Antimicrobial Sensitivity Pattern of Bacterial Pathogens in Urinary Tract Infections in South Delhi, India

2015 ◽  
Vol 9 (4) ◽  
pp. 271-275 ◽  
Author(s):  
Mohammad Akhtar ◽  
Nehal Mohsin ◽  
Ahmad Zahak ◽  
Mohammad Ain ◽  
P.K Pillai ◽  
...  
Author(s):  
Nikhil S. Yadav ◽  
Swanand S. Pathak

Background: Urinary tract infections are commonly seen in febrile children, high incidence of Vesico Ureteral Reflux (VUR) is frequently seen in paediatric patient which is of concern as it may lead to renal scarring. Despite presence of established clinical guidelines there is disparity amongst physician in the diagnosis and treatment of UTI, some physician prescribes taking into consideration the symptoms, some prescribe on the basis of smell and colour and some rely on urine culture and sensitivity report. There is dearth of studies in many tertiary health care centers regarding antimicrobial use. Authors conducted this study to evaluate antimicrobial sensitivity pattern, efficacy and cost effectiveness of antimicrobials used for UTI in children.Methods: Patients of urinary tract infection <13 years of age were included in the study. Symptoms of patient i.e. pain in abdomen, haematuria, increased frequency of urination and degree of fever were recorded. Efficacy was measured through calculating degree of defervescence per hour. Cost effective model was prepared by calculating cost effective ratio i.e. dividing cost of antimicrobial required to bring down the fever and degree through which fever came down.Results: E. coli was the most common pathogen isolated from urine positive culture (69.07%). Nitrofurantoin has shown highest sensitivity to all uropathogens (72.73%). Cotrimoxazole, ciprofloxacin and nitrofurantoin were found to be most cost effective.Conclusions: In this current study authors found E coli is the most common uropathogen isolated. Ceftriaxone, cefixime, cotrimoxazole and amikacin were found to be most efficacious. Cotrimoxazole, ciprofloxacin and nitrofurantoin were found to be most cost effective.


2020 ◽  
Vol 33 (2) ◽  
pp. 27-31
Author(s):  
Laila Shamima Sharmin ◽  
Md Azizul Haque ◽  
Fardoushi Begum ◽  
ASM Kazi Shamim Parvez ◽  
Md Belal Uddin

Pediatric urinary tract infections (UTI) are associated with significant morbidity and potential long term complication like extensive renal scarring leading to end stage renal disease. Prompt diagnosis and early initiation of treatment is necessary to prevent long term complications. Knowledge about bacteriological profile of pediatric urinary tract infections and their antimicrobial sensitivity pattern is helpful for initiation of empirical antibiotic treatment. The aim of this study was to identify the causative bacteria and antimicrobial sensitivity pattern of community acquired UTI in children attending outpatient department of a tertiary level hospital of Bangladesh. This was a cross-sectional study conducted in pediatric outpatient department of Rajshahi Medical College Hospital, Bangladesh over 6 month period from 1st January 2017 to 30th June 2017. Children aged < 12 year who presented with clinical features suggestive of urinary tract infection were subjected for urinary routine and microscopic examination and culture. Colony counts of the culture positive cases were done and antibiotic sensitivity and resistance patterns were studied. Samples with colony count of ≥ 105 CFU/ml were considered significant. Among the 134 clinically suspected cases significant bacteriuria was found in 81 (60.45%) children. Escherichia coli was the most common isolate (74.1%) followed by Proteus (9.8%), Klebsiella spp. (8.6%), Pseudomonas (6.2%) and Staphylococcus saprophyticus (1.2%). E. coli was found to be highly sensitive to imipenem, amikacin, nitrofurantoin and ciprofloxacin. Klebsiella showed good sensitivity against ciprofloxacin and imipenem whereas proteus, Pseudomonas and Staphylococcus saprophyticus showed sensitivity against imipenem, amikacin and ciprofloxacin. Increased resistance was noted against the commonly used empirical antibiotics such as cephradin, cefuroxime, cefixime, ceftriaxone and co-trimoxazole. Therefore, selection of empirical therapy should be based on local bacteriological profile and their antimicrobial sensitivity pattern. TAJ 2020; 33(2): 27-31


2017 ◽  
Vol 8 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Jabin Akhter ◽  
Sharmeen Ahmed ◽  
Shaheda Anwar

Enterococci were frequently considered to be commensal organism and were ignored when isolated in clinical laboratory. But recently due to its capability of causing variety of infections, especially in hospitalized patients and difference in antimicrobial sensitivity of each species to varying antibiotics the present study wasundertaken with a view at characterizing the clinical isolates of enterococcus, recovered from the cases of urinary tract infections (UTI). A total of 59 Enterococci were isolated from UTI patient for a period of 1 year. In the present study it was the 3rd leading organism causing UTI. They were speciated by an identification system based on the phenotypic characteristics of enterococcus species and their antimicrobial sensitivity pattern was determined. Most of the isolates were E.faecalis 42(71.18%) followed by E.faecium accounted for 10(16.94%),E.avium 1(2.43%), E.raff 1(2.43%) and 5(8.47%) remained unidentified. E.faecium showed increased resistance to amoxicillin (90%), co-trimoxazole (80%), ciprofloxacin (70%), gentamycin (80%), ceftriaxone (90%), and cefuroxime (80%). Most of the E.faecalis was resistant to amoxicillin (66.66%), cotrimoxazole (71.42%), ciprofloxacin (76.19%), gentamycin (71.42%), ceftriaxone (64.28%) and cefuroxime (80.95%). Multidrug-resistant enterococci are emerging as a leading nosocomial uropathogen. Identification of species along with knowledge of the antimicrobial resistance profile may ultimately contribute to development of strategies for prevention and to formulate treatment guidelines for infections caused by enterococci.Bangladesh J Med Microbiol 2014; 08 (01): 16-20


2021 ◽  
Author(s):  
◽  
Gerald Turyatunga

Background: A urinary tract infection (UTIs) is a common type of infection caused by bacteria that travel up the urethra to the bladder. Globally, it is reported that 150 million people are diagnosed with a UTI annually, costing the world economy over 6 million US dollars in treatment and work loss. Studies conducted in the in-patients pediatric ward of Muhimbili Hospital in Tanzania and Mulago National Referral Hospital in Uganda between five to ten years reported the prevalence of UTI to be 16.8% and 14.6% respectively. On average at Kam Medical Consult Clinic, patients who turn up in the laboratory are about 20%, and 50% of patients present with recurring UTIs clinically. Therefore,  there is a need to establish and investigate the prevalence of bacterial pathogens associated with UTI and multiple pathogens that are not known. Methodology: The cross-sectional study was carried out at Kam medical consult clinic (KMCC) located in Kafeero zone Mulago II Kawempe division. The study population was adults and children presenting with symptoms of urinary tract infection. 120 Midstream urine Samples were collected from patients presenting clinical signs of UTI. The diagnosis was done through macroscopy dry chemistry, microscopy, and culture. Results Among the sampled population, 33% of males had urinary tract infections while 67% of females had urinary tract infections.  88.5% were outpatients while 11.5 % were in-patients The overall prevalence of UTI among patients was 63.3% with children aged (1-10) having a prevalence of 5.8 %. Conclusion and recommendation: E.coli is an etiological agent causing UTIs in male and female patients presenting UTI at Kam Medical Consult Clinic. Other etiological agents included Klebsiella, Coliform, Enterococcus species, staphylococcus aureus, pseudomonas species, and candida species. There is a need to monitor the profile of etiological bacteria of UTI through culture and sensitivity regularly. 


2020 ◽  
Vol 241 ◽  
pp. 108540
Author(s):  
Zhuoling Yu ◽  
Yao Wang ◽  
Yanyun Chen ◽  
Min Huang ◽  
Yang Wang ◽  
...  

2015 ◽  
Author(s):  
Holger Becker ◽  
Nadine Hlawatsch ◽  
Tommy Haraldsson ◽  
Wouter van der Wijngaart ◽  
Anders Lind ◽  
...  

2019 ◽  
Vol 30 (1) ◽  
pp. 43 ◽  
Author(s):  
Ahmed Sallem Alganady

One of the most prevalent bacterial infections are urinary tract infections (UTIs), which affect any age of individuals and they appear higher in women than men, the major problem regarding UTIs are the difficult of antibiotics treatment, due to bacterial pathogens resistance. So, the current study aimed to detect the types of bacterial pathogens and their antibiotics susceptibility of UTIs in Taiz Governorate – Yemen. In this cohort study, one hundred and ten (110) mid-stream urine samples were collected from a symptomatic UTIs patient, the type of bacterial pathogens was identified by using standard bacteriological media and biochemical tests and determine the antibiotics sensitivity to these bacteria using disk diffusion tests. Out of one hundred and ten of urine samples:: 65 of patients were females and 45 were males and the bacterial growth in these patients were sixty-four [46(58.2%)] : (33.7%) were females and (24.5%) were males. Our findings showed that the types of bacterial pathogens include: Escherichia coli (32.7%), Klebsiellapneumoniae (9.1%), Staphylococcus aureus (6.4%), Proteus mirabilis (5.5%) and Pseudomonas aeruginosa (4.5%). The majority (57.9%) of the isolates were from female. The prevalence of UTIs is high among patients with age between 16-30 years with the incident rate 20.9 %, age groups 1-15 years have the lower incidence rate 5.5%. UTIs were more prevalent among the rural area population, there were 50% than the population of the city center, there were 8.2% and the rate of infections were more prevalent among illiterate (no read and write) patients with incidence rate 44.5% , compared to literate (read and write) patients 13.6%. Also, our results showed that the sensitivity test against bacterial pathogens as All bacterial isolates was more sensitive to Ciprofloxacin, followed by Amikacin, Gentamycin , Cefotaxime (except Staphylococcus aureus Cefotaxime (42.9%) and Ceftriaxone (except Staphylococcus aureus) (28.6%). Staphylococcus aureus isolated also were sensitive to Erythromycin, Rifampicin, and Cephalothin. Finally, all isolates showed very high rate of resistance against Amoxicillin, ampicillin and penicillin G.


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