First-passage times with PFr densities

1985 ◽  
Vol 22 (1) ◽  
pp. 185-196 ◽  
Author(s):  
David Assaf ◽  
Moshe Shared ◽  
J. George shanthikumar

It is shown that if a finite-state continuous-time Markov process can be uniformized such that the embedded Markov chain has a TPr (totally positive of order r) transition matrix, then the first-passage time from state 0 to any other state has a PFr (Polya frequency of order r) density. As a consequence, results of Keilson (1971), Esary, Marshall and Proschan (1973), Ghosh and Ebrahimi (1982) and Derman, Ross and Schechner (1983) are strengthened. It is also shown that some cumulative damage shock models, with an underlying compound Poisson process and ‘damages' which are not necessarily non-negative, are associated with wear processes having PFr first-passage times to any threshold. First-passage times with completely monotone densities are also discussed.

1985 ◽  
Vol 22 (01) ◽  
pp. 185-196
Author(s):  
David Assaf ◽  
Moshe Shared ◽  
J. George shanthikumar

It is shown that if a finite-state continuous-time Markov process can be uniformized such that the embedded Markov chain has a TPr (totally positive of order r) transition matrix, then the first-passage time from state 0 to any other state has a PF r (Polya frequency of order r) density. As a consequence, results of Keilson (1971), Esary, Marshall and Proschan (1973), Ghosh and Ebrahimi (1982) and Derman, Ross and Schechner (1983) are strengthened. It is also shown that some cumulative damage shock models, with an underlying compound Poisson process and ‘damages' which are not necessarily non-negative, are associated with wear processes having PF r first-passage times to any threshold. First-passage times with completely monotone densities are also discussed.


1989 ◽  
Vol 3 (1) ◽  
pp. 77-88 ◽  
Author(s):  
Joseph Abate ◽  
Ward Whitt

The distribution of upward first passage times in skip-free Markov chains can be expressed solely in terms of the eigenvalues in the spectral representation, without performing a separate calculation to determine the eigenvectors. We provide insight into this result and skip-free Markov chains more generally by showing that part of the spectral theory developed for birth-and-death processes extends to skip-free chains. We show that the eigenvalues and eigenvectors of skip-free chains can be characterized in terms of recursively defined polynomials. Moreover, the Laplace transform of the upward first passage time from 0 to n is the reciprocal of the nth polynomial. This simple relationship holds because the Laplace transforms of the first passage times satisfy the same recursion as the polynomials except for a normalization.


Mathematics ◽  
2020 ◽  
Vol 8 (11) ◽  
pp. 1988
Author(s):  
Zbigniew Palmowski

In this paper, I analyze the distributional properties of the busy period in an on-off fluid queue and the first passage time in a fluid queue driven by a finite state Markov process. In particular, I show that the first passage time has a IFR distribution and the busy period in the Anick-Mitra-Sondhi model has a DFR distribution.


2020 ◽  
Author(s):  
Krishna Rijal ◽  
Ashok Prasad ◽  
Dibyendu Das

Protein thresholds have been shown to act as an ancient timekeeping device, such as in the time to lysis of E. coli infected with bacteriophage lambda. The time taken for protein levels to reach a particular threshold for the first time is defined as the first passage time of the protein synthesis system, which is a stochastic quantity. The first few moments of the distribution of first passage times were known earlier, but an analytical expression for the full distribution was not available. In this work, we derive an analytical expression for the first passage times for a long-lived protein. This expression allows us to calculate the full distribution not only for cases of no self-regulation, but also for both positive and negative self-regulation of the threshold protein. We show that the shape of the distribution matches previous experimental data on lambda-phage lysis time distributions. We also provide analytical expressions for the FPT distribution with non-zero degradation in Laplace space. Furthermore, we study the noise in the precision of the first passage times described by coefficient of variation (CV) of the distribution as a function of the protein threshold value. We show that under conditions of positive self-regulation, the CV declines monotonically with increasing protein threshold, while under conditions of linear negative self-regulation, there is an optimal protein threshold that minimizes the noise in the first passage times.


1997 ◽  
Vol 34 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Haijun Li ◽  
Moshe Shaked

Using a matrix approach we discuss the first-passage time of a Markov process to exceed a given threshold or for the maximal increment of this process to pass a certain critical value. Conditions under which this first-passage time possesses various ageing properties are studied. Some results previously obtained by Li and Shaked (1995) are extended.


The theory of first-passage times of Brownian motion is developed in general, and it is shown that for certain special boundaries—the only ones of any importance—mean first-passage times can be derived very simply, avoiding the usual method involving series. Moreover, these formulae have a close analytical relationship to the better-known type of formulae for average 'displacements’ in given intervals; there exist certain pairs of reciprocal relations. Some new formulae, of mathematical interest, for translational Brownian motion are given. The main application of the general theory, however, lies in the derivation of experimentally particularly useful formulae for rotational Brownian motion. Special cases when external forces are present, and mean reciprocal first-passage times are discussed briefly, and finally it is shown how finite times of observation modify the mean first-passage time formulae of free Brownian motion.


1987 ◽  
Vol 24 (1) ◽  
pp. 235-240 ◽  
Author(s):  
U. Sumita

Let N(t) be a birth-death process on 𝒩= {0, 1, 2, ·· ·} governed by the transition rates λn > 0 (n ≧ 0) and μn > 0 (n ≧ 1) where λn → λ > 0 and μn → μ > 0 as n → ∞ and ρ = λ/μ. Let Tmn be the first-passage time of N(t) from m to n and define It is shown that, when converges in distribution to TBP(μ,λ) as n → ∞ where TΒΡ (μ,λ) is the server busy period of an M/M/1 queueing system with arrival rate μ and service rate λ. Correspondingly T0n/E[T0n] converges to 1 with probability 1 as n →∞. Of related interest is the conditional first-passage time mTrn of N(t) from r to n given no visit to m where m < r < n. As we shall see, the conditional first-passage time of N(t) can be viewed as an ordinary first-passage time of a modified birth-death process M(t) governed by where are generated from λn and μn. Furthermore it is shown that for and while for and This enables one to establish the relation between the limiting behavior of the ordinary first-passage times and that of the conditional first-passage times.


1997 ◽  
Vol 34 (01) ◽  
pp. 1-13 ◽  
Author(s):  
Haijun Li ◽  
Moshe Shaked

Using a matrix approach we discuss the first-passage time of a Markov process to exceed a given threshold or for the maximal increment of this process to pass a certain critical value. Conditions under which this first-passage time possesses various ageing properties are studied. Some results previously obtained by Li and Shaked (1995) are extended.


1987 ◽  
Vol 24 (01) ◽  
pp. 235-240 ◽  
Author(s):  
U. Sumita

LetN(t) be a birth-death process on 𝒩= {0, 1, 2, ·· ·} governed by the transition ratesλn&gt; 0 (n≧ 0) andμn&gt; 0 (n≧ 1) whereλn→λ&gt; 0 andμn→μ&gt; 0 asn→ ∞ andρ=λ/μ. LetTmnbe the first-passage time ofN(t) frommtonand defineIt is shown that, whenconverges in distribution toTBP(μ,λ)asn → ∞whereTΒΡ (μ,λ)is the server busy period of anM/M/1 queueing system with arrival rateμand service rateλ. CorrespondinglyT0n/E[T0n] converges to 1 with probability 1 asn→∞. Of related interest is the conditional first-passage timemTrnofN(t) from r tongiven no visit tomwherem &lt; r &lt; n.As we shall see, the conditional first-passage time ofN(t) can be viewed as an ordinary first-passage time of a modified birth-death processM(t) governed bywhereare generated fromλnandμn. Furthermore it is shown that forandwhile forandThis enables one to establish the relation between the limiting behavior of the ordinary first-passage times and that of the conditional first-passage times.


2020 ◽  
Vol 52 (2) ◽  
pp. 681-704
Author(s):  
Angelos Dassios ◽  
Luting Li

AbstractWe introduce a unified framework for solving first passage times of time-homogeneous diffusion processes. Using potential theory and perturbation theory, we are able to deduce closed-form truncated probability densities, as asymptotics or approximations to the original first passage time densities, for single-side level crossing problems. The framework is applicable to diffusion processes with continuous drift functions; in particular, for bounded drift functions, we show that the perturbation series converges. In the present paper, we demonstrate examples of applying our framework to the Ornstein–Uhlenbeck, Bessel, exponential-Shiryaev, and hypergeometric diffusion processes (the latter two being previously studied by Dassios and Li (2018) and Borodin (2009), respectively). The purpose of this paper is to provide a fast and accurate approach to estimating first passage time densities of various diffusion processes.


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