Differences in Body Composition Convey a Similar Risk of Type 2 Diabetes Among Different Ethnic Groups With Disparate Cardiometabolic Risk—The HELIUS Study

Diabetes Care ◽  
2021 ◽  
pp. dc210230
Author(s):  
Marleen Zethof ◽  
Charlotte M. Mosterd ◽  
Didier Collard ◽  
Henrike Galenkamp ◽  
Charles Agyemang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Composition ◽  
Ethnic Groups ◽  
Cardiometabolic Risk ◽  
Helius Study ◽  
Similar Risk

scholarly journals Differences in Body Composition Convey a Similar Risk of Type 2 Diabetes Among Different Ethnic Groups With Disparate Cardiometabolic Risk—The HELIUS Study

2021 ◽  
Author(s):  
Marleen Zethof ◽  
Charlotte M. Mosterd ◽  
Didier Collard ◽  
Henrike Galenkamp ◽  
Charles Agyemang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Composition ◽  
Ethnic Groups ◽  
South Asian ◽  
Cardiometabolic Risk ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
C Statistic ◽  
Helius Study

<b>Objective</b>: Studies have shown a disparate association between body composition and the risk of type 2 diabetes. We assessed whether associations between differences in body composition and type 2 diabetes vary among ethnic groups with disparate cardiometabolic risk. <p><b>Research Design and Methods: </b>We used data from the HELIUS study, including individuals aged 18-70 of<b> </b>African Surinamese (n=3997), South-Asian Surinamese (n=2956), Turkish (n=3546), Moroccan (n=3850), Ghanaian (n=2271) and Dutch (n=4452) origin living in Amsterdam. Type 2 diabetes was defined using the World Health Organization criteria. Logistic regression was used to assess the relation between body composition and type 2 diabetes. Waist-hip ratio, waist circumference, BMI and body fat percentage by bio-electrical impedance were used to estimate body composition.</p> <p><b>Results: </b>Per unit change in BMI only Ghanaian [OR 0.94 (95% CI 0.89-0.99)] and Moroccan [0.94 (0.89-0.99)] women had a smaller increase in type 2 diabetes per unit change in BMI compared to the Dutch population, while OR for body fat percentage were 0.94 (0.89-1.00) for Ghanaian, 0.93 (0.88-0.99) for Moroccan and 0.95 (0.90-1.00) for South-Asian Surinamese women. There was no interaction between WHR and ethnicity on the risk of type 2 diabetes, and there were no differences in men. WHR had the highest precision in predicting type 2 diabetes in both men (c-statistic=0.78) and women (c-statistic=0.81). </p> <b>Conclusions: </b>The<b> </b>association between differences in body composition and type 2 diabetes is roughly the same in all ethnic groups. WHR seems the most reliable and consistent predictor of type 2 diabetes regardless of ethnic background.<b> </b>

scholarly journals Differences in Body Composition Convey a Similar Risk of Type 2 Diabetes Among Different Ethnic Groups With Disparate Cardiometabolic Risk—The HELIUS Study

2021 ◽  
Author(s):  
Marleen Zethof ◽  
Charlotte M. Mosterd ◽  
Didier Collard ◽  
Henrike Galenkamp ◽  
Charles Agyemang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Composition ◽  
Ethnic Groups ◽  
South Asian ◽  
Cardiometabolic Risk ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
C Statistic ◽  
Helius Study

<b>Objective</b>: Studies have shown a disparate association between body composition and the risk of type 2 diabetes. We assessed whether associations between differences in body composition and type 2 diabetes vary among ethnic groups with disparate cardiometabolic risk. <p><b>Research Design and Methods: </b>We used data from the HELIUS study, including individuals aged 18-70 of<b> </b>African Surinamese (n=3997), South-Asian Surinamese (n=2956), Turkish (n=3546), Moroccan (n=3850), Ghanaian (n=2271) and Dutch (n=4452) origin living in Amsterdam. Type 2 diabetes was defined using the World Health Organization criteria. Logistic regression was used to assess the relation between body composition and type 2 diabetes. Waist-hip ratio, waist circumference, BMI and body fat percentage by bio-electrical impedance were used to estimate body composition.</p> <p><b>Results: </b>Per unit change in BMI only Ghanaian [OR 0.94 (95% CI 0.89-0.99)] and Moroccan [0.94 (0.89-0.99)] women had a smaller increase in type 2 diabetes per unit change in BMI compared to the Dutch population, while OR for body fat percentage were 0.94 (0.89-1.00) for Ghanaian, 0.93 (0.88-0.99) for Moroccan and 0.95 (0.90-1.00) for South-Asian Surinamese women. There was no interaction between WHR and ethnicity on the risk of type 2 diabetes, and there were no differences in men. WHR had the highest precision in predicting type 2 diabetes in both men (c-statistic=0.78) and women (c-statistic=0.81). </p> <b>Conclusions: </b>The<b> </b>association between differences in body composition and type 2 diabetes is roughly the same in all ethnic groups. WHR seems the most reliable and consistent predictor of type 2 diabetes regardless of ethnic background.<b> </b>

Serum carotenoid concentrations and their association with ethnic differences in type 2 diabetes within the Healthy Life in an Urban Setting (HELIUS) study

2020 ◽  
pp. 1-10
Author(s):  
P Flores Sanchez ◽  
M Muilwijk ◽  
M Nicolaou ◽  
MB Snijder ◽  
RJG Peters ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Ethnic Groups ◽  
Ethnic Differences ◽  
Vegetable Intake ◽  
Fruit And Vegetable Intake ◽  
Urban Setting ◽  
Healthy Life ◽  
Helius Study ◽  
Serum Carotenoids

Abstract Objective: Studies have reported an inverse association between a diet rich in fruits and vegetables and type 2 diabetes (T2D), but data on high-risk ethnic minority groups is limited. We investigated whether serum carotenoids, as biomarkers for fruit and vegetable intake, mediate ethnic differences in the prevalence of T2D. Design: Age-adjusted serum carotenoid concentrations were compared using ANCOVA. A cross-sectional analysis was performed using Cox regression to estimate prevalence ratios (PR) and their 95 % CI of the association between serum carotenoid concentrations and T2D. To study whether serum carotenoids potentially mediate the differences in the prevalence of T2D across ethnic groups, we compared PR of the model including known risk factors and the model additionally adjusted for serum carotenoid concentrations using the Dutch group as reference. Setting: A study among six ethnic groups living in Amsterdam, the Netherlands. Participants: Data on 204 Dutch, 203 South Asian Surinamese, 204 African Surinamese, 203 Turkish and 200 Moroccan-origin participants from the Healthy Life in an Urban Setting (HELIUS) study were used. Results: Serum carotenoid concentrations differed across ethnic groups. After adjusting for confounders, the serum concentrations of total carotenoids (PR 0·67, 95 % CI 0·54, 0·84), α-carotene (PR 0·57, 95 % CI 0·42, 0·77), β-carotene (PR 0·45, 95 % CI 0·32, 0·63) and β-cryptoxanthin (PR 0·73, 95 % CI 0·58, 0·92) were inversely associated with T2D. Despite the associations, serum carotenoids did not mediate the ethnic differences in the prevalence of T2D. Conclusions: The limited contribution of serum carotenoids to ethnic differences in T2D suggests that a focus on increasing fruit and vegetable intake alone will not likely eliminate ethnic differences in T2D prevalence.

scholarly journals The Association of Handgrip Strength and Type 2 Diabetes Mellitus in Six Ethnic Groups: An Analysis of the HELIUS Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0137739 ◽  
Author(s):  
Anne-Lotte L. F. van der Kooi ◽  
Marieke B. Snijder ◽  
Ron J. G. Peters ◽  
Irene G. M. van Valkengoed
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Ethnic Groups ◽  
Handgrip Strength ◽  
Helius Study

scholarly journals Dairy Consumption and Cardiometabolic Risk Factors in Patients with Type 2 Diabetes and Obesity During Intensive Lifestyle Intervention: A 6-Month Prospective Cohort Study

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 668-668
Author(s):  
Shaheen Tomah ◽  
Veronica Salsberg ◽  
Ahmed H Eldib ◽  
Mhd Wael Tasabehji ◽  
Osama Hamdy
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Body Composition ◽  
Body Weight ◽  
Cardiometabolic Risk ◽  
Caloric Intake ◽  
The Other ◽  
Intensive Lifestyle Intervention ◽  
Dairy Consumption

Abstract Objectives To evaluate the association between dairy consumption and A1C, body weight, and cardiometabolic risk factors in patients with type 2 diabetes (T2D) and obesity enrolled in a 12-week intensive lifestyle intervention (ILI) program in real-world clinical practice. Methods We evaluated 45 subjects with T2D and obesity enrolled in a 12-week ILI program (mean age 56 ± 9 yrs, 40% female, diabetes duration 10.9 ± 7 yrs, A1C 7.9 ± 1.3%, body weight 106 ± 19 kg, BMI 36 ± 5 kg/m2, and caloric intake 1880 ± 544 kcal/d). We divided the cohort based on weekly average dairy consumption during the 12-week ILI program equally into frequent, less-frequent, and infrequent dairy consumers (1.5 ± 0.6 servings/d, 0.6 ± 0.2 servings/d, and 0.2 ± 0.1 servings/d respectively). High- and low-fat dairy consumption was balanced within the 3 groups. We continued to follow them for additional 12 weeks after the end of the ILI program. Clinical, dietary, and body composition measurements were done at baseline, 12 weeks, and 24 weeks. Results At baseline, there was no significant difference between the 3 groups except for higher caloric intake among frequent compared with infrequent dairy consumers (2106 ± 498 kcal vs 1496 ± 540 kcal, P &lt; 0.01). Frequent dairy consumers increased their %energy from protein from baseline by 5.8 ± 2.3% at 12 weeks and 3.6 ± 2% at 24 weeks (P &lt; 0.05 for both), while the other 2 groups had no changes. There were no significant changes in % energy from fat, saturated fat, carbohydrates, fibers or alcohol consumption between the 3 groups. After the ILI program, the less-frequent group increased their average dairy consumption by 33% to 0.8 ± 0.3 servings/d at 6 months (P &lt; 0.05), while the other 2 groups had no changes. There was a trend towards lower serum HDL-C and higher VLDL-C and insulin with frequent dairy consumption at 12 weeks and 6 months (P trend &lt; 0.05). Changes in A1C, body weight, HOMA-IR, total cholesterol, LDL-C, BP, or body composition parameters showed no association with the frequency of dairy consumption at 12 weeks or 6 months. Conclusions Frequency of dairy consumption during ILI program is not associated with changes in A1C or body weight but with unfavorable trends in serum HDL-C, VLDL-C and Insulin in patients with T2D and obesity. Funding Sources This investigator-initiated study was funded by the National Dairy Council.

Prevalence of type 2 diabetes and its association with measures of body composition among African residents in the Netherlands – The HELIUS study

2015 ◽  
Vol 110 (2) ◽  
pp. 137-146 ◽  
Author(s):  
Karlijn A.C. Meeks ◽  
Karien Stronks ◽  
Erik J.A.J. Beune ◽  
Adebowale Adeyemo ◽  
Peter Henneman ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Composition ◽  
The Netherlands ◽  
Helius Study

Adapted recreational football small-sided games improve cardiac capacity, body composition and muscular fitness in patients with type 2 diabetes

2020 ◽  
Vol 60 (9) ◽  
Author(s):  
Annamaria Mancini ◽  
Anna A. Turco ◽  
Carlo G. Tocchetti ◽  
Georgios Ermidis ◽  
Francesca Cozzolino ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Composition ◽  
Muscular Fitness
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