Evaluation of Propess outcomes for cervical ripening and induction of labour in full-term pregnancy

Post term pregnancy is used to describe pregnancy that continues for 294 days ormore following the first day of last menstrual period. Post term pregnancy has been consideredto occur in 10-20 % of all pregnancies. PGE2 have been used vaginally for induction of labourfor the last two decades. Routine induction of labour after 41 weeks gestation appears to reduceperinatal mortality. Objectives: The study was done to: 1) To calculate the induction – deliverytime with prostaglandins E2 in prolonged pregnancy. 2) To find frequency of normal vaginaldelivery versus caesarean section after induction with prostaglandins E2. Study design: It wasdescriptive study. Setting: It was study of fifty patients carried out in Gynae unit 1 Allied HospitalFaisalabad. Period: 03 March 2005 to 02 March 2006. Subjects: Inclusion Criteria: 1) Allpatients with prolonged pregnancy of more than forty two weeks were included. 2-Only singletonpregnancies were included. Exclusion criteria: 1-Patients who had previous caesarean sectionwere excluded from the study. 2) Patients who had associated obstetric condition that modify themode of delivery were excluded. Data collection procedure: Detailed history and examinationwas carried out with availability of dating ultrasound to ascertain dates. Bishop score assessed.Tests of foetal well being carried out. After informed consent induction of labour carried out withprostin E2, and effect studied on induction – onset and delivery intervals and mode of delivery.Results: Induction onset interval was 3.5 hours in Primigravida, was 2.8 hours in group 2(G2 &G3) and 2.0 hours in group 3(G4 & more). Induction delivery interval was 18 hours in group 1,14 hours in group 2 and 10-12 hours in group 3. Mean percentage of normal vaginal deliverywas 78.5% in all groups. Forceps delivery was 5.6% and caesarean section was 15.7%. Numberof patients successfully induced was 84.2% Conclusion: The study confirmed the efficacy ofPGE2 tablets in achieving cervical ripening. It was also seen to decrease induction deliveryinterval more so in multigravida.

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TO COMPARE THE EFFICACY OF PGE2 GEL AND 25ΜG OF INTRAVAGINAL MISOPROSTOL FOR INDUCTION OF LABOR IN TERM PROM

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i1.838 ◽

2020 ◽

Vol 4 (1) ◽

Author(s):

Sunita Maheshwari ◽

Shweta Jinger

Keyword(s):

Low Dose ◽

Induction Of Labour ◽

Cervical Ripening ◽

Labour Induction ◽

Term Pregnancy ◽

Vaginal Tablet ◽

Misoprostol Group ◽

Group A ◽

Vaginal Misoprostol ◽

Group B

Background: Induction of labour is one of the most common obstetric interventions worldwide. The study was conducted to compare the efficacy and safety of 25µg (low dose) vaginal Misoprostol with intracervical Dinoprostone for cervical ripening and induction of labour in term pregnancy. Methods: For the purpose of this study, 100 term pregnancy patients (only primigravidae and second gravidae) were included who had spontaneous rupture of membrane before onset of labor. Data was collected from cases admitted in labor room at Pannadhay Mahila Chikitsalaya associated with RNT Medical College,Udaipur between July 2014 to July 2015. Results: Requirement of Oxytocin for augmentation of labor between group A and group B. It is evident from the table that oxytocin was required in only 16% of patients in group A, while 46% in group B. This indicates that requirement of oxytocin was significantly less in misoprostol group (P<0.001). Conclusion: This study was designed to assess efficacy of a 25 μg misoprostol vaginal tablet, Finding confirms that vaginal misoprostol tablet is as effective as dinoprostone in cervical ripening and labour induction with dinoprostone. Keywords: Cervical ripening, Dinoprostone, Labour induction, Low- dose misoprostol.

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Application of COOK ok Cervical Ripening Balloon Combined With Artificial Rupture of Membranes and Oxytocin in Labor Induction for Full-term Pregnancy

10.21203/rs.3.rs-96849/v1 ◽

2020 ◽

Author(s):

Ying Dong ◽

Chuyu Li ◽

Xin Zhao ◽

Lin Zhang ◽

Xiaojun Jia ◽

...

Keyword(s):

Adverse Events ◽

Pregnant Women ◽

Infant Health ◽

Mode Of Delivery ◽

Balloon Dilation ◽

Labor Induction ◽

Induction Of Labor ◽

Full Term ◽

Cervical Ripening ◽

Term Pregnancy

Abstract Background The use of COOK balloon in the process of induction of labor is gradually promoted. This study was conducted to investigate the safety and efficacy of COOK double balloon dilation for pre-induction cervical maturation and induction of labor. Methods A total of 343 pregnant women with full-term pregnancy in Shanghai Putuo Maternity & Infant Health Hospital from January 1st to September 30th of 2016 were enrolled. Of all the pregnant women, 166 had labor induction, which included the use of a COOK balloon, the implementation of artificial rupture of membranes (AROM) and oxytocin intravenous (IV) drip (COOK group). The other 177 pregnant women with spontaneous rupture of membranes (SROM) and mature cervix only administrated with oxytocin IV drip to promote regular uterus contraction (oxytocin group). Maternal adverse reactions, mode of delivery and delivery outcomes of two groups were subsequently compared between the two groups. Results There were significant differences of maternal age (28.29 ± 3.34 vs. 29.25 ± 3.62 years, P = 0.02), gestational age (283.49 ± 4.53 vs. 274.71 ± 7.04 years, P < 0.001) and birth weight (3435.27 ± 340.29 vs. 3354.63 ± 387.96 g, P = 0.02) between the COOK group and the oxytocin group. There were no significant differences in terms of gravidity, parity, mode of delivery, analgesia, 1 min and 5 min Apgar score, labor time, postpartum hemorrhage, and adverse events. Conclusion Use of a COOK balloon may help full-term pregnancy women with immature cervix obtain the same pregnancy results as those with mature cervix, without extra occurrence of adverse events.Trial registration This is an observational study and no registration is required.

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COMPARISON OF SAFETY AND EFFICACY OF INTRACERVICAL DINOPROSTONE GEL AND EXTRA-AMNIOTIC FOLEY'S CATHETER FOR INDUCTION OF LABOUR

10.36106/2308074 ◽

2021 ◽

pp. 13-15

Author(s):

Radha Garg ◽

Bharti Saxena ◽

Neha Dhingra ◽

Madhu Meena

Keyword(s):

Mode Of Delivery ◽

Full Term ◽

Induction Of Labour ◽

Cervical Ripening ◽

Labour Induction ◽

Vaginal Deliveries ◽

Before And After ◽

The Difference ◽

Foley’S Catheter ◽

Group B

BACKGROUND: The uterus remains quiescent throughout 9 months and begins to act on its own when full term is approached. Almost 50% women deliver in the duration of one week before and after the calculated EDD; and induction of labour is needed in about 20% of women: to increase the success of labour induction, to reduce the duration and complications of labour and to diminish the rate of caesarean sections. Cervical ripening is needed before induction of labour. There are many methods for induction of labour; however till date, none of them can claimed to be the best. To compare the AIM OF PRESENT STUDY: safety and efcacy of Dinoprostone gel versus intracervical foley's catheter for ripening of cervix and induction of labour. Compara MATERIAL AND METHODS: tive prospective study was conducted on 400 full term uncomplicated primigravida women needing induction of labour between January 2019 to June 2020 in department of obstetrics & gynecology at GMC Kota in Rajasthan.Group A: 200 women induced with Dinoprostone gel and Group B: 200 women induced with extra-amniotic Foley's catheter. Baseline characteristics like maternal age, gestational age, indication for induction were comparable in both the groups. The mean induction to delivery interval was shorter in RESULT: group A (12.69 ± 3.64 hours) as compared to Group B (18.17 ± 3.17 hours) and this difference was statistically highly signicant (P = 0.0001). There was no signicant difference observed in mode of delivery, labour progress at 18 hours, indication for caesarean section, maternal side effects, mean birth weight, Apgar score at 5 mins, number of NICU admissions between the two groups. The number of vaginal deliveries we CONCLUSION: re similar in both the groups but mean induction to delivery interval was signicantly shorter with Dinoprostone gel. However, the maternal and fetal outcomes were better in Foley's catheter group although the difference was not statistically signicant

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Maternal and neonatal outcome after the use of low dose sublingual 25 µg misoprostol for labour induction in women with term pregnancy

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20213843 ◽

2021 ◽

Vol 10 (10) ◽

pp. 3817

Author(s):

Sumitra Gajraj ◽

Anupam Kapur

Keyword(s):

Low Dose ◽

Neonatal Outcome ◽

Induction Of Labour ◽

Cervical Ripening ◽

Labour Induction ◽

Care Hospital ◽

Term Pregnancy ◽

Total Study Population ◽

Qualitative Variables ◽

Study Population

Background: Aim of this study was to assess the maternal and fetal/neonatal outcome after the use of low dose (25 µg) misoprostol for labour induction in women with term pregnancy (gestational age >37 weeks POG) with a live foetus.Methods: The prospective interventional study was designed at the department of obstetrics and gynaecology of a tertiary health care hospital, with a sample size of 150 pregnant ladies who had to undergo induction of labour, were selected depending on the defined inclusion and exclusion criteria. Data was analysed using SPSS 18. Descriptive statistics were used to describe the data. Qualitative variables were presented as frequencies and percentage.Results: About 41% (61 patients) of the total study population was in the age group of 26 to 30 years with only two patients aged >35 years of age. The study group comprised of 88 primigravida (59%) and 62 multigravida (41%). The most common indication for induction of labour in my study was post-dated pregnancy (47%) followed by PROM (22%).Conclusions: The use of low dose (25 µg) misoprostol sublingually is definitely very effective in cervical ripening and induction of labour in term pregnancies particularly in those with poor Bishops score. There was no significant neonatal or maternal morbidity associated with induction of labour with low dose sublingual misoprotol.

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