scholarly journals Convexity meningioma associated with depression: A case report

2014 ◽  
Vol 142 (9-10) ◽  
pp. 586-588 ◽  
Author(s):  
Nenad Zivkovic ◽  
Marko Markovic ◽  
Milan Spaic
Keyword(s):  
Case Report ◽  
Major Depression ◽  
Psychiatric Symptoms ◽  
Late Onset ◽  
Depression Symptoms ◽  
Total Resection ◽  
Long Time ◽  
Fibroblastic Meningioma ◽  
Slow Growing ◽  
The Brain

Introduction. Meningiomas are slow growing, extra-axial lesions, and can be neurologically silent for a long time and present only with depression. Case Outline. A 65-year-old woman developed major depression and was treated with antidepressants for two years. Depression failed to respond to drug treatment and there was no improvement. Two months before admission to hospital, due to the onset of epilepsy attack the patient underwent reinvestigation, and a large temporal convexity meningioma, which corresponded in position to the original electroencephalography focus, was diagnosed using the computer topography of the brain. The patient underwent osteoplastic craniotomy, and a left fronto-temporal convexity meningioma of 5 cm in diameter was completely removed with its attachment to the dura. Histological examination confirmed a fibroblastic meningioma. Conclusion. Total resection of convexity meningioma and decompression of the brain tissue in the region of limbic pathways that are involved, may contribute to a complete remission of depression symptoms. This case also illustrates the need for a prompt neuroimaging of the brain when patients present any atypical psychiatric symptoms, with late onset (>50 years old) of the first depressive episode or fast changes of the mental state.

scholarly journals Catatonia Associated With Late Paraphrenia Successfully Treated With Lithium: A Case Report

2020 ◽  
Author(s):  
Hiroko Sugawara ◽  
Junpei Takamatsu ◽  
Mamoru Hashimoto ◽  
Manabu Ikeda
Keyword(s):  
Case Report ◽  
Mood Disorders ◽  
Electroconvulsive Therapy ◽  
Late Onset ◽  
Treatment Strategies ◽  
Psychotic Symptoms ◽  
Case Presentation ◽  
Limited Efficacy ◽  
Cumulative Evidence ◽  
The Brain

Abstract Background: Catatonia is a psychomotor syndrome that presents various symptoms ranging from stupor to agitation, with prominent disturbances of volition. Its pathogenesis is poorly understood. Benzodiazepines and electroconvulsive therapy (ECT) are safe and effective standard treatments for catatonia; however, alternative treatment strategies have not been established in cases where these treatments are either ineffective or unavailable. Here, we report a case of catatonia associated with late paraphrenia classified as very-late-onset schizophrenia-like psychosis, which was successfully treated with lithium. Case presentation: A 66-year-old single man with hearing impairment developed hallucination and delusions and presented with catatonic stupor after a fall. He initially responded to benzodiazepine therapy; however, his psychotic symptoms became clinically evident and benzodiazepine provided limited efficacy. Blonanserin was ineffective, and ECT was unavailable. His catatonic and psychotic symptoms were finally relieved by lithium monotherapy.Conclusions: Catatonic symptoms are common in patients with mood disorders, suggesting that lithium may be effective in these cases. Moreover, lithium may be effective for both catatonic and psychotic symptoms, as it normalizes imbalances of excitatory and inhibitory systems in the brain, which underlies major psychosis. Cumulative evidence from further cases is needed to validate our findings.

Late-Onset Huntington's Disease: A Geriatric Psychiatry Perspective

1996 ◽  
Vol 9 (1) ◽  
pp. 26-29 ◽  
Author(s):  
Kenneth I. Shulman ◽  
Anne Lennox ◽  
Harry Karlinsky
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Elderly Patients ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Psychiatric Symptoms ◽  
Late Onset ◽  
Clinical Aspects ◽  
Illustrative Case ◽  
Wide Range

Late-onset Huntington's disease is more common than has been generally appreciated and is associated with a wide range of psychiatric symptoms and syndromes. Geriatric psychiatrists have an important role to play in establishing the diagnosis and providing guidance to elderly patients and their families as they struggle with difficult management decisions. An illustrative case report and selective literature review are presented that highlight the genetic and clinical aspects of the condition.

scholarly journals Tuberculoid Granuloma in the Brainstem: Case Report

2016 ◽  
Vol 38 (01) ◽  
pp. 064-067
Author(s):  
Tobias Ludwig ◽  
Luiz Rogerio ◽  
Marcelo Reis ◽  
Leandro de Almeida ◽  
Gabriel Frizzon ◽  
...  
Keyword(s):  
Case Report ◽  
Resonance Imaging ◽  
Total Resection ◽  
Present Case Report ◽  
Immunosuppressed Patients ◽  
The Central Nervous System ◽  
Cerebral Parenchyma ◽  
Magnetic Resonance Imaging Mri ◽  
Histopathologic Analysis ◽  
The Brain

AbstractMeningitis or meningoencephalitis are the most common presentations of Koch bacilli infection on the central nervous system (CNS), especially in immunosuppressed patients, in whom the bacilli normally reaches the meninges and the cerebral parenchyma.. A least common pathological presentation is the tumoral growth pattern disease known as tuberculoma. This pathological entity is more common in the cerebral hemispheres and is rarely located in the brainstem. The present case report describes a case of a 55-year-old patient under regular antiretroviral therapy who was hospitalized with signs of brainstem and cerebellar disturbances. Computed tomography (CT) and magnetic resonance imaging (MRI) of the brain showed an exophytic lesion in the dorsal region of the pons. The patient underwent total resection of the lesion and the histopathologic analysis was consistent with a tuberculoma.

Endoscope-Controlled Microneurosurgery to Treat Middle Fossa Epidermoid Cysts: Technical Case Report

2008 ◽  
Vol 62 (suppl_1) ◽  
pp. ONSE105-ONSE107 ◽  
Author(s):  
Felipe P. Trivelato ◽  
Alexandre V. Giannetti
Keyword(s):  
Case Report ◽  
Functional Outcomes ◽  
Skin Incision ◽  
Wide Resection ◽  
Alternative Technique ◽  
Middle Fossa ◽  
Total Resection ◽  
Epidermoid Cysts ◽  
The Brain ◽  
Neurovascular Structures

Abstract Objective: To present an alternative technique of endoscope-controlled microneurosurgery for the treatment of middle fossa epidermoid cysts. Methods: The three operations described were performed through an approximately 2-cm diameter temporal craniotomy after a straight skin incision was made. Resection was then performed under the magnification of a 30-degree rigid endoscope, which mandated the use of exclusively conventional microsurgical instruments. Results: Total resection was accomplished in all three patients with large middle fossa epidermoid cysts through a small temporal corticectomy, without damage to neurovascular structures. Conclusion: This procedure allowed the association of a smaller craniotomy, better cosmetic results, and minor retraction of the brain to wide resection of the tumor and satisfactory functional outcomes.

scholarly journals Schistosomiasis mansoni presenting as a cerebellar tumor: case report

2007 ◽  
Vol 65 (3b) ◽  
pp. 845-847 ◽  
Author(s):  
Joacil Carlos da Silva ◽  
Frederico de Melo Tavares de Lima ◽  
Cláudio Henrique Vidal ◽  
Hildo Cirne Rocha de Azevedo Filho
Keyword(s):  
Case Report ◽  
Schistosoma Mansoni ◽  
Microscopic Examination ◽  
Cerebellar Tumor ◽  
Total Resection ◽  
Male Predominance ◽  
Schistosomiasis Mansoni ◽  
Radiological Aspect ◽  
Cerebellar Mass ◽  
The Brain

The Manson's schistosomiasis tumoral form rarely affects the brain. There are only 12 cases prior related with a mean age of 25 years and a male predominance. We describe a 16-year-old Brazilian Northeastern boy with a cerebellar mass lesion. The radiological aspect was considered compatible with glioma and a gross total resection was performed. Microscopic examination disclosed intraparenchymal granulomas surrounding Schistosoma mansoni eggs. The case is compared with the literature findings and some peculiar aspects of this trematode infection are reviewed.

scholarly journals A giant solid cystic inferior fourth ventricle subependymoma – Case report and literature review

2016 ◽  
Vol 30 (4) ◽  
pp. 455-460
Author(s):  
A. Giovani ◽  
Narcisa Bucur ◽  
Ana Gheorghiu ◽  
Lena Papadopol ◽  
R.M. Gorgan
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Posterior Fossa ◽  
Fourth Ventricle ◽  
Precursor Cells ◽  
Benign Tumors ◽  
Total Resection ◽  
Who Grade ◽  
Slow Growing ◽  
Glial Precursor

Abstract Subependymomas are a rare subtype of ependymomas, slow growing WHO grade I tumors that develop either intracranial from the subependymal glial precursor cells layer of the ventricles or intramedullary. These tumors originate in the undifferentiated Subependymal layer of cells that can become either ependymocytes or astrocytes. Most of the subependymomas are located inside the fourth ventricle (50-60%). We reviewed the case of a 40 years old woman with a giant solid cystic fourth ventricle ependymoma. The patient underwent total resection of the tumor through a subociipital transvermian approach. We discussed the characteristics of these benign tumors and reviewed the literature on this subject and concluded that total resection is the treatment of choice for symptomatic Subependymomas localized in posterior fossa.

scholarly journals Atypical presentation of late-onset Sandhoff disease : A case report

2021 ◽  
Vol 74 (11-12) ◽  
pp. 425-429
Author(s):  
András Salamon ◽  
László Szpisjak ◽  
Dénes Zádori ◽  
István Lénárt ◽  
Zoltán Maróti ◽  
...  
Keyword(s):  
Case Report ◽  
Lower Limb ◽  
Psychiatric Symptoms ◽  
Age Of Onset ◽  
Late Onset ◽  
Brain Mri ◽  
Residual Activity ◽  
Sandhoff Disease ◽  
Limb Weakness ◽  
Hexb Gene

Sandhoff disease is a rare type of hereditary (autosomal recessive) GM2-gangliosidosis, which is caused by mutation of the HEXB gene. Disruption of the β subunit of the hexosaminidase (Hex) enzyme affects the function of both the Hex-A and Hex-B isoforms. The severity and the age of onset of the disease (infantile or classic; juvenile; adult) depends on the residual activity of the enzyme. The late-onset form is characterized by diverse symptomatology, comprising motor neuron disease, ataxia, tremor, dystonia, psychiatric symptoms and neuropathy. A 36-year-old female patient has been presenting progressive, symmetrical lower limb weakness for 9 years. Detailed neurological examination revealed mild symmetrical weakness in the hip flexors without the involvement of other muscle groups. The patellar reflex was decreased on both sides. Laboratory tests showed no relevant alteration and routine electroencephalography and brain MRI were normal. Nerve conduction studies and electromyography revealed alterations corresponding to sensory neuropathy. Muscle biopsy demonstrated signs of mild neurogenic lesion. Her younger brother (32-year-old) was observed with similar symptoms. Detailed genetic study detected a known pathogenic missense mutation and a 15,088 base pair long known pathogenic deletion in the HEXB gene (NM_000521.4:c.1417G>A; NM_000521:c.-376-5836_669+1473del; double heterozygous state). Segregation analysis and hexosaminidase enzyme assay of the family further confirmed the diagnosis of late-onset Sandhoff disease. The purpose of this case report is to draw attention to the significance of late-onset Sandhoff disease amongst disorders presenting with proximal predominant symmetric lower limb muscle weakness in adulthood.

Frontal meningioma and bipolar disorder: Etiopathogenic link or co-morbidity? A case report

2017 ◽  
Vol 41 (S1) ◽  
pp. S678-S678
Author(s):  
I. Chaari ◽  
H. Ben Ammar ◽  
R. Nefzi ◽  
N. Mhedhbi ◽  
E. Khelifa ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Case Report ◽  
Suicide Attempts ◽  
Psychiatric Symptoms ◽  
Late Onset ◽  
Manic Episode ◽  
Atypical Symptoms ◽  
Co Morbidity ◽  
Major Depressive Episodes ◽  
Depressive Episodes

IntroductionFrontal meningiomas are benign brain tumours known for their late onset. They may be presented by only psychiatric symptoms. Thus, the diagnosis at early stages can be missed or overlooked until the tumour causes neurological deficit.Case reportWe report the case of a 61-year-old man, receiving a treatment and a follow-up for bipolar disorder for 11 years. He has history of 3 major depressive episodes, 2 suicide attempts and a manic episode. The symptoms were initially well controlled by medication. Since 6 months, the patient started to experience atypical symptoms: he had presented disinhibited and aggressive behaviour, psychomotor instability, pyromania and self-neglect. The patient did not respond to treatment despite repeated adjustments. A frontal syndrome was suspected. Cerebral CT scan revealed an unexpected mass measuring 6.8 cm × 5.6 cm at the right frontal area, suggestive of a giant meningioma (Fig 1).ConclusionsGenerally, once diagnosed, psychiatric disorders are rarely revised. Consequently, “silent” tumours such as frontal meningiomas can be overlooked. Neuroimaging should be considered in case of new-onset psychiatric symptoms, atypical or change in clinical presentation.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Hemorrhagic Epidermoid Cyst in Cerebellar Vermis: Case Report and Review of the Literature

2021 ◽  
Vol 82 (01) ◽  
pp. e6-e10
Author(s):  
Ján Kozák ◽  
Jozef Šurkala ◽  
Martin Novotný ◽  
Marián Švajdler
Keyword(s):  
Case Report ◽  
Epidermoid Cyst ◽  
Cerebellopontine Angle ◽  
Review Of The Literature ◽  
Basal Surface ◽  
Parasellar Region ◽  
Benign Nature ◽  
Intracranial Epidermoid ◽  
Slow Growing ◽  
The Brain

AbstractIntracranial epidermoid cysts are slow growing congenital avascular neoplasms that spread across the basal surface of the brain. They most commonly occur in the paramedial region in the cerebellopontine angle and the parasellar region. Despite its generally benign nature, sporadically they can be accompanied with hemorrhage or very rarely undergo malignant transformation. The authors present a case report of a patient with a hemorrhagic vermian epidermoid cyst and a review of all published similar cases.

scholarly journals Schizencephaly Associated with Polymicrogirya – Cause for Late-Onset Epileptic Seizures in Adult. A Case Report.

2016 ◽  
Vol 22 (4) ◽  
pp. 228-231
Author(s):  
Mihaela Lungu ◽  
Aurelia Romila ◽  
L.T. Hangan ◽  
B.M. Caraban
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Late Onset ◽  
Epileptic Seizures ◽  
Psychological Trauma ◽  
Rapid Onset ◽  
Neurological Illness ◽  
History Of ◽  
Convulsive Seizures ◽  
The Brain

Abstract The article presents the case of a 61-year old female patient, with no history of neurological illness, who presents a rapid onset of two convulsive seizures, triggered by a psychological trauma. The first convulsive seizure is repeated within 24 hours. The general, as well as the neurological clinical examination have not found any pathological signs. MRI scanning of the brain pointed to right-parietal schizencephaly, associated with polymicrogyria, the believed causes of the epileptic seizures.

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