scholarly journals Japanese Encephalitis Vaccination in Children Population of Nepal During the year 2005, 2006 and 2008

2009 ◽  
Vol 29 (2) ◽  
pp. 85-91
Author(s):  
Durga Datt Joshi
Keyword(s):  
High Risk ◽  
Japanese Encephalitis ◽  
Vaccine Coverage ◽  
Vaccination Campaign ◽  
Education Programme ◽  
Mosquito Vector ◽  
District Health ◽  
High Coverage ◽  
Secondary Sources ◽  
Central Offices

Japanese Encephalitis (JE) is caused by a Flavivirus that, in a proportion of human cases, causes severe encephalitis leading to death or sometimes permanent disablement. It is a zoonotic disease, transferred from animals (commonly pigs or wild birds) by a mosquito vector to humans. In Southeast Asia it is thought to cause up to 50000 clinical cases and 10000 deaths per year. JE vaccination programme was carried out in high risk districts of Nepal. Japanese encephalitis vaccination was carried out during the years 2005, 2006, 2008 and 2009. The data collected from primary and secondary sources from the District Health Offices and other concerned central offices of the Department of Health Services, was tabulated and analysed. Thirty-five lakh of JE vaccine doses was procured by the Ministry of Health during the year 2006/2007. This vaccine was used in children under 15 years of age of 12 districts of JE risk and high-risk areas of Nepal. It was found that during the year 2005; 85% children in Banke and 81% in Kailali were vaccinated against JE. In Kailali and Banke districts it was found to be about 103% coverage in children population targeted, in Dang district it was 100% coverage, and in Bardiya district it was 73% coverege but in Rupandehi and Kanchanpur districts it was only about 40% and 41% respectively. JE vaccine coverage was very low in two Rupandehi and Kanchanpur districts during 2005 and 2006 and very high coverage during the year 2008. JE vaccination coverage results for the year 2009 have not been made available yet due to unavailability of data. This type of mass vaccination campaign needs regularlity, mass awareness and health education programme should be carried out before JE vaccination campaign in the children in the future. Key words: Japanese Encephalitis, flavivirus, zoonotic, vector borne, lyophilized vaccine.   doi: 10.3126/jnps.v29i2.2045 J. Nepal Paediatr. Soc. Vol 29, No. 2, pp.85-91

scholarly journals Modeling the impact of COVID-19 vaccination in Lebanon: A call to speed-up vaccine roll out

2021 ◽  
Author(s):  
Ghina R Mumtaz ◽  
Fadi El-Jardali ◽  
Mathilda Jabbour ◽  
Aya Harb ◽  
Laith J Abu-Raddad ◽  
...  
Keyword(s):  
Vaccine Coverage ◽  
Vaccination Campaign ◽  
Scale Up ◽  
High Coverage ◽  
Social Distancing ◽  
Epidemic Curve ◽  
Limited Health ◽  
Care Capacity ◽  
The Impact ◽  
Roll Out

Background: Amidst a very difficult economic and political situation, and after a large first SARS-CoV-2 wave near the end of 2020, Lebanon launched its vaccination campaign on 14 February 2021. To date, only 6.7% of the population have received at least one dose of the vaccine, raising serious concerns over the speed of vaccine roll-out and its impact in the event of a future surge. Objective: Using mathematical modeling, we assessed the short-term impact (by end of 2021) of various vaccine roll-out scenarios on SARS-CoV-2 epidemic course in Lebanon. Results: At current immunity levels in the population, estimated by the model at 40% on 15 April 2021, a large epidemic wave is predicted if all social distancing restrictions are gradually eased and variants of concern are introduced. Reaching 80% vaccine coverage by end of 2021 will flatten the epidemic curve and will result in a 37% and 34% decrease in the peak daily numbers of severe/critical disease cases and deaths, respectively; while reaching intermediate coverage of 40% will result in only 10-11% decrease in each. Reaching 80% coverage by end of 2021 will avert 3 times more hospitalizations and deaths over the course of this year compared with 40% coverage. Impact of vaccination was substantially enhanced with rapid scale-up. Reaching 80% vaccine coverage by August would prevent twice as many severe/critical disease cases and deaths than if it were reached by December. Finally, a longer duration over which restrictions are eased resulted in a more favorable impact of vaccination. Conclusion: For vaccination to have an impact on the predicted epidemic course and associated disease burden in Lebanon, vaccination has to be rapid and reach high coverage (at least 70%), while sustaining social distancing measures during roll-out. At current vaccination pace, this is unlikely to be achieved. Concerted efforts need to be put to overcome local challenges and substantially scale up vaccination to avoid a surge that the country, with its multiple crises and limited health-care capacity, is largely unprepared for.

scholarly journals Modeling the Impact of COVID-19 Vaccination in Lebanon: A Call to Speed-Up Vaccine Roll Out

Vaccines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 697
Author(s):  
Ghina R. Mumtaz ◽  
Fadi El-Jardali ◽  
Mathilda Jabbour ◽  
Aya Harb ◽  
Laith J. Abu-Raddad ◽  
...  
Keyword(s):  
Vaccine Coverage ◽  
Vaccination Campaign ◽  
Scale Up ◽  
Short Term ◽  
High Coverage ◽  
Social Distancing ◽  
Epidemic Curve ◽  
Population Immunity ◽  
The Impact ◽  
Roll Out

Four months into the SARS-CoV-2 vaccination campaign, only 10.7% of the Lebanese population have received at least one dose, raising serious concerns over the speed of vaccine roll-out and its impact in the event of a future surge. Using mathematical modeling, we assessed the short-term impact of various vaccine roll-out scenarios on SARS-CoV-2 epidemic course in Lebanon. At current population immunity levels, estimated by the model at 40% on 15 April 2021, a large epidemic wave is predicted if all social distancing restrictions are gradually eased and variants of concern are introduced. Reaching 80% vaccine coverage by the end of 2021 will flatten the epidemic curve and will result in a 37% and 34% decrease in the peak daily numbers of severe/critical disease cases and deaths, respectively; while reaching intermediate coverage of 40% will result in only a 10–11% decrease in each. Reaching 80% vaccine coverage by August would prevent twice as many severe/critical disease cases and deaths than if it were reached by December. Easing restrictions over a longer duration resulted in more favorable vaccination impact. In conclusion, for vaccination to have impact in the short-term, scale-up has to be rapid and reach high coverage (at least 70%), while sustaining social distancing measures during roll-out. At current vaccination pace, this is unlikely to be achieved. Concerted efforts need to be made to overcome local challenges and substantially scale up vaccination to avoid a surge that the country, with its multiple crises and limited health-care capacity, is largely unprepared for.

scholarly journals Response of Various Stakeholders towards Newly Introduced Japanese Encephalitis Vaccine in a North Indian State

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Dinesh Kumar ◽  
Amar Jeet Singh
Keyword(s):  
Japanese Encephalitis ◽  
State Government ◽  
Vaccine Coverage ◽  
Vaccination Campaign ◽  
Immunization Schedule ◽  
State Health ◽  
Japanese Encephalitis Vaccine ◽  
National Immunization ◽  
Indian State ◽  
The Government

Introduction. Many attempts had been made to introduce newer vaccines into national immunization schedule of India. Special vaccines campaigns for diseases like JE were also initiated, which required a lot of preparation before vaccinating the beneficiaries. Objectives. To ascertain response of various stakeholders regarding launch of Japanese encephalitis vaccination campaign by state government in district Ambala, Haryana. Methodology. A 30-cluster survey was done to assess the vaccine coverage and views of the stakeholders. Various officials of state health services were also interviewed. Results. JE vaccine coverage was found to be 93.9%. Majority (59.8%) of the parents were informed about JE vaccination by the health worker. Many (83; 41.7%) parents said that they got their child vaccinated for JE since it “endangers life of children” and 82 (41.2%) said that “since everybody got it.” All the staff was trained for JE vaccination campaign. Conclusion. JE vaccination campaign was a success with adequate preparation. Majority of people accepted vaccine in good faith in the government rather than due to their knowledge about disease.

MEASLES OUTBREAK IN A RURAL AREA OF A DEVELOPING COUNTRY: A CASE CONTROL STUDY

2018 ◽  
Vol 7 (4) ◽  
pp. 197-201
Author(s):  
Mir M Hassan Bullo ◽  
Mirza Amir Baig ◽  
Jawad Faisal Malik ◽  
Ejaz Ahmad Khan ◽  
Muazam Abbas Ranjha ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vaccine Coverage ◽  
Significant Risk ◽  
Public Health Problem ◽  
Maculopapular Rash ◽  
Healthcare Facility ◽  
Control Measures ◽  
Major Public Health Problem ◽  
District Health ◽  
Active Case

Background: Measles is highly contagious vaccine preventable disease (VPD), and a major public health problem considered as leading cause of morbidity and mortality in developing countries like Pakistan. An outbreak of measles was reported in Sharifabad Islamabad on 15th of April 2017, and an investigation was launched to assess the magnitude of outbreak, evaluate risk factors and recommend control measures. Methods: A comprehensive house to house active case search along with vaccine coverage survey was conducted from April 19-22, 2017. A case was defined as "onset of maculopapular rash with fever in a resident of Sharifabad with at least one of the following signs/ symptoms, Coryza, Conjunctivitis, Cough, Otitis media or Pneumonia present in between 19 March to 22nd April 2017". Four age & sex matched controls were selected from the neighborhood. Data was collected through interview method using structured questionnaire and vaccination coverage was determined by using Epi survey form. Blood samples were sent for laboratory confirmation. Results: A total of eight cases were identified through active case finding while three were reported by local practitioner. Mean age of cases were 20 months (range 8-36 months). Severely affected age-group was 1-2 years with attack rate of 46%. Around two-third (64%) of cases and a few (16%) of controls were unvaccinated against measles. Contact with measles patient [OR 25.2, CI 3.9-160.1, P=0.00], unvaccinated children [OR 9.2 CI 2.12-40.4, P=0.000], social misconception regarding vaccination [OR 7.8 CI 1.42-42.6, P=0.00], and distance from healthcare facility [OR 5.7 CI 1.15-28.35, P=0.02] were significant risk factors. Vaccine efficacy was 90%. Conclusion: Main reasons of the outbreak were contact with the cases, and low vaccination status. We recommended comprehensive measles vaccination and community awareness sessions. On our recommendations district health authority Islamabad carried out mop up of whole area.

scholarly journals COVID-19 Vaccine Intention among Healthcare Workers in Saudi Arabia: A Cross-Sectional Survey

Vaccines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 835
Author(s):  
Mohammed Noushad ◽  
Mohammad Zakaria Nassani ◽  
Anas B. Alsalhani ◽  
Pradeep Koppolu ◽  
Fayez Hussain Niazi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Healthcare System ◽  
Healthcare Workers ◽  
Vaccine Coverage ◽  
Vaccination Campaign ◽  
Herd Immunity ◽  
Positive Sign ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Public Health Strategies

The COVID-19 pandemic has caused largescale morbidity and mortality and a tremendous burden on the healthcare system. Healthcare workers (HCWs) require adequate protection to avoid onward transmission and minimize burden on the healthcare system. Moreover, HCWs can also influence the general public into accepting the COVID-19 vaccine. Therefore, determining COVID-19 vaccine intention among HCWs is of paramount importance to plan tailor-made public health strategies to maximize vaccine coverage. A structured questionnaire was administered in February and March 2021 among HCWs in Saudi Arabia using convenience sampling, proceeding the launch of the vaccination campaign. HCWs from all administrative regions of Saudi Arabia were included in the study. In total, 674 out of 1124 HCWs responded and completed the survey (response rate 59.9%). About 65 percent of the HCWs intended to get vaccinated. The intention to vaccinate was significantly higher among HCWs 50 years of age or older, Saudi nationals and those who followed the updates about COVID-19 vaccines (p < 0.05). The high percentage (26 percent) of those who were undecided in getting vaccinated is a positive sign. As the vaccination campaign gathers pace, the attitude is expected to change over time. Emphasis should be on planning healthcare strategies to convince the undecided HCWs into accepting the vaccine in order to achieve the coverage required to achieve herd immunity.

scholarly journals Use of surveys to evaluate an integrated oral cholera vaccine campaign in response to a cholera outbreak in Hoima district, Uganda

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e038464
Author(s):  
Godfrey Bwire ◽  
Mellisa Roskosky ◽  
Anne Ballard ◽  
W Abdullah Brooks ◽  
Alfred Okello ◽  
...  
Keyword(s):  
Staff Training ◽  
Vaccine Coverage ◽  
Vaccination Campaign ◽  
Cholera Vaccine ◽  
Cholera Outbreak ◽  
Staff Members ◽  
Skill Gaps ◽  
Post Test ◽  
Oral Cholera Vaccine ◽  
Coverage Rates

ObjectivesTo evaluate the quality and coverage of the campaign to distribute oral cholera vaccine (OCV) during a cholera outbreak in Hoima, Uganda to guide future campaigns of cholera vaccine.DesignSurvey of communities targeted for vaccination to determine vaccine coverage rates and perceptions of the vaccination campaign, and a separate survey of vaccine staff who carried out the campaign.SettingHoima district, Uganda.ParticipantsRepresentative clusters of households residing in the communities targeted for vaccination and staff members who conducted the vaccine campaign.ResultsAmong 209 households (1274 individuals) included in the coverage survey, 1193 (94%; 95% CI 92% to 95%) reported receiving at least one OCV dose and 998 (78%; 95% CI 76% to 81%) reported receiving two doses. Among vaccinated individuals, minor complaints were reported by 71 persons (5.6%). Individuals with ‘some’ education (primary school or above) were more knowledgeable regarding the required OCV doses compared with non-educated (p=0.03). Factors negatively associated with campaign implementation included community sensitisation time, staff payment and problems with field transport. Although the campaign was carried out quickly, the outbreak was over before the campaign started. Most staff involved in the campaign (93%) were knowledgeable about cholera control; however, 29% did not clearly understand how to detect and manage adverse events following immunisation.ConclusionThe campaign achieved high OCV coverage, but the surveys provided insights for improvement. To achieve high vaccine coverage, more effort is needed for community sensitisation, and additional resources for staff transportation and timely payment for campaign staff is required. Pretest and post-test assessment of staff training can identify and address knowledge and skill gaps.

scholarly journals Impact of national influenza vaccination strategy in severe influenza outcomes among the high-risk Portuguese population

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ausenda Machado ◽  
Irina Kislaya ◽  
Amparo Larrauri ◽  
Carlos Matias Dias ◽  
Baltazar Nunes
Keyword(s):  
High Risk ◽  
Influenza Vaccination ◽  
Seasonal Influenza ◽  
Vaccine Coverage ◽  
Vaccination Strategy ◽  
High Risk Population ◽  
Risk Population ◽  
Seasonal Influenza Vaccination ◽  
Severe Influenza ◽  
The Impact

Abstract Background All aged individuals with a chronic condition and those with 65 and more years are at increased risk of severe influenza post-infection complications. There is limited research on cases averted by the yearly vaccination programs in high-risk individuals. The objective was to estimate the impact of trivalent seasonal influenza vaccination on averted hospitalizations and death among the high-risk population in Portugal. Methods The impact of trivalent seasonal influenza vaccination was estimated using vaccine coverage, vaccine effectiveness and the number of influenza-related hospitalizations and deaths. The number of averted events (NAE), prevented fraction (PF) and number needed to vaccinate (NVN) were estimated for seasons 2014/15 to 2016/17. Results The vaccination strategy averted on average approximately 1833 hospitalizations and 383 deaths per season. Highest NAE was observed in the ≥65 years population (85% of hospitalizations and 95% deaths) and in the 2016/17 season (1957 hospitalizations and 439 deaths). On average, seasonal vaccination prevented 21% of hospitalizations in the population aged 65 and more, and 18.5% in the population with chronic conditions. The vaccination also prevented 29% and 19.5% of deaths in each group of the high-risk population. It would be needed to vaccinate 3360 high-risk individuals, to prevent one hospitalization and 60,471 high-risk individuals to prevent one death. Conclusion The yearly influenza vaccination campaigns had a sustained positive benefit for the high-risk population, reducing hospitalizations and deaths. These results can support public health plans toward increased vaccine coverage in high-risk groups.

scholarly journals Secondary sources of negative symptoms in those meeting criteria for a clinical high-risk syndrome

2021 ◽  
Author(s):  
Tina Gupta ◽  
Gregory P. Strauss ◽  
Henry R. Cowan ◽  
Andrea Pelletier-Baldelli ◽  
Lauren M. Ellman ◽  
...  
Keyword(s):  
High Risk ◽  
Negative Symptoms ◽  
Clinical High Risk ◽  
Secondary Sources

scholarly journals Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program

2014 ◽  
Vol 22 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Everton Faccini Augusto ◽  
Larissa Silva dos Santos ◽  
Ledy do Horto dos Santos Oliveira
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
High Risk ◽  
Health Program ◽  
Vaccine Coverage ◽  
Family Health ◽  
Polymorphism Analysis ◽  
Genotype Distribution ◽  
Cross Sectional Survey ◽  
Family Health Program

OBJECTIVES: to survey the prevalence of human papillomavirus, associated risk factors and genotype distribution in women who were referred to cervical cancer screening when attended in a Family Health Program. METHOD: we conducted a cross-sectional survey, investigating 351 women. Polymerase chain reaction for DNA amplification and restriction fragment length polymorphism analysis were used to detect and typify the papillomavirus. RESULTS: virus infection was detected in 8.8% of the samples. Among the 21 different genotypes identified in this study, 14 were high risk for cervical cancer, and the type 16 was the most prevalent type. The infection was associated with women who had non-stable sexual partners. Low risk types were associated with younger women, while the high risk group was linked to altered cytology. CONCLUSION: in this sample attended a Family Health Program, we found a low rate of papillomavirus infection. Virus frequency was associated to sexual behavior. However, the broad range of genotypes detected deserves attention regarding the vaccine coverage, which includes only HPV prevalent types.

scholarly journals Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England

2021 ◽  
pp. eabg4262
Author(s):  
Edward S. Knock ◽  
Lilith K. Whittles ◽  
John A. Lees ◽  
Pablo N. Perez-Guzman ◽  
Robert Verity ◽  
...  
Keyword(s):  
Clinical Care ◽  
Vaccination Campaign ◽  
Herd Immunity ◽  
Credible Interval ◽  
The Elderly ◽  
Surveillance Data ◽  
Control Measures ◽  
Care Homes ◽  
High Coverage ◽  
Degree Of Protection

We fitted a model of SARS-CoV-2 transmission in care homes and the community to regional surveillance data for England. Compared with other approaches, our model provides a synthesis of multiple surveillance data streams into a single coherent modelling framework allowing transmission and severity to be disentangled from features of the surveillance system. Of the control measures implemented, only national lockdown brought the reproduction number (Rteff) below 1 consistently; if introduced one week earlier it could have reduced deaths in the first wave from an estimated 48,600 to 25,600 (95% credible interval [95%CrI]: 15,900–38,400). The infection fatality ratio decreased from 1.00% (95%CrI: 0.85%–1.21%) to 0.79% (95%CrI: 0.63%–0.99%), suggesting improved clinical care. The infection fatality ratio was higher in the elderly residing in care homes (23.3%, 95%CrI: 14.7%–35.2%) than those residing in the community (7.9%, 95%CrI: 5.9%–10.3%). On 2nd December 2020 England was still far from herd immunity, with regional cumulative infection incidence between 7.6% (95%CrI: 5.4%–10.2%) and 22.3% (95%CrI: 19.4%–25.4%) of the population. Therefore, any vaccination campaign will need to achieve high coverage and a high degree of protection in vaccinated individuals to allow non-pharmaceutical interventions to be lifted without a resurgence of transmission.

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