Short-Term Effects of Metformin and Diabetic Diet on Cognitive Functions in Newly Diagnosed Type 2 Diabetes Mellitus Patients

2020 ◽  
Vol 4 (3) ◽  
pp. 150-157
Author(s):  
Ceyda TANOĞLU ◽  
Yıldız KAYA ◽  
Ülkü Sibel BENLİ ◽  
Neslihan BAŞÇIL TÜTÜNCÜ
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cognitive Functions ◽  
Newly Diagnosed ◽  
Short Term ◽  
Diabetic Diet ◽  
Short Term Effects

Short-term Effects of Sleeve Gastrectomy on Type 2 Diabetes Mellitus in Severely Obese Subjects

2007 ◽  
Vol 17 (8) ◽  
pp. 1069-1074 ◽  
Author(s):  
J. Vidal ◽  
A. Ibarzabal ◽  
J. Nicolau ◽  
M. Vidov ◽  
S. Delgado ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Sleeve Gastrectomy ◽  
Short Term ◽  
Severely Obese ◽  
Obese Subjects ◽  
Short Term Effects

scholarly journals Short-term continuous subcutaneous insulin infusion decreases the plasma vaspin levels in patients with type 2 diabetes mellitus concomitant with improvement in insulin sensitivity

2011 ◽  
Vol 164 (6) ◽  
pp. 905-910 ◽  
Author(s):  
Ke Li ◽  
Ling Li ◽  
Mengliu Yang ◽  
Hua Liu ◽  
Dongfang Liu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Sensitivity ◽  
Continuous Subcutaneous Insulin Infusion ◽  
Insulin Infusion ◽  
Subcutaneous Insulin ◽  
Newly Diagnosed ◽  
Short Term

ObjectiveTo investigate the effects of short-term continuous subcutaneous insulin infusion (CSII) on plasma vaspin levels in patients with newly diagnosed type 2 diabetes mellitus (T2DM).MethodThirty patients with severe newly diagnosed T2DM, 37 subjects with impaired glucose tolerance (IGT) and 38 gender-, age- and body mass index (BMI)-matched normal GT (NGT) controls participated in the study. The T2DM group was treated with CSII for 2 weeks. Euglycemic–hyperinsulinemic clamps were performed in 16 subjects of the T2DM group. Plasma vaspin concentrations were measured with a commercial ELISA kit. The relationship between plasma vaspin levels and metabolic parameters was also analyzed.ResultsFasting plasma vaspin levels were higher in the T2DM group than in IGT and NGT groups (1.83±0.55 vs 0.51±0.21 vs 0.53±0.24 μg/l, P<0.05), but there was no difference between IGT and NGT groups. In T2DM patients, fasting plasma vaspin concentrations were significantly decreased after CSII treatment for 2 weeks (1.83±0.55 vs 1.19±0.57 μg/l, P<0.05), accompanied by significant amelioration of insulin sensitivity and glucose control. The changes in plasma vaspin levels were positively associated with the amelioration of insulin resistance (IR) shown by the changes in homeostasis model assessment of IR.ConclusionPlasma vaspin level is associated with IR and is significantly reduced following short-term CSII treatment.

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