Pilot Study on the Impact of the Mediterranean Diet and Intermittent Fasting

2019 ◽  
Author(s):  
Keyword(s):  
Pilot Study ◽  
Mediterranean Diet ◽  
Intermittent Fasting ◽  
The Mediterranean ◽  
The Impact

scholarly journals Sex-Related Differences in the Effects of the Mediterranean Diet on Glucose and Insulin Homeostasis

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Alexandra Bédard ◽  
Louise Corneau ◽  
Benoît Lamarche ◽  
Sylvie Dodin ◽  
Simone Lemieux
Keyword(s):  
Sex Differences ◽  
Insulin Sensitivity ◽  
Mediterranean Diet ◽  
Sex Difference ◽  
Premenopausal Women ◽  
Nonesterified Fatty Acids ◽  
Time Interaction ◽  
Insulin Homeostasis ◽  
The Mediterranean ◽  
The Impact

Objective. To document sex differences in the impact of the Mediterranean diet (MedDiet) on glucose/insulin homeostasis and to verify whether these sex-related effects were associated with changes in nonesterified fatty acids (NEFA).Methods. All foods were provided to 38 men and 32 premenopausal women (24–53 y) during 4 weeks. Variables were measured during a 180 min OGTT before and after the MedDiet.Results. A sex-by-time interaction for plasma insulin iAUC was found (men: −17.8%,P=0.02; women: +9.4%,P=0.63;Pfor sex-by-time interaction = 0.005). A sex-by-time interaction was also observed for insulin sensitivity (Cederholm index,P=0.03), for which only men experienced improvements (men: +8.1%,P=0.047; women: −5.9%,P=0.94). No sex difference was observed for glucose and C-peptide responses. Trends toward a decrease in NEFA AUC (P=0.06) and an increase in NEFA suppression rate (P=0.06) were noted, with no sex difference. Changes in NEFA were not associated with change in insulin sensitivity.Conclusions. Results suggest that the more favorable changes in glucose/insulin homeostasis observed in men compared to women in response to the MedDiet are not explained by sex differences in NEFA response. This clinical trial is registered with clinicaltrials.govNCT01293344.

scholarly journals Self-Perceived Physical Activity and Adherence to the Mediterranean Diet in Healthy Adolescents during COVID-19: Findings from the DIMENU Pilot Study

Healthcare ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 622
Author(s):  
Angelo Galluccio ◽  
Giovanna Caparello ◽  
Ennio Avolio ◽  
Emanuele Manes ◽  
Simona Ferraro ◽  
...  
Keyword(s):  
Physical Activity ◽  
Mediterranean Diet ◽  
Eating Habits ◽  
Wellness Programs ◽  
Health Impact ◽  
The Self ◽  
Global Pandemic ◽  
Mediterranean Diet Adherence ◽  
The Mediterranean ◽  
The Impact

The global pandemic coronavirus disease (COVID-19) resulted in restrictions which forced adolescents to stay at home and influenced their food habits and lifestyles with potential negative health impact. This study aims to investigate the self-reported physical activity (PA) and eating habits related to the consumption of Mediterranean foods in a sample of adolescents during the COVID-19 lockdown enrolled into the DIMENU study. A web survey was launched for 91 adolescents (aged 15–17 years) to assess their adherence to the Mediterranean Diet using the KIDMED test and lifestyle habits using a questionnaire designed following recommendations by Italian National Institute of Health (ISS score). Our results indicate that most of the sample declared no changes in eating habits and PA without sex differences. After dividing the sample into active and sedentary groups based on the self-perceived PA, we found that KIDMED and ISS scores were significantly higher (p = 0.0028 and p = 0.0001, respectively) in active adolescents. Moreover, KIDMED was positively correlated with ISS only in active adolescents (r = 0.311, p = 0.0185). In conclusion, our data underline the impact of the PA on the Mediterranean diet adherence in adolescents during the lockdown, suggesting the usefulness of promoting wellness programs directed towards inactive individuals to increase their awareness on the importance of healthy lifestyles.

Does adherence to the Mediterranean diet modify the impact of smoking on health?

Public Health ◽  
2009 ◽  
Vol 123 (6) ◽  
pp. 459-460 ◽  
Author(s):  
C.I. Vardavas ◽  
A. Papadaki ◽  
W.H.M. Saris ◽  
A.G. Kafatos
Keyword(s):  
Mediterranean Diet ◽  
The Mediterranean ◽  
The Impact

scholarly journals Effects of Olive Oil on Blood Pressure: Epidemiological, Clinical, and Mechanistic Evidence

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1548 ◽  
Author(s):  
Marika Massaro ◽  
Egeria Scoditti ◽  
Maria Annunziata Carluccio ◽  
Nadia Calabriso ◽  
Giuseppe Santarpino ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Olive Oil ◽  
Mediterranean Diet ◽  
Lifestyle Changes ◽  
Antihypertensive Medications ◽  
Hypertensive Patients ◽  
High Oleic ◽  
The Mediterranean ◽  
The Impact

The increasing access to antihypertensive medications has improved longevity and quality of life in hypertensive patients. Nevertheless, hypertension still remains a major risk factor for stroke and myocardial infarction, suggesting the need to implement management of pre- and hypertensive patients. In addition to antihypertensive medications, lifestyle changes, including healthier dietary patterns, such as the Dietary Approaches to Stop Hypertension (DASH) and the Mediterranean diet, have been shown to favorably affect blood pressure and are now recommended as integrative tools in hypertension management. An analysis of the effects of nutritional components of the Mediterranean diet(s) on blood pressure has therefore become mandatory. After a literature review of the impact of Mediterranean diet(s) on cardiovascular risk factors, we here analyze the effects of olive oil and its major components on blood pressure in healthy and cardiovascular disease individuals and examine underlying mechanisms of action. Both experimental and human studies agree in showing anti-hypertensive effects of olive oil. We conclude that due to its high oleic acid and antioxidant polyphenol content, the consumption of olive oil may be advised as the optimal fat choice in the management protocols for hypertension in both healthy and cardiovascular disease patients.

scholarly journals From the Table to the Tumor: The Role of Mediterranean and Western Dietary Patterns in Shifting Microbial-Mediated Signaling to Impact Breast Cancer Risk

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2565 ◽  
Author(s):  
Tiffany M. Newman ◽  
Mara Z. Vitolins ◽  
Katherine L. Cook
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Mediterranean Diet ◽  
Dietary Patterns ◽  
Gut Microbiome ◽  
Western Diet ◽  
Diet Pattern ◽  
The Mediterranean ◽  
The Impact

Diet is a modifiable component of lifestyle that could influence breast cancer development. The Mediterranean dietary pattern is considered one of the healthiest of all dietary patterns. Adherence to the Mediterranean diet protects against diabetes, cardiovascular disease, and cancer. Reported consumption of a Mediterranean diet pattern was associated with lower breast cancer risk for women with all subtypes of breast cancer, and a Western diet pattern was associated with greater risk. In this review, we contrast the available epidemiological breast cancer data, comparing the impact of consuming a Mediterranean diet to the Western diet. Furthermore, we will review the preclinical data highlighting the anticancer molecular mechanism of Mediterranean diet consumption in both cancer prevention and therapeutic outcomes. Diet composition is a major constituent shaping the gut microbiome. Distinct patterns of gut microbiota composition are associated with the habitual consumption of animal fats, high-fiber diets, and vegetable-based diets. We will review the impact of Mediterranean diet on the gut microbiome and inflammation. Outside of the gut, we recently demonstrated that Mediterranean diet consumption led to distinct microbiota shifts in the mammary gland tissue, suggesting possible anticancer effects by diet on breast-specific microbiome. Taken together, these data support the anti-breast-cancer impact of Mediterranean diet consumption.

scholarly journals Science and Healthy Meals in the World: Nutritional Epigenomics and Nutrigenetics of the Mediterranean Diet

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1748 ◽  
Author(s):  
Fabio Caradonna ◽  
Ornella Consiglio ◽  
Claudio Luparello ◽  
Carla Gentile
Keyword(s):  
Mediterranean Diet ◽  
Disease Risk ◽  
Cooking Methods ◽  
Intangible Cultural Heritage ◽  
Protective Effects ◽  
Positive Health ◽  
Food Components ◽  
The Mediterranean ◽  
The Impact ◽  
Scientific Topic

The Mediterranean Diet (MD), UNESCO Intangible Cultural Heritage of Humanity, has become a scientific topic of high interest due to its health benefits. The aim of this review is to pick up selected studies that report nutrigenomic or nutrigenetic data and recapitulate some of the biochemical/genomic/genetic aspects involved in the positive health effects of the MD. These include (i) the antioxidative potential of its constituents with protective effects against several diseases; (ii) the epigenetic and epigenomic effects exerted by food components, such as Indacaxanthin, Sulforaphane, and 3-Hydroxytyrosol among others, and their involvement in the modulation of miRNA expression; (iii) the existence of predisposing or protective human genotypes due to allelic diversities and the impact of the MD on disease risk. A part of the review is dedicated to the nutrigenomic effects of the main cooking methods used in the MD and also to a comparative analysis of the nutrigenomic properties of the MD and other diet regimens and non-MD-related aliments. Taking all the data into account, the traditional MD emerges as a diet with a high antioxidant and nutrigenomic modulation power, which is an example of the “Environment-Livings-Environment” relationship and an excellent patchwork of interconnected biological actions working toward human health.

scholarly journals Neutrophil-to-Lymphocyte Ratio, Mediterranean Diet, and Bone Health in Coeliac Disease Patients: A Pilot Study

2019 ◽  
Vol 2019 ◽  
pp. 1-14 ◽  
Author(s):  
Francesca Palmacci ◽  
Elisabetta Toti ◽  
Anna Raguzzini ◽  
Giovina Catasta ◽  
Paola Aiello ◽  
...  
Keyword(s):  
Pilot Study ◽  
Coeliac Disease ◽  
Mediterranean Diet ◽  
Neutrophil To Lymphocyte Ratio ◽  
Dietary Habit ◽  
Food Groups ◽  
Mineral Density ◽  
Lymphocyte Ratio ◽  
The Mediterranean ◽  
The Relationship

Neutrophil-to-lymphocyte ratio (NLR) has been proposed as a bone loss index in postmenopausal women and as a marker of inflammation in coeliac patients. The aims of this work were to evaluate the effect of gluten-free diet (GFD) on NLR retrospectively and study the relationship between NLR and Mediterranean diet adherence and selected food groups (fruits, vegetables, red meat, potatoes, and unrefined and refined cereals). Adult individuals (n=50), who had been on a strict GFD by at least 6 months, were recruited. The degree of adherence to the Mediterranean diet was calculated with two different scores: the Mediterranean Diet Score (MDS-14), assessed through the validated 14-item questionnaire of the PREDIMED study, and the MEDScore (Score-55) proposed by Panagiotakos. The latter includes the consumption of unrefined cereals (UC). High percentages of osteopenia and osteoporosis were found within the recruited subjects, who furnished the reports of bone mineral density (BMD), in particular in postmenopausal (Post-M) women. Recent NLR was higher in subjects with osteoporosis compared to osteopenia and normal BMD. However, retrospective analysis showed both increase and decrease in NLR after GFD, with no significant differences between Marsh grade, anemia, and BMD status. Moreover, premenopausal previous pregnancy (Pre-MPP) and Post-M had higher NLR at diagnosis compared to Men and premenopausal (Pre-M), but higher differences were observed in recent NLR between Pre-MPP and Men only. Chocolate consumption was associated with lower recent NLR, whereas the latter was correlated with Score-55, but not with MDS-14. Moreover, refined cereal consumption was correlated with recent NLR. Although large prospective studies are needed in order to clarify the relationship between UC and NLR in coeliac patients, in this pilot study, we have investigated for the first time the relationship between NLR, dietary habit, and osteoporosis in coeliac disease.

scholarly journals Overview of Human Intervention Studies Evaluating the Impact of the Mediterranean Diet on Markers of DNA Damage

Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 391 ◽  
Author(s):  
Cristian Del Bo' ◽  
Mirko Marino ◽  
Daniela Martini ◽  
Massimiliano Tucci ◽  
Salvatore Ciappellano ◽  
...  
Keyword(s):  
Dna Damage ◽  
Dna Repair ◽  
Telomere Length ◽  
Mediterranean Diet ◽  
Intervention Studies ◽  
Human Intervention ◽  
Repair Gene ◽  
Dna Repair Gene ◽  
The Mediterranean ◽  
The Impact

The Mediterranean diet (MD) is characterized by high consumption of fruits, vegetables, cereals, potatoes, poultry, beans, nuts, lean fish, dairy products, small quantities of red meat, moderate alcohol consumption, and olive oil. Most of these foods are rich sources of bioactive compounds which may play a role in the protection of oxidative stress including DNA damage. The present review provides a summary of the evidence deriving from human intervention studies aimed at evaluating the impact of Mediterranean diet on markers of DNA damage, DNA repair, and telomere length. The few results available show a general protective effect of MD alone, or in combination with bioactive-rich foods, on DNA damage. In particular, the studies reported a reduction in the levels of 8-hydroxy-2′–deoxyguanosine and a modulation of DNA repair gene expression and telomere length. In conclusion, despite the limited literature available, the results obtained seem to support the beneficial effects of MD dietary pattern in the protection against DNA damage susceptibility. However, further well-controlled interventions are desirable in order to confirm the results obtained and provide evidence-based conclusions.

scholarly journals Benefits of the Mediterranean Diet in the Prevention of Non-communicable Diseases as the Epidemic of the 21st century

2013 ◽  
Vol 41 (1) ◽  
pp. 21 ◽  
Author(s):  
Doina A. TODEA ◽  
Loredana Elena ROSCA ◽  
Andreea C. COMAN ◽  
Iuliu SUATEAN ◽  
Andreea C. HERESCU
Keyword(s):  
Mediterranean Diet ◽  
21St Century ◽  
Warning Signal ◽  
Good Health ◽  
Communicable Diseases ◽  
Non Communicable Diseases ◽  
Balanced Diet ◽  
Food Pyramid ◽  
The Mediterranean ◽  
The Impact

Non-communicable diseases are known as the epidemic of the 21st century. In Romania, these are responsible for almost 91% of all the deaths. A balanced diet and regular physical activity (at least 30 minutes throughout the day) are the keys to a healthy and long living life. Mediterranean diet is shown to be the optimal diet for preventing non-communicable diseases and preserving good health. The concept of the Mediterranean diet is defined by the food pyramid, which is meant to provide an overall impression of healthy food choices, rather than to define recommended weights of certain foods or proportions of energy obtained from them. In Romania the concept of Mediterranean diet is unknown to most ordinary people. Even in medicine field there are few doctors who really know about this diet and its effects on patients’ health. Our purpose in writing this article was to draw a warning signal about the impact of Mediterranean diet on the health of people, in hope that through media, the importance of a healthy and active life in raising quality of life and decreasing morbidity and mortality can be fully understood.

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