scholarly journals Resilience of Adolescents Diagnosed with Anxiety and Their Parents in Clinical Sample

2021 ◽  
Vol 4 (1) ◽  
pp. 58
Author(s):  
Krisztina Törő ◽  
Szabolcs Takács ◽  
Gábor Csikós
Keyword(s):  
Anxiety Disorders ◽  
Positive Relationship ◽  
Protective Factor ◽  
Clinical Sample ◽  
Control Group ◽  
Clinical Group ◽  
Psychiatric Problem ◽  
Resilience Scale ◽  
Significant Difference ◽  
Psychological Difficulties

Anxiety disorder is the most frequent psychiatric problem among children and adolescents. Research proved that resilience can be a protective factor in coping with psychological difficulties. Our research focuses on these aspects of resilience. Aims: We aimed to investigate the resilience and anxiety level of families with adolescents who were diagnosed with anxiety disorders. The clinical sample included 40 adolescents who were diagnosed with anxiety disorders and who received ambulant treatment. (18 boys and 22 girls; age: M=13.37 years, SD=1.46). Members of the control group were recruited from schools and they were normally developing adolescents without any psychiatric diagnosis. (18 boys and 19 girls, age: M=13.7 years; SD=1.56) DASS-21, Ten items Connor-Davidson Resilience Scale and self-made demographic sheet were used. Regarding the resilience, a Significant difference was found between the clinical and the sample group both among the mothers and their children. However, in the case of fathers, no discrepancy was found. Our results suggest that there is a significant, moderate positive relationship between the resilience of the mother and their children. Nevertheless, similar mechanisms in the fathers’ case cannot be registered. In the control group, the fathers’ perception of their child’s resilience proved to be the strongest predictive factor (beta=0,495). On the contrary in the clinical group, the maternal perception was more accurate. (beta=0,06). Resilience can serve as a protective factor against anxiety. Our results can be useful for practitioners and draw attention to the importance of intrafamily mechanisms in coping with anxiety and mood disorders.

scholarly journals Resilience of adolescents diagnosed with anxiety and their parents in clinical sample

2020 ◽  
Author(s):  
Krisztina Dr Törő ◽  
Szabolcs Takács ◽  
Gabor Csikos
Keyword(s):  
Anxiety Disorders ◽  
Positive Relationship ◽  
Protective Factor ◽  
Clinical Sample ◽  
Control Group ◽  
Clinical Group ◽  
Psychiatric Problem ◽  
Resilience Scale ◽  
Significant Difference ◽  
Psychological Difficulties

Introduction: Anxiety disorder is the most frequent psychiatric problem among children and adolescents. Research proved that resilience can be a protective factor in coping with psychological difficulties. Our research focuses on these aspects of resilience. Aims: We aimed to investigate the resilience and anxiety level of families with adolescents who were diagnosed with anxiety disorders. Method: The clinical sample included 40 adolescents who were diagnosed with anxiety disorders and who received ambulant treatment. (18 boys and 22 girls; age: M=13.37 years, SD=1.46). Members of the control group were recruited from schools and they were normally developing adolescents without any psychiatric diagnosis. (18 boys and 19 girls, age: M=13.7 years; SD=1.56) DASS-21, Ten items Connor-Davidson Resilience Scale and self-made demographic sheet were used. Results: Regarding the resilience, a Significant difference was found between the clinical and the sample group both among the mothers and their children. However, in the case of fathers, no discrepancy was found. Our results suggest that there is a significant, moderate positive relationship between the resilience of the mother and their children. Nevertheless, similar mechanisms in the fathers’ case cannot be registered. In the control group, the fathers’ perception of their child’s resilience proved to be the strongest predictive factor (beta=0,495). On the contrary in the clinical group, the maternal perception was more accurate. (beta=0,06). Conclusions: Resilience can serve as a protective factor against anxiety. Our results can be useful for practitioners and draw attention to the importance of intrafamily mechanisms in coping with anxiety and mood disorders.

Adolescents’ self-mutilation - Relationship with dependent behaviour

2003 ◽  
Vol 62 (4) ◽  
pp. 241-249 ◽  
Author(s):  
M. Bolognini ◽  
B. Plancherel ◽  
J. Laget ◽  
P. Stéphan ◽  
O. Halfon
Keyword(s):  
Suicide Attempts ◽  
Clinical Sample ◽  
Control Sample ◽  
Clinical Population ◽  
Control Group ◽  
Clinical Group ◽  
Self Mutilation ◽  
Self Harm ◽  
Partial Overlap ◽  
The Relationship

The aim of this study, which was carried out in the French-speacking part of Switzerland, was to examine the relationship between suicide attempts and self-mutilation by adolescents and young adults. The population, aged 14-25 years (N = 308), included a clinical sample of dependent subjects (drug abuse and eating disorders) compared to a control sample. On the basis of the Mini Neuropsychiatric Interview ( Sheehan et al., 1998 ), DSM-IV criteria were used for the inclusion of the clinical population. The results concerning the occurrence of suicide attempts as well as on self-mutilation confirm most of the hypotheses postulated: suicidal attempts and self-mutilation were more common in the clinical group compared to the control group, and there was a correlation between suicide attempts and self-mutilation. However, there was only a partial overlap, attesting that suicide and self-harm might correspond to two different types of behaviour.

scholarly journals The Relationship between Mental Health with the Level of Empathy Among Medical Students in Southern Thailand: A University-Based Cross- Sectional Study

2021 ◽  
Vol 73 (12) ◽  
pp. 832-840
Author(s):  
Katti Sathaporn ◽  
Jarurin Pitanupong
Keyword(s):  
Mental Health ◽  
Medical Students ◽  
Protective Factor ◽  
Cross Sectional Study ◽  
Clinical Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Significant Difference ◽  
High Level

Objective: To determine the level of and factors associated with empathy among medical students.Materials and Methods: This cross-sectional study surveyed all first- to sixth-year medical students at the Facultyof Medicines, Prince of Songkla University, at the end of the 2020 academic year. The questionnaires consisted of:1) The personal and demographic information questionnaire, 2) The Toronto Empathy Questionnaire, and 3) ThaiMental Health Indicator-15. Data were analyzed using descriptive statistics, and factors associated with empathylevel were assessed via chi-square and logistic regression analyses.Results: There were 1010 participants with response rate of 94%. Most of them were female (59%). More than half(54.9%) reported a high level of empathy. There was a statistically significant difference in empathy levels betweenpre-clinical and clinical medical students; in regards to empathy subgroups (P-value < 0.001). The assessment ofemotional states in others by demonstrating appropriate sensitivity behavior, altruism, and empathic respondingscores among the pre-clinical group were higher than those of the clinical group. Multivariate analysis indicatedthat female gender, pre-clinical training level, and minor specialty preference were factors associated with empathylevel. The protective factor that significantly improved the level of empathy was having fair to good mental health.Conclusion: More than half of the surveyed medical students reported a high level of empathy. The protective factorthat improved the level of empathy was good mental health. However, future qualitative methods, longitudinalsurveillance, or long-term follow-up designs are required to ensure the trustworthiness of these findings.

scholarly journals Multiple Gene Polymorphisms Associated with Exfoliation Syndrome in the Uygur Population

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Yi-Nu Ma ◽  
Ting-Yu Xie ◽  
Xue-Yi Chen
Keyword(s):  
Protective Factor ◽  
Lysyl Oxidase ◽  
Direct Sequencing ◽  
Control Group ◽  
Exfoliation Syndrome ◽  
Nucleotide Polymorphisms ◽  
Age And Gender ◽  
Protective Allele ◽  
Significant Difference ◽  
And Gender

Background. Our previous data suggested that three single-nucleotide polymorphisms (SNPs), rs1048661, rs3825942, and rs2165241, of the lysyl oxidase-like 1 gene (LOXL1) are significantly associated with exfoliation syndrome (XFS) and exfoliation glaucoma (XFG). The following study investigated other SNPs that potentially effect XFS/XFG. Methods. A total of 216 Uygur patients diagnosed with XFS/XFG, and 297 Uygur volunteers were admitted to the First Affiliated Hospital at Xinjiang Medical University between January 2015 and October 2017. Blood samples were collected by venipuncture. Alleles and genotypes of LOXL1, TBC1D21, ATXN2, APOE, CLU, AFAP1, TXNRD2, CACNA1A, ABCA1, GAS7, and CNTNAP2 were analyzed by direct sequencing. Results. The allele G of rs41435250 of LOXL1 was a risk allele for XFS/XFG (P<0.001), whereas the allele G of rs893818 of LOXL1 was a protective allele for XFS/XFG (P<0.001). After adjusting all data for age and gender, the following results were obtained: the frequency of genotype CC for rs7137828 of ATXN2 was significantly higher in XFS/XFG patients than in controls (P=0.027), while no significance was found with reference to the frequency of genotype TT. The frequency of genotype GG for rs893818 of LOXL1 (P<0.001) and the frequency of genotype AA were both significantly higher in XFS/XFG groups compared to the control group (P<0.001). In addition, the frequency of genotype TT for rs41435250 of LOXL1 was higher in XFS/XFG patients than in controls (P=0.003), while no significant difference was found with reference to the frequency of genotype GG after adjusting for age and gender. In addition, the haplotypes G-A/T-G/G-G for rs41435250 and rs893818 were significantly associated with XFS/G. Conclusions. With reference to LOXL1, the rs41435250 resulted as a risk factor and rs893818 as a protective factor for XFS/XFG in the Uygur populations. Meanwhile, the rs16958445 of TBC1D21 and the rs7137828 of ATXN2 have also shown to be associated with pathogenesis of XFS/XFG.

scholarly journals Clinical importance of Clostridium difficile finding in hospitalized patients

2008 ◽  
Vol 61 (11-12) ◽  
pp. 632-637 ◽  
Author(s):  
Branislava Kocic ◽  
Predrag Stojanovic
Keyword(s):  
Clostridium Difficile ◽  
Antibiotic Treatment ◽  
Clinical Importance ◽  
Hospitalized Patients ◽  
Control Group ◽  
Clinical Group ◽  
Clinical Center ◽  
Significant Difference ◽  
Clostridium Difficile Toxin ◽  
Stool Samples

Introduction Clostridium difficile infections predominatelly occur among hospitalized patients. The aim of this study was to evaluate the importance of finding the isolate of Clostridium difficile cultured from the stool of hospitalized patients. Material and methods Material consisted of 100 patients with at least one liquid stool samples and control group with form stool. Every patient spent minimum 48h in hospital before the sampling. The material was immediately cultured on mediums for isolation of enteric pathogens, and on selective CCFA medium (Biomedics) for Clostridium difficile in anaerobic condition. Diagnosis of Clostridium difficile toxin in stool samples was achieved by ELISA-RIDASCREEN Clostridium difficile Toxin A/B test (R-Biopharm). Results One-hundred forty one stool samples of patients in Clinical Center Nis were cultivated and examined for C. difficile. The bacteria was isolated in seven patients from the clinical group. In four (57.14%) patients, the presence of C. difficile toxin in stool was established. The bacteria was diagnosed from the stool samples of five patients from the control group, but the toxin was not found in their stool samples. Discussion The results performed at the Institute for Public Health Nis are in accordance with previously published results that all patients with positive findings of Clostridium difficile toxin in stool samples were on antibiotic treatment longer than 14 days. By analyzing the patient's stay in hospital and duration of antibiotic treatment, we observed the statistically significant difference in findings between the patients with CDAD and the patients from the control group with positive bacteria. Conclusion The study confirms the importance of finding Clostridium difficile associated disease in four (4%) hospitalized patients.

Differences in plasma concentration of acylethanolanydes and acylglycerols in paired samples of bipolar patients and first- and second-degree relatives

2016 ◽  
Vol 33 (S1) ◽  
pp. S340-S340
Author(s):  
P. Romero-Sanchiz ◽  
J. Guzman-Parra ◽  
F. Mayoral-Cleríes ◽  
F. Rivas-Guerrero ◽  
P. Araos-Gómez ◽  
...  
Keyword(s):  
Clinical Sample ◽  
Endocannabinoid System ◽  
Bipolar Disorders ◽  
Control Group ◽  
Clinical Group ◽  
Paired Samples ◽  
Close Relationship ◽  
Competing Interest ◽  
Bipolar Patients ◽  
Second Degree

IntroductionEndocannabinoid System (ECS) has been highlighted as one of the most relevant research topics by neurobiologists, pharmacists, basic scientists and clinicians (Skaper and Di Marzo, 2012). Recent work has associated major depressive disorder with the ECS (Ashton and Moore, 2011). Despite the close relationship between depression and bipolar disorders, as far as we know, there is no characterization of ECS and congeners in a sample of patients with bipolar disorders.Aims and objectivesThe objective of this work is to characterize the plasma levels of endocannabinoids and congeners in a sample of patients with bipolar disorders.MethodThe clinical group was composed by 19 patients with a diagnosis of bipolar disorders using SCID-IV (First et al., 1999). The control group was formed by 18 relatives of first- or second-degree of the patients.The following endocannabinoids and congeners were quantified: N-palmitoleoylethanolamide (POEA), N-palmitolylethanolamide (PEA), N-oleoylethanolamide (OEA), N-stearoylethanolamide (SEA), N-arachidonoylethanolamide (AEA), N-dihomo-γ-linolenoylethanolamide (DGLEA), N-docosatetraenoylethanolamide (DEA), N-linoleoylethanolamide (LEA), N-docosahexaenoylethanolamide (DHEA), 2-arachidonoylglycerol (2-AG), 2-linoleoylglycerol (2-LG), and 2-oleoylglycerol (2-OG).ResultsThe result showed statistically significant lower levels of AEA, DEA and DHEA in clinical sample. Previous research also identified lower levels of AEA in depressed women (Hill et al., 2008, 2009). Until date, it is unknown if DEA and DHEA have some effect on EC receptors, and whether they have some direct effects on endocannabinoids.ConclusionsIt would be necessary to carry our other research with a larger sample, which could allow the control of potential confounding variables.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Out-patient triple chronotherapy for the rapid treatment and maintenance of response in depression: feasibility and pilot randomised controlled trial

BJPsych Open ◽  
2021 ◽  
Vol 7 (6) ◽  
Author(s):  
David Veale ◽  
Marc Serfaty ◽  
Clara Humpston ◽  
Andriani Papageorgiou ◽  
Sarah Markham ◽  
...  
Keyword(s):  
Rating Scale ◽  
Clinical Sample ◽  
Controlled Trial ◽  
Bright Light ◽  
Light Therapy ◽  
Control Group ◽  
Intention To Treat ◽  
Significant Difference ◽  
Randomised Controlled ◽  
Rapid Treatment

Background Triple chronotherapy (sleep deprivation for 36 h, followed by 4 days of advancing the time of sleep and daily morning bright-light therapy for 6 months) has demonstrated benefits for the rapid treatment of depressive symptoms in four small controlled trials of in-patients. Aims To test the feasibility of recruitment and delivery of triple chronotherapy for out-patients with depression (ISRCTN17706836; NCT03405493). Method In a single-blind trial, 82 participants were randomised to triple chronotherapy or a control intervention. The primary outcome was the number of participants recruited per month and adherence to the protocol. Secondary outcomes included the 6-item Hamilton Rating Scale for Depression (HRSD-6) at 1 week. Timings of observer ratings were baseline and 1, 2, 4, 8 and 26 weeks after randomisation. Results The triple chronotherapy group stayed awake for the planned 36 h and 89.9% adhered to the plan of phase advance of their sleep over the following 4 days. We achieved our recruitment target (60 participants completed the trial within 13 months). There were no reported adverse side-effects. We found a significant difference between the groups by intention-to-treat analysis for the HRSD-6 at weeks 1, 8 and 26. There was a large effect size of Cohen's d = 0.8 on HRSD-6 score at week 1, increasing to d = 1.30 at week 26. A response (≥50% reduction in symptoms) was achieved by 33.3% in the triple chronotherapy group and 16.2% in the control group. This stayed relatively steady until week 26 (35.9 v. 13.9%). Conclusions Triple chronotherapy produced a significant and rapid benefit after 1 week in out-patients with depression that was sustained at 26 weeks. Cost-effectiveness trials with a larger clinical sample are required.

scholarly journals An Examination of Psychological Resilience and Remembered Parental Care among University Students

2021 ◽  
Vol 7 (2) ◽  
pp. 72
Author(s):  
Ozgur Demirci Seyrek ◽  
Ercümend Ersanlı
Keyword(s):  
Parental Care ◽  
Positive Relationship ◽  
Paternal Care ◽  
Personal Information ◽  
Important Variable ◽  
Psychological Resilience ◽  
Resilience Scale ◽  
Strong Positive Relationship ◽  
Significant Difference

In this study, the aim was to examine the relationship between the psychological resilience and remembered parental care of college students in young adulthood and whether this relationship varies according to gender and perceived socio-economic level. A correlational model was used as a research model. For data collection purposes, ‘‘a personal information form,’’ the “Psychological Resilience Scale for Adults” and the “Parental Bonding Instrument” were used by the researchers. The age range of individuals involved in the study ranged from 18 to 26. The research results were tested with SPSS 21. A strong positive relationship was found between remembered mother and remembered father care, while a moderately positive relationship was found between psychological resilience and remembered mother and father care. One of the findings is that there was a significant difference between the care of mothers and of fathers as remembered by male and by female participants. In addition, the study found that there was a statistically significant difference in the level of remembered maternal care, remembered paternal care, and psychological resilience in terms of perceived socioeconomic level. Based on these results, it can be argued that perceived socioeconomic status, which refers to the perception of the presence of means one possesses, had an impact on the individual’s psychological resilience in a direct proportion. In line with the findings, the significant correlation between remembered mother’s care and remembered father’s care can be shown as a long-term contribution to the positive effect on children of the rapport between mother and father. Alongside the fact that the remembered mother’s and father’s care was an important variable in predicting the factors that affected the psychological resilience of undergraduates, it is noted that democratic, caring and warm paternal attitudes are important, rather than the traditional sex-oriented attitudes. Hence, one can argue that it is of importance that fathers and fathers-to-be have increased awareness of their roles in the long-term development of psychologically resilient youngsters, by means of taking on more responsibilities in childrearing.

scholarly journals A genetic variant in the promoter of lncRNA MALAT1 is related to susceptibility of ischemic stroke

2019 ◽  
Author(s):  
yan wang ◽  
Xi-Xi Gu ◽  
Hua-Tuo Huang ◽  
Chun-Hong Liu ◽  
Gui-Jiang Wei ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Lung Adenocarcinoma ◽  
Protective Factor ◽  
Genetic Variant ◽  
Blood Lipid ◽  
Control Group ◽  
Lipid Levels ◽  
Lncrna Malat1 ◽  
Significant Difference ◽  
Blood Lipid Levels

Abstract Metastasis-associated lung adenocarcinoma transcript-1 (MALAT1) was aberrantly expressed in diverse diseases including ischemic stroke (IS). This study aimed to investigate the association between MALAT1 polymorphism and IS risk. We performed the genotyping of rs600231, rs1194338, rs4102217 and rs591291 in the promoter of MALAT1 by SNPscan method. Quantitative PCR was used to determine the levels of MALAT1 relative expression. We found the rs1194338 C>A variant in MALAT1 promoter was associated with IS risk (AC vs. CC: adjusted OR = 0.623, 95% CI, 0.417-0.932, P = 0.021; AA vs. CC: adjusted OR = 0.474, 95% CI, 0.226-0.991, P = 0.047; AC/AA vs. CC: adjusted OR = 0.596, 95% CI, 0.406-0.874, P = 0.008; A vs. C adjusted OR = 0.658, 95% CI, 0.487-0.890, P = 0.007). The IS patients showed higher expression levels of MALAT1 compared with the control group ( P < 0.05), but patients with AC/AA genotypes of rs1194338 have no significant difference compared to CC genotype ( P > 0.05). In addition, no significant differences were observed in blood lipid levels among SNPs of MALAT1 ( P > 0.05). These results suggest that the rs1194338 AC/AA genotypes may be a protective factor for IS, which mechanism needs to be further explored.

Ghrelin and leptin levels in children with anxiety disorders

2019 ◽  
Vol 32 (10) ◽  
pp. 1043-1047 ◽  
Author(s):  
Sevgi Ozmen ◽  
Asilay Şeker ◽  
Esra Demirci
Keyword(s):  
Anxiety Disorders ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Healthy Children ◽  
State Trait Anxiety Inventory ◽  
Anxiety Group ◽  
Significant Difference ◽  
Important Health ◽  
And Gender ◽  
Serum Ghrelin

Abstract Background Anxiety disorders are common psychiatric disorders in childhood and an important health problem that is associated with the risk of serious mental, educational and economical problems. Researchers have mentioned many different mechanisms in the etiopathology of anxiety disorders. This study aimed to investigate ghrelin and leptin levels in children with anxiety disorders and thus to contribute to the clarification of anxiety in children. Methods Forty-three children aged 6–12 years with a diagnosis of the Anxiety Disorder according to DSM 5 and 21 healthy children age- and gender-matched to the study group were included. All the subjects were assessed with Kiddie Schedule for Affective Disorders and Schizophrenia Present and Lifetime Version (K-SADS-PL) and State-Trait Anxiety Inventory for Children (STAI-C) scale. Blood samples were obtained in the morning and serum ghrelin and leptin levels were measured with enzyme-linked immunosorbent assay (ELISA) kits. Results In the anxiety group the ghrelin levels were higher than the control group (p = 0.037) but there was no significant difference between the leptin levels (p = 0.430). Also, when the girls in the anxiety group and the girls in the control group were compared, ghrelin levels were higher in the anxiety group (p < 0.01). Conclusions These findings suggest that ghrelin may play a significant role in the etiologic mechanisms of anxiety disorders. However, more detailed studies are needed to explain the linkage between anxiety disorders and neuropeptides.

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