Non invasive assessment of the internal carotid artery in stroke patients

1983 ◽  
Vol 43 (4) ◽  
pp. 275-283 ◽  
Author(s):  
M. von Arbin ◽  
M. Britton ◽  
U. De Faire ◽  
P. Gustafsson
Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Ethem M Arsava ◽  
Dogan Dinc Oge ◽  
Ozge Berna Gultekin-Zaim ◽  
Ekim Gumeler ◽  
Jeong-Min Kim ◽  
...  

Background: Intracranial internal carotid artery calcifications (IICAC), considered a phenomenon within the spectrum of atherosclerosis and vascular aging, are frequently encountered in ischemic stroke patients. While intimal IICAC directly contributes to ischemic stroke pathophysiology, the medial counterpart is generally deemed as a risk factor for vascular end-points. Apart from aging and cardiovascular risk factors, the underlying pathophysiology that contributes to development of IICAC is not well understood; herein we studied the interplay between mineral and skeletal metabolism biomarkers, and IICAC presence and pattern. Methods: In a prospective series of 194 ischemic stroke patients (mean±SD age: 69±14 yr), blood samples were collected to determine calcium, phosphorus, magnesium, osteocalcin, parathyroid hormone, and vitamin D levels within 72 hours of symptom onset. IICAC presence and type was determined on admission CT-angiography source images; a medial or intimal type of IICAC category was assigned according to Kockelkoren criteria. Results: A total of 45 (23%) patients had no calcifications, while 95 (49%) had an intimal pattern and 54 (28%) had non-intimal (or medial) pattern. Apart from the well-known factors related with IICAC, such as age, lower glomerular filtration rate (GFR), history of hypertension, diabetes mellitus, coronary artery disease and atrial fibrillation, we identified admission magnesium levels to be associated with IICAC presence and pattern (no calcification: 1.96±0.18 mEq/L, intimal calcification 1.93±0.19 mEq/L, medial calcification: 1.81±0.28 mEq/L; p=0.006). None of the other biomarkers had any significant relationship to IICAC. In multivariate models, a lower magnesium level was significantly associated with medial calcification (each 0.1 mEq/L drop increased the odds by 1.2 (95% CI 1.0-1.4; p=0.046)), in addition to older age, history of diabetes mellitus and lower GFR. Conclusion: Hypomagnesemia is one of the factors well-known to be associated with vascular calcifications in the body. Our findings, extend this relationship to the intracranial vascular bed. No similar association was observed for other biomarkers related to mineral and skeletal metabolism. (Funding: TUBITAK grant 218S753)


2017 ◽  
Vol 28 (3) ◽  
pp. 339-344 ◽  
Author(s):  
Jan W. Dankbaar ◽  
◽  
Kelly G. P. Kerckhoffs ◽  
Alexander D. Horsch ◽  
Irene C. van der Schaaf ◽  
...  

1992 ◽  
Vol 55 (2) ◽  
pp. 98-104 ◽  
Author(s):  
W Mullges ◽  
E B Ringelstein ◽  
M Leibold

2017 ◽  
Vol 12 (1) ◽  
pp. 1384290 ◽  
Author(s):  
Yasin Hamarat ◽  
Mantas Deimantavicius ◽  
Evaldas Kalvaitis ◽  
Lina Siaudvytyte ◽  
Ingrida Januleviciene ◽  
...  

2017 ◽  
Vol 10 (7) ◽  
pp. 653-656 ◽  
Author(s):  
Marcelo Rocha ◽  
William T Delfyett ◽  
Vikas Agarwal ◽  
Amin Aghaebrahim ◽  
Ashutosh Jadhav ◽  
...  

BackgroundExtracranial internal carotid artery (ICA) occlusion can be overestimated on emergent single phase CT angiography (CTA) of stroke patients with isolated intracranial ICA occlusion. We aimed to measure the ability of identifying the extracranial site of presumed tandem ICA occlusions on pre-procedural CTA relative to catheter angiography during acute endovascular stroke therapy.MethodsRetrospective study of patients with intracranial ICA occlusion, with or without extracranial ICA occlusion, who underwent single phase CTA before acute endovascular treatment. Two neuroradiologists reviewed CTA images for the presence or absence of extracranial ICA occlusion, blinded to the catheter angiography results. The sensitivity, specificity, and predictive values of presumed extracranial ICA occlusions on CTA were calculated in reference to catheter angiography.Results91 stroke patients with acute intracranial ICA occlusion met the inclusion criteria for the study. 24% of patients (22/91) had tandem ICA occlusion confirmed on catheter angiography. Single phase CTA had a sensitivity of 95.5% (95% CI 77.2 to 99.9%) and a specificity of 69.6% (95% CI 57.3 to 80.1%) for concomitant extracranial ICA occlusion (false positive rate 30.4%). The positive and negative predictive values of single phase CTA for extracranial ICA occlusion in the presence of a distal ICA occlusion were 50% (95% CI 34.2 to 65.8%) and 98% (95% CI 89.1 to 100%), respectively.ConclusionsEmergency single phase CTA is highly sensitive but has reduced specificity to identify extracranial ICA occlusion in patients with intracranial ICA occlusion, which may confound planning for acute endovascular stroke therapy and cause over exclusion of patients with isolated ICA terminus occlusion from clinical trials.


2020 ◽  
Vol 412 ◽  
pp. 116760
Author(s):  
Tatsuo Mano ◽  
Takahiro Nakayama ◽  
Hironobu Endo ◽  
Keiko Bono ◽  
Ichiro Imafuku

1998 ◽  
Vol 112 (2) ◽  
pp. 196-198 ◽  
Author(s):  
S. C. Coley ◽  
A. Clifton ◽  
J. Britton

AbstractWe report the case of a giant fusiform aneurysm of the petrous internal carotid artery in a 15-year-old patient who had presented with headache, hearing loss and Horner's syndrome. Definitive radiological diagnosis was made by non-invasive imaging techniques, including magnetic resonance angiography (MRA). The aneurysm was obliterated by endovascular balloon occlusion following successful tolerance of test occlusion of the internal carotid artery.


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