Neuroprotective Effects of Drug-Induced Therapeutic Hypothermia in Central Nervous System Diseases

2017 ◽  
Vol 18 (12) ◽  
Author(s):  
Junwei Ma ◽  
Yibin Wang ◽  
Zhong Wang ◽  
Haiying Li ◽  
Zhimin Wang ◽  
...  
2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Xun Li ◽  
Shifeng Chu ◽  
Yinjiao Liu ◽  
Naihong Chen

Rhubarb is a well-known traditional Chinese medicine; it has been used in China for thousands of years. Rhubarb anthraquinones are the major medicinal ingredients derived from rhubarb including emodin, aloe-emodin, chrysophanol, rhein, physcion, and danthron. These different anthraquinone derivatives alone or in combination play a therapeutic role in central nervous system diseases (CNSD), such as cerebral ischemic stroke, intracerebral hemorrhage, traumatic brain injury, brain tumor, Alzheimer’s disease, depression, and others. We review the experimental studies on these six anthraquinones in the treatment of CNSD by consulting literature published in the last 20 years in PubMed and then give a future perspective on it. In the end of this paper some deficiencies related to these studies also have been pointed out.


1993 ◽  
Vol 74 (1) ◽  
pp. 8-12
Author(s):  
R. Kh. Khafizyaiiova ◽  
I. A. Studentsova ◽  
V. I. Danilov ◽  
I. S. Mokrinskaya ◽  
R. A. Garaev ◽  
...  

An experimental study of dimephpsphone, using different models of the disorders of cerebrum and cerebral circulation functions, reveals cerebroprotcctive properties and normalizing type of the effect on the regulating mechanisms of cerebral circulation. Clinical tests indicate the efficacy of the drug in different central nervous system diseases in neurological and neurosurgical clinics.


Author(s):  
Bernardo F. Sánchez-Dalmau ◽  
Anna Camós-Carreras ◽  
Ruben Torres-Torres ◽  
Johannes Keller ◽  
Laura Sanchez-Vela ◽  
...  

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