scholarly journals Clinical experience with the use of the intestinal antibiotic Rifaximin for celiac disease

2019 ◽  
pp. 94-98
Author(s):  
L. S. Оrеshkо ◽  
E. A. Semenova
Keyword(s):  
Celiac Disease ◽  
Intestinal Microflora ◽  
Medical Science ◽  
Elimination Diet ◽  
Quantitative Composition ◽  
Antibacterial Drugs ◽  
Strict Adherence ◽  
Qualitative And Quantitative ◽  
High Antibacterial Activity ◽  
Kinetic Activity

The article is devoted to new possibilities in the treatment of hereditary intestinal diseases, accompanied by a decrease in kinetic activity or the absence of enteric enzymes, including celiac disease. Despite strict adherence to the elimination diet, some patients develop IBS-like symptoms, which may be caused by a violation of the qualitative and quantitative composition of the intestinal microflora. Dysbiotic disorders play a role in the pathogenesis of the appearance of IBS-like symptoms and complicate the course of celiac disease, which requires the use of antibacterial drugs. The presence of side effects when using systemic antibacterial drugs limits their use. In this regard, the search for ways to correct the intestinal microflora, as well as the study of various approaches to maintaining the intestinal microecology in a state of physiological equilibrium in patients with celiac disease, are relevant for medical science. The article presents a clinical example of the successful and safe use of a drug with low absorption, high antibacterial activity – rifaximin in a patient with celiac disease to correct dysbiotic disorders.

scholarly journals THE COMPLEX METHOD FOR DETERMINATION OF INTESTINAL MICROFLORA COMPOSITION OF LABORATORY ANIMALS

2015 ◽  
Vol 22 ◽  
pp. 60-65
Author(s):  
M. V. Kaminska
Keyword(s):  
Intestinal Microflora ◽  
Laboratory Animals ◽  
Albino Rats ◽  
Quantitative Composition ◽  
Complex Method ◽  
Qualitative And Quantitative ◽  
Method Of Determination ◽  
Full Picture

The method of determination of qualitative and quantitative composition of intestinal microflora of laboratory animals, namely albino rats, was described. The method allows to simultaneously identify different groups of microorganisms in one sample of intestinal composition and to get a full picture of microbocoenosis within 4 days that allows to consider animal’s health, dysbiotic infringement in intestinal microflora composition and its correction with probiotic preparations.

scholarly journals Effect of therapeutic and prophylactic complex DLK (Dironet, Lactobifadol, Forage Keratin) on the intestinal microbiocenosis of the Blue Frost fox at toxascariosis

2021 ◽  
Vol 15 (4) ◽  
pp. 91-99
Author(s):  
A. P. Konovalov ◽  
I. I. Tsepilova ◽  
F. I. Vasilevich ◽  
S. Y. Pigina
Keyword(s):  
Intestinal Microflora ◽  
Quantitative Composition ◽  
Pathogenic Microorganisms ◽  
Experimental Animals ◽  
Qualitative And Quantitative ◽  
Breeding Herd ◽  
Lactic Bacteria ◽  
Toxascaris Leonina ◽  
Intestinal Microbiocenosis

The purpose of the research is determining the effect of the therapeutic and prophylactic complex of Dironet, Lactobifadol and fodder Keratin (DLK) on the qualitative and quantitative composition of the intestinal microflora affected by toxascariosis in the Blue Frost fox.Materials and methods. The research was carried out on the Fur Breeding Farm “Vyatka”, Slobodskoy District, the Kirov Region. The study objects were 24 female Blue Frost foxes culled from the breeding herd. To determine the quality of the skins obtained from the experimental animals, we sorted flint-dried skins.Results and discussion. After the introduction of the therapeutic and preventive complex DLK into the diet of sick animals, the positive dynamics was observed in the quantitative and qualitative composition of intestinal microorganisms. In animals of the experimental groups that were administered DLK, the number of bifidus bacteria, lactic bacteria and fecal enterococci increased; there was a significant decrease or complete absence of pathogenic and conditionally pathogenic microorganisms, fusobacteria, streptococci, clostridia, typical lactose-negative and hemolytic Escherichia, aureus and saprophytic staphylococcus, common Proteus and fungi of the Candida genus. In animals infected by Toxascaris leonina that did not receive the complex therapy, a decrease in lactic acid bacteria and an increase in the content of pathogenic and commensal microorganisms were noted. Under the output of the fur production, the infected animals showed the lowest percentage of skins in terms of quality of 7.16%, which was 0.38% less in comparison with healthy foxes, and 0.51% less in comparison with treated Blue Frost foxes.

scholarly journals Intestinal microbiocenosis in the obese patients with osteoarthritis

2012 ◽  
Vol 58 (3) ◽  
pp. 12-15
Author(s):  
M Iu Gul'neva ◽  
S M Noskov ◽  
É V Malafeeva
Keyword(s):  
Intestinal Microflora ◽  
Therapeutic Strategy ◽  
Coliform Bacteria ◽  
Quantitative Composition ◽  
Obese Patients ◽  
Qualitative And Quantitative Analysis ◽  
Qualitative And Quantitative ◽  
Body Weights ◽  
Bacteriological Method ◽  
Intestinal Microbiocenosis

Specific features of colonic microbiocenosis were investigated in 64 patients presenting with osteoarthritis. They were divided into 4 groups including patients with the normal body weights and those with grade I, II, and III obesity respectively. The qualitative and quantitative analysis of intestinal microflora was performed by the bacteriological method. It was shown that obesity was associated with an increased frequency of isolation of enterococci despite their decreased content. Simultaneously, variations in the diversity of opportunistic microorganisms were documented. Alterations in the qualitative and quantitative composition of intestinal microbiocenosis in the patients with osteoarthrosis depended on the degree of obesity. Grade III obesity was associated with the most pronounced decrease in the occurrence of bacteroids, entercococci, and lactose-positive coliform bacteria. It is concluded that the development of dysbiosis in the large intestine should be taken into consideration in the choice of combined therapeutic strategy for the treatment of the patients with osteoarthritis and concomitant obesity of different severity.

scholarly journals Anti-oxidative and antimicrobial activities of Hieracium pilosella L. extracts

2008 ◽  
Vol 73 (5) ◽  
pp. 531-540 ◽  
Author(s):  
Ljiljana Stanojevic ◽  
Mihajlo Stankovic ◽  
Vesna Nikolic ◽  
Ljubisa Nikolic
Keyword(s):  
Salmonella Enteritidis ◽  
Radical Scavenging ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
Quantitative Composition ◽  
Minimal Inhibitory Concentrations ◽  
Qualitative And Quantitative ◽  
Scavenging Effect ◽  
Hieracium Pilosella ◽  
Radical Scavenging Effect

The anti-oxidative and antimicrobial activities of different extracts from Hieracium pilosella L. (Asteraceae) whole plant were investigated. The total dry extracts were determined for all the investigated solvents: methanol, dichloromethane, ethyl acetate and dichloromethane: methanol (9:1). It was found that the highest yield was obtained by extraction with methanol (12.9 g/100 g of dry plant material). Qualitative and quantitative analysis were performed by the HPLC method, using external standards. Chlorogenic acid, apigenin-7-O-glucoside and umbelliferone were detected in the highest quantity in the extracts. The qualitative and quantitative composition of the extracts depends on the solvent used. The 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging effect of the extracts was determined spectrophotometrically. The highest radical scavenging effect was observed in the methanolic extract, both with and without incubation, EC50 = 0.012 and EC50 = 0.015 mg ml-1, respectively. The antimicrobial activities of the extracts towards the bacteria (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Salmonella enteritidis and Klebsiella pneumoniae) and the fungi (Aspergillus niger and Candida albicans) were determined by the disc diffusion method. The minimal inhibitory concentrations were determined for all the investigated extracts against all the mentioned microorganisms.

scholarly journals Chemistry and Biology of Essential Oils of GenusBoswellia

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Hidayat Hussain ◽  
Ahmed Al-Harrasi ◽  
Ahmed Al-Rawahi ◽  
Javid Hussain
Keyword(s):  
Essential Oils ◽  
Current Knowledge ◽  
Biological Activities ◽  
Ethanolic Extract ◽  
Quantitative Composition ◽  
Volatile Constituents ◽  
Traditional Medicines ◽  
Qualitative And Quantitative ◽  
Synthetic Drugs ◽  
Explicit Consideration

The properties ofBoswelliaplants have been exploited for millennia in the traditional medicines of Africa, China, and especially in the Indian Ayurveda. In Western countries, the advent of synthetic drugs has obscured the pharmaceutical use ofBoswellia, until it was reported that an ethanolic extract exerts anti-inflammatory and antiarthritic effects. Frankincense was commonly used for medicinal purposes. This paper aims to provide an overview of current knowledge of the volatile constituents of frankincense, with explicit consideration concerning the diverseBoswelliaspecies. Altogether, more than 340 volatiles inBoswelliahave been reported in the literature. In particular, a broad diversity has been found in the qualitative and quantitative composition of the volatiles with respect to different varieties ofBoswellia. A detailed discussion of the various biological activities ofBoswelliafrankincense is also presented.

The control of the qualitative and quantitative composi-tion of vitamins and tocopherols of various types of vegetable oils

2021 ◽  
pp. 92-95
Author(s):  
Александр Николаевич Остриков ◽  
Наталья Леонидовна Клейменова ◽  
Инэсса Николаевна Болгова ◽  
Максим Васильевич Копылов ◽  
Екатерина Юрьевна Желтоухова
Keyword(s):  
Vegetable Oils ◽  
The Body ◽  
Quantitative Composition ◽  
Vitamin B ◽  
Silybum Marianum ◽  
Qualitative And Quantitative ◽  
Energy Needs ◽  
Wide Range ◽  
Cold Pressed ◽  
Vitamin Activity

Использование растительных масел в рационе человека необходимо для удовлетворения энергетической потребности организма и регулирования биологических процессов. В настоящей работе представлен качественный и количественный состав витаминов и токоферолов различных видов растительных масел, полученных холодным отжимом из выращенных в нашей стране расторопши, горчицы, подсолнечника, рыжика, рапса. Проведен сравнительный анализ литературных источников о наличии витаминов и токоферолов в различных растительных маслах. Количественный и качественный витаминный состав для одного и того же вида масла, по данным разных авторов, варьируется в достаточно широком диапазоне. В ходе исследования изучен витаминный состав пяти растительных масел. Результаты свидетельствуют, что наибольшей витаминной активностью обладают масла рыжиковое, расторопши и горчичное. Установлено наличие витамина А в маслах: рыжиковом (27,15±0,002 мкг%), расторопши (19,07±0,02 мкг%), горчичном (24,77±0,02 мкг%). Витамины В и В присутствуют в маслах горчичном, рыжиковом и расторопши; витамин В определен в горчичном и рыжиковом, В - в рыжиковом и расторопши. В маслах горчичном и расторопши присутствует витамин В. Наиболее богаты витамином Е масла рыжиковое (52,8±0,02 мг%), подсолнечное (48,3±0,02 мг%), расторопши (47,12±0,02 мг%). Витамин К и токоферолы определены во всех растительных маслах. Присутствие b-каротина обнаружено в рыжиковом (1,237±0,004 мг%), расторопши (0,812±0,002 мг%), подсолнечном (0,22±0,02 мг%) и горчичном (0,148±0,002 мг%) маслах. Анализируемые масла холодного отжима можно рассматривать как ценный источник при проектировании новых многоцелевых продуктов или побочных продуктов для промышленного, косметического и фармацевтического использования. The use of vegetable oils in the human diet is necessary to meet the energy needs of the body and regulate biological processes. This work presents the qualitative and quantitative composition of vitamins and tocopherols of various types of vegetable oils obtained by cold pressing from silybum marianum, mustard, sunflower, camelina, rapeseed grown in our country. A comparative analysis of the literature on the presence of vitamins and tocopherols in various vegetable oils has been carried out. The quantitative and qualitative vitamin composition for the same type of oil, according to different authors, varies in a wide range. During the study, the vitamin composition of five vegetable oils was studied. The results indicate that the following oils have the highest vitamin activity: camelina, silybum marianum and mustard. The presence of vitamin A was found in oils: camelina (27.15±0.002 μg%), silybum marianum (19.07±0.02 μg%), mustard (24.77±0.02 μg%). Vitamins B and B are present in mustard, camelina and silybum marianum oils; vitamin B is found in mustard and camelina; B in camelina and silybum marianum. Mustard and silybum marianum oils contain vitamin B. The richest in vitamin E are camelina (52.8±0.02 mg%), sunflower (48.3±0.02 mg%), silybum marianum (47.12±0.02 mg%). Vitamin K and tocopherols are found in all vegetable oils. The presence of b-carotene was found in camelina (1.237±0.004 mg%), silybum marianum (0.812±0.002 mg%), sunflower (0.22±0.02 mg%) and mustard (0.148±0.002 mg%) oils. The analyzed cold-pressed oils can be considered as a valuable resource when designing new multipurpose products or by-products for industrial, cosmetic and pharmaceutical applications.

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