scholarly journals Reply: Flare Phenomenon in O-(2-[18F]-Fluoroethyl)-L-Tyrosine PET After Resection of Gliomas

2020 ◽  
Vol 61 (12) ◽  
pp. 1852-1852
Author(s):  
Christian P. Filss ◽  
Carina Stegmayr ◽  
Philipp Lohmann ◽  
Norbert Galldiks ◽  
Karl-Josef Langen
Keyword(s):  
2021 ◽  
Vol 13 ◽  
pp. 175883592098765
Author(s):  
Vincenza Conteduca ◽  
Giulia Poti ◽  
Paola Caroli ◽  
Sabino Russi ◽  
Nicole Brighi ◽  
...  

Over the years, an increasing proportion of metastatic prostate cancer patients has been found to experience an initial bone flare phenomenon under both standard therapies (androgen deprivation therapy, chemotherapy, radiotherapy, abiraterone, enzalutamide) and novel agents (immunotherapy, bone-targeting radioisotopes). The underlying biological mechanisms of the flare phenomenon are still elusive and need further clarification, particularly in relation to different types of treatment and their treatment response assessment. Flare phenomenon is often underestimated and, in some cases, can negatively affect clinical outcome. In cases with suspected bone flare, the treatment should be continued for a minimum of 12 more weeks before further decisions about efficacy can be taken. Physicians and patients should be aware of this effect to avoid unwarranted anxiety and inadequate early discontinuation of treatment. This review aims at highlighting new evidence on flare phenomenon arising after the introduction of new drugs extending across the biochemical, radiographic and clinical spectrum of the disease.


2002 ◽  
Vol 27 (7) ◽  
pp. 486-489 ◽  
Author(s):  
JULIE LEMIEUX ◽  
JEAN GUIMOND ◽  
FRANCIS LABERGE ◽  
CAROLE ST-PIERRE ◽  
YVON CORMIER

2016 ◽  
Vol 14 (5) ◽  
pp. e529-e533 ◽  
Author(s):  
Giuseppe De Vincentis ◽  
Giulia Anna Follacchio ◽  
Viviana Frantellizzi ◽  
Mauro Liberatore ◽  
Francesco Monteleone ◽  
...  

2005 ◽  
Vol 30 (10) ◽  
pp. 672-673 ◽  
Author(s):  
Yoshifumi Sugawara ◽  
Makoto Kajihara ◽  
Takatoshi Semba ◽  
Takashi Ochi ◽  
Takashi Fujii ◽  
...  

BMJ ◽  
1914 ◽  
Vol 1 (2772) ◽  
pp. 400-401
Author(s):  
R. Ross
Keyword(s):  

Urology ◽  
2001 ◽  
Vol 58 (2) ◽  
pp. 5-9 ◽  
Author(s):  
Glenn J Bubley

2010 ◽  
Vol 38 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Gary J. R. Cook ◽  
Ram Venkitaraman ◽  
Aslam S. Sohaib ◽  
Valerie J. Lewington ◽  
Sue C. Chua ◽  
...  

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