scholarly journals Application of lysozyme and dequalinium chloride in the treatment of acute respiratory diseases of the upper respiratory tract in children

2018 ◽  
Vol 13 (6) ◽  
pp. 576-584
Author(s):  
O.Ye. Abaturov ◽  
O.O. Ahafonova ◽  
N.M. Tokarieva
Keyword(s):  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Upper Respiratory Tract ◽  
Acute Respiratory Diseases ◽  
Upper Respiratory ◽  
Dequalinium Chloride

scholarly journals Efficiency of the irs-19 aerosol vaccine in children with relapsing diseases of upper respiratory tract

2021 ◽  
Vol 82 (1) ◽  
pp. 15-16
Author(s):  
G. A. Makovetskaya ◽  
V. V. Zhestkova ◽  
T. L. Kuznetsova
Keyword(s):  
Infectious Diseases ◽  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Upper Respiratory Tract ◽  
Acute Respiratory Diseases ◽  
Upper Respiratory

The use of the IRS-19 aerosol vaccine results in decreasing of the rate of the infectious diseases of otorhinolaryngologic organs in children suffering from adenoids, sinusitis, complications of acute respiratory diseases.

scholarly journals Topical aspects of the use of phytopreparations in acute infectious and inflammatory diseases of the upper respiratory tract

2021 ◽  
pp. 36-42
Author(s):  
V. M. Svistushkin ◽  
S. V. Morozova ◽  
L. A. Keda
Keyword(s):  
Respiratory Tract ◽  
Respiratory Infections ◽  
Inflammatory Diseases ◽  
Smooth Muscles ◽  
Severe Allergic Reaction ◽  
Nasal Discharge ◽  
Upper Respiratory Tract ◽  
General Weakness ◽  
Acute Respiratory Diseases ◽  
Upper Respiratory

Acute infectious and inflammatory diseases of the upper respiratory tract today belong to the category of the most common pathological conditions. Most often they occur in the form of acute nasopharyngitis, acute rhinosinusitis and acute laryngitis, the clinical of which consists of such symptoms as general weakness, hyperthermia, nasal blockage and nasal discharge, dysosmia, pain and tickling in the throat, cough, dysphonia. The need to select a safe and effective mucoactive therapy justifies the use of the phytopreparation in this pathology, the main active ingredient of which is an extract of ivy leaves. Also in the composition of the drug includes anise oil, peppermint oil, eucalyptus oil and levomenthol. The mechanism of action of is associated with α-hederin contained in ivy leaves. This substance, binding to the beta-adrenoreceptors of the bronchi, causes relaxation of their smooth muscles. In addition, thanks to the saponins contained in the leaves of common ivy, a mucolytic and expectorant effect is achieved. Literature data show that ivy leaf preparations significantly reduce the severity of acute respiratory infections of the upper respiratory tract. Virtually none of the patients had severe side effects. Allergic reactions were recorded in less than 0.5% of cases, with no mention of a severe allergic reaction of the anaphylaxis type. Thus, the drug of plant origin in the form of drops can be successfully used in patients with symptoms of acute respiratory diseases.

scholarly journals Department of Microbiology, Science and Research Branch, Islamic Azad University, Tehran, Iran

2018 ◽  
Vol 68 (4) ◽  
pp. 647
Author(s):  
H MOOMIVAND ◽  
SA POURBAKHSH ◽  
M JAMSHIDIAN
Keyword(s):  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Upper Respiratory Tract ◽  
Culture Methods ◽  
Isolation And Identification ◽  
Air Sacs ◽  
Upper Respiratory ◽  
Alignment Analysis ◽  
Science And Research

In ostriches, mycoplasmas are generally associated with respiratory diseases and causes rhino-tracheitis, airsacculitis and inflammation of the upper respiratory tract. The aim of current study was the isolation and identification of pathogenic mycoplasmas in ostrich farms of Iran by the use of PCR and culture methods. In this study, mycoplasmas were isolated from ostrich slaughterhouse; 114 samples were collected from ostriches with respiratory signs and were cultured and PCR methods along with alignment were used to detect the mycoplasmas. For this purpose lung, trachea and air sacs were evaluated. The results indicated that 21.05% of samples were positive in PCR assayand from them 7.89% and 14% was M. gallisepticum and M. synoviae, respectively. The highest rate of M. gallisepticum and M. synoviae was detected in lung, airsacs and trachea. Alignment analysis demonstrated that the M. gallisepticum strains detected in our study have 97% homology to 06/14, 05/14 and 16S strains. In addition, M. synoviae strains have 99% and 98% homology to MSR-812, MSR-795 and MSR-1019 strains. One of the M. synoviae strains has 82% homology to ABSfsdMS2011 strain. The results of our study showed that ostriches in Iran were infected with chicken mycoplasmas but the pathogenesis of them in ostrich respiratory should be further evaluated.

scholarly journals CONDITIONS OF THE DEVELOPMENT AND PECULIARITIES OF THE COURSE OF RESPIRATORY DISEASES IN SMELTERS OF TITANIUM ALLOYS

2018 ◽  
Vol 97 (1) ◽  
pp. 65-69
Author(s):  
Elena M. Vlasova ◽  
N. K. Voznesenskiy ◽  
V. B. Alekseev ◽  
A. A. Vorobeva
Keyword(s):  
Respiratory Tract ◽  
Titanium Alloys ◽  
Working Conditions ◽  
Prevalence Rate ◽  
Respiratory Diseases ◽  
Atrophic Rhinitis ◽  
Upper Respiratory Tract ◽  
Subsequent Formation ◽  
Industrial Dust ◽  
Upper Respiratory

The working conditions, occupational and non-occupational risk factors, prevalence rate and peculiarities of the course of respiratory diseases in smelters of titanium alloys were studied. Working conditions of smelters are estimated as harmful (class of working conditions: 3.3-3.4.) due to factors: heating microclimate, chemicals (chlorine and hydrochloride, sulfur dioxide, nitrogen oxide), industrial dust. A feature of the respirable dust fraction is the high content of titanium oxide particles of the PM10 dimension. There was made an analysis of the health status of workers exposed to industrial dust, depending on the length of service. Diseases of the upper respiratory tract in smelters of titanium alloys were shown to be prevalent, simple catarrhal nasopharyngitis prevails with the subsequent formation of atrophic rhinitis, its prevalence rate among smelters of titanium alloys increases with the experience. The peculiarity of the development of diseases of the upper respiratory tract in smelters of titanium alloys are: deterioration of nasal breathing in workers with experience of from 1 year to 5 years already, in patients with experience from 10 to 15 years the prevalence of catarrhal nasopharyngitis and atrophic rhinitis as its outcome in cases with experience from 15 to 20 years. The bronchial damage in the smelters of titanium alloys develops under the experience more than 5 years. The clinical forms are dominated by the phenomena of catarrhal bronchitis followed by obstruction of the bronchi progressing with the experience, with the formation of irreversible ventilation disorders. With the depletion of antioxidant protection, as a rule, with long duration of the exposure of up to 10 years, aseptic inflammation is formed, which is pronounced clinically as catarrhal endobronchitis. This is a partially reversible pathological process. The described features of the development and course of respiratory diseases in smelters of titanium alloys should be taken into account during periodic medical examinations in order to timely prevent them

scholarly journals Assessment of Duration of Adaptation to Conditions of Learning in Cadets of Military Educational Institutions

2021 ◽  
pp. 43-49
Author(s):  
RS Rakhmanov ◽  
ЕS Bogomolova ◽  
AV Tarasov ◽  
SA Razgulin ◽  
МА Shaposhnikova ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Respiratory Tract Infections ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Resident Students ◽  
Learning Conditions ◽  
Upper Respiratory ◽  
Tract Infections ◽  
Conditions Of Learning

Introduction. It is relevant to determine periods of adaptation of local and non-resident students coming from other Russian regions to learning conditions. The objective of our study was to measure duration of cadets’ adaptation to the learning environment as assessed by the incidence of respiratory diseases in view of synergistic effects of health risk factors in the Kaliningrad enclave. Materials and methods. We conducted a retrospective analysis of the incidence of respiratory diseases in cadets of two military universities (n = 3,381, n = 2,013) by cohorts (local and non-resident students) for five academic years in general and by year. Results. The proportion of respiratory diseases in university cadets was as high as 70.9 ± 2.0 and 52.1 ± 1.1 % in Universities 1 and 2, respectively. The share of respiratory diseases in the first and fifth-year students was 72.3 and 59.9 % in University 1,and 60.3 and 38.1 % in University 2, respectively. The respiratory disease incidence in non-resident cadets was 1.8 and 1.2 times higher than that in locals: 1,102.6 ± 6.2 versus 617.7 ± 24.5 ‰ and 477.6 ± 14.1 versus 388.2 ± 16.1 ‰ (p = 0.001) in Universities 1 and 2, respectively. We found differences in the rates of acute sinusitis, acute tonsillitis, upper respiratory tract infections and influenza, community-acquired pneumonia, and lower respiratory tract infections between local and non-resident cadets. In the second university, differences in the incidence of acute sinusitis and upper respiratory tract infections were still observed in third-year students while in the first university they were still pronounced in cadets during the fourth year of study. We suppose that they might be attributed to learning conditions, ratios of local to non-resident cadets, differences in living conditions and nutrition between the students. Conclusion. Duration of the period of adaptation of military university cadets to conditions of learning is influenced by a synergistic effect of adverse environmental factors. Adaptation of non-resident cadets lasts longer due to acclimatization to weather and climate conditions of the enclave. The incidence of respiratory diseases proves the differences in learning conditions between the universities.

RELATIONSHIP OF ABNORMALITIES OF THE UPPER RESPIRATORY TRACT TO MINOR RESPIRATORY DISEASES*

1933 ◽  
Vol 17 (3) ◽  
pp. 743-760
Author(s):  
J. A. DOULL ◽  
V. A. VAN VOLKENBURGH ◽  
N. B. HERMAN ◽  
W. M. GAFAFER
Keyword(s):  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Upper Respiratory Tract ◽  
Upper Respiratory ◽  
Relationship Of

scholarly journals Respiratory microbiota disorders in children with neurological disabilities at repeated respiratory diseases

2021 ◽  
pp. 53-56
Author(s):  
Olena Koreniuk
Keyword(s):  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Clinical Symptoms ◽  
Invasive Technique ◽  
Upper Respiratory Tract ◽  
Bronchopulmonary Diseases ◽  
Upper Respiratory ◽  
Neurological Pathology ◽  
Respiratory Microbiota ◽  
Neurological Disabilities

  The relevance of the problem of recurrent respiratory diseases in children with severe neurological pathology is due to the high frequency, severity of clinical symptoms and the protracted nature of their exacerbations, as well as the tendency to chronicity of the pathological process. The aim of the research was to study the respiratory microbiota to optimize antibacterial therapy of recurrent respiratory diseases. Materials and methods: the 16 children with severe neurological pathology at repeated respiratory diseases were examined. We used a microbiological examination of the upper respiratory tract using a deep smear from the oropharynx to identify a possible causative agent of the disease. Research results: the pronounced imbalance of the respiratory microbiota, corresponding to II and III degrees of dysbiotic disorders, was revealed in the examined children. The feature of the microflora of the upper respiratory tract was the dominance of Pseudomonas aeroginosa, intestinal opportunistic microflora (Klebsiella pneumoniae, Proteus vulgaris) and their frequent combination with Streptococcus pyogenus, Staphylococcus aureus and yeast-like mushrooms of the Сandida genus. The maximum degree of respiratory microbiota disorders was noted in the group of children with congenital malformations of the brain and correlated with the severity of bronchopulmonary diseases. The analysis of the pathogenic microflora sensitivity to antibiotics showed high resistance of the identified microorganisms to most medicines. Conclusions: respiratory pathology in children with neurological disabilities is characterized by a recurrent and chronic bronchitis with a tendency of a protracted course which determines the duration of antibiotic therapy. The use of a non-invasive technique for the respiratory microbiota studying makes it possible to identify suspected pathogens of bronchopulmonary diseases and optimize their treatment

scholarly journals Possibilities of using multidirectional immunomodulators for acute and recurrent infectious and inflammatory diseases of the upper respiratory tract

2021 ◽  
pp. 89-95
Author(s):  
S. V. Morozova ◽  
L. V. Selezneva
Keyword(s):  
Immune System ◽  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Inflammatory Diseases ◽  
Mechanisms Of Action ◽  
Biologically Active ◽  
Upper Respiratory Tract ◽  
Starting Point ◽  
Upper Respiratory

In many countries, with the prevention of acute respiratory diseases in children and adults, the use of various types of biologically active substances of natural and synthetic origin, called immunostimulants of various mechanisms of action, has been introduced. The purpose of this article is to provide a useful overview of main roles of available immunostimulants and their potential for use in inflammatory diseases of the upper respiratory tract. The article discusses aspects of the clinical use of immunomodulatory drugs in acute and recurrent infectious and inflammatory diseases of the respiratory tract (SARS-CoV-2 included). The mechanisms of action of immunomodulators on the immune system are briefly outlined. On the drug Imunorix the evidence base of mechanisms of correction of the immune system in respiratory diseases of the upper respiratory tract is given, as well as the analysis of the clinical efficacy of drug. The use of immunostimulator to increase the level of immunoglobulins (IgA, IgM, IgG) and subpopulations of T-lymphocytes (CD3 +, CD4 +). Also, the use of the drug has shown its usefulness in the appointment of antibacterial drugs in the treatment of upper respiratory tract infectious diseases. This article also provides an overview of recent clinical studies of drug. Researchers from various countries have tried to better clarify and define the mechanisms of action of immunostimulator both in vitro and in vivo. Of course, the improvement in research methodology over the past 20 years, and the acquired knowledge in various areas of clinical immunology, should become the starting point for further research on the drug. Randomized controlled trials of the trial use of the drug in the prevention of acute respiratory infections.

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