scholarly journals Quality of life in patients with laryngeal cancer before and after surgery

2019 ◽  
Vol 147 (11-12) ◽  
pp. 713-717
Author(s):  
Tomasz Zatoński ◽  
Mateusz Kolator

Introduction/Objective. Assessment of the Quality-of-life questionnaires was filled out before and after surgery by patients with laryngeal cancer hospitalized in the Otolaryngology, Head and Neck Surgery Department, qualified for surgical treatment. Methods. Fifty-four patients with laryngeal cancer in T3 and T4 stages who were qualified for total laryngectomy were asked to fill out the EORTC QLQ-30 and H&N30 modules before and a few years after surgical treatment. Results. The quality of life of the hospitalized patients increased after surgery. The level of pain after surgery decreased and was statistically significant (p = 0.025). In the study group, 90.6% of patients survived five years after surgery. Conclusion. The quality of life in patients with laryngeal cancer improved in the domain of pain. Further research should be conducted on a larger group of patients. Future results could provide useful material for analysis regarding the benefits for the patient that may be relevant to a decision to consent to the proposed treatment and the choice of its type.

2015 ◽  
Vol 8 (6) ◽  
pp. 203 ◽  
Author(s):  
Maria Arvaniti ◽  
Nikolaos Danias ◽  
Eleni Theodosopoulou ◽  
Vassilis Smyrniotis ◽  
M. Karaoglou ◽  
...  

<p><strong>INTRODUCTION: </strong>The treatment of pancreatic cancer is a complex problem, due to late diagnosis, the need for specialized surgical treatment, the large number of relapses and poor survival.</p><p><strong>OBJECTIVE: </strong>To evaluate the quality of life of patients with periampulary pancreatic cancer before and after pancreatoduodenectomy (PD).</p><p><strong>MATERIAL &amp; METHOD: </strong>The sample was collected in the "Attikon" University General Hospital (Chaidari)<strong>.</strong> It consists of 20 subjects with a mean age of 65.9 years (SD = 10,2 years). For the quality of life measurement, we used the (EORTC) QLQ-C30 version 3.0., as well as the EORTC QOL-PAN26.</p><p><strong>RESULTS: </strong>From<strong> </strong>the sample of 20 patients who participated, full data were collected for 18 of them during the first month, 17 during the third month and 16 during the sixth month.</p><p>Regarding symptoms, as they were recorded with the QLQ-30 questionnaire, there was a significant increase of fatigue, a significant reduction of pain and constipation, while economic difficulties increased.  As for the mean and median values for the dimensions of the PAN-26 questionnaire during monitoring, there was a significant decrease in pancreatic and liver pain symptoms during follow-up, while the gastrointestinal symptoms increased in frequency. In addition, the body image and sexuality worsened.</p><p><strong>CONCLUSIONS: </strong>The surgical treatment of pancreatic cancer with pancreatoduodenectomy (PD), according to the early survey data using the (EORTC) QLQ-C30 version3.0, and the EORTC QOL-PAN26 questionnaires, seems to have a favorable impact on quality of life, as evidenced by the improvement of most parameters evaluated during the study period.</p>


Author(s):  
Grażyna Bączyk ◽  
Urszula Kwapisz ◽  
Katarzyna Karpińska

Introduction. The assessment of the quality of life in cancer patients requires a multidisciplinary approach and an evaluation of emotional, social and physical conditions. Objectives. The aim of the study was to analyze the quality of life patients after surgical treatment of laryngeal cancer but before the next stage of therapy, i.e. radiotherapy.Material and Methods. The study group comprised 60 patients aged 44–82 years, with laryngeal cancer treated at the Radiotherapy Wards of Wielkopolskie Centrum Onkologii, Poznań, Poland. The Polish versions of the QLQ C-30 and the cancer‑specific EORTC QLQ H&N35 questionnaires were used.Results. Mean score for the general health status (QLQ C-30) was 56.81. Mean values for the physical, role, cognitive, social and emotional functioning were 81.11, 80.83, 75.28, 70.00 and 54.72, respectively. The following constituted the main problems for laryngectomees: difficulty gaining weight (75.00), necessity to take nutritional supplements (58.33), sense of smell and taste problems (57.78), weight loss (56.67), articulation problems (56.67). A statistically significant difference (p = 0.002) was observed with regard to emotional functioning, with mean values of 28.83 and 60.51 for women and men, respectively. Also, a statistically significant difference (p = 0.01) was observed with regard to social functioning, with mean values of 45.53 and 75.51 for women and men, respectively. Conclusions. There exists a definite need to investigate the quality of life by means of patient self‑evaluation of the symptoms in order to monitor patient status and establish an individual therapeutic, care and psychological approach.


2020 ◽  
Vol 77 (9) ◽  
pp. 908-916
Author(s):  
Sanja Kostic ◽  
Zafir Murtezani ◽  
Zoran Andric ◽  
Nebojsa Ivanovic ◽  
Zoran Kozomara ◽  
...  

Background/Aim. Breast cancer comprises about 25% of all female cancers, and its incidence is increasing. New diagnostic procedures and therapeutic modalities have increased treatment success rates as well as patient survival. The goal of contemporary treatment is not only patient survival, but also a better quality of life (QoL). The objective of this study was to assess the effect of age at diagnosis on the QoL of patients with breast cancer before and after surgery. Methods. We analyzed QoL in 170 female patients (43 patients < 50 and 127 patients ? 50 years) diagnosed with breast cancer (I and II stage) a month before and after surgical treatment, using the European Organisation for Research and Treatment of Cancer (EORTC QLQ-C30) questionnaire and specific version for breast cancer patients (EORTC QLQ-BR23). Results. The QLQ-C30 questionnaire showed that surgical treatment significantly decreased all domains of the patients? QoL in both age groups. Agerelated differences were present in sexual functioning and pleasure independently of surgical treatment, with higher scores in the group of younger women. The analysis of data obtained using the QLQ-BR23 questionnaire revealed a lower QoL after surgical treatment in almost all dimensions regardless of patients? age. Conclusion. The results of our study pointed out statistically significant differences in the QoL domains of sexual functioning, and sexual enjoyment between women in both age groups independently of surgical treatment. The QoL was better in the younger age group. Surgical breast cancer treatment negatively affected patients QoL independently of age.


2019 ◽  
Vol 6 (3) ◽  
pp. 108-114 ◽  
Author(s):  
A. D. Sergienko ◽  
V. E. Khoronenko ◽  
E. V. Gameeva ◽  
A. B. Ryabov ◽  
V. M. Khomyakov

Purpose of the study. To determine the effect of nutritional deficiency and nutritional therapy on the quality of life of patients with gastric cancer at the stage of surgical treatment. Patients and methods. In Thoracoabdominal Department of P. Herzen Moscow Oncology Research Institute within 2017– 2019 the quality of life at the stage of surgical treatment of gastric malignant neoplasms was evaluated in 62 patients (36 men and 26 women) aged 34 to 79 years (mean age 61.9 ± 9.55). At the outpatient stage, patients were divided into 2 groups: in the 1st (main) group, patients received nutritive support with specialized mixtures for 10 days before hospitalization, in the 2nd (control) group, patients were asked to follow a high-protein diet without adding specialized mixtures. The quality of life assessment was carried out on the basis of the EORTC-QLQ-C30 Questionnaire, which patients received on the day of hospitalization. Patients repeatedly filled in EORTC-QLQ-C30 Questionnaire before discharge from the hospital, which allowed to assess the dynamics of the quality of life indicators of the studied patients. The study groups were comparable in social and medical indicators. Results. The analysis of the survey results showed that the “general state of health” in the studied groups at the stage of hospitalization is estimated �bove average. Also, in both groups there is a positive dynamics in the values of the above indicator before discharge. Patients of the 1st group who received specialized nutritional mixtures, developed the statistical significance of the differences in the assessment of the quality of life upon admission and before discharge. Thus, it can be argued that nutritional therapy had a significant positive impact on the quality of life in terms of “general health”, in contrast to the control group of patients who did not receive specialized nutritional therapy. There was a general tendency toward an increase in the quality of life indicators at admission and before discharge on all scores of the questionnaire in groups. Thisis a positive assessment by patients of their condition after providing them with medical services. In this case, the discomfort from the symptoms accompanying the disease is reduced, which is confirmed by the scoring results. Statistically significant differences in the assessment of symptoms occur in the study group. Patients having received nutritional therapy noted a decrease in pain, an improvement in the processes of assimilation of food, as well as an improvement in well-being, physical condition, an increase in general tone and energy, a surge of strength and a sense of vitality. In “decreased appetite”score the indices of patients in the main group decreased by more than 3 times, i. e. their appetite improved significantly under treatment. Improving appetite in patients of the main group led to an improvement in the functioning of the gastrointestinal tract as a whole. Patients in this group noted an improvement in digestion and bowel movements. Conclusion The study showed that the quality of life of patients with gastric cancer largely depends on their nutritional deficiency, and nutritional therapy at the stages of surgical treatment, in turn, can significantly improve its results, including in the aspect of their perception by patients. Using the general EORTC QLQ-C30 questionnaire is one of the available methods for assessing the quality of life in patients with gastric cancer.


2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Hugo Teixeira Farinha ◽  
Fabian Grass ◽  
Amaniel Kefleyesus ◽  
Chahin Achtari ◽  
Benoit Romain ◽  
...  

Background. Peritoneal cancer treatment aims to prolong survival, but preserving Quality of Life (QoL) under treatment is also a priority. Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) is a novel minimally invasive repeatable treatment modality. The aim of the present study was to assess QoL in our cohort of PIPAC patients. Methods. Analysis of all consecutive patients included from the start of PIPAC program (January 2015). QoL (0–100: optimal) and symptoms (no symptom: 0–100) were measured prospectively before and after every PIPAC procedure using EORTC QLQ-C30. Results. Forty-two patients (M : F = 8 : 34, median age 66 (59–73) years) had 91 PIPAC procedures in total (1 : 4x, 17 : 3x, 12 : 2x, and 12 : 1x). Before first PIPAC, baseline QoL was measured as median of 66±2.64. Prominent complaints were fatigue (32±4.3) and digestive symptoms as diarrhea (17±3.75), constipation (17±4.13), and nausea (7±2.54). Overall Quality of Life was 64±3.75 after PIPAC#1 (p=0.57), 61±4.76 after PIPAC#2 (p=0.89), and 70±6.67 after PIPAC#3 (p=0.58). Fatigue symptom score was 44±4.86 after PIPAC#1 and 47±6.69 and 34±7.85 after second and third applications, respectively (p=0.40). Diarrhea (p=0.31), constipation (p=0.76), and nausea (p=0.66) did not change significantly under PIPAC treatment. Conclusion. PIPAC treatment of peritoneal carcinomatosis had no negative impact on patients’ overall QoL and its components or on main symptoms. This study was registered online on Research Registry (UIN: 1608).


2015 ◽  
Vol 174 (4) ◽  
pp. 50-52
Author(s):  
T. B. Duboshina ◽  
M. P. Askerov ◽  
O. A. Zhmyleva

The authors analyzed quality of life before and after thyroid surgery in 350 patients. The article suggested the ways of improving of surgical treatment by developing some technical details. Indications to operation and choice of the operation volume were specified by morphological diagnostics refinement.


2019 ◽  
pp. 244-251
Author(s):  
A. S. Yunusov ◽  
T. I. Garashchenko ◽  
P. I. Belavina ◽  
A. G. Ryazanskaya ◽  
E. V. Molodtsova ◽  
...  

Rationale. Currently, the literature describes about 374 cases of Marshall syndrome. According to some authors, the prevalence of Marshall syndrome is 2.3 per 10,000 children, in general, the epidemiology of PFAPA syndrome in the pediatric population is unknown.Purpose. The aim of our study is to justify surgical treatment in children with Marshall syndrome. Objectives. The objectives of this study are to give a comparative assessment of the effectiveness of tonsillectomy and adenotonzyllectomy for this syndrome and to evaluate the quality of life indicators before and after surgical treatment.Materials and methods. The study included 26 patients with Marshall syndrome, of which 18 patients underwent adenotonzyllectomy and 8 patients underwent bilateral tonsillectomy. A clinical case of a typical manifestation of Marshall syndrome is also described, and follow-up results of the effectiveness of surgical treatment for Marshall syndrome are presented. In the course of the work, an adapted questionnaire was developed to assess the quality of life of parents of children with Marshall syndrome.Results. The result of our work is the fact that in relation to the relief of PFAPA-syndrome, children of preschool and primary school age have more effective adenotonsillectomy (88.2%), while tonsillectomy was effective only in 55.6% of patients.Conclusion. A multidisciplinary approach is required to address the diagnosis and treatment of Marshall syndrome.


2021 ◽  
Vol Volume 14 ◽  
pp. 1215-1230
Author(s):  
Henrik Bjarke Vaegter ◽  
Lars Oxlund Christoffersen ◽  
Thomas Peter Enggaard ◽  
Dorte Elise Møller Holdggard ◽  
Tram Nguyen Lefevre ◽  
...  

2015 ◽  
Vol 6 (3) ◽  
pp. 48-51 ◽  
Author(s):  
Nikolay Yurevich Kokhanenko ◽  
Konstantin Vadimovich Pavelets ◽  
Yuri Vasilevich Radionov ◽  
Yurii Nikolaevich Shiryajev ◽  
Natalya Yurevna Borisova

The authors performed a comparative analysis of the Quality of life (QOL) in 97 patients after pancreatoduodenectomy, 55 of whom underwent pylorus-preserving surgery (PPDE), and 42 underwent classic Whipple procedure (GPDE). QOL was evaluated using questionnaire EORTC-QLQ-C30, version 3.0, and both analyzed groups were divided into 3 subgroups according to the time period after the surgery (less than 6 mo, 6-12 mo, and more than 12 mo). All the patients were operated on for pancreatic or periampullary cancer. During the first period after surgery (less than 6 mo), the integral QOL index is lower than in patients who were examined after the first 6 mo. After PPDE, parameters of physical, role, emotional, cognitive, and social functioning were higher than after GPDE; however, these differences were not statistically significant (p > 0,05). Indicators of QOL have changed with time, but intergroup (PPDE vs GPDE) differences were not statistically significant in every analyzed time period after surgery. Financial constrains were registered in patients of both groups and at different times after surgical treatment.


Sign in / Sign up

Export Citation Format

Share Document