Recurrent skin infection associated with nasal carriage of Panton–Valentine leukocidin-positive methicillin-susceptible Staphylococcus aureus closely related to the EMRSA-15 clone

2016 ◽  
Vol 11 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Carla Vignaroli ◽  
Laura Di Sante ◽  
Paola Stano ◽  
Pietro E Varaldo ◽  
Alessandro Camporese
Keyword(s):  
Staphylococcus Aureus ◽  
Skin Infection ◽  
Nasal Carriage ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

scholarly journals Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection

2015 ◽  
Vol 11 (11) ◽  
pp. e1005292 ◽  
Author(s):  
Ching Wen Tseng ◽  
Juan Carlos Biancotti ◽  
Bethany L. Berg ◽  
David Gate ◽  
Stacey L. Kolar ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Skin Infection ◽  
Nsg Mice ◽  
And Staphylococcus Aureus ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin ◽  
Increased Susceptibility

Panton-Valentine leukocidin producing Staphylococcus aureus nasal carriage, in North-Lebanon

2013 ◽  
Vol 43 (9) ◽  
pp. 386-390 ◽  
Author(s):  
R. Beyrouthy ◽  
M. Hamze ◽  
S. Hleis ◽  
H. Mallat ◽  
F. Dabboussi
Keyword(s):  
Staphylococcus Aureus ◽  
Nasal Carriage ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

scholarly journals The Carriage Population of Staphylococcus aureus from Mali Is Composed of a Combination of Pandemic Clones and the Divergent Panton-Valentine Leukocidin-Positive Genotype ST152

2008 ◽  
Vol 190 (11) ◽  
pp. 3962-3968 ◽  
Author(s):  
Raymond Ruimy ◽  
Aminata Maiga ◽  
Laurence Armand-Lefevre ◽  
Ibrahim Maiga ◽  
Amadou Diallo ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Western Europe ◽  
Nasal Carriage ◽  
Invasive Disease ◽  
Asymptomatic Carriage ◽  
The Common ◽  
Global Population ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

ABSTRACT Staphylococcus aureus is an important human pathogen, but it appears more commonly in asymptomatic colonization of the nasopharynx than in cases of invasive disease. Evidence concerning the global population structure of S. aureus is limited by the overrepresentation in the multilocus sequence testing database of disease isolates recovered from Western Europe, the Americas, Australia, and Japan. We address this by presenting data from the S. aureus carriage population in Mali, the first detailed characterization of asymptomatic carriage from an African population. These data confirm the pandemic spread of many of the common S. aureus clones in the carriage population. We also note the high frequency (∼24%) of a single divergent genotype, sequence type 152 (ST152), which has not previously been recovered from nasal carriage isolates but corresponds to a sporadic Panton-Valentine leukocidin (PVL)-positive, community-acquired methicillin-resistant S. aureus clone noted mostly in Central Europe. We show that 100% of the ST152 isolates recovered from nasal carriage samples in Mali are PVL positive and discuss implications relating to the emergence and spread of this virulent genotype.

Staphylococcus aureus Nasal Carriage in Medical Students of Universiti Teknologi MARA

2017 ◽  
Vol 2 (1) ◽  
pp. 29 ◽  
Author(s):  
Zaini Mohd Zain ◽  
Muhammad Fikri Johari ◽  
Nurul Shahirah Mohd Husin ◽  
Nurul Syamimi Rozman ◽  
Athirah Ab Rashid ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Medical Students ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Nasal Carriage ◽  
Tissue Necrosis ◽  
Mannitol Salt Agar ◽  
Microbiological Techniques ◽  
Polymerase Chain ◽  
Low Prevalence ◽  
Panton Valentine Leukocidin

Introduction: To determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage and detection of S. aureus leukotoxins among medical students of Universiti Teknologi MARA. Methods: Both sides of the anterior nares of 136 volunteers, comprising 68 preclinical and 68 clinical medical students, were swabbed and immediately cultured onto mannitol salt agar for growth of S. aureus. Standard microbiological techniques were conducted to identify and confirm the S. aureus colonies and susceptibility test against oxacillin were conducted by using Kirby-Bauer method to determine their resistance to methicillin. Polymerase chain reaction was performed for detection of leukotoxins, i.e., Panton-Valentine Leukocidin (PVL) and -haemolysin genes. Results: Nineteen students (14%) consisting of 10 preclinical (14.7%) and 9 clinical (13.2%) were nasal carriers of S. aureus. However, none of the S. aureus isolates were MRSA. No PVL gene was detected but eight of them were positive for -haemolysin gene. Conclusion: There were no MRSA nasal carriers among the medical students, but a low prevalence of S. aureus nasal carriers was detected. These carriers do not pose as high risk because none of the strains of S. aureus possess both the -haemolysin toxin and the PVL toxin that are associated with tissue necrosis.

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