scholarly journals Pleomorphic adenoma of the breast

Mastology ◽  
2021 ◽  
Vol 31 ◽  
Author(s):  
Marina Sonagli ◽  
Georgia Terra Lustre di Flora ◽  
Tábata Alves Domingos ◽  
Vinicius Felipe Cardona ◽  
Solange Maria Torchia de Carvalho ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Needle Biopsy ◽  
Benign Tumor ◽  
Correct Diagnosis ◽  
Phyllodes Tumor ◽  
Surgical Excision ◽  
Metaplastic Breast Cancer ◽  
Core Needle

Pleomorphic adenoma (PA) is a common tumor of the salivary gland, but rarely occurs in the breast. PA of the breast is a benign tumor that usually presents as a periareolar nodule. Core-needle biopsies may yield misdiagnosis with complex fibroadenoma, phyllodes tumor and metaplastic breast cancer due to the mixture of stromal and epithelial elements. We present a case of PA of the breast suspected after core-needle biopsy, but confirmed after surgical excision. The importance to make a correct diagnosis consists in avoid extensive unnecessary surgery, such as mastectomy, since PA can be treated with local surgical resection.

Myositis ossificans mimicking metaplastic breast cancer on core needle biopsy

2019 ◽  
Vol 93 ◽  
pp. 97-102 ◽  
Author(s):  
Klaus Jürgen Schmitz ◽  
Matthias Losch ◽  
Abbas Agaimy
Keyword(s):  
Breast Cancer ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Myositis Ossificans ◽  
Metaplastic Breast Cancer ◽  
Core Needle

scholarly journals Atypical Ductal Hyperplasia of the Breast on Core Needle Biopsy - Risk of Malignant Upgrade on Surgical Excision.

2021 ◽  
Author(s):  
Tiffany Sin Hui Bong ◽  
Thaddaeus Tan ◽  
Juliana TS Ho ◽  
Puay Hoon Tan ◽  
Wing Sze Lau ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Atypical Ductal Hyperplasia ◽  
Surgical Excision ◽  
Hazard Ratio ◽  
Low Risk ◽  
Good Discrimination ◽  
Core Needle ◽  
Ductal Hyperplasia

Abstract Purpose: Atypical ductal hyperplasia (ADH) is a high risk lesion with an increased risk of developing breast cancer. This study aims to identify factors predictive of malignant upgrade for ADH diagnosed on core needle biopsy (CNB) and to develop a nomogram to facilitate evidence-based decision making.Methods: Retrospective analysis of women with CNB diagnosed ADH at the National Cancer Centre Singapore between 2010 and 2015 was performed. Cox proportional hazards regression was used to identify independent clinical, radiological and histological factors associated with malignant upgrade. A nomogram was constructed and multivariable logistic regression coefficients were used to estimate the predicted probability of upgrade for each factor combination. Combinations with the lowest predicted probabilities (≤5%) were identified as low risk. Model sensitivity, specificity, positive and negative predictive values were assessed.Results: From 2010-2015, 238,122 women underwent screening under the national breast cancer screening programme. 29,564 women were recalled and 5742 CNBs were performed, of which 2686 were performed at NCCS. 88 patients (90 lesions) were diagnosed with ADH. 26 lesions were upgraded to a breast malignancy on excision biopsy. On univariate analysis, presence of a mass on either ultrasound (p= 0.018) or mammogram (p=0.026), presence of mammographic microcalcifications (p=0.047), diffuse microcalcification distribution (p=0.034), mammographic parenchymal density (p=0.008), presence of microcalcifications on biopsy (p=0.037) and three or more separate foci of ADH found on biopsy (p=0.024) were associated with malignant upgrade. Mammographic parenchymal density (Hazard ratio= 0.04, 95% CI 0.005-0.35, p=0.014), presence of a mass on ultrasound (Hazard ratio= 10.50, 95% CI 9.21-25.2, p=0.010) and number of foci of ADH (Hazard ratio = 1.877, 95% CI 1.831-1.920, p=0.002) remained significant on multivariate analysis and were included in the normogram which demonstrated good discrimination with C-statistic of 0.81 [95% CI, 0.74 to 0.88].Conclusion: Our model provides good discrimination of breast cancer risk prediction in patients with ADH on CNB. A subset of women at low risk (<5%) of upgrade to cancer may avoid surgical excision following a core-needle biopsy diagnosis of ADH.

scholarly journals Analysis of the concordance rates between core needle biopsy and surgical excision in patients with breast cancer

2012 ◽  
Vol 58 (5) ◽  
pp. 532-536 ◽  
Author(s):  
Marcos Desidério Ricci ◽  
Carlos Marino Cabral Calvano Filho ◽  
Helio Rubens de Oliveira Filho ◽  
José Roberto Filassi ◽  
José Aristodemo Pinotti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Core Needle

scholarly journals Analysis of the concordance rates between core needle biopsy and surgical excision in patients with breast cancer

2012 ◽  
Vol 58 (5) ◽  
pp. 532-536 ◽  
Author(s):  
Marcos Desidério Ricci ◽  
Carlos Marino Cabral Calvano Filho ◽  
Helio Rubens de Oliveira Filho ◽  
José Roberto Filassi ◽  
José Aristodemo Pinotti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Core Needle

scholarly journals Analysis of the concordance rates between core needle biopsy and surgical excision in patients with breast cancer

2012 ◽  
Vol 58 (5) ◽  
pp. 532-536 ◽  
Author(s):  
Marcos Desidério Ricci ◽  
Carlos Marino Cabral Calvano Filho ◽  
Helio Rubens de Oliveira Filho ◽  
José Roberto Filassi ◽  
José Aristodemo Pinotti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Core Needle

Development of a Management Algorithm for the Diagnosis of Cellular Fibroepithelial Lesions From Core Needle Biopsies

2018 ◽  
Vol 26 (8) ◽  
pp. 684-692 ◽  
Author(s):  
Jaehag Jung ◽  
Eunyoung Kang ◽  
Su Min Chae ◽  
Hyojin Kim ◽  
So Yeon Park ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Scoring System ◽  
Needle Biopsy ◽  
Characteristic Curve ◽  
Phyllodes Tumor ◽  
Surgical Excision ◽  
Multivariate Logistic Regression Model ◽  
Core Needle ◽  
Factors Associated ◽  
Phyllodes Tumors

Purpose. Surgical excision is recommended for complete evaluation of cellular fibroepithelial lesions identified from core needle biopsy. The purpose of this study was to determine factors associated with phyllodes tumor among cellular fibroepithelial lesions from core biopsies and develop a scoring system to predict the risk of phyllodes tumor. Methods. We retrospectively reviewed clinical data of 169 breast lesions that were diagnosed as cellular fibroepithelial lesions from core needle biopsy at the Seoul National University Bundang Hospital between March 2005 and January 2013. The clinical, histopathologic, and radiologic characteristics were compared between phyllodes tumors and fibroadenomas during the final diagnosis after surgical excision. Results. Of the 169 lesions, 17 were observed and 152 were surgically removed. After excision, final pathology revealed 60 (39.5%) fibroadenomas and 92 (60.5%) phyllodes tumors. Multivariate analysis demonstrated that age (≥40 years), stromal overgrowth, and stromal cellularity were independent factors associated with phyllodes tumors. A scoring system was developed based on a multivariate logistic regression model, and the area under the receiver operating characteristic curve was 0.828 (95% confidence interval = 0.763-0.893). Conclusion. The scoring system will help clinicians make appropriate treatment for patients with cellular fibroepithelial lesions on core needle biopsy.

Meta-analysis of the concordance of histological grade of breast cancer between core needle biopsy and surgical excision specimen

2016 ◽  
Vol 103 (6) ◽  
pp. 644-655 ◽  
Author(s):  
F. M. Knuttel ◽  
G. L. G. Menezes ◽  
P. J. van Diest ◽  
A. J. Witkamp ◽  
M. A. A. J. van den Bosch ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Histological Grade ◽  
Meta Analysis ◽  
Surgical Excision ◽  
Core Needle
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