Development and evaluation of a formula to correct blood glucose concentration measurements in hemodiluted and hemoconcentrated feline blood samples tested by use of a veterinary point-of-care glucometer

2019 ◽  
Vol 254 (10) ◽  
pp. 1180-1185 ◽  
Author(s):  
Selena L. Lane ◽  
Amie Koenig
Keyword(s):  
Blood Glucose ◽  
Glucose Concentration ◽  
Blood Glucose Concentration ◽  
Point Of Care ◽  
Blood Samples ◽  
Concentration Measurements

Accuracy and precision assessment of a new blood glucose monitoring system

2016 ◽  
Vol 54 (1) ◽  
Author(s):  
Li-Nong Ji ◽  
Li-Xin Guo ◽  
Li-Bin Liu
Keyword(s):  
Blood Glucose ◽  
Glucose Concentration ◽  
Blood Glucose Concentration ◽  
Venous Blood ◽  
Glucose Monitoring ◽  
Blood Glucose Monitoring ◽  
Blood Samples ◽  
Glucose Testing ◽  
Blood Tests ◽  
Accuracy And Precision

AbstractBlood glucose self-monitoring by individuals with diabetes is essential in controlling blood glucose levels. The International Organization for Standardization (ISO) introduced new standards for blood glucose monitoring systems (BGMS) in 2013 (ISO 15197: 2013). The CONTOUR PLUSThis study evaluated the accuracy and precision of CONTOUR PLUS BGMS in quantitative glucose testing of capillary and venous whole blood samples obtained from 363 patients at three different hospitals.Results of fingertip and venous blood glucose measurements by the CONTOUR PLUS system were compared with laboratory reference values to determine accuracy. Accuracy was 98.1% (96.06%–99.22%) for fingertip blood tests and 98.1% (96.02%–99.21%) for venous blood tests. Precision was evaluated across a wide range of blood glucose values (5.1–17.2 mmol/L), testing three blood samples repeatedly 15 times with the CONTOUR PLUS blood glucose meter using test strips from three lots. All within-lot results met ISO criteria (i.e., SD<0.42 mmol/L for blood glucose concentration <5.55 mmol/L; CV<7.5% for blood glucose concentration ≥5.55 mmol/L). Between-lot variations were 1.5% for low blood glucose concentration, 2.4% for normal and 3.4% for high.Accuracy of both fingertip and venous blood glucose measurements by the CONTOUR PLUS system was >95%, confirming that the system meets ISO 15197: 2013 requirements.

scholarly journals Basal blood glucose concentration in free-living striped mice is influenced by food availability, ambient temperature and social tactic

2015 ◽  
Vol 11 (5) ◽  
pp. 20150208 ◽  
Author(s):  
Carsten Schradin ◽  
Neville Pillay ◽  
Anna Kondratyeva ◽  
Chi-Hang Yuen ◽  
Ivana Schoepf ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Ambient Temperature ◽  
Food Availability ◽  
Glucose Concentration ◽  
Extended Family ◽  
Blood Glucose Concentration ◽  
Energy Regulation ◽  
Free Living ◽  
Blood Samples ◽  
Rhabdomys Pumilio

Vertebrates obtain most of their energy through food, which they store mainly as body fat or glycogen, with glucose being the main energy source circulating in the blood. Basal blood glucose concentration (bBGC) is expected to remain in a narrow homeostatic range. We studied the extent to which bBGC in free-living African striped mice ( Rhabdomys pumilio ) is influenced by ecological factors with a bearing on energy regulation, i.e. food availability, abiotic environmental variation and social tactic. Striped mice typically form extended family groups that huddle together at night, reducing energetic costs of thermoregulation, but solitary individuals also occur in the population. We analysed 2827 blood samples from 1008 individuals of seven different social categories that experienced considerable variation in food supply and abiotic condition. Blood samples were taken from mice in the morning after the overnight fast and before foraging. bBGC increased significantly with food plant abundance and decreased significantly with minimum daily ambient temperature. Solitary striped mice had significantly higher bBGC than group-living striped mice. Our results suggest that adaptive responses of bBGC occur and we found large natural variation, indicating that bBGC spans a far greater homeostatic range than previously thought.

D-Mannose as a Preservative of Glucose in Blood Samples

1992 ◽  
Vol 38 (3) ◽  
pp. 411-413 ◽  
Author(s):  
A Y Chan ◽  
C S Ho ◽  
T Y Chan ◽  
R Swaminathan
Keyword(s):  
Blood Glucose ◽  
Glucose Concentration ◽  
Blood Concentration ◽  
Blood Glucose Concentration ◽  
Blood Samples ◽  
Intracellular Glucose

Abstract We studied the changes in blood glucose concentration in blood samples collected in heparinized specimen tubes containing no other preservative, or containing NaF, D-mannose, or a combination of NaF and D-mannose. Blood concentration in samples taken into NaF decreased by 0.40 mmol/L in the first 2 h; thereafter, there was no change. In samples collected into mannose there was a small but significant decrease in blood glucose concentration with time. When samples containing mannose were analyzed immediately after collection, the concentration of glucose was higher than in later analyses, probably because of an exchange of intracellular glucose for extracellular mannose. When a combination of NaF and mannose was used, the blood glucose concentration was relatively stable but slightly higher than nonpreserved samples for the next 24 h. However, samples containing mannose were unsuitable for electrolyte analysis. We conclude that a combination of D-mannose and NaF may be a better preservative for blood glucose than either compound alone.

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