scholarly journals Benzo [a] Pyrene- carcinogenic and mutagenic equivalents of fingerlings of Clarias gariepinus (Burchell, 1822) exposed to water soluble fractions of Nigerian Bonny Light crude oil BLCO

2020 ◽  
Vol 3 (1) ◽  
pp. 186-191
Author(s):  
Christopher Onyemaechi Ezike ◽  
Awere Sylvernus U ◽  
Nwosu Callistus
Author(s):  
Abraham, Chiedozie Nicholas ◽  
J. Udom, Godwin ◽  
C. Patrick-Iwuanyanwu, Kingsley

This study evaluated the Nephrotoxic effect of water soluble fraction (WSF) of Bonny Light Crude Oil (BLCO). After preparation of the WSF and a range finding test, the Wistar albino rats were administered three concentrations (25%, 50% and 100%) of WSF of BLCO for 30 and 60days. Data from the study showed that Urea concentration increased significantly (p≤0.05) with increasing dose of BLCO ranging from 14.71 mg/dl in the control to 35.28 mg/dl in the 100% group after 30days and 14.28 mg/dl in the control to 41.08mg/dl in the 100% group after 60days, Creatinine concentration increased significantly (p≤0.05) from 0.22 mg/dl in the control to 0.82mg/dl in the 100% group after 60 days administration while electrolyte (Na, K, Cl) concentration increased significantly (p≤0.05) with increasing dose of BLCO after 60days administration. Histopathological examination of the kidney was characterized by partial partitioning of the glomerular tufts, obliteration of the Bowman’s capsule and distortion of the renal tubules. The findings in this research suggest that WSF of BLCO induced nephrotoxicity.


2021 ◽  
Vol 19 (1) ◽  
pp. 26-33
Author(s):  
B.S. Audu ◽  
M. Damshit ◽  
J.O. Omirinde ◽  
I.A. Wakawa ◽  
Y. Sulaiman ◽  
...  

Waste dry cell batteries are frequently improperly disposed and subsequently washed into water bodies-- causing deleterious effects on fish particularly Clarias gariepinus which inhabits diverse freshwater habitats. Acute toxicity of water-soluble fractions of waste dry cell batteries was investigated on C. gariepinus fingerlings under laboratory conditions in 96 hours. Ten (10) C. gariepinus fingerlings were exposed to acute concentrations (0.31, 0.63, 1.25, 2.50, and 5.00 g/L) of waste dry cell batteries and a control (0.00 g/L), each duplicate replicated. Histopathological alterations  evident in the gills were lamellar fusion, hyperplasia, inter-lamella space occlusion, hypertrophy and erosion of secondary lamellae. The liver showed nuclear and hepatocytes degeneration, vacuolation and portal congestion. Acute concentrations of water-soluble fractions of waste dry cell batteries caused significant (P<0.05) changes in the histomorphology of the gills and liver of C. gariepinus fingerlings, therefore indiscriminate disposal of waste dry cell batteries around riparian ecosystem should be safeguarded to reduce the declining diversity and abundance of freshwater fish species. Keywords: African catfish, 96 hr.LC50, Fingerlings, Histopathology Zinc-carbon battery


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