scholarly journals PENGARUH EKSTRAK BAWANG HITAM TERHADAP PENURUNAN KADAR GLUKOSA DARAH PADA MENCIT

2021 ◽  
Vol 4 (1) ◽  
pp. 49
Author(s):  
Pipit Festi W
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Mus Musculus ◽  
T Test ◽  
Control Group ◽  
Control Group Design ◽  
Significance Level ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Reduce Blood Glucose

 Administration of oral hypoglycemic drugs and insulin is one of the most common pharmacological treatments given to people with diabetes mellitus. This treatment is carried out in the long term so that it causes side effects and is carried out continuously so that it will affect the financial condition of the diabetes mellitus patient. The purpose of this study was to determine the effect of black garlic extract on decreasing blood glucose levels in mice (mus musculus). This study uses the design of True Experimental design (pretest-posttest with control group design). The population is mice in Pusvetma Surabaya. Sampling method uses Non Probability Sampling Purposive Sampling type. Samples taken were 30 mice consisting of 15 intervention groups and 15 control groups. Data was collected using observation sheets, then analyzed using Independent sample t test and Dependent sample t test with a significance level of 5 0.05. The results showed: Using the test Independent sample T test obtained a significance value ρ = 0,000  It can be concluded that there is an effect of black onion extract to reduce blood glucose levels in mice. In the paired t-test test in the treatment group showed ρ = 0,000  that there were differences in blood glucose levels before being given extracts of garlic and after being given intervention. It is expected that black garlic can be used as an alternative medicine to reduce blood glucose levels.Keyword : Ekstrak of black garlic, Blood sugar levels, mus musculus

scholarly journals Pengaruh Bimbingan Berpusat Pada Klien Terhadap Kemandirian Pasien Diabetes Mellitus Tipe 2

2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Faridatul Istibsaroh ◽  
Yunita Amilia ◽  
Ahmad Zaini Arif ◽  
Tintin Sukartini ◽  
Ima Nadatien
Keyword(s):  
Diabetes Mellitus ◽  
Sampling Technique ◽  
T Test ◽  
Control Group ◽  
Time Duration ◽  
Control Group Design ◽  
Significance Level ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Post Test

Background: Diabetes Mellitus is a disease characterized by an increase in blood glucose levels which has a risk of long-term or short-term complications. The inability of the community to carry out treatment independently is one of the causes that affect the ability of Diabetes Mellitus sufferers to carry out activities. Objective: This study aims to analyze the effect of client-centered guidance on independence in Diabetes Mellitus patients.Methods:This study used a quasy-experimental design with a pre-post test control group design approach, The sample in this study was 46 respondents divided into 23 interventions group and 23 control groups. The sampling technique is consecutive sampling. The intervention was given by providing client-centered guidance on day 1 with 4 stages, time duration ± 60 minutes, and evaluation for 7 days. Analysis of data using an independent t-test with a significance level of = 0.05.Results: The results of the t-test independent t-test with the value of P = 0.001, it means is an effect of client-centered guidance on the independence of Diabetes Mellitus patients.Conclusion: Providing client-centered guidance can increase independence and it can as part of nursing care interventions in the form of a support education system.

scholarly journals The Potential of Noni (Moringa citrifolia) in Lowering Blood Glucose Levels in Diabetes Mellitus Patients

BIOEDUSCIENCE ◽  
2020 ◽  
Vol 4 (2) ◽  
pp. 120-123
Author(s):  
Putri Dafriani ◽  
Mutiara Karamika ◽  
Siska Sakti Anggraini ◽  
Roza Marlinda
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Intervention Group ◽  
Control Group ◽  
Diabetic Patients ◽  
Test Results ◽  
Glucose Levels ◽  
Glucose Testing ◽  
Blood Glucose Levels ◽  
Reduce Blood Glucose

Background: Diabetes Mellitus is a chronic metabolic disorder caused by insulin resistance. Noni juice has the potential as herbal medicine which believed to reduce blood glucose levels. This study aims to determine the effect of noni juice on blood sugar levels on diabetic patients. Methods: This study used 16 respondents. They divided two groups, a control group and a treatment group. Each group consists of 8 respondents. The intervention group received 150 ml of noni juice which was given once a day for ten days. Glucose testing was carried out by the glucose-check method. The blood was taken from the respondent's fingertips capillary. The blood glucose levels between the control group and the intervention group were analyzed using independent t-test. Results: The average blood glucose level in the intervention group was 199.88 mg/dl, while the control group was 326.25 mg/dl. The test results of the mean blood glucose levels between the control group and the intervention group had a significant difference with a value of p = 0.003 (p ≤ 0.05). This indicates a significant effect between blood glucose levels in the control group and the intervention group. Conclusion: Noni can reduce blood glucose levels because it contains flavonoid. It has a hypoglycemic effect. Health workers can suggest consuming noni juice to decrease blood glucose in diabetic patients.    

scholarly journals Self Instructional Training Methods to Reduce Blood Glucose Levels Type 2 Diabetes Mellitus

2017 ◽  
Vol 4 (1) ◽  
pp. 006-011
Author(s):  
Nian Afrian Nuari
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
T Test ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Number Of Patients ◽  
Patients With Diabetes ◽  
Reduce Blood Glucose ◽  
Instructional Training ◽  
Paired T Test

Blood glucose levels  uncontrolled is a problem that is often found in patients with Diabetes Mellitus. This has an impact on the health of the patient as it would appear some macrovascular and microvascular complications. Number of patients with DM in Indonesia has increased every year and only 50% of patients suffering from diabetes who are aware of, and around 30% of them take medication regularly. The purpose of this study to determine the effect of Self Instructional Training method on blood glucose levels of patients. The method used is pre experiment with purposive sampling technique and the sample size of 16 respondents. Measuring instrument used glucometers to measure blood glucose levels and analyzed with Paired T Test. Based on the results, the entire blood glucose levels before the intervention above 200 mg /dl. After Self Instructional Training Intervention average blood glucose level was 35.75 mg /dl. Blood glucose levels are highest when the post test was 253 mg /dl and the lowest is 197 mg /dl. Based on Paired T Test  analysis obtained Self Instructional Training interventions can reduce blood glucose levels of patients with Diabetes Mellitus Type II (p value = 0.000). Diabetes Mellitus patients expected to be able to apply the  SIT method to perform self-care so that the patient's blood glucose levels can be controlled. Patient can do this methods  at home and needed support from their  family and health professionals to treat the diseases.Keywords : Self, Instructional, Training, level, glucose, blood, DM

scholarly journals The Effectiveness of Vitamin C Addition to Blood Glucose Levels of Hyperglycemic Mice with Glimepiride Treatment

2020 ◽  
Vol 6 (3) ◽  
pp. 149
Author(s):  
Indi Kamilia Fitri ◽  
Cholis Abrori ◽  
Dion Krismashogi Dharmawan
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Vitamin C ◽  
Pharmacological Therapy ◽  
Control Group ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Induction Group ◽  
Reduce Blood Glucose

In people with diabetes mellitus (DM) there is a decrease in basal vitamin C levels which is thought to be a result of oxidative stress in the condition of hyperglycemia that it needs to increase vitamin C as an antioxidant. Hyperglycemia in DM needs to be lowered by pharmacological therapy, named glimepirid so the purpose of this study is to determine the effectiveness of vitamin C addition to the reduction of KGD hyperglycemic mice with glimepirid treatment. This study is true experimental with a sample of 25 mice 20-30 grams and divided into five groups, first the control group (K0); STZ  induction group (K1); STZ induction group with glimepirid treatment (K2); STZ induction group with the treatment of vitamin C (K3); STZ induction group by treatment of a combination of glimepirid and vitamin C (K4). STZ is injected intraperitonially 150 mg / kgBB. All groups were measured for KGD 1 after induction of STZ and KGD 2 after treatment for fourteen days. The results of the STZ induction group with the treatment of a combination of glimepirid and vitamin C (K4) experienced a smaller and not significant decrease in BSL in the STZ induction group with a single glimepirid (K2) treatment. These results are thought to have an influence from interactions between drugs that cause one drug to not work optimally. The conclusion of this study is that administration of glimepirid, vitamin C, or both can reduce blood glucose levels in hyperglycemic mice with the greatest decrease occurring in the glimepirid group.

scholarly journals METODE SELF INSTRUCTIONAL TRAINING UNTUK MENURUNKAN KADAR GULA DARAH PASIEN DM TIPE 2 (Self Instructional Training Methods to Reduce Blood Glucose Levels Type 2 Diabetes Mellitus)

2018 ◽  
Vol 21 (4) ◽  
Author(s):  
Erni Setiyorini
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
T Test ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Number Of Patients ◽  
Patients With Diabetes ◽  
Reduce Blood Glucose ◽  
Instructional Training ◽  
Paired T Test

Abstract: Uncontrolled blood glucose levels is a problem that is often found in patients with Diabetes Mellitus. This condition has an impact on the health of the patient as it would appear some macrovascular and microvascular complications. The number of patients with DM in Indonesia has increased by years and only 50% of patients suffering from diabetes who are aware of, and around 30% of them take medication regularly. The purpose of this study was to determine the effectiveness of Self Instructional Training method on blood glucose levels of the patients. The method used pre-experimental design with purposive sampling technique and 16 respondents as the sample. The measuring instrument used glucometers to measure blood glucose levels and analyzed with Paired T Test. Based on the results, the entire blood glucose levels before the intervention above 200 mg /dl. After having Self Instructional Training Intervention, the average blood glucose level was 35.75 mg /dl. The highest blood glucose levels was in the post test as 253 mg /dl and the lowest was 197 mg /dl. Based on Paired T Test  analysis obtained Self Instructional Training interventions could reduce blood glucose levels of patients with Diabetes Mellitus Type II (p value = 0.000). Diabetes Mellitus patients were expected to be able to apply the  SIT method to perform self-care so that the patient's blood glucose levels can be controlled. Patient could do this methods  at home and should be supported by their  family and health professionals to treat the diseases. 

scholarly journals Pengaruh Progresive Muscle Relaxation Terhadap Penurunan Kadar Glukosa Darah Pada Penderita Diabetes Melitus Di Wilayah Kerja Puskesmas Ogan Lima Kecamatan Abung Barat Lampung Utara

2021 ◽  
Vol 3 (2) ◽  
pp. 285-295
Author(s):  
Umi Romayati Keswara ◽  
Rahma Elliya ◽  
Maya Maya
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Muscle Relaxation ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Test Results ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Diabetes Melitus

ABSTRACT: THE EFFECT OF PROGRESIVE MUSCLE RELAXATION (PMR) ON REDUCING BLOOD GLUCOSE LEVELS IN PEOPLE WITH DIABETES MELLITUS IN THE WORK AREA OF OGAN LIMA HEALTH CENTER, WEST ABUNG DISTRICT, NORTH LAMPUNG Introduction: Diabetes mellitus (DM) is a non-communicable disease that often suffers. Diabetes mellitus (DM) is a non-communicable disease that often suffers.Purpose: To determine the effect of progresive muscle relaxation (PMR) on reducing blood glucose levels in people with diabetes mellitus.Method: This type of research is quantitative, quasi-experimental design using non equivalent control groups. The population in this study were all DM patients in the Work Area of Ogan Lima Health Center, West Abung District, North Lampung, with a total sample of 34 respondents. Data analysis used T test analysis (dependent and independent sample t-test).Results: The results of univariate analysis showed that the average blood glucose level of respondents in the pretest group was 247.29 ± 28.431 mg / dL and posttest 210.29 ± 28.711 mg / dL. The average level of respondent's blood glucose at pretest was 255.94 ± 30.738 mg / dL and posttest 230.76 ± 25.69 mg / dL. T-dependent test results obtained by the treatment group p-value = 0,000, and the control group p-value = 0.006. T-independent test results obtained p-value = 0.035.Conclusion: There was a significant difference between the blood glucose levels of diabetics in the treatment group and the control group. Suggestions are expected that health workers can apply PMR training as an alternative therapy for DM patients. Keywords :progresive muscle relaxation, blood glucose level, diabetes mellitus  Latar Belakang: Diabetes Melitus (DM) merupakan penyakit tidak menular yang sering diderita. Data di dunia sebanyak 422 juta orang dewasa hidup dengan diabetes, di Indonesia tahun 2018 prevalensi  diabetes meningkat dari 1,1% menjadi 2,0%, di Provinsi Lampung meningkat dari 0,8% menjadi1,6%, di Kabupaten Lampung Utara meningkat dari 0,9menjadi 1,07 %. Terapi komplementer untuk mengontrol kadar glukosa darah salah satunya dengan relaksasi otot progresif (Progresive Muscle Relaxation (PMR).Tujuan:Diketahui Pengaruh Progresive Muscle Relaxation (PMR) terhadap penurunan kadar glukosa  darah pada penderita diabetes melitus.Metode Penelitian:Jenis penelitian ini adalah kuantitatif, rancangan quasi eksperiment menggunakan non equivalent control group. Populasi dalam penelitian ini adalah seluruh pasien DM di Wilayah Kerja Puskesmas Ogan Lima Kecamatan Abung Barat Lampung Utara, dengan jumlah sampel sebanyak 34 responden.Analisis data menggunakan analisis uji T (dependent dan independent sample t-test).Hasil Penelitian: Hasil analisis univariat bahwa rata-rata kadar glukosa darah responden kelompok perlakuan saat pretest yaitu 247,29 ± 28,431 mg/dL dan posttest 210,29 ± 28,711 mg/dL. Rata-rata kadar glukosa darah responden saat pretest yaitu 255,94 ± 30,738 mg/dL dan posttest 230,76 ± 25,69mg/dL. Hasil uji t-dependen kelompok perlakuan diperoleh p-value=0,000, dan kelompok kontrol p-value=0,006. Hasil uji t-independen diperoleh p-value=0,035.Kesimpulan: Ada perbedaan yang signifikan antara kadar glukosa darah penderita diabetes melitus pada kelompok perlakuan dan kelompok kontrol. Saran diharapkan agar tenaga kesehatan dapat menerapkan latihan PMR sebagai alternative terapi pada pasien DM. Kata Kunci     : progresive muscle relaxation, kadar glukosa darah, diabetes melitus

scholarly journals Pengaruh Progresive Muscle Relaxation Terhadap Penurunan Kadar Glukosa Darah Pada Penderita Diabetes Melitus Di Wilayah Kerja Puskesmas Ogan Lima Kecamatan Abung Barat Lampung Utara

2021 ◽  
Vol 3 (2) ◽  
pp. 285-295
Author(s):  
Umi Romayati Keswara ◽  
Rahma Elliya ◽  
Maya Maya
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Muscle Relaxation ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Test Results ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Diabetes Melitus

ABSTRACT: THE EFFECT OF PROGRESIVE MUSCLE RELAXATION (PMR) ON REDUCING BLOOD GLUCOSE LEVELS IN PEOPLE WITH DIABETES MELLITUS IN THE WORK AREA OF OGAN LIMA HEALTH CENTER, WEST ABUNG DISTRICT, NORTH LAMPUNG Introduction: Diabetes mellitus (DM) is a non-communicable disease that often suffers. Diabetes mellitus (DM) is a non-communicable disease that often suffers.Purpose: To determine the effect of progresive muscle relaxation (PMR) on reducing blood glucose levels in people with diabetes mellitus.Method: This type of research is quantitative, quasi-experimental design using non equivalent control groups. The population in this study were all DM patients in the Work Area of Ogan Lima Health Center, West Abung District, North Lampung, with a total sample of 34 respondents. Data analysis used T test analysis (dependent and independent sample t-test).Results: The results of univariate analysis showed that the average blood glucose level of respondents in the pretest group was 247.29 ± 28.431 mg / dL and posttest 210.29 ± 28.711 mg / dL. The average level of respondent's blood glucose at pretest was 255.94 ± 30.738 mg / dL and posttest 230.76 ± 25.69 mg / dL. T-dependent test results obtained by the treatment group p-value = 0,000, and the control group p-value = 0.006. T-independent test results obtained p-value = 0.035.Conclusion: There was a significant difference between the blood glucose levels of diabetics in the treatment group and the control group. Suggestions are expected that health workers can apply PMR training as an alternative therapy for DM patients. Keywords :progresive muscle relaxation, blood glucose level, diabetes mellitus  Latar Belakang: Diabetes Melitus (DM) merupakan penyakit tidak menular yang sering diderita. Data di dunia sebanyak 422 juta orang dewasa hidup dengan diabetes, di Indonesia tahun 2018 prevalensi  diabetes meningkat dari 1,1% menjadi 2,0%, di Provinsi Lampung meningkat dari 0,8% menjadi1,6%, di Kabupaten Lampung Utara meningkat dari 0,9menjadi 1,07 %. Terapi komplementer untuk mengontrol kadar glukosa darah salah satunya dengan relaksasi otot progresif (Progresive Muscle Relaxation (PMR).Tujuan:Diketahui Pengaruh Progresive Muscle Relaxation (PMR) terhadap penurunan kadar glukosa  darah pada penderita diabetes melitus.Metode Penelitian:Jenis penelitian ini adalah kuantitatif, rancangan quasi eksperiment menggunakan non equivalent control group. Populasi dalam penelitian ini adalah seluruh pasien DM di Wilayah Kerja Puskesmas Ogan Lima Kecamatan Abung Barat Lampung Utara, dengan jumlah sampel sebanyak 34 responden.Analisis data menggunakan analisis uji T (dependent dan independent sample t-test).Hasil Penelitian: Hasil analisis univariat bahwa rata-rata kadar glukosa darah responden kelompok perlakuan saat pretest yaitu 247,29 ± 28,431 mg/dL dan posttest 210,29 ± 28,711 mg/dL. Rata-rata kadar glukosa darah responden saat pretest yaitu 255,94 ± 30,738 mg/dL dan posttest 230,76 ± 25,69mg/dL. Hasil uji t-dependen kelompok perlakuan diperoleh p-value=0,000, dan kelompok kontrol p-value=0,006. Hasil uji t-independen diperoleh p-value=0,035.Kesimpulan: Ada perbedaan yang signifikan antara kadar glukosa darah penderita diabetes melitus pada kelompok perlakuan dan kelompok kontrol. Saran diharapkan agar tenaga kesehatan dapat menerapkan latihan PMR sebagai alternative terapi pada pasien DM. Kata Kunci     : progresive muscle relaxation, kadar glukosa darah, diabetes melitus

scholarly journals The Effectiveness of Vitamin D Addition to Decreasing Blood Glucose Levels of Hyperglycemic Mice Model with Glimepirid Therapy

2020 ◽  
Vol 6 (2) ◽  
pp. 71
Author(s):  
Tsintani Nur Aristiana ◽  
Cholis Abrori ◽  
Muhammad Ali Shodikin
Keyword(s):  
Diabetes Mellitus ◽  
Vitamin D ◽  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Negative Control ◽  
Control Group ◽  
Mice Model ◽  
Control Group Design ◽  
Glucose Levels ◽  
Blood Glucose Levels

Abstract Low 25-hydrocyvitamin D (25(OH)D3) levels are usually found in patients with type 1 and type 2 diabetes mellitus. This study aims to compare the effectiveness of fasting blood glucose levels in hyperglycemic mice model with glimepirid single therapy, hyperglycemic mice model with vitamin D, and mice model of hyperglycemic with glimepirid therapy plus vitamin D. This study used the true experimental research design with the randomized posttest only control group design. There were 25 male mice (Mus musculus) strain Balb/C with 20-30 g body weight and 2-3 months old which were grouped into 5 groups. The negative control group (K1) was injected with placebo and the positive control group (K2) was injected with STZ 150 mg/kgBW i.p. Groups P1, P2, and P3 were given STZ injection of 150 mg/kgBW i.p and given glimepirid 0.26 mg/kgBW; vitamin D 6,5 ml/kgBW; glimepirid 0,26 mg/kgBW with vitamin D supplementation 6,5 ml/kgBW. The results of the Tukey post hoc tests obtained differences in the mean of delta KGD between groups P1 and K2 = 122,55; in group P2 with K2 = 81,60; and in group P3 with K2 = 74,40. From these data, it can be concluded that in the group given glimepirid plus vitamin D there was no additional effectiveness in decreasing fasting blood glucose levels of hyperglycemic mice model compared to the group given only glimepirid therapy and the group given vitamin D alone. Keywords: diabetes mellitus, vitamin D, glimepiride, streptozotocin.

scholarly journals Efektivitas Ekstrak daun Sirih Merah (Piper crocatum Ruiz & Pav.) terhadap Kadar Glutation Peroksidase dan Kadar Glukosa Darah Tikus Jantan Hiperglikemik

Life Science ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 86-94 ◽  
Author(s):  
Syahrizal Ramadhan ◽  
Retno Sri Iswari ◽  
Aditya Marianti
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Wistar Rat ◽  
Male Rats ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Diabetes Melitus

Diabetes mellitus (DM) is a group of metabolic diseases with characteristics of hyperglycemia that occur due to abnormal insulin secretion, insulin action, or both. In diabetes mellitus, it is very easy to occur the formation of excess free radicals which later can cause damage to the pancreas. The body is normally protected from oxidative stress by antioxidants such as superoxide dismutase (SOD), catalase (H2O2 oxidoreductase), and glutathione peroxidase (GPx). This research is an experimental study with posttest control group design. 25 Wistar strain male rats were divided into five treatment groups (positive control given glibenclamide drug 0.09 mg/200 gBB, a negative control was not treated, and red betel leaf extract treatment dose 100, 200, and 400 mg/kg BB). The research procedure included the conditioning of hyperglycemic with alloxan induction of 120 mg/kgBB, extraction of red betel using maceration method with 70% ethanol solvent, treatment by giving the red betel leaves extract orally for 28 days and measure the value of blood glucose and GPx using spectrophotometric methods. The research data was analyzed using one way ANOVA and linear regression. The red betel leaves extract that given to the male Wistar Rat for 28 days gave a significant effect on the value of blood glucose and GPx. The effect given by red betel leaves on blood glucose levels is 4.9%While the effect given by red betel leaves on GPx levels is 91.1%. The conclusion of this research is red betel leaves extract that given to the male Wistar Rat for 28 days gave a significant effect on the value of blood glucose and GPx. The dosage of 400 mg/kgBB is an effective dose in reducing blood glucose levels and increasing GPx levels   Diabetes melitus (DM) merupakan suatu kelompok penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin, atau keduanya. Diabetes melitus   mudah   sekali   terjadi pembentukan   radikal   bebas   berlebih   yang nantinya   dapat meyebabkan kerusakan pada pankreas. Tubuh dalam keadaan normal terlindungi dari stres oksidatif oleh antioksidan seperti superoksida dismutase (SOD), katalase (H2O2 oksidoreduktase), dan glutation peroksidase (GPx). Penelitian ini merupakan penelitian eksperimental dengan posttest control group design. Sebanyak 25 ekor tikus jantan strain Wistar dibagi dalam lima kelompok perlakuan (kontrol posistif diberi obat glibenklamid 0,09 mg/200 gBB, kontrol negatif tidak diberi perlakuan, dan perlakuan ekstrak daun sirih merah dosis 100, 200, dan 400 mg/kg BB). Prosedur penelitian meliputi pengkondisisan hiperglikemik dengan induksi aloksan 120 mg/kgBB, ekstraksi daun sirih merah menggunakan metode maserasi dengan pelarut etanol 70%, perlakuan dengan pemberian ekstrak daun sirih merah secara oral selama 28 hari, serta pengukuran kadar glukosa darah dan kadar GPx dengan metode spektrofotometri. Analisis data menggunakan teknik oneway ANOVA dan regresi linier. Hasil penelitian menunjukkan bahwa pemberian ekstrak daun sirih merah berpengaruh signifikan pada kadar glukosa dan kadar GPx setelah 28 hari perlakuan. Pengaruh yang diberikan daun sirih merah terhadap kadar glukosa darah adalah sebesar 4,9%, sedangkan pengaruh yang diberikan daun sirih merah terhadap kadar GPx adalah sebesar 91,1%. Simpulan dari penelitian ini adalah pemberian ekstrak daun sirih merah pada tikus jantan hiperglikemik secara oral selama 28 hari berpengaruh terhadap kadar glukosa darah dan kadar GPx. Dosis 400 mg/kgBB merupakan dosis efektif dalam menurunkan kadar glukosa darah dan menaikkan kadar GPx.

scholarly journals Konseling Gizi, Kualitas Diit Berbasis Pangan Lokal Dengan Kadar Glukosa Darah Penderita Diabetes Mellitus Tipe Ii Di Wilayah Kerja Puskesmas Bahu

Jurnal GIZIDO ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 108-112
Author(s):  
Rivolta G,M, Walalangi ◽  
Muksin Pasambuna ◽  
Rudolf B. Purba ◽  
Agung Suryohadi
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Local Food ◽  
T Test ◽  
The Body ◽  
Significance Level ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Significant Difference ◽  
Before And After

Diabetes Mellitus is a group of chronic disease which is characterized by increased levels of glucose in the blood due to disorders of the body's metabolism system, in which the pancreas organ incapable of producing the hormone insulin according to needs of the body. Nutritional counselling with quality local food based diit can help control blood glucose levels. This research aims to identify the difference in blood glucose levels and the value of quality diit type II diabetes mellitus patients before and after given nutritional counseling with quality local food based diit. This type of research is Pre Experimental research using one group pretest-posttest design. The number of samples is determined by purposive sampling counted 31 people. Data analysis using Wilcoxon and T-test analysis. The Wilcoxon analysis with significance level of 95% can be seen to produce significant difference in pre-post glycemic index component with p=0,000 (p<0,05) and diversity of pre-post food with p=0,002 (p<0,05). In the result of T-test for pre-post blood glucose variable, there was no significant difference p=0,105 (p>0,05). However, there was a range of decreased glucose levels before and after in 22 respondents with an average decrease of 11.42 mg/dL. Conclusion there was no difference of blood glucose level before and after nutrition counseling with quality of diet based on local food.

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