Events of elevated somatic cell counts in high-producing dairy cows are associated with daily body weight loss in early lactation

To investigate if leptin shares in vivo activities with interleukin (IL)-6 family cytokines, it was tested in normal mice for the ability, after a single injection, to induce the acute-phase protein serum amyloid A, to potentiate the induction by IL-1 of serum corticosterone and IL-6, and to inhibit the induction by lipopolysaccharide of serum tumor necrosis factor and, after seven daily injections, to cause body weight loss and to change peripheral blood cell counts. At a 0.5 mg/kg dose, leptin caused body weight loss but did not show any of the other activities above. At a dose of 5 mg/kg, which also caused body weight loss, leptin potentiated the induction by IL-1 of serum corticosterone and IL-6 but did not show any other activity. In addition to causing body weight loss, leptin shows only some of the in vivo activities typical of IL-6 family cytokines and only if used at a dose that exceeds the one sufficient to affect body weight. In vivo, leptin seems to chiefly control body weight and not inflammatory or hematopoietic processes.

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Association of paratuberculosis sero-status with milk production and somatic cell counts across 5 lactations, using multilevel mixed models, in dairy cows

Journal of Dairy Science ◽

10.3168/jds.2017-13746 ◽

2018 ◽

Vol 101 (8) ◽

pp. 7638-7649 ◽

Cited By ~ 3

Author(s):

E.G. Martins ◽

P. Oliveira ◽

B.M. Oliveira ◽

D. Mendonça ◽

J. Niza-Ribeiro

Keyword(s):

Dairy Cows ◽

Somatic Cell ◽

Milk Production ◽

Mixed Models ◽

Somatic Cell Counts ◽

Cell Counts

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Spatial patterns of recorded mastitis incidence and somatic cell counts in Swedish dairy cows: implications for surveillance

Geospatial health ◽

10.4081/gh.2011.163 ◽

2011 ◽

Vol 6 (1) ◽

pp. 117 ◽

Cited By ~ 2

Author(s):

Cecilia Wolff ◽

Mark Stevenson ◽

Ulf Emanuelson ◽

Agneta Egenvall ◽

Ann Lindberg

Keyword(s):

Dairy Cows ◽

Somatic Cell ◽

Spatial Patterns ◽

Somatic Cell Counts ◽

Cell Counts ◽

Swedish Dairy

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Prediction of total quarter milk somatic cell counts based on foremilk sampling

Journal of Dairy Research ◽

10.1017/s0022029909004166 ◽

2009 ◽

Vol 76 (3) ◽

pp. 326-330 ◽

Cited By ~ 5

Author(s):

Olga Wellnitz ◽

Marcus G Doherr ◽

Marta Woloszyn ◽

Rupert M Bruckmaier

Keyword(s):

Dairy Cows ◽

Somatic Cell ◽

Cell Count ◽

Somatic Cell Count ◽

Practical Reasons ◽

Udder Health ◽

Somatic Cell Counts ◽

Cell Numbers ◽

Cell Counts

Determination of somatic cell count (SCC) is used worldwide in dairy practice to describe the hygienic status of the milk and the udder health of cows. When SCC is tested on a quarter level to detect single quarters with high SCC levels of cows for practical reasons, mostly foremilk samples after prestimulation (i.e. cleaning of the udder) are used. However, SCC is usually different in different milk fractions. Therefore, the goal of this study was the investigation of the use of foremilk samples for the estimation of total quarter SCC. A total of 378 milkings in 19 dairy cows were performed with a special milking device to drain quarter milk separately. Foremilk samples were taken after udder stimulation and before cluster attachment. SCC was measured in foremilk samples and in total quarter milk. Total quarter milk SCC could not be predicted precisely from foremilk SCC measurements. At relatively high foremilk SCC levels (>300×103 cells/ml) foremilk SCC were higher than total quarter milk. At around (50–300)×103 cells/ml foremilk and total quarter SCC did not differ considerably. Most interestingly, if foremilk SCC was lower than 50×103 cells/ml the total quarter SCC was higher than foremilk SCC. In addition, individual cows showed dramatic variations in foremilk SCC that were not very well related to total quarter milk SCC. In conclusion, foremilk samples are useful to detect high quarter milk SCC to recognize possibly infected quarters, only if precise cell counts are not required. However, foremilk samples can be deceptive if very low cell numbers are to be detected.

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