AbstractThe aim of this paper is to offer an insight into innovation management in the knowledge-based society. It sets off by explaining the concept of knowledge-based society and why it bears relevance for the modern world. Next, innovation and related concepts are introduced. Furthermore, a presentation of National Innovation Systems (NIS) is made, their history and role in the understanding of a systemic approach to research, development and innovation at both national and global level. Next, the OECD main guidelines for the elaboration of national innovation policies are presented. Last but not least, an analysis of the current situation of research and innovation in Romania is also included.