PROVISION OF VITAMIN D FOR CHILDREN AND ADOLESCENTS IN THE CITY OF ULAN-UDE

2021 ◽  
Vol 100 (3) ◽  
pp. 295-300
Author(s):  
N.B. Gomboeva ◽  
◽  
E.I. Grigoryeva ◽  
Keyword(s):  
Vitamin D ◽  
Children And Adolescents ◽  
Vitamin D Deficiency ◽  
Respiratory Infections ◽  
Sharp Decrease ◽  
The Body ◽  
Severe Deficiency ◽  
Significant Difference ◽  
25 Oh Vitamin D ◽  
The City

The proven relationship between the frequency of influenza and acute respiratory infections in children with vitamin D deficiency and the data on the relationship between a high mortality rate from SARS-CoV-2 in patients with low levels of vitamin D in the body under conditions of a forced sharp decrease in the level of insolation in the period from March 11, 2020 dictated the relevance assessing the vitamin D supply of children and adolescents in educational organizations of the city of Ulan-Ude. Purpose of the study: to assess the vitamin D supply of children and adolescents living in the city of Ulan-Ude. Methods: in a non-randomized, single-center, transverse (one-stage) uncontrolled comparative study, the concentration of 25(OH) vitamin D – 25(OH)D – in the blood serum of children and adolescents in Ulan-Ude was studied from May 22 to May 24, 2020. Moderate vitamin D deficiency (deficiency) was determined when the content of 25(OH)D was in the range of 20–30 ng/ml, the deficiency was within the limits, and the severe deficiency was <10 ng/ml. Results: assessment of vitamin D provision was carried out in 60 children aged 10 to 17 years (15 [11; 16] years), of which 19 boys, 41 girls. Children were divided into 2 groups depending on age: 10–11 years old (grade 5) (n=27) and 15–17 years old (grades 9–11) (n=33). Deficiency of vitamin D was found in 4 (15%), 11 (33%); deficit – in 19 (70%), 18 (55%); severe deficiency – in 2 (7%), 4 (12%), respectively. Along with low indicators of the provision of children and adolescents in the city of Ulan-Ude, an even lower provision of children and adolescents of Buryats was noted. The concentration of vitamin D in Buryat children and adolescents below normal (less than 30 ng/ml) was found in 35 (100%) children and adolescents, deficiency – in 8 (23%) children, vitamin D deficiency – in 21 (60%) children and severe deficiency – in 6 (17%). A statistically significant difference in the content of 25(OH)D between children and adolescents of Russian nationality and Buryats was revealed (p=0,0056). Evaluation of the diet showed that the frequency of consumption of fish as a source of vitamin D by children and adolescents is low. Conclusion: there is a high incidence of vitamin D deficiency and deficiency, which amounted to 97% in the examined children and adolescents living in the city of Ulan-Ude, more pronounced in Buryat children and adolescents, which requires organizational measures to replenish the vitamin D deficiency.

Evaluation of Vitamin D Deficiency and Its Relationship with Body Mass Index in Children 1 To 16 Years

2021 ◽  
Author(s):  
Elham Nozari Mirarkolaei ◽  
Mahdi Gholami ◽  
Elham Rostami ◽  
Azita Aliakbarniya ◽  
Massoumeh Hotelchi ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Vitamin D ◽  
Children And Adolescents ◽  
Vitamin D Deficiency ◽  
Body Mass ◽  
Body Weight Gain ◽  
Thyroid Stimulating Hormone ◽  
Overweight And Obesity ◽  
Mazandaran Province ◽  
Significant Difference

Introduction: Body weight gain in children and teenagers is one of the major challenges that cause undesirable health outcomes. Simultaneously with the prevalence of overweight and obesity, children and adolescents are diagnosed with 25-hydroxyvitamin D (25(OH)D) deficiency in different sides of the world. The present study aimed to assess 25(OH)D status among Iranian volunteers aged 1-16 years and find the correlation between 25(OH)D status and body mass index (BMI) subjects.    Material and Methods: The total volunteers included 807 Iranian children aged 1 to 16 referred to the general and endocrinology clinics in Babol city, Mazandaran Province. A trained physician determined anthropometric characteristics. Serum levels of calcium (Ca), phosphate (P), creatinine (Cr), urea, thyroxine (T4), thyroid-stimulating hormone (TSH), and 25(OH)D were assessed in all children.      Results: 25.27% of the children were 25(OH)D deficient, and 59.1% were insufficient. There was no significant difference in serum 25(OH)D level between girls and boys (P=0.13). A significant negative correlation was found in serum 25(OH)D level with weight (P=0.000, r=-0.12), BMI (P=0.000, r=-0.13), and age (P=0.000, r=-0.13). Conclusion: These data displayed that 25(OH)D insufficiency is highly prevalent among children in the north of Iran. Serum 25(OH)D levels are affected by age and BMI value. Improving vitamin D deficiency helps to maintain the health of children and adolescents during this critical period.

scholarly journals Vitamin D deficiency in critically ill patients with traumatic injuries

2016 ◽  
Vol 4 ◽  
pp. 1-9 ◽  
Author(s):  
Roland N. Dickerson ◽  
Jonathan R. Van Cleve ◽  
Joseph M. Swanson ◽  
George O. Maish ◽  
Gayle Minard ◽  
...  
Keyword(s):  
Vitamin D ◽  
African American ◽  
Vitamin D Deficiency ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Traumatic Injuries ◽  
Severe Deficiency ◽  
Severity Of Injury ◽  
25 Oh Vitamin D ◽  
African American Race

Abstract Background Vitamin D depletion has been associated with increased rate of infections, lengthened hospital stay, and worsened mortality for critically ill patients. The purpose of this study was to evaluate the prevalence and variables associated with vitamin D deficiency in critically ill patients with severe traumatic injuries. Methods Critically ill adult patients admitted to the trauma intensive care unit (ICU) between June 2013 and June 2014, referred to the nutrition support service for enteral or parenteral nutrition, and had a serum 25-hydroxyvitamin D (25-OH vitamin D) concentration determination were retrospectively evaluated. Patients were stratified as vitamin D sufficient, insufficient, deficient, or severely deficient based on a 25-OH vitamin D concentration of 30–80, 20–29.9, 13.1–19.9, and ≤13 ng/mL, respectively. Results One hundred and twenty-one patients out of 158 (76 %) patients were vitamin D deficient or severely deficient. Thirty-one patients (20 %) were insufficient and 6 (4 %) had a normal 25-OH vitamin D concentration. 25-OH vitamin D was determined 7.5 ± 5.1 days after ICU admission. African-Americans had a greater proportion of patients with deficiency or severe deficiency compared to other races (91 versus 64 %, P = 0.02). Penetrating gunshot or knife stab injury, African-American race, and obesity (elevated body mass index) were significantly associated with vitamin D deficiency or severe deficiency: OR 9.23 (1.13, 75.40), 4.0 (1.4, 11.58), and 1.12 (1.03, 1.23), P &lt; 0.05, respectively. Conclusions The majority of critically ill patients with traumatic injuries exhibit vitamin D deficiency or severe deficiency. Penetrating injuries, African-American race, and obesity are significant risk factors for deficiency. Severity of injury, extent of inflammation (elevated C-reactive protein concentration), or hospital admission during the winter season did not significantly influence the prevalence of vitamin D deficiency.

scholarly journals Factors affecting vitamin D status in Moscow adolescents

2019 ◽  
pp. 50-57
Author(s):  
I. N. Zakharova ◽  
E. A. Solov’yeva ◽  
T. M. Tvorogova ◽  
S. I. Lazareva ◽  
T. Yu. Vil’ken ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Respiratory Infections ◽  
Endocrine System ◽  
Risk Groups ◽  
The Body ◽  
Gastrointestinal Pathology ◽  
Vitamin D Levels ◽  
The Impact

Justification of the study. The normalization of vitamin D levels in both children and adults is the goal of numerous studies around the world, and the setting of a number of objectives related to this vector of preventive medicine, dictates the need for a more detailed study of regional features of the status of calcidiol and the identification of both risk factors and risk groups. Aim of the study: to analyze the impact of risk factors on the provision of vitamin D to adolescents in the Moscow region. Methods: 360 children over 11 years of age (average age was 14.74 ± 1.92 years) who attended a children’s polyclinic for preventive check-ups or are under observation in a day-care centre. After the examination, all schoolchildren were determined to have serum content of calcidiol – active metabolite of vitamin D. Results: the analysis revealed low vitamin D levels in children, with a median of 16.1 ng/ml. Normal vitamin D levels were found in only 6.7% of cases. The following risk factors for vitamin D deficiency were identified in Moscow schoolchildren: time of year (p < 0.001), inclusion of such foods as fish (p = 0.021) and liver (p = 0.036), gastrointestinal pathology (p < 0.001), endocrine system pathology (p < 0.001), musculoskeletal system pathology (p = 0.045): course of chronic inflammatory process (p = 0.01) in the body. The correlation between acute respiratory diseases and calcidiol supply was analyzed: at low frequency of acute respiratory infections during the year, the median level of vitamin D was 17.1 ng/ml (Q1-Q3: 12.6-22.1 ng/ml), at an average frequency – 11.4 ng/ml (Q1-Q3: 8.45-16.05 ng/ml), at high frequency – decreased to 7.94 ng/ml (Q1-Q3: 5.89-9.06 ng/ml). Conclusion: Vitamin D deficiency prophylaxis should be provided to children all year round, without a break for the summer months. If a child has a risk factor for vitamin D deficiency, the metabolite correction should be controlled by the calcidiol serum content.

scholarly journals Vitamin D deficiency in children

2014 ◽  
Vol 6 (1) ◽  
pp. 1-7
Author(s):  
Mohd Ashraf ◽  
Mohammad Ishaq ◽  
Nazir Ahmed Parrey ◽  
Kaisar Ahmed
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
English Language ◽  
Respiratory Infections ◽  
Pediatric Population ◽  
Failure To Thrive ◽  
Diabetes Mellitus Type 1 ◽  
Health Related ◽  
Medical Entity ◽  
25 Oh Vitamin D

Background: Vitamin D deficiency in children is an important medical entity commonly diagnosed during early childhood. Prevalence and incidence of vitamin D deficiency in children is underestimated and can have far reaching consequences as per the latest evidence. Children at high risk should be identified and treated accordingly to avoid the treatable misadventures of future life. Aim: The purpose of this review is to provide summary of the latest research in particular to the practical aspects of vitamin D deficiency in children. Methods: A literature search in PubMed, Medline, Embase, Scopus, Google Scholar, and DOAJ was conducted, regarding pediatric vitamin D deficiency related research and review articles in English language, using keywords or phrases such as bones; childhood allergy; calcium; children; diabetes mellitus type 1; respiratory infections; rickets; failure to thrive, 25-OH vitamin D. Conclusion: Despite major advances in unfolding the classical and non-classical role of vitamin D in various health related events in children, yet most of the pediatric population is vitamin D deficient even in countries like India with ample sunlight.DOI: http://dx.doi.org/10.3126/ajms.v6i1.10199 Asian Journal of Medical Sciences Vol.6(1) 2015 1-7

scholarly journals Vitamin D status in 3-6-year-old children of Mananthavady ICDS block in Wayanad, Kerala, India

2018 ◽  
Vol 5 (4) ◽  
pp. 1226
Author(s):  
Arif Mohamed Khan ◽  
T. G. Sindhu ◽  
M. Vijayakumar
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Cross Sectional Study ◽  
Tribal Community ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
High Prevalence ◽  
25 Oh Vitamin D ◽  
Kerala State

Background: Despite plenty of sunlight, vitamin D deficiency has been reported in both urban and rural population in India. This study was conducted to estimate the prevalence of Vitamin D deficiency in children between 3-6 years of age group belonging to Mananthavady ICDS block of Wayanad and to identify the sociodemographic variables affecting its level.Methods: This descriptive cross-sectional study was conducted from December 2014 to June 2015. 140 children were selected from 20 Anganawadis in Mananthavady ICDS block in Wayanad district of Kerala state by random methods. After taking relevant history and conducting detailed clinical examinations, blood samples were taken to assess 25(OH) Vitamin D, calcium, phosphorous and alkaline phosphatase levels. Statistical analysis was done using PASW software. Calculations of means were done using descriptive statistics and comparative analysis was done using independent T test.Results: Out of the 140 children 51 belonged to tribal community. The mean 25(OH) Vitamin D level was 22.7ng/ml. 47.1% of the population had deficient, 35% insufficient and 17.9% adequate Vitamin D levels. There was no statistically significant difference in Vitamin D levels between children of tribal and non-tribal community. There was significant increase in Vitamin D levels during summer when compared to that of winter and autumn seasons.Conclusions: There is a high prevalence of vitamin D deficiency among the rural children of 3-6-year age of Mananthavadi ICDS block. The Vitamin D levels were almost equal between the tribal and non-tribal children. Vitamin D levels are significantly higher during summer when compared to other seasons.

scholarly journals PREVALENCE OF VITAMIN D DEFICIENCY IN PEOPLE OVER 50 YEARS OLD RESIDING IN REPUBLIC OF BASHKORTOSTAN IN PERIODS OF LOW INSOLATION

2012 ◽  
Vol 15 (3) ◽  
pp. 7-9 ◽  
Author(s):  
R Z Nurlygayanov ◽  
E R Syrtlanova
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Rural Areas ◽  
Sun Exposure ◽  
Severe Vitamin ◽  
Republic Of Bashkortostan ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
The Republic ◽  
The City

Objectives. To study the vitamin D levels in the period of minimal sun exposure in individuals older than 50 years residing in the Republic of Bashkortostan. Materials and methods. In the period of low insolation (March) in 188 people (68 men and 120 women) aged over 50 years (mean age 66,1 ± 0,75 years) residing in the city (Ufa) and rural areas of the Republic of Bashkortostan we investigated the levels of 25 (OH) D and parathyroid hormone (PTH) by the indirect ELISA. Level of 25 (OH) D 25-50 nmol/l were considered as mild vitamin D deficiency; 12,5-25 nmol/l-as moderate deficiency, and levels below 12.5 nmol/l - as a severe vitamin D deficiency. Results. The average level of 25 (OH) D was 33,55 ± 1,28 nmol/l; in urban area 43,48 ± 1,59 nmol/l; in rural area 21,25 ± 1,06 nmol/l; 36,29±2,43 nmol/l in men; 32,28± 1,47 nmol/l in women. The levels of vitamin D in the urban population were twice as high as in rural areas. A statistically significant difference by gender in terms of the levels of vitamin D was not found. We saw normal levels of vitamin D only in 18 % of subjects (in the city- 30 %, in the rural areas - 2 %), 43 % of people had a mild vitamin D deficiency (in the city - 59 %, in rural areas - 24 %), 33 % - a moderate deficiency of vitamin D (in the city -11 %, in the rural areas - 60 %), and 6 % of the patients had a severe vitamin D deficiency (in the city - 0 %, in rural areas -14 %). Moderate to severe vitamin D deficiency in rural areas was significantly more prevalent (74 %) than in urban (11 %). Gender was not found to be a risk factor for the development of vitamin D deficit in people over 50 years. There was a negative correlation between vitamin D levels and patient age (r=-0,356, p <0,001) and between levels of vitamin D andPTH (r =-0,313, p <0.001).

The relationship between vitamin D deficiency and thoracic aortic dilatation

VASA ◽  
2012 ◽  
Vol 41 (6) ◽  
pp. 419-424 ◽  
Author(s):  
Demir ◽  
Uyan ◽  
Melek
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Control Group ◽  
Aortic Dilatation ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Echocardiographic Parameters ◽  
Basic Characteristics ◽  
Artery Disease ◽  
25 Oh Vitamin D

Background: Vitamin D deficiency can play a role in cardiovascular conditions, such as coronary artery disease, heart failure and hypertension. Vitamin D deficiency can activate the renin-angiotensin-aldosterone system, which in turn affects the cardiovascular system. Thus, a relationship between vitamin D deficiency and thoracic aortic dilatation (TAD) and aneurysm could be postulated. In this study, we compared 25-OH vitamin D levels between TAD and control groups. Patients and methods: This study included 87 patients with TAD who were 40 - 70 years old. The control group consisted of 93 patients who were 40 - 70 years old and did not have TAD. A transthoracic echocardiography was performed on each patient. Along with routine tests, the 25-OH vitamin D and parathormone (PTH) levels were analyzed. Results: No statistically significant difference was found between the two groups regarding their basic characteristics. The average PTH level of the TAD group was higher than that of the control group (94.87 ± 44.96 and 66.39 ± 30.58 pg/ml, respectively; p < 0.001). The average 25-OH vitamin D level of the TAD group was lower than that of the control group (11.89 ± 7.54 and 15.98 ± 4.98 ng/ml, respectively; p = 0.001). The initial conventional echocardiographic parameters of both groups were comparable. Logistic regression analysis revealed that the PTH and 25-OH vitamin D levels were independent predictors of TAD. Conclusions: Vitamin D deficiency was found as an independent factor associated with TAD.

scholarly journals Extra-Skeletal Effects of Vitamin D

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1460 ◽  
Author(s):  
Rose Marino ◽  
Madhusmita Misra
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Immune Modulation ◽  
Mononuclear Cells ◽  
Respiratory Infections ◽  
The Body ◽  
Food Allergies ◽  
Case Control Studies ◽  
Skeletal Effects ◽  
Meta Analyses

The vitamin D receptor is expressed in multiple cells of the body (other than osteoblasts), including beta cells and cells involved in immune modulation (such as mononuclear cells, and activated T and B lymphocytes), and most organs in the body including the brain, heart, skin, gonads, prostate, breast, and gut. Consequently, the extra-skeletal impact of vitamin D deficiency has been an active area of research. While epidemiological and case-control studies have often suggested a link between vitamin D deficiency and conditions such as type 1 and type 2 diabetes, connective tissue disorders, inflammatory bowel disorders, chronic hepatitis, food allergies, asthma and respiratory infections, and cancer, interventional studies for the most part have failed to confirm a causative link. This review examines available evidence to date for the extra-skeletal effects of vitamin D deficiency, with a focus on randomized controlled trials and meta-analyses.

SUBLINGUAL VITAMIN D3 DRUG THERAPY IN VITAMIN D DEFICIENCY PATIENTS AT PRAVARA RURAL HOSPITAL

2019 ◽  
pp. 18-20
Author(s):  
Sanjeeva Kumar Goud T ◽  
Rahul Kunkulol
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vitamin D3 ◽  
Serum Vitamin ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Significant Difference ◽  
Before And After

The present study was aimed to study the effect of Sublingual Vitamin D3 on Serum Vitamin D level in Vitamin D deficiency patients. This was a cross-sectional and interventional study. All the Vitamin D deficiency patients of age 18-60years and either gender, willing to participate in the study were included. Patients who had greater than 20 ng/ml were excluded from the study. The total number of participants in our study was 200, out of these 111 males and 89 females, the mean age in our study was 51.07 ± 7.39Yrs. All volunteers were given sublingual vitamin D3 (60,000IU) in six doses every fifteen days of follow up for 3 months. The subject’s serum 25(OH)D levels were estimated before and after the treatment of sublingual vitamin D3. There was a statistically significant difference in serum vitamin D3 level before 16.61±6.71 ng/ml and after 35.80±7.80 ng/ml after treatment with Sublingual Vitamin D3. Six doses of 60,000IU of Vitamin D3 sublingual route having improved the role of serum 25(OH)D levels in the treatment of Vitamin D3 deficiency patients.Keywords: Vitamin D3; Sublingual route

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