scholarly journals Capturing High-level Nondeterminism in Concurrent Programs for Practical Concurrency Model Agnostic Record & Replay

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Dominik Aumayr ◽  
Stefan Marr ◽  
Sophie Kaleba ◽  
Elisa Gonzalez Boix ◽  
Hanspeter Mössenböck
Keyword(s):  
Concurrent Programs ◽  
Concurrency Model ◽  
High Level

High-level language debugging for concurrent programs

1990 ◽  
Vol 8 (4) ◽  
pp. 311-336 ◽  
Author(s):  
German S. Goldszmidt ◽  
Shaula Yemini ◽  
Shmuel Katz
Keyword(s):  
Concurrent Programs ◽  
High Level Language ◽  
High Level

Transactional events

2008 ◽  
Vol 18 (5-6) ◽  
pp. 649-706 ◽  
Author(s):  
KEVIN DONNELLY ◽  
MATTHEW FLUET
Keyword(s):  
Message Passing ◽  
Formal Semantics ◽  
Concurrent Programming ◽  
Expressive Power ◽  
Detailed Account ◽  
Concurrent Programs ◽  
Compositional Reasoning ◽  
Compositional Structure ◽  
High Level

AbstractConcurrent programs require high-level abstractions in order to manage complexity and enable compositional reasoning. In this paper, we introduce a novel concurrency abstraction, dubbed transactional events, which combines first-class synchronous message passing events with all-or-nothing transactions. This combination enables simple solutions to interesting problems in concurrent programming. For example, guarded synchronous receive can be implemented as an abstract transactional event, whereas in other languages it requires a non-abstract, non-modular protocol. As another example, three-way rendezvous can be implemented as an abstract transactional event, which is impossible using first-class events alone. Both solutions are easy to code and easy to reason about.The expressive power of transactional events arises from a sequencing combinator whose semantics enforces an all-or-nothing transactional property – either both of the constituent events synchronize in sequence or neither of them synchronizes. This sequencing combinator, along with a non-deterministic choice combinator, gives transactional events the compositional structure of a monad-with-plus. We provide a formal semantics for transactional events and give a detailed account of an implementation.

scholarly journals Extending Non-Termination Proof Techniques to Asynchronously Communicating Concurrent Programs

10.29007/c7v2 ◽  
2018 ◽  
Author(s):  
Matthias Kuntz ◽  
Stefan Leue ◽  
Christoph Scheben
Keyword(s):  
Case Studies ◽  
Data Structures ◽  
Theorem Proving ◽  
Asynchronous Communication ◽  
Control Flow ◽  
Concurrent Programs ◽  
Prototype Tool ◽  
Proof Techniques ◽  
High Level ◽  
Termination Proofs

Currently, there are no approaches known that allow for non-termination proofs of concurrent programs which account for asynchronous communication via FIFO message queues. Those programs may be written in high-level languages such as Java or Promela. We present a first approach to prove non-termination for such programs. In addition to integers, the programs that we consider may contain queues as data structures. We present a representation of queues and the operations on them in the domain of integers, and generate invariants that help us prove non-termination of selected control flow loops using a theorem proving approach. We illustrate this approach by applying a prototype tool implementation to a number of case studies.

scholarly journals Detecting concurrency anomalies in transactional memory programs

2011 ◽  
Vol 8 (2) ◽  
pp. 534-548 ◽  
Author(s):  
João Lourenço ◽  
Diogo Sousa ◽  
Bruno Teixeira ◽  
Ricardo Dias
Keyword(s):  
Shared Memory ◽  
Static Analysis ◽  
Transactional Memory ◽  
Analysis Procedure ◽  
Concurrent Programs ◽  
Program Correctness ◽  
Classic Case ◽  
Analysis Techniques ◽  
High Level ◽  
Different Sources

Concurrent programs may suffer from concurrency anomalies that may lead to erroneous and unpredictable program behaviors. To ensure program correctness, these anomalies must be diagnosed and corrected. This paper addresses the detection of both low- and high-level anomalies in the Transactional Memory setting. We propose a static analysis procedure and a framework to address Transactional Memory anomalies. We start by dealing with the classic case of low-level dataraces, identifying concurrent accesses to shared memory cells that are not protected within the scope of a memory transaction. Then, we address the case of high-level dataraces, bringing the programmer?s attention to pairs of memory transactions that were misspecified and should have been combined into a single transaction. Our framework was applied to a set of programs, collected form different sources, containing well known low- and high-level anomalies. The framework demonstrated to be accurate, confirming the effectiveness of using static analysis techniques to precisely identify concurrency anomalies in Transactional Memory programs.

scholarly journals ConFuzz: Coverage-Guided Property Fuzzing for Event-Driven Programs

2021 ◽  
pp. 127-144
Author(s):  
Sumit Padhiyar ◽  
K. C. Sivaramakrishnan
Keyword(s):  
Experimental Results ◽  
Concurrent Programs ◽  
Concurrent Schedules ◽  
Concurrency Bugs ◽  
Concurrent Program ◽  
Novel Technique ◽  
Event Driven ◽  
Bug Finding ◽  
High Level ◽  
Concurrency Bug

AbstractBug-free concurrent programs are hard to write due to non-determinism arising out of concurrency and program inputs. Since concurrency bugs typically manifest under specific inputs and thread schedules, conventional testing methodologies for concurrent programs like stress testing and random testing, which explore random schedules, have a strong chance of missing buggy schedules.In this paper, we introduce a novel technique that combines property-based testing with mutation-based, grey box fuzzer, applied to event-driven OCaml programs. We have implemented this technique in , a directed concurrency bug-finding tool for event-driven OCaml programs. Using , programmers specify high-level program properties as assertions in the concurrent program. uses the popular greybox fuzzer AFL to generate inputs as well as concurrent schedules to maximise the likelihood of finding new schedules and paths in the program so as to make the assertion fail. does not require any modification to the concurrent program, which is free to perform arbitrary I/O operations. Our experimental results show that is easy-to-use, effective, detects concurrency bugs faster than Node.Fz - a random fuzzer for event-driven JavaScript programs, and is able to reproduce known concurrency bugs in widely used OCaml libraries.

Transcription factor/DNA interactions visualized by electron spectroscopic imaging

1992 ◽  
Vol 50 (1) ◽  
pp. 450-451
Author(s):  
David P. Bazett-Jones ◽  
Mark L. Brown
Keyword(s):  
Transcription Factor ◽  
Dna Sequences ◽  
Transcription Initiation ◽  
Molecular Mechanisms ◽  
Phosphorus Content ◽  
Spectroscopic Imaging ◽  
Electron Spectroscopic Imaging ◽  
Dna Backbone ◽  
Two Parameters ◽  
High Level

A multisubunit RNA polymerase enzyme is ultimately responsible for transcription initiation and elongation of RNA, but recognition of the proper start site by the enzyme is regulated by general, temporal and gene-specific trans-factors interacting at promoter and enhancer DNA sequences. To understand the molecular mechanisms which precisely regulate the transcription initiation event, it is crucial to elucidate the structure of the transcription factor/DNA complexes involved. Electron spectroscopic imaging (ESI) provides the opportunity to visualize individual DNA molecules. Enhancement of DNA contrast with ESI is accomplished by imaging with electrons that have interacted with inner shell electrons of phosphorus in the DNA backbone. Phosphorus detection at this intermediately high level of resolution (≈lnm) permits selective imaging of the DNA, to determine whether the protein factors compact, bend or wrap the DNA. Simultaneously, mass analysis and phosphorus content can be measured quantitatively, using adjacent DNA or tobacco mosaic virus (TMV) as mass and phosphorus standards. These two parameters provide stoichiometric information relating the ratios of protein:DNA content.

Advances in Stem Instrumentation for Biology

1990 ◽  
Vol 48 (1) ◽  
pp. 362-363
Author(s):  
J. S. Wall
Keyword(s):  
Scanning Transmission Electron Microscope ◽  
Carbon Films ◽  
Specimen Preparation ◽  
Material Deposition ◽  
Active User ◽  
Percent Improvement ◽  
Scanning Transmission ◽  
The Moment ◽  
Film Substrate ◽  
High Level

The forte of the Scanning transmission Electron Microscope (STEM) is high resolution imaging with high contrast on thin specimens, as demonstrated by visualization of single heavy atoms. of equal importance for biology is the efficient utilization of all available signals, permitting low dose imaging of unstained single molecules such as DNA.Our work at Brookhaven has concentrated on: 1) design and construction of instruments optimized for a narrow range of biological applications and 2) use of such instruments in a very active user/collaborator program. Therefore our program is highly interactive with a strong emphasis on producing results which are interpretable with a high level of confidence.The major challenge we face at the moment is specimen preparation. The resolution of the STEM is better than 2.5 A, but measurements of resolution vs. dose level off at a resolution of 20 A at a dose of 10 el/A2 on a well-behaved biological specimen such as TMV (tobacco mosaic virus). To track down this problem we are examining all aspects of specimen preparation: purification of biological material, deposition on the thin film substrate, washing, fast freezing and freeze drying. As we attempt to improve our equipment/technique, we use image analysis of TMV internal controls included in all STEM samples as a monitor sensitive enough to detect even a few percent improvement. For delicate specimens, carbon films can be very harsh-leading to disruption of the sample. Therefore we are developing conducting polymer films as alternative substrates, as described elsewhere in these Proceedings. For specimen preparation studies, we have identified (from our user/collaborator program ) a variety of “canary” specimens, each uniquely sensitive to one particular aspect of sample preparation, so we can attempt to separate the variables involved.

A Questionnaire Survey of Current Rehabilitation Practices for Adults With Normal Hearing Sensitivity Who Experience Auditory Difficulties

2020 ◽  
Vol 29 (4) ◽  
pp. 738-761
Author(s):  
Tess K. Koerner ◽  
Melissa A. Papesh ◽  
Frederick J. Gallun
Keyword(s):  
Hearing Aids ◽  
Questionnaire Survey ◽  
Patient Population ◽  
Clinical Care ◽  
Normal Hearing ◽  
Auditory Training ◽  
Training Methods ◽  
Hearing Sensitivity ◽  
Considerable Benefit ◽  
High Level

Purpose A questionnaire survey was conducted to collect information from clinical audiologists about rehabilitation options for adult patients who report significant auditory difficulties despite having normal or near-normal hearing sensitivity. This work aimed to provide more information about what audiologists are currently doing in the clinic to manage auditory difficulties in this patient population and their views on the efficacy of recommended rehabilitation methods. Method A questionnaire survey containing multiple-choice and open-ended questions was developed and disseminated online. Invitations to participate were delivered via e-mail listservs and through business cards provided at annual audiology conferences. All responses were anonymous at the time of data collection. Results Responses were collected from 209 participants. The majority of participants reported seeing at least one normal-hearing patient per month who reported significant communication difficulties. However, few respondents indicated that their location had specific protocols for the treatment of these patients. Counseling was reported as the most frequent rehabilitation method, but results revealed that audiologists across various work settings are also successfully starting to fit patients with mild-gain hearing aids. Responses indicated that patient compliance with computer-based auditory training methods was regarded as low, with patients generally preferring device-based rehabilitation options. Conclusions Results from this questionnaire survey strongly suggest that audiologists frequently see normal-hearing patients who report auditory difficulties, but that few clinicians are equipped with established protocols for diagnosis and management. While many feel that mild-gain hearing aids provide considerable benefit for these patients, very little research has been conducted to date to support the use of hearing aids or other rehabilitation options for this unique patient population. This study reveals the critical need for additional research to establish evidence-based practice guidelines that will empower clinicians to provide a high level of clinical care and effective rehabilitation strategies to these patients.

805: High-Level Cyclin D1 is Associated with High Gleason Grade and Predicts Worse Biochemical-Free Survival in Prostate Cancer

2006 ◽  
Vol 175 (4S) ◽  
pp. 260-260
Author(s):  
Rile Li ◽  
Hong Dai ◽  
Thomas M. Wheeler ◽  
Anna Frolov ◽  
Gustavo Ayala
Keyword(s):  
Prostate Cancer ◽  
Cyclin D1 ◽  
Gleason Grade ◽  
Free Survival ◽  
High Level
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