scholarly journals Cranial Bone Regeneration by Controlled Release of Platelet Growth Factors from Biodegradable Hydrogel

2005 ◽  
Vol 14 (2) ◽  
pp. 288-290 ◽  
Author(s):  
Akishige Hokugo ◽  
Yasunori Sawada ◽  
Kozo Mushimoto ◽  
Shosuke Morita ◽  
Yasuhiko Tabata
Keyword(s):  
Growth Factors ◽  
Controlled Release ◽  
Bone Regeneration ◽  
Cranial Bone ◽  
Biodegradable Hydrogel

Controlled release of platelet growth factors enhances bone regeneration at rabbit calvaria

2007 ◽  
Vol 104 (1) ◽  
pp. 44-48 ◽  
Author(s):  
Akishige Hokugo ◽  
Yasunori Sawada ◽  
Rie Hokugo ◽  
Hiromitsu Iwamura ◽  
Masakiyo Kobuchi ◽  
...  
Keyword(s):  
Growth Factors ◽  
Controlled Release ◽  
Bone Regeneration

In situ controlled release of stromal cell-derived factor-1α and antimiR-138 for on-demand cranial bone regeneration

2018 ◽  
Vol 182 ◽  
pp. 215-224 ◽  
Author(s):  
Guangsheng Wu ◽  
Chao Feng ◽  
Jingjing Quan ◽  
Zhongshan Wang ◽  
Wei Wei ◽  
...  
Keyword(s):  
Controlled Release ◽  
Bone Regeneration ◽  
Stromal Cell ◽  
Cranial Bone ◽  
On Demand ◽  
Stromal Cell Derived Factor

Bone Induction by Controlled Release of BMP-2 from a Biodegradable Hydrogel in Various Animal Species - From Mouse to Non-Human Primate -

2005 ◽  
Vol 288-289 ◽  
pp. 253-256 ◽  
Author(s):  
Masaya Yamamoto ◽  
Yoshitake Takahashi ◽  
Yasuhiko Tabata
Keyword(s):  
Controlled Release ◽  
Bone Regeneration ◽  
Bone Morphogenetic Protein ◽  
Bone Defect ◽  
Animal Species ◽  
Bone Induction ◽  
Morphogenetic Protein ◽  
Biodegradable Hydrogel ◽  
Human Primate ◽  
Hydrogel System

The objective of this study is to examine feasibility of biodegradable gelatin hydrogels incorporating bone morphogenetic protein (BMP)-2 in inducing bone regeneration at a bone defect of non-human primates and rabbits considering their BMP-2 release profiles. As a result, controlled release by the hydrogel system enabled BMP-2 to induce successful bone regeneration in non-human primates even at the BMP-2 dose as low as that for rabbit case (0.034 mg of BMP-2/cm3 of hydrogel).

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