scholarly journals Expression III (I): A Cross Cultural Analysis of Ovarian Cancer Patient’s Preferences and Expectations on Physician-Patient Communication and Clinical Management in India and Germany

2021 ◽  
Vol 8 (2) ◽  
Author(s):  
Kar S ◽  
◽  
Alavi S ◽  
Oskay Ozcelik G ◽  
Keller M ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Information Needs ◽  
Economic Status ◽  
Information Source ◽  
Cultural Analysis ◽  
Indian Patients ◽  
Significant Difference ◽  
Physician Patient ◽  
Source Of Information

Background: The information level and expectations of the patients suffering from cancers should be taken as a basis for the treatment decisionmaking process. Nevertheless, there are lacking data in both developing and western countries. The objective of this survey was to identify similarities and differences between patients with ovarian cancer from India and Germany in regard to the information needs and expectations concerning physician-patientcommunication and treatment. Patients and Methods: This study was based on the European survey “Expression III”. The German subgroup was compared to an Indian cohort. The study was conducted in the state of Odisha, India using an English translation of the same questionnaire with 43 items. Results: Overall, 86 Indian patients (median age 52y, range 19-76 y) and 427 German patients (median age 62y, range 26-84y) participated in this survey. The most valuable suggestions made by German patients to improve the treatment of ovarian cancer was ‘the therapy shouldn’t lead to hair loss (49%)’, whereas the Indian patients whished for a treatment of shorter duration (47%). The majority of German (90%) and the Indian (79%) patients consider their treating physician to be most effective and patient-friendly information source. Fear of the future was the most difficult aspect of their illness to handle by both study populations (43% India / 55% Germany). Compared to 46% of German patients, not a single patient in India was involved in a study or clinical trial. Conclusions: The study underlines the key role of the physician as the most relevant source of information for patients in both countries. In spite of a significant difference in the socio-economic status, the expectations from their physicians found to be similar in many aspects.

scholarly journals Role of Farm Women in Sustainable Livelihood Pattern in Context of Information Needs

2019 ◽  
pp. 1-5
Author(s):  
Shashikant Divakar ◽  
Chandan Kumar Panda ◽  
Anil Paswan
Keyword(s):  
Disease Management ◽  
Information Needs ◽  
Information Sources ◽  
Women Farmers ◽  
Farm Women ◽  
Sustainable Livelihood ◽  
Age Group ◽  
Paddy Cultivation ◽  
Source Of Information

This study is to analyze information sources and information needs of women farmers of Banka and Bhagalpur district of Bihar. The research was undertaken for assessment of information needed for young farm women of age group of 18-35 years with respect to kharif paddy cultivation. Useful Information is the pivotal for successful kharif paddy cultivation. In the study area young farm women contribute immensely in kharif paddy cultivation.  Information helps in creating awareness about technologies and mobilize people to use them. It also helps in training people, organizing community and ultimately resulting in the development of the whole nation. Result of the study illustrated that farm women need more information about selling of product, pest control, nursery raising and disease management. The study also revealed that the most preferred source of information was personal localite i.e. Husband, Friend, Relatives and Neighbors and agri-input dealers.

scholarly journals Perilaku Pencarian Informasi Generasi milenial untuk Memenuhi Kebutuhan Informasi Mahasiswa Universitas Negeri Padang

2019 ◽  
Vol 8 (1) ◽  
pp. 562
Author(s):  
Yuni Rahmah ◽  
Elva Rahmah
Keyword(s):  
Search Engine ◽  
Information Search ◽  
Information Seeking ◽  
Millennial Generation ◽  
Information Needs ◽  
Information Source ◽  
The Internet ◽  
State University ◽  
Google Search ◽  
Source Of Information

AbstractIn this paper the language about Millennial Generation Information Search Behavior To Meet Information Needs. This study aims to describe the information seeking behavior of the millennial generation to meet the information needs of this study at the Padang State University. Data were collected through observation and distribution of questionnaires with students of the Indonesian and Regional Languages and Literature Department at Padang State University. Analyzing the data, concluded the following matters. (1). Starting - consists of activities that initiate information seeking activities. In general (100%) determine the topic especially before conducting an information search, in general (90%) conduct information search after discussion or consultation with lecturers, in general (95.23%) know the information needs when attending lectures, (88.4 %) know the information needs specifically, and in general (88%) do information when they are aware of and know the need for information. (2). Chaining - activities following a series of citations, citations or forms of reconciliation between documents with each other. In general (92.8 uses a bibliography to search information, generally (90.4%) use the author's name from the core reference to look for other references in conducting information searches, and in general (92.9%) use subjects from core reference to look for other references (3) Browsing - merawak, looking for, but rather directed, in areas that are considered to have the potential for the information needed.In general (73%) libraries can always meet information needs, in general In general (95.2%) look for information on the internet if the information you are looking for is not found in the printed source of information, (92.8%) generally directly looking for information on the internet if the information you need is not found in the printed source of information, at generally (45.22%) query identification (keywords). (4). Differentiating - sorting, using the features in the information source as a basic reference for checking quality or information content. in general (88%) the internet is the main source of information, in general (92.84%) The source of information printed is still very much needed in fulfilling information needs. (5). Monitoring - monitoring progress by focusing on selected sources. In general (88.09%) looked for the latest information through the internet by searching for the latest articles, in general (78.56%) needed to find the latest information to enrich the reference sources. (6). Extracting - systematically digging in one source to retrieve information that is considered important. In general (90.47 when you need information you often search the search engine (google, yahoo), in general (88.09 often uses a journal database to get information, in general (78.56%) after getting information on the internet , you directly copy the information, in general (76.19%) use the "Google" search engine because it is more relevant than other search engines.Keywords: behavior, millennial generation and information.

scholarly journals Role of Lymphadenectomy During Interval Debulking Surgery Performed After Neoadjuvant Chemotherapy in Patients With Advanced Ovarian Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Minjun He ◽  
Yuerong Lai ◽  
Hongyu Peng ◽  
Chongjie Tong
Keyword(s):  
Ovarian Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Residual Disease ◽  
Advanced Ovarian Cancer ◽  
Progression Free Survival ◽  
Debulking Surgery ◽  
Hazard Ratios ◽  
Significant Difference ◽  
Interval Debulking Surgery

ObjectiveThe role of lymphadenectomy in interval debulking surgery (IDS) performed after neoadjuvant chemotherapy (NACT) in advanced ovarian cancer remains unclear. We aimed to investigate the clinical significance of lymphadenectomy in IDS.MethodsWe retrospectively reviewed and analyzed the data of patients with advanced ovarian cancer who underwent NACT followed by IDS.ResultsIn 303 patients receiving NACT-IDS, lymphadenectomy was performed in 127 (41.9%) patients. One hundred and sixty-three (53.8%) patients achieved no gross residual disease (NGRD), and 69 (22.8%) had residual disease < 1 cm, whereas 71 (23.4%) had residual disease ≥ 1cm. No significant difference in progression-free survival (PFS) and overall survival (OS) was observed between the lymphadenectomy group and the no lymphadenectomy group in patients with NGRD, residual disease < 1 cm, and residual disease ≥ 1 cm, respectively. The proportions of pelvic, para-aortic and distant lymph node recurrence were 7.9% (10/127), 4.7% (6/127) and 5.5% (7/127) in the lymphadenectomy group, compared with 5.7% (10/176, P = 0.448), 4.5% (8/176, P = 0.942) and 5.1% (9/176, P = 0.878), respectively, in no lymphadenectomy group. Multivariate analysis identified residual disease ≥ 1 cm [hazard ratios (HR), 4.094; P = 0.008] and elevated CA125 levels after 3 cycles of adjuvant chemotherapy (HR, 2.883; P = 0.004) were negative predictors for OS.ConclusionLymphadenectomy may have no therapeutic value in patients with advanced ovarian cancer underwent NACT-IDS. Our findings may help to better the therapeutic strategy for advanced ovarian cancer. More clinical trials are warranted to further clarify the real role of lymphadenectomy in IDS.

Lack of Association of Cyp1B1*3 Polymorphism and Ovarian Cancer in a Caucasian Population

2004 ◽  
Vol 19 (2) ◽  
pp. 160-163 ◽  
Author(s):  
E. Cecchin ◽  
A. Russo ◽  
E. Campagnutta ◽  
L. Martella ◽  
G. Toffoli
Keyword(s):  
Ovarian Cancer ◽  
Genomic Dna ◽  
Blood Donors ◽  
Caucasian Population ◽  
Cancer Development ◽  
Carcinogenic Effect ◽  
Significant Difference ◽  
Healthy Female ◽  
Mixed Ethnicity

CYP1B1 is the enzyme with the highest efficiency of conversion of estradiol to 4-hydroxyestradiol in humans. This metabolite has a well-known carcinogenic effect interacting with genomic DNA and has been hypothesized to be partly responsible for the role played by estrogens in ovarian cancer development. A polymorphism has been described for this enzyme causing a Leu to Val substitution in position 432 (CYP1B1*3). The Val432 allele has a higher efficiency of conversion of estradiol to 4-hydroxyestradiol and has been reported to increase the risk of ovarian cancer. A previous study reported a higher, significant prevalence of CYP1B1*3 polymorphism in ovarian cancer patients of mixed ethnicity. The aim of this study was to investigate the role of CYP1B1*3 polymorphism as a risk factor for ovarian cancer in a Caucasian population. The polymorphism frequency was determined in 223 cases of ovarian cancer and compared with that of 280 healthy female blood donors. Genetic analysis was performed on genomic DNA from PBMC and RFLP methods were used for mutation detection. No significant difference between cases and controls was found. These results do not support a favoring role of CYP1B1*3 in ovarian cancer development in our population.

scholarly journals DIOCESAN ARCHPRIESTS’ ANNUAL REPORTS AS A SOURCE OF INFORMATION ABOUT THE VOLOGDA DIOCESE HISTORY OF THE LATE 19TH — EARLY 20TH CENTURIES

2020 ◽  
pp. 51-60
Author(s):  
Е.С. Ульянова
Keyword(s):  
Information Source ◽  
Annual Reports ◽  
Russian Orthodox ◽  
Orthodox Church ◽  
Russian Orthodox Church ◽  
History Of ◽  
Source Of Information

В статье исследуются ежегодные отчеты правящих архиереев о состоянии епархий Святейшему Правительствующему Синоду как важнейший источник по истории Русской православной церкви синодального периода. Цель статьи — структурный анализ ежегодных отчетов вологодских архиереев о состоянии Вологодской епархии во второй половине XIX века. Предпринята попытка на частных примерах оценить информативный потенциал каждого раздела отчета. Делается вывод о ежегодных епархиальных отчетах как достаточно информативном источнике, содержащем ценные и многоплановые сведения о жизнедеятельности Русской православной церкви в епархиях. Ставится вопрос о специфике данного вида источника и о влиянии личности правящего архиерея на содержание отчета. The article investigates annual reports prepared by diocesan archpriests to inform the Holy Synod of the Russian Orthodox Church about diocesan life as an important source of information about history of the Russian Orthodox Church governed by the Holy Synod. The aim of the article is to structurally analyze annual reports prepared by Vologda archpriests in the late 19thcentury. The author of the article attempts to assess the informative potential of various sections of these reports. The author concludes that diocesan archpriests’ annual reports are a rather fruitful source. They contain information about eparchial practices of the Russian Orthodox Church. The article investigates peculiar features of this information source and assesses the role of archpriest’s influence on the content of reports.

scholarly journals Understanding Social Media’s Role in Propagating Falsehood in Conflict Situations: Case of the Cameroon Anglophone Crisis

2019 ◽  
Vol 7 (2) ◽  
pp. 55
Author(s):  
Kingsley Lyonga Ngange ◽  
Moki Stephen Mokondo
Keyword(s):  
Social Media ◽  
Information Needs ◽  
Computer Software ◽  
Information Graphics ◽  
Alternative Source ◽  
Conflict Situations ◽  
Social Media Platforms ◽  
Analyse Data ◽  
Source Of Information

Social media have been welcomed as important tools that contribute to satisfying the daily information needs of citizens in today’s global society. To many, they serve as an open and alternative source of information especially where the conventional media fail to play their role of serving the public’s interest first. Notwithstanding, there have been serious and legitimate concerns about the spread of fake news over social media especially during the 2016 US presidential elections (Allcott & Gentzkow, 2017). This coincided with the Cameroon Anglophone Crisis (CAC) in which the Cameroon government blamed social media users for spreading false information about the crisis to the extent that government shut down the Internet in the two affected Anglophone regions of the country for 93 days in 2017. This article therefore, examines the content of information (graphics, audios, videos, texts) posted on two widely used social media platforms (WhatsApp and Facebook) during the Anglophone Crisis, in order to understand how falsehood is propagated especially during crisis situations. A qualitative approach to analyse data of falsehood during the crisis was used and three major ways were identified through which falsehood was propagated. Principally, social media activists used computer software to distort pictures and superimpose content that depict the messages they wanted to pass across. They also spread rumours using texts, audio clips and distorted videos. The conclusion is that social media have been awash with falsehood in the Cameroon Anglophone Crisis. The major recommendation therefore, is that users of social media should make efforts to verify the authenticity of information obtained from such media before consuming and disseminating to others. The December 2014 Law on Terrorism in Cameroon treats such offences seriously and defaulters are severely punished with heavy jail sentences and fines.

Role of social media in information-seeking behaviour of international students

2016 ◽  
Vol 68 (5) ◽  
pp. 643-666 ◽  
Author(s):  
Suraya Hamid ◽  
Sarah Bukhari ◽  
Sri Devi Ravana ◽  
Azah Anir Norman ◽  
Mohamad Taha Ijab
Keyword(s):  
Social Media ◽  
International Students ◽  
Information Seeking ◽  
Information Needs ◽  
Content Type ◽  
Information Seeking Behaviour ◽  
The Social ◽  
Future Direction ◽  
Source Of Information

Purpose The purpose of this paper is to investigate the information-seeking behaviour of international students in terms of their information needs and to highlight the role of social media. Design/methodology/approach In this paper, a systematic literature survey was conducted in order to investigate information-seeking trends among international students while using social media. As a result, an exhaustive systematic literature review (SLR) was carried out in order to investigate social media as a source for the observation of the behaviours of international students. For this purpose, 71 articles were selected from various well-known sources after an intensive SLR process of searching, filtering and enforcing the inclusion and exclusion criteria. Findings As an outcome of this study, the information-seeking behaviour of international students was highlighted with respect to social media as a source of information. In addition, this research identifies the information needs of the international students and categorizes them by the roles played by the social media in fulfilling the information needs. Practical implications A comparative study that highlighted the dearth of studies which merge the social media and information-seeking behaviour of international students as well as identify the future direction for the researchers and for benefits of international students. Originality/value A detail SLR which highlights the need of shifting the information seeking behaviour from libraries to social media in regard to the new environment for international students.

Prevalence and clinical implications of mismatch repair (MMR) deficiency in unselected non-serous epithelial ovarian cancer (EOC) patients (pts).

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 1521-1521
Author(s):  
Mariana Scaranti ◽  
Krithika Murali ◽  
Cecilia Orbegoso ◽  
Katherine Vroobel ◽  
Susana N. Banerjee ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Endometrial Cancer ◽  
Significant Proportion ◽  
Disease Free Survival ◽  
Figo Stage ◽  
Significant Difference ◽  
Serous Epithelial Ovarian Cancer ◽  
Average Body Mass ◽  
Mixed Histology

1521 Background: It has previously been reported that 6-7% of clear cell (CC) and endometrioid (E) ovarian cancers are MMR deficient (MMRd). The prevalence of MMRd in other histological subtypes and correlation with germline (g) MMR (Lynch Syndrome) mutations in unselected non-serous EOC pts is less clear. MMRd in solid tumors has been associated with enhanced response to immunotherapy, hence knowledge of MMR status has therapeutic and familial implications. We aimed to study the prevalence and implications of MMRd and gMMRd in unselected pts with non-serous EOC. Methods: Routine immunohistochemistry (IHC) was performed for the MMR proteins MLH1, MSH2, MSH6 and PMS2 in all non-serous EOC pts from June 2016; retrospective MMR IHC testing in pts in follow-up was performed. Pts with MMRd tumors were referred for gMMR testing. Results: We analyzed 66 unselected pts with non-serous EOC. Median age was 56.4 years (yrs). The majority had E ovarian cancer (54.5%) followed by CC (25.8%), mixed histology (12.1%), mucinous (4.5%) and mullerian (3%) subtypes. Endometriosis was noted in 45.5% of pts, and 75% were FIGO stage I and II at diagnosis. Seventeen pts (25.8%) had concurrent endometrial cancer, all Grade I. On IHC, 15.2% were MMRd: 5 E, 2 CC, 2 mixed and 1 mullerian-type. Of these, 3 pts (30%) had gMMR mutation, 2/3 did not meet the Revised Bethesda criteria for testing. A lower average body mass index (Kg/m2) was noted in MMRd 25.9 versus 30.1 in MMR proficient (MMRp). Median age at diagnosis was 53.5 yrs in the MMRd and 57.7 yrs in MMRp. A higher frequency of concurrent endometrial cancer was observed on the MMRd group (60%) versus (20%) on MMRp (p = 0.007). No statistically significant difference in overall survival or disease-free survival was observed between the MMRd and MMRp population. Conclusions: Our study has shown a higher prevalence of somatic MMRd in non-serous EOC (15.2%) than in previously published literature with a significant proportion found to carry gMMR mutations (4.5%). These interim findings support the role of universal MMR IHC testing in non-serous EOC regardless of family history. [Table: see text]

scholarly journals The Role of Thrombocytosis as a Prognostic Factor for Epithelial Ovarian Cancer

2021 ◽  
pp. 153-156
Author(s):  
Andrijono ◽  
Heru Prasetyo ◽  
Eka R Gunardi ◽  
Gatot Purwoto ◽  
Hariyono Winarto
Keyword(s):  
Ovarian Cancer ◽  
Overall Survival ◽  
Prognostic Factor ◽  
Epithelial Ovarian Cancer ◽  
Cancer Registry ◽  
Hazard Ratio ◽  
Advanced Stage ◽  
Significant Difference ◽  
Mean Time

Objective: To determine whether thrombocytosis is a prognostic factor for epithelial ovarian cancer and its relationship with 3-year overall survival in epithelial ovarian cancer patients.Methods: This study is a retrospective cohort study using medical record of patients with epithelial ovarian cancer registered in cancer registry of Oncology Division in Obstetrics and Gynecology Department, Dr. Cipto Mangunkusumo National General Hospital from January 2014 - July 2016. Data were collected when subjects were first until diseases outcomes identified in 3 years.Results: : Out of 220 subjects, 132 (60%) were patients with advanced stage epithelial ovarian cancer (stage II/III/IV). 94 (42.7%) subjects had thrombocytosis. Patients with advanced stage of disease had higher risk of having thrombocytosis than the ones with earlier stage (p=0.005; OR=2.329). Correlation between thrombocytosis and 3-year overall survival was known to be insignificant (p=0.555). There was shorter mean time survival between patients with thrombocytosis and the ones without but the there was no significant difference in hazard ratio between the two groups (p  = 0.399).Conclusion :Thrombocytosis is not a prognostic factor in patients with epithelial ovarian cancer. There is also no significant difference of 3-year overall survival between patients with or without thrombocytosis.Keywords: epithelial ovarian carcinoma, prognosis,  thrombocytosis.   Abstrak Tujuan: Membuktikan bahwa trombositosis sebagai faktor prognosis kesintasan pada pasien kanker ovarium jenis epitelial dan hubungannya terhadap kesintasan 3 tahun pasien kanker ovarium  jenis epitelial.Metode: Penelitian ini merupakan studi kohort retrospektif menggunakan data rekam medis pasien kanker ovarium epitelial yang terdaftar pada cancer registry Departemen Obstetri dan Ginekologi Divisi Onkologi Rumah Sakit Cipto Mangunkusumo pada tahun Januari 2014-Juli 2016. Pengamatan dilakukan saat subjek pertama kali didiagnosis akhir pengamatan selama 3 tahun.Hasil: Didapatkan 220 subjek penelitian yang merupakan populasi terjangkau dan memenuhi kriteria inklusi dan eksklusi. Dari 220 subjek penelitian, 132 (60%) dari 220 subjek penelitian merupakan pasien dengan kanker ovarium stadium lanjut (Stadium II/III/IV). Trombositosis didapatkan pada 94 orang subjek penelitian (42,7%). Pasien dengan kanker stadium lanjut memiliki risiko trombositosis yang lebih tinggi dibandingkan subjek pada stadium awal (p=0,005;OR=2,329). Trombositosis secara statistik tidak bermakna pada kesintasan 3 tahun (p=0,555). Terdapat mean time survival yang lebih rendah pada pasien dengan trombositosis tetapi tidak ada perbedaan hazard ratio yang bermakna antara subjek dengan atau tanpa trombositosis (p=0,399).Kesimpulan : Trombositosis bukan merupakan faktor prognostik pada pasien kanker ovarium jenis epitelial dan tidak terdapat hubungan antara trombositosis dan 3 tahun pada pasien dengan kanker ovarium jenis epithelial.Kata kunci: karsinoma ovarium epithelial,  prognosis, trombositosis

scholarly journals A társadalmi struktúra és az oktatás összefüggései a sportiskolák rendszerében

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Karolina Eszter Kovács
Keyword(s):  
Family Background ◽  
Economic Status ◽  
Great Plain ◽  
Regional Level ◽  
Competency Assessment ◽  
The North ◽  
Significant Difference ◽  
The Family ◽  
Background Index

A társadalmi helyzet jelentős szerepet játszik életünkben, így a sportiskolai rendszerben is, különös tekintettel a vizsgálat fókuszában álló köznevelési típusú sportiskolákra. Ezen intézmények célja a sportkarrier támogatása mellett a tanulmányi eredményesség növelése is. Célunk a hazai köznevelési típusú sportiskolákban tanuló diákok szocio-ökonómiai státuszának felmérése. Ehhez a 2016-os Országos Kompetenciamérés 10. évfolyamos tanuló adatbázisát alkalmazva néztük meg a tanulók családi háttérindexét, majd összevetettük az egyéb típusú, nem sportiskolás diákok helyzetével. Eredményeink alapján a sportiskolákban/sporttagozattal rendelkező iskolákban és egyéb iskolákban tanuló diákok családi háttérindexének tekintetében jelentős különbség mutatható ki (p<0,001), habár hasonlóságok is mutatkoztak. Régiós szinten a sportiskolák tekintetében az észak-alföldi és közép-magyarországi régiókban voltak a legalacsonyabb, míg a közép-dunántúli régióban a legmagasabb a családi háttérindex átlaga. A nem sportiskolák esetében az észak-alföldi régióban voltak tapasztalhatóak a legalacsonyabb, míg Budapesten a legmagasabbak a családi háttérindex értékek.The role of social status is significant in our life, including the sports school system, with particular emphasis on educational sports schools which are in the focus of the study. The aim of these institutions is not only to support sports careers but also to improve academic achievement. Our aim is to investigate the socio-economic status of students learning in educational sports schools. For this reason, the National Competency Assessment of 2016 was applied, including the data of the 10th-grade students to investigate their family background index. Then, we compared these data to the characteristics of students learning in other types of schools. Based on our results, there is a significant difference in the family background index of students studying in sports schools and non-sports schools, although similarities have also been found. At the regional level, the average family background index was the lowest in the North Great Plain and Central Hungary, while it was the highest in Central-Transdanubia. In the case of non-sports schools, the family background index values were the lowest in the North Great Plain, while it was the highest in Budapest.

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