Serum 25-hydroxyvitamin D Levels are Lower in Chronic Rhinosinusitis with Nasal Polyposis and are Correlated with Disease Severity in Taiwanese Patients

2013 ◽  
Vol 27 (6) ◽  
pp. e162-e165 ◽  
Author(s):  
Ling-Feng Wang ◽  
Chih-Hung Lee ◽  
Chen-Yu Chien ◽  
Jeff Yi-Fu Chen ◽  
Feng-Yu Chiang ◽  
...  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Disease Severity ◽  
Nasal Polyposis ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

Serum 25-hydroxyvitamin D levels are lower in urban African American subjects with chronic rhinosinusitis

2008 ◽  
Vol 122 (2) ◽  
pp. 415-417 ◽  
Author(s):  
Jayant M. Pinto ◽  
John Schneider ◽  
Rosanne Perez ◽  
Marcella DeTineo ◽  
Fuad M. Baroody ◽  
...  
Keyword(s):  
African American ◽  
Chronic Rhinosinusitis ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

scholarly journals Vitamin K & D Deficiency Are Independently Associated With Covid-19 Disease Severity

2021 ◽  
Author(s):  
Ankita P Desai ◽  
Sahera Dirajlal-Fargo ◽  
Jared C Durieux ◽  
Heather Tribout ◽  
Danielle Labbato ◽  
...  
Keyword(s):  
Vitamin D ◽  
Disease Severity ◽  
Vitamin K ◽  
Matrix Gla Protein ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
Moderate Disease ◽  
Unit Increase ◽  
The Status ◽  
25 Hydroxyvitamin D

Abstract Background We investigated the status of vitamin K and vitamin D and association to COVID-19 outcomes. Methods Levels of inactive vitamin K-dependent dephosphorylated uncarboxylated matrix Gla protein (dp-ucMGP; marker of vitamin K status) and 25-hydroxyvitamin D levels (25(OH)D; vitamin D status) were measured in plasma samples from participants with confirmed acute COVID-19 and were age and sex matched to healthy controls. Unadjusted (UOR) and adjusted odds ratios (AOR) with 95% confidence intervals (CI) were computed using cumulative logistic regression. Results 150 subjects were included, 100 COVID-19+ and 50 controls. Median agewas 55 (IQR: 48, 63), 50% were females. 34% had mild COVID-19 disease, 51% moderate disease, and 15% severe. Dp-ucMGP levels were higher (i.e. worse K status) in COVID-19+ vs controls (776.5 ng/mL vs 549.8 ng/mL, p <0.0001) with similar 25(OH)D between groups (25.8 vs 21.9 ng/mL, p=0.09). Participants who were vitamin D deficient (<20ng/mL) had the worse vitamin K status (dp-ucMGP >780ng/mL) and experienced the most severe COVID-19 outcomes. In adjusted models, every one-unit increase in the log2 dp-ucMGP nearly doubled the odds of acute critical disease or death [AOR 95%CI: 1.84 (1.01, 3.45)] and every one-unit decrease in the natural log 25(OH)D was associated with more than three times the likelihood of COVID-19 disease severity [AOR 95%CI: 0.29 (0.11, 0.67)]. Conclusion Early in acute COVID-19, both vitamin K and vitamin D deficiency were independently associated with worse COVID-19 disease severity, suggesting a potential synergistic interplay between these two vitamins in COVID-19.

Original publication: Low serum 25‐hydroxyvitamin D (25[OH]D) levels in patients hospitalized with COVID‐19 are associated with greater disease severity

2020 ◽  
Vol 93 (5) ◽  
pp. 629-630 ◽  
Author(s):  
Grigorios Panagiotou ◽  
Su Ann Tee ◽  
Yasir Ihsan ◽  
Waseem Athar ◽  
Gabriella Marchitelli ◽  
...  
Keyword(s):  
Disease Severity ◽  
Original Publication ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Low Serum

Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalised with COVID-19 are associated with greater disease severity

2020 ◽  
Author(s):  
Su Tee ◽  
Grigorios Panagiotou ◽  
Yasir Ihsan ◽  
Waseem Athar ◽  
Gabriella Marchitelli ◽  
...  
Keyword(s):  
Disease Severity ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Low Serum

scholarly journals Low serum 25‐hydroxyvitamin D (25[OH]D) levels in patients hospitalized with COVID‐19 are associated with greater disease severity

2020 ◽  
Vol 93 (4) ◽  
pp. 508-511 ◽  
Author(s):  
Grigorios Panagiotou ◽  
Su Ann Tee ◽  
Yasir Ihsan ◽  
Waseem Athar ◽  
Gabriella Marchitelli ◽  
...  
Keyword(s):  
Disease Severity ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Low Serum
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