Radiographic and CT Evaluation of Recombinant Human Bone Morphogenetic Protein-2–Assisted Spinal Interbody Fusion

2011 ◽  
Vol 197 (1) ◽  
pp. W128-W133 ◽  
Author(s):  
Anil Sethi ◽  
Joseph Craig ◽  
Stephen Bartol ◽  
Wei Chen ◽  
Mark Jacobson ◽  
...  
Keyword(s):  
Bone Morphogenetic Protein ◽  
Interbody Fusion ◽  
Human Bone ◽  
Bone Morphogenetic Protein 2 ◽  
Morphogenetic Protein ◽  
Human Bone Morphogenetic Protein ◽  
Ct Evaluation ◽  
Recombinant Human Bone

Radiographic and CT Evaluation of Recombinant Human Bone Morphogenetic Protein-2-Assisted Cervical Spinal Interbody Fusion

2017 ◽  
Vol 17 (10) ◽  
pp. S110
Author(s):  
Luke J. Weisbrod ◽  
John D. Leever ◽  
J. Kenneth Burkus ◽  
Kevin T. Foley ◽  
Randall F. Dryer ◽  
...  
Keyword(s):  
Bone Morphogenetic Protein ◽  
Interbody Fusion ◽  
Human Bone ◽  
Bone Morphogenetic Protein 2 ◽  
Morphogenetic Protein ◽  
Human Bone Morphogenetic Protein ◽  
Ct Evaluation ◽  
Recombinant Human Bone

scholarly journals Lumbar interbody fusion after treatment with recombinant human bone morphogenetic protein–2 added to 70:30 poly(L-lactide-co-D,L-lactide) bioresorbable implants

2004 ◽  
Vol 16 (3) ◽  
pp. 1-4 ◽  
Author(s):  
Todd H. Lanman ◽  
Thomas J. Hopkins
Keyword(s):  
Bone Graft ◽  
Bone Morphogenetic Protein ◽  
Interbody Fusion ◽  
Human Bone ◽  
Bone Morphogenetic Protein 2 ◽  
Ct Scans ◽  
Lumbar Interbody Fusion ◽  
Morphogenetic Protein ◽  
Human Bone Morphogenetic Protein ◽  
Recombinant Human Bone

Object To evaluate the effectiveness of recombinant human bone morphogenetic protein–2 (rhBMP-2) combined with a bioresorbable implant, the authors conducted a prospective study of 43 patients with degenerative lumbar disc disease who underwent transforaminal lumbar interbody fusion. Methods The authors used Infuse bone graft, which consisted of rhBMP-2 applied to an absorbable collagen sponge and contained within a HYDROSORB Telamon bioresorbable implant to perform the fusion. Multilevel fusions were performed in 30% of the 43 patients, for a total of 57 levels. At 6 months postoperatively, x-ray films and computerized tomography (CT) scans demonstrated solid fusion in 98% of 41 patients. Improvement from the baseline Oswestry Disability Rating was demonstrated at 6 months postoperatively in 68% of the patients, based on the Oswestry Disability Questionnaire. At 12 months all 11 patients in whom CT scans were obtained showed complete bridging of bone; there were no device-related complications. Conclusions Results in this series provide evidence of the feasibility of using HYDROSORB Telamon biore-sorbable spacers in combination with Infuse bone graft for lumbar spine fusion.

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