A Novel and Convenient Synthesis of 3-Amino-2H-1,2,4-Triazoles from Isoselenocyanates and Hydrazine Hydrate

2018 ◽  
Vol 42 (5) ◽  
pp. 255-259
Author(s):  
Xue Li ◽  
Zhixiang Peng ◽  
Yuanyuan Zhang ◽  
Jiangwei Wang ◽  
Bin Gan ◽  
...  
Keyword(s):  
Hydrazine Hydrate ◽  
Aromatic Amine ◽  
Atom Economy ◽  
One Pot ◽  
One Pot Synthesis ◽  
Convenient Synthesis ◽  
Plausible Mechanism

A novel and convenient one-pot synthesis of 3-amino-2 H-1,2,4-triazoles from two molecules of isoselenocyanates and hydrazine hydrate via cyclodeselenisation was developed. Various 3-amino-2 H-1,2,4-triazoles were obtained in moderate to good yields (33–45%, based on isoselenocyanates). The selenium powder and aromatic amine side products during the reaction could be recycled for efficient preparation of isoselenocyanates, which improved the atom economy. A plausible mechanism was proposed for the formation of the target products.

Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanide-based Three-component Reaction

2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja
Keyword(s):  
Efficient Method ◽  
Atom Economy ◽  
Reaction Conditions ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.

One-pot synthesis of sulfonylhydrazones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water

2021 ◽  
Author(s):  
Mengqiang Luo ◽  
Hai Wang ◽  
Xiaorong Ren ◽  
Ruijuan Lu ◽  
Chenze Qi ◽  
...  
Keyword(s):  
Hydrazine Hydrate ◽  
Sulfonyl Chloride ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals One-Pot Eco-Safe Saccharin-Catalyzed Procedure for Expedient and Convenient Synthesis of Dihydropyrano[2,3-c]pyrazole, Tetrahydrobenzo[b]pyran and Pyrano[2,3-d]pyrimidinone Scaffolds as a Green and Versatile Catalyst

2018 ◽  
Vol 18 (1) ◽  
pp. 7
Author(s):  
Farzaneh Mohamadpour ◽  
Mojtaba Lashkari ◽  
Nourallah Hazeri
Keyword(s):  
Reaction Times ◽  
Atom Economy ◽  
One Pot ◽  
Convenient Synthesis ◽  
Cyclocondensation Reaction ◽  
The One

A green and facile saccharin-catalyzed procedure is developed for the one-pot convenient synthesis of dihydropyrano[2,3-c]pyrazole, tetrahydrobenzo[b]pyran and pyrano[2,3-d]pyrimidinone scaffolds via multi-component tandem Knoevenagel cyclocondensation reaction. This procedure has the chief advantages of green, inexpensive and readily available catalyst, high atom-economy, high to quantitative yields and the reaction procedure is mild and involves facile workup procedure to obtain the desired products in short reaction times.

One-pot synthesis of β-ketosulfones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water

Tetrahedron ◽  
2020 ◽  
Vol 76 (48) ◽  
pp. 131635
Author(s):  
Yaohong Zhang ◽  
Mengqiang Luo ◽  
Yan Li ◽  
Runfu Shen ◽  
Chenze Qi ◽  
...  
Keyword(s):  
Hydrazine Hydrate ◽  
Sulfonyl Chloride ◽  
One Pot ◽  
One Pot Synthesis

DABCO as a green catalyst for the synthesis of pyranoquinoline derivatives

2017 ◽  
Vol 95 (5) ◽  
pp. 601-604 ◽  
Author(s):  
Ramin Ghorbani-Vaghei ◽  
Farid Rahmatpour ◽  
Narges Sarmast ◽  
Jafar Mahmoudi ◽  
Azadeh Shahriari
Keyword(s):  
One Pot ◽  
Green Catalyst ◽  
One Pot Synthesis ◽  
Convenient Synthesis ◽  
High Yields

In this study, a rapid and convenient synthesis of quinolines was developed. The reaction involves a one-pot synthesis of pyranoquinoline derivatives from aldehyde, malonitrile, and 8-hydroxyquinoline using DABCO as a catalyst at 80 °C in H2O/EtOH as the solvent in good to high yields.

Nano-SiO2: a heterogeneous and reusable catalyst for the one-pot synthesis of symmetrical and unsymmetrical 3,3-di(aryl)indolin-2-ones under solvent-free conditions

2016 ◽  
Vol 71 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Kobra Nikoofar ◽  
Zahra Khalili
Keyword(s):  
Room Temperature ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
One Pot ◽  
Nano Sio2 ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Magnetic Stirring ◽  
Plausible Mechanism ◽  
The One

AbstractSymmetrical and unsymmetrical 3,3-di(aryl)indolin-2-ones have been synthesized by nano-SiO2 as green, heterogeneous, and reusable catalyst under solvent-free conditions at room temperature via magnetic stirring and grinding methods. A plausible mechanism of condensation has also been presented.

scholarly journals A Convenient Synthesis of Substituted Spiro[5.5]Undecanes Using Lewis Acid Catalysts

2012 ◽  
Vol 60 (1) ◽  
pp. 121-124 ◽  
Author(s):  
M Glasuddin Ahmed ◽  
UKR Romman ◽  
Kawsari Akhter ◽  
Monarul Islam ◽  
Mohammad Mosharrag Hossain ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Michael Reaction ◽  
Acid Catalysts ◽  
Lewis Acid Catalysts ◽  
One Pot ◽  
One Pot Synthesis ◽  
Convenient Synthesis

A one-pot synthesis of 3, 3-Dimethyl-7, 11-diphenyl-spiro [5, 5] undecane-1, 5, 9-triones 4a-c has been achieved by the application of Michael reaction between dimedone (5,5-dimethylcyclohexane-1,3-dione) 1 and trans,trans diarylideneacetones [1,5-diaryl-1,4- pentadien-3-ones] 2a-c (a. Ar = C6H5-, b. Ar = 2-Cl-C6H4-, c. Ar = 2- CH3O- C6H4) using Lewis acid catalysts.DOI: http://dx.doi.org/10.3329/dujs.v60i1.10349  Dhaka Univ. J. Sci. 60(1): 121-124 2012 (January)

A facile one-pot synthesis of aryl-substituted fused pyrimidinones

2016 ◽  
Vol 22 (2) ◽  
pp. 59-62 ◽  
Author(s):  
Hyuck Joo Lee ◽  
Yang-Heon Song
Keyword(s):  
Biological Activity ◽  
One Pot ◽  
One Pot Synthesis ◽  
Convenient Synthesis

AbstractThe convenient synthesis of a series of 3-phenylpyrido[1,2-a]pyrimidinones 4, 3-phenylpyrimido[1,2-c]quinazolinones 7 and 3-phenylpyrazino[1,2-a]pyrimidinones 10 with promising biological activity is presented.

Convenient synthesis of 2,3-disubstituted quinazolin-4(3H)-ones and 2-styryl-3-substituted quinazolin-4(3H)-ones: applications towards the synthesis of drugs

RSC Advances ◽  
2015 ◽  
Vol 5 (39) ◽  
pp. 30819-30825 ◽  
Author(s):  
Dinesh Kumar ◽  
Pradeep S. Jadhavar ◽  
Manesh Nautiyal ◽  
Himanshu Sharma ◽  
Prahlad K. Meena ◽  
...  
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
One Pot Synthesis ◽  
Convenient Synthesis ◽  
Solvent Free Conditions ◽  
The One

Simple, convenient, and green synthetic protocols have been developed for the one pot synthesis of 2,3-disubstituted quinazolin-4(3H)-ones and 2-styryl-3-substituted quinazolin-4(3H)-ones under catalyst and solvent free conditions.

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