scholarly journals Faktor resiko kadar kolesterol darah pada pasien rawat jalan penderita jantung koroner di RSUD Meuraxa

2018 ◽  
Vol 3 (2) ◽  
pp. 132
Author(s):  
Nunung Sri Mulyani ◽  
Agus Hendra Al Rahmad ◽  
Raudatul Jannah
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Nutritional Status ◽  
Total Cholesterol ◽  
Significant Relationship ◽  
Coffee Consumption ◽  
Case Control ◽  
Blood Cholesterol ◽  
Chi Square ◽  
Cholesterol Levels

Coronary heart disease generally occurs due to an increase in irregular cholesterol levels. Blood cholesterol is influenced by several factors, including genetic, gender, diet, obesity, and excessive coffee drinking. This study aims to determine the factors that influence blood cholesterol levels in outpatients with coronary heart disease at Meuraxa Regional Hospital. This study is a descriptive-analytical Case Control design, conducted in patients with coronary heart disease as many as 45 cases and 45 controls in May 2017 Data analysis using Chi-Square test. Diet data was collected using food recall, genetic data, sex collected by interview using questionnaires, nutritional status data collected through body mass index (BMI) measurements and cholesterol data collected through blood tests. Bivariate analysis showed a significant relationship between coffee consumption and total cholesterol levels with OR 2.768 (p = 0.033). There was no significant relationship between coffee consumption with HDL, LDL, and triglycerides (0.292; 0.088; 0.125). There was no significant correlation between genetic, gender, diet and nutritional status with levels of total cholesterol, LDL, HDL, and Triglycerides.T here is a significant relationship between coffee consumption and total cholesterol levels in patients with coronary heart disease, so it is necessary to limit coffee consumption for people with coronary heart disease.Penyakit jantung koroner umumnya terjadi karena peningkatan kadar kolesterol yang tidak teratur. Kolesterol darah dipengaruhi oleh beberapa faktor, diantaranya genetik, jenis kelamin, pola makan, obesitas, serta minum kopi yang berlebihan. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi kadar kolesterol darah pada pasien rawat jalan penderita jantung koroner di RSUD Meuraxa. Penelitian deskriptif analitik berdesain Case Control, yang dilakukan pada  pasien penderita jantung koroner sebanyak 45 kasus dan 45 kontrol pada bulan Mei 2017. Analisis data menggunakan uji Chi-Square. Data pola makan dikumpulkan dengan menggunakan food recall, data genetik, jenis kelamin dikumpulkan dengan wawancara menggunakan kuisioner, data status gizi dikumpulkan melalui pengukuran indeks massa tubuh (IMT) dan data kolesterol dikumpulkan melalui pemeriksaan darah. Analisis bivariat  menunjukkan ada hubunganyang signifika konsumsi kopi dengan kadar kolesterol total dengan OR 2,768 (p= 0,033). Tidak ada hubungan yang signifikan konsumsi kopi dengan HDL, LDL dan trigliserida (0,292; 0,088; 0,125). Tidak ada hubungan yang signifikan genetik, jenis kelamin, pola makan dan status gizi dengan kadar kolesterol total, LDL, HDL dan Trgliserida. Ada hubungan yang signifikan konsumsi kopi dengan kadar kolesterol total pada penderita jantung koroner sehingga perlu kiranya pembatasan konsumsi kopi bagi penderita jantung koroner.

Hubungan Kadar Kolesterol Total Dan Hipertensi Dengan Kejadian Penyakit Jantung Koroner DI RSUD dr. Soedarso Pontianak

2018 ◽  
Vol 1 (2) ◽  
pp. 99
Author(s):  
Laila Kamila ◽  
Maulidiyah Salim
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Total Cholesterol ◽  
Blood Vessels ◽  
Public Hospital ◽  
Sampling Technique ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Purposive Sampling

Abstract: Coronary heart is a disease that offense to blood vessels and heart attack due to constriction of blood vessels. A high level of cholesterol in blood or exceeds the normal limit can form sediment in wall of blodd vessels which cause blood vessels constriction or blockage. This research object to determine whether there is a correlation between cholesterol level total and hypertension with coronary heart disease in patients who hospitalized in Regional Public Hospital of dr. Soedarso Pontianak. This study was used cross sectional design, purposive sampling technique, it gained 50 people as samples. The measurement of blood pressure was done in heart poly and cholesterol total level in clinic laboratory of Regional Public Hospital of dr. Soedarso by using enzymatic CHOD-PAP method. It can be obtained that 10 people had hypertension and 40 people did not.the average of total cholesterol was 224 mg/dl. Maximum value of total cholesterol was 224 mg/dl and 152 mg/dl as minimum value. Data has been analyzed by using statistical test, Chi-Square, to determine the correlation of total cholesterol wit coronary heart disease, obtained p value=0,024 (less than α=0,05). Correlation of hypertension and coronary heart disease gained p value=0,923 (more than α=0,05), it can be concluded that total cholesterol correlated with coronary heart disease, and there was not a correlation between hypertension and coronary heart disease.Abstrak: Jantung koroner adalah penyakit yang  menyerang pembuluh darah dan serangan jantung, karena penyempitan pada pembuluh darah. Kadar kolesterol yang tinggi dalam darah melebihi normal dapat membentuk endapan pada dinding pembuluh darah sehingga menyebabkan penyempitan dan tersumbatnya pembuluh darah. Penelitian ini bertujuan untuk mengetahui hubungan kadar kolesterol total dan hipertensi dengan penyakit jantung koroner pada pasien di RSUD dr. Soedarso Pontianak. Disain penelitian  ini menggunakan cross sectional, teknik pengambilan sampel yaitu purposive sampling, didapat jumlah sampel 50 orang. Pengukuran Tensi Darah dilakukan di poli Jantung dan pemeriksaan kadar kolesterol total di laboratorium klinik RSUD dr. Soedarso Pontianak dengan metode enzimatik CHOD-PAP. Hasil penelitian didapatkan 10 orang mengalami hipertensi dan 40 orang non hipertensi. Rata-rata kadar kolesterol total 224 mg/ dl. Nilai maksimum kadar kolesterol total yaitu 224 mg/dl dan nilai minimum yaitu 152 mg/dl. Analisa data dengan uji statistik Chi-square untuk mengetahui hubungan kolesterol total dengan penyakit jantung koroner didapatkan nilai p = 0,024 (lebih kecil dari  α 0,05). Uji hubungan hipertensi dengan penyakit jantung koroner didapat nilai p = 0,923 (lebih besar dari α 0,05), dapat disimpulkan terdapat hubungan kadar kolesterol total dengan penyakit jantung koroner dan tidak ada hubungan hipertensi dengan penyakit jantung koroner.

Treatment with Simvastatin and Low-dose Aspirin Depresses Thrombin Generation in Patients with Coronary Heart Disease and Borderline-high Cholesterol Levels

2001 ◽  
Vol 85 (02) ◽  
pp. 221-225 ◽  
Author(s):  
Anetta Undas ◽  
Robert Undas ◽  
Jan Brożek ◽  
Andrzej Szczeklik ◽  
Jacek Musiał
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Thrombin Generation ◽  
Low Dose ◽  
Ex Vivo ◽  
Blood Cholesterol ◽  
High Cholesterol ◽  
Cholesterol Levels ◽  
Dose Aspirin ◽  
Low Dose Aspirin

SummaryAspirin and statins are beneficial in coronary heart disease across a broad range of cholesterol levels. We assessed the effects of low-dose aspirin (75 mg daily) on thrombin generation in patients with coronary heart disease and average blood cholesterol levels. We also investigated whether in patients with borderline-high cholesterol level who have been already taking aspirin, additional treatment with simvastatin would affect thrombin generation.Seven-day treatment with low-dose aspirin decreased thrombin generation ex vivo only in patients with total cholesterol 5.2 mmol/L. In patients with higher cholesterol levels aspirin had no effect. In these patients, already taking low-dose aspirin, additional three-month simvastatin treatment resulted in a reduction of thrombin generation. This demonstrates that low-dose aspirin depresses thrombin generation only in subjects with desirable blood cholesterol levels, while in others, with borderline-high cholesterol, thrombin formation is being reduced following the addition of simvastatin.

Serum total cholesterol levels and risk of mortality from stroke and coronary heart disease in Japanese: The JACC study

2007 ◽  
Vol 194 (2) ◽  
pp. 415-420 ◽  
Author(s):  
Renzhe Cui ◽  
Hiroyasu Iso ◽  
Hideaki Toyoshima ◽  
Chigusa Date ◽  
Akio Yamamoto ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Total Cholesterol ◽  
Serum Total Cholesterol ◽  
Cholesterol Levels ◽  
Risk Of Mortality

scholarly journals Pengaruh Asam Lemak Jenuh, Tidak Jenuh dan Asam Lemak Trans terhadap Kesehatan

2008 ◽  
Vol 2 (4) ◽  
pp. 154 ◽  
Author(s):  
Ratu Ayu Dewi Sartika
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Fatty Acid ◽  
Total Cholesterol ◽  
Saturated Fatty Acid ◽  
Trans Fatty Acid ◽  
Blood Cholesterol ◽  
Degenerative Diseases ◽  
High Blood Cholesterol ◽  
Fatty Acid Trans

Dewasa ini pola makan modern sering dihubungkan dengan meningkatnya kadar kolesterol di dalam darah. Tingginya kolesterol darah dapat memicu munculnya penyakit degeneratif seperti stroke dan penyakit jantung koroner. Jenis makanan yang diduga berpengaruh terhadap timbulnya penyakit degeneratif yaitu makanan yang mengandung asam lemak jenuh dan asam lemak trans. Asam lemak trans memiliki pengaruh hampir 2 kali lipat dalam meningkatkan rasio K-LDL/K-HDL dibandingkan dengan asam lemak jenuh. Perubahan pada rasio kolesterol total/HDL-K atau K-LDL/K-HDL merupakan prediktor CHD (Coronary Heart Disease).Kata kunci : Asam lemak jenuh, asam lemak trans, penyakit degenatifAbstractNowadays modern meal pattern is related to the increase of cholesterol level in the blood. The high blood cholesterol can lead to degenerative diseases such as stroke and coronary heart disease. Foods that suspected to influence the occurrence of degenerative diseases are saturated fatty acid and trans fatty acid. Trans fatty acid can influence almost twice higher in increasing ratio of K-LDL/K-HDL compared to saturated fatty acid. The change in ratio of total cholesterol/ HDL-K or K-LDL/K-HDL is predictor of coronary heart disease.Keywords : Saturated fatty acid, trans fatty acid, degenerative diseases

scholarly journals Hubungan periodontitis dengan penyakit jantung koroner pada pasien di RSUP Prof. Dr. R. D. Kandou Manado

e-GIGI ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Jolanda P. Ticoalu ◽  
Billy J. Kepel ◽  
Christy N. Mintjelungan
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Periodontal Disease ◽  
Systemic Disease ◽  
Case Control ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Cross Sectional Design

Abstract: Periodontitis is one of the factors causing systemic disease. It is often associated with increasing signs of inflammation and it is also an indicator of the risk factors of coronary heart disease (CHD). Infection of periodontal structures can accelerate the form of atherosclerosis that causes coronary heart disease due to systemic inflammation through the release of endotoxins, proteins, or acute phase reactors. This was a case control analytical study with a cross sectional design conducted at Prof. Dr. R. D. Kandou Hospital Manado from August to September 2016. There were 40 respondents (20 CHD patients and 20 non-CHD patients) obtained by using total sampling method. Periodontal disease indexes of the samples were evaluated by using periodontal disease index of Ramfjord 1959. The Chi-square test showed a p value of 0.01. Conclusion: There was a significant relationship between periodontitis and coronary heart disease in patients at Prof. Dr. R. D. Kandou Hospital Manado. Keywords: periodontitis, Coronary Heart Disease (CHD) Abstrak: Periodontitis merupakan salah satu faktor penyebab penyakit sistemik. Pada periodontitis sering didapatkan peningkatan tanda-tanda inflamasi yang juga merupakan salah satu indikator dari faktor risiko penyakit jantung koroner (PJK). Infeksi struktur periodontal dapat mempercepat pembentukan aterosklerosis yang menjadi penyebab PJK dengan cara menimbulkan inflamasi sistemik melalui pelepasan endotoksin, protein, atau reaktor fase akut. Jenis penelitian ialah analitik menggunakan case control dengan desain potong lintang. Penelitian dilakukan di RSUP Prof. Dr. R. D. Kandou Manado pada bulan Agustus sampai September 2016. Terdapat 40 responden (20 pasien PJK dan 20 pasien non PJK) diperoleh dengan menggunakan metode total sampling. Pada penelitian ini dilakukan pengukuran indeks penyakit periodontal menggunakan pengukuran PDI Ramfjord 1959. Analisis data menggunakan uji Chi-square. Hasil analisis bivariat menggunakan uji Chi-square menunjukkan nilai p=0,01 (0,01<0,05) yang menyatakan bahwa terdapat hubungan antara periodontitis dengan PJK pada pasien di RSUP Prof. Dr. R. D. Kandou Manado. Simpulan: Terdapat hubungan bermakna antara periodontitis dengan penyakit jantung koroner pada pasien di RSUP Prof. Dr. R. D. Kandou Manado.Kata kunci: periodontitis, penyakit jantung koroner (PJK)

scholarly journals Cholesterol Screening in Children and Family History of Coronary Heart Disease.

Circulation ◽  
2001 ◽  
Vol 103 (suppl_1) ◽  
pp. 1369-1369
Author(s):  
Viktorina N Muratova ◽  
Syed S Islam ◽  
Emily C Spangler ◽  
Ellen W Demerath ◽  
William A Neal
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Family History ◽  
Lipid Profile ◽  
School Children ◽  
Preventive Health Care ◽  
Blood Cholesterol ◽  
Cholesterol Screening ◽  
Cholesterol Levels ◽  
History Of

P94 Background: Selective blood cholesterol screening of children based upon National Cholesterol Education Program (NCEP) guidelines of family history of premature cardiovascular disease (CVD) or parental hypercholesterolemia is inadequate in a population with high prevalence of coronary heart disease (CHD), low levels of cholesterol screening, low socio-economic status (SES) and diminished access to preventive health care. We hypothesize that universal cholesterol screening of pre-pubertal school children may be effective in identifying children and their parents with abnormal lipid levels in this high risk rural population. Fifth grade school children from seven rural Appalachian counties participated in a school based cholesterol screening program. Data on family history of premature CHD, anthropometric and blood pressure measurements, tobacco smoke exposure, dietary history and physical activity levels were collected at the time of screening. Seven hundred and nine 5 th grade students ( mean age 10.8 years) participated in the program. One hundred seventy four (24.5%) were considered presumptively dyslipidemic after non-fasting finger- stick (FS) cholesterol screening. Thirty six percent of these dyslipidemic children had a fasting lipid profile done. Dyslipidemia was confirmed in 37(59%) of these children. FS cholesterol levels were significantly correlated with fasting TC (r=0.80 p < 0.0001). Among confirmed dyslipidemic children, family history was not a good predictor of dyslipidemia (sensitivity 21.6%). Seventy nine parents of dyslipidemic children participated in fasting lipid profile assessment. Fifty two parents (67%) were dyslipidemic, most of them (79%) did not have a family history of premature CHD or hypercholesterolemia. FS cholesterol levels were also correlated with fasting TC of fathers (r=0.46 p=0.01), and mothers (r=0.32 p=0.02). Conclusion: Significant correlation exists between non-fasting FS cholesterol levels of children and subsequent fasting lipid profile of children and their parents. Family history has low sensitivity in predicting children with elevated serum cholesterol concentrations.

CHILDHOOD DIET AND CORONARY HEART DISEASE

PEDIATRICS ◽  
1972 ◽  
Vol 49 (2) ◽  
pp. 305-307
Author(s):  
L. J. Filler ◽  
Lewis A. Barness ◽  
Richard B. Goldbloom ◽  
James C. Haworth ◽  
Malcolm A. Holliday ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Dietary Intervention ◽  
Dietary Habits ◽  
Dietary Cholesterol ◽  
Later Life ◽  
Blood Cholesterol ◽  
Cholesterol Levels ◽  
Childhood Diet ◽  
Special Circumstances

A subcommittee of the Inter-Society Commission for Heart Disease Resources recently recommended an immediate, nationwide change in dietary habits to reduce the risk of coronary heart disease in later life.1 Specifically, the Commission urges that people eat less than 300 mg of cholesterol each day, that the total calories from fat be less than 35% of the diet, and that the fat calories essentially be divided equally among saturated, monounsaturated, and polyunsaturated sources. (A commentary on these recommendations appears in this issue of Pediatrics.2) The Committee on Nutrition, realizing that pediatricians will increasingly be asked about diets for children to reduce the risk of heart disease in later life, has evaluated the Commission's report for its application to pediatric practice. The Committee stresses that such dietary intervention is, at present, experimental and recommends against dietary changes for all children. Dietary intervention may be warranted in special circumstances, but not before 1 year of age. Reasons for these recommendations will be given in this report. The evidence relating dietary cholesterol to coronary heart disease is summarized as follows: 1. Some inborn or acquired diseases with hypercholesterolemia are associated with premature atherosclerosis. 2. Serum cholesterol levels are higher than usual in persons with coronary heart disease. 3. Persons with high cholesterol levels in prospective studies developed coronary heart disease more often than those with normal levels. 4. The mortality rate from coronary heart disease in different countries varies in relation to the average blood cholesterol values (or dietary fat intake). 5. Experimentally induced hypercholesterolemia in animals is associated with atherosclerotic deposits.

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