scholarly journals Evaluation of Analgesic Effect of Unani Pharmacopoeial Formulation Habb-E-Suranjan and Raughan-E-Suranjan in Wajaul Mafasil (Joints Pain) Patients: An Open Prospective Clinical Trial

2021 ◽  
Vol 11 (2-S) ◽  
pp. 44-49
Author(s):  
NOOR ZAHEER AHMED ◽  
KABIRUDDIN AHMAD ◽  
R EZHIL ◽  
NIGHAT ANJUM ◽  
ASIM ALI KHAN
Keyword(s):  
Joint Pain ◽  
Therapeutic Response ◽  
Conventional Medicine ◽  
Treatment Protocol ◽  
Institutional Ethics ◽  
Prior Approval ◽  
Laboratory Investigations ◽  
Present Trial ◽  
Pain Patients ◽  
Written Informed Consent

Wajaul Mafasil (joint pain) is the most prevalent and common cause of morbidity and disability not only in India but also throughout the world. In spite of various scientific developments in conventional medicine, there is no specific therapy or cure available for joints pain particularly when the disease has progressed to chronic stage. Therefore, it is the need of the hour to explore new formulations from herbal sources which are safe and effective. The present trial was undertaken to scientifically validate the Unani pharmacopoeial compound formulations of Habb-e-Suranjan and Raughan-e-Suranjan for its safety and efficacy in patients with joints pain. Patients with joint pain, who gave written informed consent, were recruited in the study from general OPD of RRIUM, Chennai with the prior approval of the Institutional Ethics Committee. 97 patients completed the study treatment. The treatment protocol was followed for 14 days and the clinical evaluation was done on seventh and fourteenth day of the treatment. At the end of fourteenth day intensity of individual parameters like joints pain, swelling, tenderness and restriction of movement showed statistically significant improvement (p<0.05). Overall therapeutic response of the treatment observed in this study was 100%. It was observed that 47.4% cases were completely relieved; 51.4% cases were relieved while 1.2% cases showed partial relief after the treatment. The laboratory investigations showed that the drugs used in the study were safe as evident by its maintenance. It may be concluded that Habb-e-Suranjan in combination with Raughan-e-Suranjan possesses significant analgesic property and may be a better option for the patients of joint pain. Keywords: Arthritis, Joints pain, Wajaul Mafasil, Habb-e-Suranjan, Raughan-e-Suranjan

scholarly journals Palindromic rheumatism - an unusual Presentation of rheumatoid arthritis

2013 ◽  
Vol 22 (1) ◽  
pp. 93-95
Author(s):  
Sarmistha Biswas ◽  
Anonnya Rahman ◽  
Partha Pratim Das ◽  
Md Enamul Karim ◽  
Abed Hussain Khan ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Rheumatoid Arthritis ◽  
Joint Pain ◽  
Unusual Presentation ◽  
Palindromic Rheumatism ◽  
Medical College ◽  
Laboratory Investigations

We have reported a 24 years old woman presenting with recurrent episodes of joint pain, weakness and fever for last one and half year. Each episode persists for 3/4 days and intervals between episodes are variable. Laboratory investigations showed positive RF and anti-CCP. Each episode remits spontaneously with some NSAIDs. The case high lights the need of accepting Palindromic presentation of early Rheumatoid arthritis and it is not very rare as we think. DOI: http://dx.doi.org/10.3329/jdmc.v22i1.15707 J Dhaka Medical College, Vol. 22, No. 1, April, 2013, Page 93-95

scholarly journals Low Level Laser Therapy for chronic knee joint pain patients

LASER THERAPY ◽  
2014 ◽  
Vol 23 (4) ◽  
pp. 273-277 ◽  
Author(s):  
Takashi Nakamura ◽  
Satoru Ebihara ◽  
Ikuko Ohkuni ◽  
Hideaki Izukura ◽  
Takashi Harada ◽  
...  
Keyword(s):  
Knee Joint ◽  
Laser Therapy ◽  
Joint Pain ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Pain Patients

Differences in sensory processing between chronic cervical zygapophysial joint pain patients with and without cervicogenic headache

Cephalalgia ◽  
2011 ◽  
Vol 31 (8) ◽  
pp. 953-963 ◽  
Author(s):  
Nicholas H L Chua ◽  
Hans A van Suijlekom ◽  
Kris C Vissers ◽  
Lars Arendt-Nielsen ◽  
Oliver H Wilder-Smith
Keyword(s):  
Joint Pain ◽  
Pain Threshold ◽  
Detection Threshold ◽  
Pressure Pain Threshold ◽  
Cervicogenic Headache ◽  
Pain Modulation ◽  
Zygapophysial Joint ◽  
Testing And Measurement ◽  
Threshold Testing ◽  
Pain Patients

Background: It is not known why some patients with underlying chronic nociceptive sources in the neck develop cervicogenic headache (CEH) and why others do not. This quantitative sensory testing (QST) study systematically explores the differences in sensory pain processing in 17 CEH patients with underlying chronic cervical zygapophysial joint pain compared to 10 patients with chronic cervical zygapophysial joint pain but without CEH. Methods: The QST protocol comprises pressure pain threshold testing, thermal detection threshold testing, electrical pain threshold testing and measurement of descending inhibitory modulation using the conditioned pain modulation (CPM) paradigm. Results: The main difference between patients with or without CEH was the lateralization of pressure hyperalgesia to the painful side of the head of CEH patients, accompanied by cold as well as warm relative hyperesthesia on the painful side of the head and neck. Discussion: From this hypothesis-generating study, our results suggest that rostral neuraxial spread of central sensitization, probably to the trigeminal spinal nucleus, plays a major role in the development of CEH.

Effectiveness of the use of an algorithm in the diagnostic approach of joint pain patients by primary care physicians

2020 ◽  
Vol 40 (11) ◽  
pp. 1857-1864
Author(s):  
D. G. Fernández-Ávila ◽  
M. X. Rojas ◽  
C. Ramírez ◽  
L. Rodelo ◽  
E. Soriano
Keyword(s):  
Primary Care ◽  
Joint Pain ◽  
Primary Care Physicians ◽  
Diagnostic Approach ◽  
Pain Patients

scholarly journals Fibrous Myopathy as a Complication of Repeated Intramuscular Injections for Chronic Headache

2006 ◽  
Vol 11 (4) ◽  
pp. 249-252 ◽  
Author(s):  
R Burnham ◽  
S McNeil ◽  
C Hegedus ◽  
DS Gray
Keyword(s):  
Magnetic Resonance Imaging ◽  
Joint Pain ◽  
Chronic Headache ◽  
Fibrous Tissue ◽  
Potential Complication ◽  
Resonance Imaging ◽  
Temporomandibular Joint Pain ◽  
Intramuscular Injections ◽  
Pain Patients

Two cases of fibrous myopathy associated with repeated, long-term intramuscular injections for treatment of chronic temporomandibular joint pain and chronic headache, respectively, are described. Both patients developed severe, function-limiting contractures in upper and lower extremity muscles used as injection sites. In one of the cases, the contractures were painful. Electrophysiological testing, magnetic resonance imaging and muscle biopsy results were all consistent with myopathy and replacement of skeletal muscle with noncontractile fibrous tissue. These cases are presented to increase awareness of fibrous myopathy and to promote surveillance for this serious potential complication of long-term intramuscular injections in chronic headache and other pain patients.

scholarly journals Kosovo’s Experience for Children with Feeding Difficulties after Cardiac Surgery for Congenital Heart Defect

2017 ◽  
Vol 5 (7) ◽  
pp. 920-924 ◽  
Author(s):  
Ramush Bejiqi ◽  
Ragip Retkoceri ◽  
Hana Bejiqi ◽  
Arlinda Maloku ◽  
Armend Vuciterna ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Heart Surgery ◽  
Chromosomal Abnormalities ◽  
Open Heart Surgery ◽  
Feeding Problems ◽  
Tertiary Referral Hospital ◽  
Feeding Disorder ◽  
Feeding Difficulties ◽  
Institutional Ethics ◽  
Prior Approval

BACKGROUND: A feeding disorder in infancy and during childhood is a complex condition involving different symptoms such as food refusal and faddiest, both leading to a decreased food intake.AIM: We aimed to assess the prevalence and predictor factors of feeding difficulties in children who underwent cardiac open heart surgery in neonatal period and infancy. We address selected nutritional and caloric requirements for children after cardiac surgery and explore nutritional interdependence with other system functions. METHODS: This was a retrospective study in a tertiary referral hospital, and prior approval from the institutional ethics committee was obtained. Information for 78 children (42 male and 36 female) was taken from patients charts. Data were analysed with descriptive statistics and logistic regression.RESULTS: From a cohort of analysed children with feeding problems we have occurred in 23% of such cases. At the time of the study, refusal to eat or poor appetite was reported as a significant problem in 19 children and subnormal height and weight were recorded in 11 children. Early neonatal intervention and reoperation were identified as risk factors for latter feeding difficulties or inadequate intake. Children with feeding problems also tended to eat less than children without feeding problems. There was a trend towards more feeding problems in patients with chromosomal abnormalities or other associated anomalies.CONCLUSION: Feeding disorder is often and a frequent long-term sequel in children after neonatal or early infancy heart surgery. Patients with chromosomal and associated anomalies who underwent multiple cardiac surgeries are at risk of developing feeding difficulties.

Adherence to treatment protocol in prehospital chest pain patients

Resuscitation ◽  
2008 ◽  
Vol 77 ◽  
pp. S1
Author(s):  
T. Staff ◽  
H.M.L. Lossius ◽  
P.A.S. Steen ◽  
L.W. Wik
Keyword(s):  
Chest Pain ◽  
Treatment Protocol ◽  
Adherence To Treatment ◽  
Pain Patients

scholarly journals EFFICACY AND SAFETY OF GABAPENTIN AND PREGABALIN IN CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY

2021 ◽  
pp. 130-132
Author(s):  
MANJUSHREE N ◽  
ANANYA CHAKRABORTY ◽  
SHASHIDHAR V
Keyword(s):  
Peripheral Neuropathy ◽  
Treatment Protocol ◽  
Research Centre ◽  
Efficacy And Safety ◽  
Medical Sciences ◽  
Institutional Ethics ◽  
Anti Cancer ◽  
Group A ◽  
Student’S T ◽  
Group B

Objectives: Chemotherapy-Induced Peripheral Neuropathy (CIPN) occurs as a common Adverse Drug Reaction (ADR) of anti-cancer drugs. The prevalence varies from 10% to 100%. To date, there is no standard effective treatment protocol for this condition. However, the neuro-modulators such as gabapentin and pregabalin are increasingly being used to treat CIPN. With this background this study was undertaken to compare the efficacy and safety of gabapentin and pregabalin in CIPN. Methods: This study was conducted in the department of medical oncology at Vydehi Institute of Medical Sciences and Research Centre, Bengaluru. It was initiated after the approval from Institutional Ethics Committee. After obtaining written informed consent, the participants were randomized into two groups. Group A received gabapentin, 300 mg orally and Group B received pregabalin 75 mg orally; twice daily for 8 weeks. They were followed up at 2, 4, and 8 weeks. The intensity and quality of pain were assessed by visual analog scale (VAS) and pain quality assessment scale (PQAS). Safety was assessed by reported ADR. Data were analyzed using Student’s t-test and Mann–Whitney U-test. p=0.05 or less was considered as statistically significant. Results: Reduction in VAS and PQAS scores at 8 weeks was statistically significant in each group (p<0.0001). The ADR common to both the groups was drowsiness and sedation. The prevalence of ADR was more in the gabapentin group. Conclusion: Both gabapentin and pregabalin have similar clinical efficacy in the treatment of CIPN. The prevalence of ADR was higher in gabapentin group compared to pregabalin group.

scholarly journals Study of antibiotic prescription pattern in PICU of a tertiary care hospital

2018 ◽  
Vol 7 (12) ◽  
pp. 2319
Author(s):  
Vivek Virbhan Bamel ◽  
Savita Ramesh Shahani
Keyword(s):  
Respiratory Tract ◽  
Antibiotic Prescription ◽  
Tertiary Care ◽  
Care Hospital ◽  
National Guidelines ◽  
Mortality And Morbidity ◽  
Institutional Ethics ◽  
Causes Of Mortality ◽  
Tract Infections ◽  
Written Informed Consent

Background: Infectious disease is one of the importance causes of mortality and morbidity in India, therefore pattern of use of antibiotics requires separate study as they differ from adult, Therefore the aim of our study is to observe the antibiotic prescription in the tertiary care hospital.Methods: A prospective observational study was carried out in the children admitted in PICU. The study was started after obtaining the approval from Institutional Ethics Committee. Written informed consent was obtained from a parent or legal guardian of participants.Results: There were 50 patients were enrolled. The maximum antibiotics were prescribed from cephalosporin class (42; 40.38%) which included ceftriaxone, cefixime, cefotaxim, cefpodoxime. The majority of cephalosporins were prescribed in miscellaneous cases followed by respiratory tract infections, gastrointestinal tract, Central nervous tract infections and nil in CVS cases, secondly higher number of antibiotics prescribed was metronidazole and from Aminopenicillin class which includes amoxiclav and ampicillin and another beta lactamase which includes ureidopenicilin and carbepenem. The majority of aminopenicillin were prescribed in miscellaneous group infections followed by respiratory tract infections.Conclusions: From this study, it can conclude that commonly antibiotic were from 3rd generation cephalosporins followed by metronidazole and other β lactamase inhibitor and all of the antibiotics were prescribed as per the national guidelines.

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