scholarly journals Autophagy Modulation in Mammarenavirus Infection

2020 ◽  
Vol 4 (4) ◽  
pp. 45-51
Author(s):  
Giovanna Gallo ◽  
Julieta Roldán ◽  
Laura Delgui

Mammarenavirus genus groups viruses causing human haemorrhagic diseases, including the New World (NW) Junín virus (JUNV), and the Old World (OW) viruses Lassa (LASV), among others. The high mortality and morbidity rates associated to pathogenic mammarenaviruses, the absence of vaccines and the constant threat of new emerging species, make these viruses a public health concern in endemic areas. Autophagy is a widely-known intracellular metabolic pathway involved in maintaining the cellular homeostasis in response to several stress conditions.

2019 ◽  
Vol 2 (1) ◽  
pp. 77-78
Author(s):  
Niresh Thapa ◽  
Muna Maharjan

Diabetes is an important public health concern which is increasing rapidly in developing countries. It is challenging to prevent and manage diabetes in a rural setting. The Integrated Diabetic Clinic is comprehensive diabetes care under one roof. Its aim is to provide efficient accessible and affordable comprehensive care. It will make a huge difference in the management of diabetes. This clinic will play a major role in unifying different aspects of health care under one roof and offer the most comprehensive and cost-effective accessible health care to minimize mortality and morbidity associated with diabetes.


2021 ◽  
Vol 11 (2) ◽  
pp. 245-252
Author(s):  
Asmita Samal ◽  
J S Dhadwad ◽  
Varun Tiwari ◽  
Narendran Sairam ◽  
Namrata Chaware ◽  
...  

Isolated systolic hypertension is the most common hemodynamic form of hypertension in the elderly. With a rapidly aging population, the prevalence of hypertension, particularly isolated systolic hypertension, is increasing steadily. Isolated systolic hypertension is associated with substantial mortality and morbidity, particularly of cerebrovascular disease. It is a rapidly growing public health concern and its management continues to remain a challenge to practicing physicians. Recent studies like the Systolic Blood Pressure Intervention Trial (SPRINT) and Heart Outcomes Prevention Evaluation (HOPE)-3 have implications for antihypertensive therapy in general and for the management of isolated systolic hypertension in particular.


2001 ◽  
Vol 71 (3) ◽  
pp. 307-311
Author(s):  
Kamel Earar ◽  
Manuela Arbune ◽  
Carmen Mihaela Dorobat ◽  
Gabriela Gurau ◽  
Iulian Antoniac ◽  
...  

Coronaviruses are ARN viruses with high variability, widespread in nature in many animal species and in humans, which can cause diseases with varying degrees of severity, from mild forms to severe forms, with high mortality. The COVID-19 emergency evolves into a pandemic, being the main public health concern worldwide. The main manifestations are respiratory, pneumonic, but extrarespiratory symptoms may be present. Hygiene measures are the only ways to prevent now, because there is no a vaccine or antiviral treatment approved for use in patients with COVID-19. Several therapeutic strategies are under study for the new SARS-CoV-2.


Author(s):  
Bethan Evans ◽  
Charlotte Cooper

Over the last twenty years or so, fatness, pathologised as overweight and obesity, has been a core public health concern around which has grown a lucrative international weight loss industry. Referred to as a ‘time bomb’ and ‘the terror within’, analogies of ‘war’ circulate around obesity, framing fatness as enemy.2 Religious imagery and cultural and moral ideologies inform medical, popular and policy language with the ‘sins’ of ‘gluttony’ and ‘sloth’, evoked to frame fat people as immoral at worst and unknowledgeable victims at best, and understandings of fatness intersect with gender, class, age, sexuality, disability and race to make some fat bodies more problematically fat than others. As Evans and Colls argue, drawing on Michel Foucault, a combination of medical and moral knowledges produces the powerful ‘obesity truths’ through which fatness is framed as universally abject and pathological. Dominant and medicalised discourses of fatness (as obesity) leave little room for alternative understandings.


2004 ◽  
Vol 8 (32) ◽  
Author(s):  

Resistance to antimicrobials has become a major public health concern, and it has been shown that there is a relationship, albeit complex, between antimicrobial resistance and consumption


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