Citric Acid Monohydrate

Nanoscale ZnO powders were synthesized via the combustion method using zinc nitrate hexahydrate as the source (oxidant) material and urea, and glycine or citric acid monohydrate as fuels.

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Prevention of Cap-Locking of Syrup Product by Treating the Manufacturing Process of Sugar Syrup with Citric Acid Monohydrate

Bangladesh Pharmaceutical Journal ◽

10.3329/bpj.v19i2.29279 ◽

2016 ◽

Vol 19 (2) ◽

pp. 190-196

Author(s):

Mia Mohammad Dulal ◽

Md Kaisarul Islam ◽

Abu Asad Chowdhury ◽

Jakir Ahmed Chowdhury

Keyword(s):

Citric Acid ◽

Manufacturing Process ◽

Room Temperature ◽

Pharmaceutical Journal ◽

Invert Sugar ◽

Citric Acid Monohydrate ◽

Sugar Syrup ◽

Bottle Neck ◽

Zero Time

The aim of the study was to prevent crystallization of sucrose on the bottle neck and cap of sugar syrup containing products by treating the manufacturing process with citric acid monohydrate. Diphenhydramine HCl syrup was selected as a model product for the experiment. Sugar syrup (66% w/w sucrose) and partially inverted sugar syrup (in which 66% w/w sucrose was treated with citric acid monohydrate for partially conversion of sucrose into invert sugars) were prepared and the content of invert sugar of both the sugar syrups were determined. Sugar syrup and citric acid monohydrate treated sugar syrup (partially inverted) were considered as control and test sugar syrup, respectively which were used to manufacture the Diphenhydramine HCl syrup product. The Diphenhydramine HCl syrup product that prepared using sugar syrup was considered as control syrup product and that was prepared using citric acid monohydrate treated sugar syrup (partially inverted) was considered as the test syrup product. Then experiments were designed in such a way that both control (sugar syrup and product prepared by it) and test samples (partially inverted syrup and product prepared by it) were spread on open petridishes and also spread on the neck of filled bottle, inside of caps and the bottles, which were kept at room temperature (25 0C) for 2 weeks observation. At zero time and after two weeks, crystal growths of sucrose for each experiment were checked visually. No crystal was observed in open petridishes and bottle necks of partially inverted sugar syrup of Diphenhydramine HCl syrup prepared by using partially inverted sugar syrup, where content of invert sugars was more than 75 % w/w, but remarkable crystal growths were found in open petridishes and bottle necks of sugar syrup and Diphenhydramine HCl syrup prepared by using sugar syrup, where the content of invert sugars was less than 15 % w/w.Bangladesh Pharmaceutical Journal 19(2): 190-196, 2016

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Effect of Treatment Conditions on Nisin Inactivation of Gram-negative Bacteria

Journal of Food Protection ◽

10.4315/0362-028x-55.10.763 ◽

1992 ◽

Vol 55 (10) ◽

pp. 763-766 ◽

Cited By ~ 101

Author(s):

KELLY A. STEVENS ◽

BRIAN W. SHELDON ◽

N. ARLENE KLAPES ◽

TODD R. KLAENHAMMER

Keyword(s):

Citric Acid ◽

Incubation Temperature ◽

Chelating Agent ◽

Gram Negative Bacteria ◽

Citric Acid Monohydrate ◽

Gram Negative ◽

Treatment Conditions ◽

Effect Of Treatment ◽

Gram Negative Organisms ◽

Sodium Phosphate Dibasic

A method using nisin and a chelating agent to inactivate Salmonella species and other gram-negative bacteria has been developed. The objective of this study was to determine the effect of treatment conditions on the application of this method. Ten gram-negative organisms were used in this study, including six Salmonella species commonly associated with foodborne illness. Organisms were selected on the basis of sensitivity to nisin and a chelating agent. The following parameters were examined: (a) chelating agent, (b) nisin concentration, (c) incubation temperature, and (d) protein interference. Chelating agents included EDTA, ethylenebis (oxyethylene-nitrilo) tetraacetic acid, citric acid monohydrate, and sodium phosphate dibasic. The most effective treatment consisted of 50 to 100 μg/ml nisin applied in combination with 20 mM EDTA or citric acid monohydrate at a temperature range of 30 to 42°C. All of the chelators examined exhibited some inhibitory activity. The addition of bovine serum albumin to the treatments containing nisin and EDTA did not result in a significant decrease in inhibitory action.

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