of three fair labeled mice have a negative willingness to pay. Only consumers of the fair produced and labeled mouse has a positive willingness to pay. The consumers pay perhaps more attention to the aspect of social responsibility, if presented brands are comparatively unknown. In this connection, consumers allocate a higher value to social responsibility.</p>


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