scholarly journals Analysis of the prevalence and severity of clinical manifestations of papillomavirus infection in HIV-infected women of childbearing age

2021 ◽  
Vol 13 (1) ◽  
pp. 37-44
Author(s):  
M. V. Radzikhovskaya ◽  
O. S. Anisimova ◽  
H. D. Magadeev ◽  
M. G. Moskvicheva ◽  
L. F. Telesheva ◽  
...  
Keyword(s):  
Hpv Vaccination ◽  
Clinical Manifestations ◽  
Statistical Processing ◽  
Carcinogenic Risk ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Hiv Viral Load ◽  
High Detection Rate ◽  
Papillomavirus Infection ◽  
Indirect Relationship

Objective: to determine the prevalence and severity of clinical and cytological manifestations of papillomavirus infection in HIV-infected women of childbearing age in relation to immunological and virological parameters.Materials and methods. Statistical data were obtained through direct randomised inclusion of 182 HIV-infected women of fertile age who were being followed up at the AIDS Centre during their initial gynaecological examinations. Statistical processing of the findings was carried out using IBM SPSS Statistics software.Results and discussion. The results of the study showed a high detection rate of chronic papillomavirus infection of high carcinogenic risk (HPV HRS) among HIV-infected women, which is a prognostically unfavorable factor for the development of pathological changes in the cervix and was confirmed in a study by extended colposcopy. It was found that the concentration of HPV VKR increases against the background of a decrease in the immune status, and there is an indirect relationship between the level of HIV viral load and the concentration of HPV VKR.Conclusion. The feasibility of HPV vaccination among HIV-infected girls and women aged 9–45 has been demonstrated.

Papillomavirus infection and reproduction

2020 ◽  
Vol 75 (3) ◽  
pp. 189-195
Author(s):  
Vladislav I. Krasnopolsky ◽  
Nina V. Zarochentseva ◽  
Ksenia V. Krasnopolskaya ◽  
Yulia N. Bashankaeva ◽  
Varvara S. Kuzmicheva
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccination ◽  
Carcinogenic Risk ◽  
Human Papillomaviruses ◽  
World Health ◽  
Sexually Transmitted ◽  
Associated Diseases ◽  
Trophoblastic Cells ◽  
Papillomavirus Infection ◽  
Health Organization

The purpose of the review a synthesis of research data on the role of human papillomavirus infection in the reproductive health of women and men. Key Points. Human papillomavirus (HPV) is one of the most common sexually transmitted viruses worldwide. According to the World Health Organization, HPV is the main cause of the development of HPV-associated diseases among both women and men. Viruses are subdivided into HPV with low carcinogenic risk, which cause benign warts, and HPV with high carcinogenic risk, which cause cancer. Different types of human papillomaviruses depending on their characteristic tropism, are divided into skin and mucous types. Viral infection in men leads to a decrease in the quality of sperm (for example, asthenozoospermia) due to apoptosis in sperm cells and due to the development of antisperm immunity. A negative viral effect on the fertility of women is manifested in an increase in the frequency of spontaneous miscarriages and a premature rupture of the amniotic membranes during pregnancy. There is evidence that HPV decreases the number of trophoblastic cells and abnormal trophoblastic-endometrial adhesion is also observed. In trophoblastic cells transfected with high-risk HPV, the level of apoptosis increases. HPV vaccination is safe, and the results show not only protection against HPV-associated diseases in women and men, but also a reduction of gestational complications, reduced preterm birth rates and the protection of newborns from infection.

scholarly journals Efficacy of acupuncture for melasma: a protocol of systematic review and meta-analysis

2021 ◽  
Author(s):  
Liheng Tang ◽  
◽  
Jin Xian ◽  
Ye Zhang ◽  
Changyun Zhang ◽  
...  
Keyword(s):  
Treatment Condition ◽  
Conventional Treatment ◽  
Meta Analysis ◽  
Clinical Manifestations ◽  
Asian Women ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Topical Drugs ◽  
Chemical Peeling ◽  
Review Question

Review question / Objective: How effective is acupuncture in treating melasma compared to conventional treatment？ Condition being studied: Melasma is a common acquired hyperpigmentation of the skin. The clinical manifestations are light brown or dark brown patches symmetrically distributed on the cheeks, forehead and mandibular with different shades and unclear borders. Melasma particularly affects women during menstruation, especially in thirties and forties Asian women. The incidence of Asian women of childbearing age is as high as 30%. Current treatments for melasma include topical drugs, chemical peeling agents, laser and light treatments, and systemic drugs. Despite the strong demand for treatment, the treatment of melasma is still very challenging, the results are inconsistent, and the recurrence rate is almost constant.

scholarly journals ОПТИМІЗАЦІЯ ЛІКУВАННЯ ЖІНОК З ХРОНІЧНИМ ЕНДОМЕТРИТОМ ЯК РЕЗЕРВ ПІДВИЩЕННЯ ФЕРТИЛЬНОСТІ

World Science ◽  
2018 ◽  
Vol 1 (10(38)) ◽  
pp. 28-32
Author(s):  
Донська Ю. В. ◽  
Лоскутова Т. О. ◽  
Сімонова Н. В. ◽  
Петулько А. П.
Keyword(s):  
Menstrual Cycle ◽  
Reproductive Potential ◽  
Clinical Manifestations ◽  
Reproductive Function ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Demographic Situation ◽  
Chronic Endometritis ◽  
The Creation

The worsening demographic situation encourages the search for new reserves to improve reproductive potential. The maximum incidence of chronic endometritis (97.6%) is 26-35 years old - the most important in the implementation of reproductive function. The lack of a single concept for the pathogenesis of HE, the purge of clinical manifestations impedes the creation of well-grounded therapy in women of childbearing age. The aim of the study was to increase the effectiveness of treatment of patients with confirmed chronic endometritis in order to restore fertility. It is proved that the use of the scheme, which includes antibacterial (doxycycline 100 mg orally 2 times a day and metronidazole 500 mg 2 times a day for 14 days in one menstrual cycle) and cyclic progestogen (didrogesterone at a dose of 20 mg per day with 15 to 25 days of the menstrual cycle - within three months), therapy can restore the morpho-functional endometrium potential by 88% compared with the initial rates.

scholarly journals MEDICAL AND SOCIAL ASPECTS OF INDUCED ABORTION IN THE REPUBLIC OF DAGESTAN

2018 ◽  
Vol 13 (2) ◽  
pp. 217-224
Author(s):  
Aziza G. Gasangadzhieva ◽  
Patimat I. Gabibova ◽  
Gyulnara M. Nakhibasheva ◽  
Elmira M. Medzhidov ◽  
Zaira E. Abdullaeva ◽  
...  
Keyword(s):  
Rural Areas ◽  
Inflammatory Diseases ◽  
Statistical Processing ◽  
Social Aspects ◽  
Spontaneous Abortions ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Average Percentage ◽  
Perinatal Pathology ◽  
The Republic

Aim. The aim of the research is to consider the medical and social aspects of artificially terminating pregnancy in the Republic of Dagestan. Material and methods. To achieve this goal, we have created a database of the cases of artificial abortion in the Republic of Dagestan. Statistical processing of the results of the study was carried out using software packages like STATISTICA and Excel. Results. The total number of abortions for the study period was 157526 cases, of which 26% of cases were spontaneous abortions, 8.9% of cases were abortions for medical reasons. During the period under review, there was an increase in the number of spontaneous abortions and abortions due to medical indications by 170% and 108.6%, respectively. There is the prevalence of abortions of the pregnancy of up to 12 weekperiod, including mini-abortions, the average percentage of the total number of abortions for the study period was 90%. In the Republic of Dagestan, the average annual intensive standardized abortion rate was 14.67 cases per 1,000 women of childbearing age women of childbearing age (WCA). And among the urban population, this number is higher, and amounted to 25.57 ‰ against 6.25 ‰ in rural areas. The highest values of the average long-term intensive frequency of abortions are observed in the cities of Kizilyurt, Derbent, Makhachkala, Kaspiisk; in the countrysides: Dakhadayevsky, Tarumovsky, Laksky and Babaurtovsky districts. Conclusion. The problem of abortion, despite the steady tendency to reduce their number, still needs to be solved because it is the leading cause of maternal death in Russia, inflammatory diseases of the genitals, infertility, and it also adversely affects the course of subsequent pregnancies and births, increasing the frequency miscarriage, maternal and perinatal pathology.

scholarly journals Intention to Pay for HPV Vaccination among Women of Childbearing Age in Vietnam

2020 ◽  
Vol 17 (9) ◽  
pp. 3144 ◽  
Author(s):  
Xuan Thi Thanh Le ◽  
Phuong Thi Ngoc Nguyen ◽  
Toan Thi Thanh Do ◽  
Thang Huu Nguyen ◽  
Huong Thi Le ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Rural Areas ◽  
Hpv Vaccination ◽  
Cross Sectional Study ◽  
Rural District ◽  
Health Concern ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Cross Sectional ◽  
Current Price

The intention to pay for human papillomavirus (HPV) vaccination among women of childbearing age in Vietnam, where cervical cancer remains a significant public health concern, has been mostly lacking. To examine this issue, we conducted a cross-sectional study of 807 pregnant women in an urban and a rural district (Dong Da and Ba Vi) of Hanoi, Vietnam. The vast percentage of our respondents expressed a firm intention to vaccinate, especially women in rural areas (over 90.0%). However, on being informed of the current price of the HPV vaccine, their intention to vaccinate dropped to about one-fifth of overall respondents, i.e., only 4.4% of women in rural areas. It was also observed that the initial intention to get the HPV vaccination among women in the rural district was about ten times higher than that of women living in the metropolitan district. Those participants who had greater knowledge of cervical cancer and HPV vaccinations also had a significantly higher intention to vaccinate. Our findings underscore the need to develop a well-designed vaccination program in Vietnam and other countries in a similar situation to increase the adoption of HPV vaccination.

scholarly journals Modern considerations on the predisposing factors in the etiopathogenesis of systemic lupus erythematosus

2021 ◽  
Vol 68 (1) ◽  
pp. 22-30
Author(s):  
Ionica-Mariana Radulescu ◽  
◽  
Mihail Alecu ◽  
Laura Ion ◽  
Cosmin Moldovan ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Autoimmune Disease ◽  
Lupus Erythematosus ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Published Data ◽  
Women Of Childbearing Age ◽  
Childbearing Age ◽  
Systemic Lupus ◽  
Trigger Factors

Lupus erythematosus is an autoimmune disease with severe skin involvement and/or multisystemic implications characterized by the development of autoantibodies and immune complexes that, in turn, cause inflammation, tissue damage and a variety of clinical manifestations. The etiopathogeny of lupus erythematosus is very complex and still incompletely discovered. The onset of this disease or the episodes of exacerbation involves various factors: genetic, immune, hormonal, environmental but many more are still under research. There is strong evidence to back up the theory of an autoimmune disease, even though the precise mechanism is yet to be discovered. Apart from a preexisting background predisposing to lupus, certain triggers are required to act in a synergic way to determine the onset of the clinical signs. Studies show that it is 10-15 times more common in women of childbearing age than men, with a higher incidence amongst Afro-American population compared to Caucasians. The aim of this article is to shed some light on the most important determining and trigger factors involved in systemic lupus erythematosus by reviewing the most recent published data.

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