Body composition and weight gain in new users of the three-monthly injectable contraceptive, depot-medroxyprogesterone acetate, after 12 months of follow-up

Kontrasepsi suntik merupakan salah satu kontrasepsi hormonal yang masih menjadi pilihan akseptor dalam mengatur kehamilan. Namun demikian, penggunaan kontrasepsi suntik Depot Medroxyprogesterone Acetate (DMPA) diketahui dapat meningkatkan berat badan selama pemakaian enam (6) bulan atau lebih. Tujuan penelitian ini dilakukan untuk menganalisis pengaruh penggunaan DMPA terhadap kenaikan berat badan akseptor. Penelitian ini merupakan penelitian observasional dengan rancangan penelitian potong lintang (cross sectional) yang bersifat analitik. Populasi dalam penelitian ini adalah seluruh akseptor baru suntik DMPA di Puskesmas Perumnas II Pontianak pada bulan Januari 2018 hingga Maret 2019. Variabel dari penelitian ialah usia, pekerjaan, paritas, dan kenaikan berat badan. Analisis dilakukan dengan menggunakan analisis paired t-test. Teknik pengambilan sampel yang digunakan ialah purposive sampling. Jumlah sampel yang memenuhi kriteria inklusi dan ekslusi sebanyak 81 akseptor. Dari hasil penelitian ini diperoleh bahwa sebagian besar akseptor berusia 20-35 tahun (71,6%), bekerja sebagai ibu rumah tangga (97,5%), mempunyai 2 anak atau lebih (77,8%), dan memiliki kenaikan berat badan 0-2 kg (44,4%). Berdasarkan hasil analisis paired t-test bahwa penggunaan suntik KB 3 bulan (DMPA) memiliki pengaruh terhadap kenaikan berat badan akseptor dengan nilai p=0,001. Kesimpulan dari penelitian ini bahwa terdapat pengaruh penggunaan DMPA terhadap kenaikan berat badan akseptor. Injectable contraception is a hormonal contraceptive used by acceptors in regulating pregnancy. However, the use of Depot Medroxyprogesterone Acetate (DMPA) is known to increase body weight after six months of use or more.. The purpose of this study was to analysis the effect of using DMPA on weight gain. This study was an observational study with cross sectional analytic study design. The population in this study were all new acceptors who used DMPA at the Perumnas II Pontianak Public Health Care in January 2018 to March 2019. Variables from the study were age, occupation, parity, and weight gain. Analysis was performed using paired t-test analysis. The sampling technique used was purposive sampling, where the number samples that met the inclusion and exclusion criteria were 81 acceptors. The results showed that most of the acceptors were aged 20-35 years (71,6%), work as housewives (97,5%), had 2 or more children (77,8%), and gained weight 0-2 kg (44,4%). Based on the results of paired t-test analysis, the use of DMPA has an effect on the acceptor’s weight gain with a value of p = 0.001. The conclusion of this study is that there is an effect of the use of DMPA on acceptor weight gain.Keywords: Acceptors, DMPA, weigt gain

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Changes in weight and body composition after initiating insulin therapy and their relationship with metabolic control during the first year of type 1 diabetes in adults. InLipoDiab1 Study

Journal of Medical Science ◽

10.20883/medical.e531 ◽

2021 ◽

pp. e531

Author(s):

Maja Miętkiewska ◽

Aleksandra Uruska

Keyword(s):

Body Composition ◽

Body Weight ◽

Weight Gain ◽

Insulin Therapy ◽

The Body ◽

First Year ◽

Newly Diagnosed ◽

Metabolic Management

Introduction. As in the general population, an increase in the incidence of overweight has been observed in individuals with type 1 diabetes (T1DM). Nevertheless, weight gain in this group may contribute to the deterioration of the metabolic management. The aim of this study was to evaluate changes in the body weight and body composition after initiating insulin therapy and to assess their relationship with the metabolic management during the first year of T1DM in adults.Material and Methods. The prospective analysis included 139 adults patients with newly diagnosed T1DM, treated with Intensive functional insulin therapy (IFI) from the onset of the disease (age 26.3 ± 5.9 years). Patients were assessed at the time of the diagnosis and after 12 months. Metabolic parameters, including the HbA1c and lipid profile were investigated. The group was divided according to weight gain during the follow-up period.Results. Weight gain was observed in 68.3% of participants (n = 95). In most cases an increase in body fat was found (41% vs 59% p = 0.01). Changes in the body weight corresponded to significant changes in body composition. Conversely, HbA1c decreased during the follow-up in all groups. The highest reduction was observed in a group with “excessive weight gain”. Additionally, a significant increase in high density lipoproteins was observed in each group. However, weight gain was not accompanied by a deterioration of the lipid profile.Conclusions. Weight gain is a considerable problem among adults with newly diagnosed T1DM and is connected mainly with an increase of adipose tissue above the normal range. Changes in the body weight, associated with body composition changes, did not result in the dysfunctions of the metabolic management.

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