scholarly journals Investigating Critical Risk Factors of Liver Cancer with Deep Neural Networks

2021 ◽  
Author(s):  
Jinpeng Li ◽  
Yaling Tao ◽  
Zhunan Li ◽  
Ting Cai

The crude incidence of liver cancer ranks top five among all cancers in China, and the death rate ranks the top two. Identifying critical risk factors of liver cancer helps people adjust their lifestyles to reduce cancer risk. Launched in 2012, Early Diagnosis and Treatment of Urban Cancer project has been carried out in major cities of China, which collected a broad range of epidemiological risk factors including definite, probable and possible causes of cancer. We retrieved data from 2014 to the present and obtained 184 liver cancer cases among 55 thousand people. We explored 84 risk factors and implemented liver cancer prediction model with machine learning algorithms, where deep neural network achieved the best performance using non-clinical information (mean AUC=0.73). We analyzed model parameters to investigate critical risk factors that contribute the most to prediction. Using 50% top-ranking risk factors to train a model, the performance showed no significant difference from that using all risk factors. Using top 10% risk factors induced a sensitivity drop and a lower false positive rate. These phenomena prove that the identified risk factors are critical in liver cancer prediction. This work is a reference in public health research, and provides a scientific lifestyle guideline for individuals to prevent liver cancer based on machine learning technology.

2012 ◽  
pp. 830-850
Author(s):  
Abhilash Alexander Miranda ◽  
Olivier Caelen ◽  
Gianluca Bontempi

This chapter presents a comprehensive scheme for automated detection of colorectal polyps in computed tomography colonography (CTC) with particular emphasis on robust learning algorithms that differentiate polyps from non-polyp shapes. The authors’ automated CTC scheme introduces two orientation independent features which encode the shape characteristics that aid in classification of polyps and non-polyps with high accuracy, low false positive rate, and low computations making the scheme suitable for colorectal cancer screening initiatives. Experiments using state-of-the-art machine learning algorithms viz., lazy learning, support vector machines, and naïve Bayes classifiers reveal the robustness of the two features in detecting polyps at 100% sensitivity for polyps with diameter greater than 10 mm while attaining total low false positive rates, respectively, of 3.05, 3.47 and 0.71 per CTC dataset at specificities above 99% when tested on 58 CTC datasets. The results were validated using colonoscopy reports provided by expert radiologists.


Agriculture ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 387
Author(s):  
Nahina Islam ◽  
Md Mamunur Rashid ◽  
Santoso Wibowo ◽  
Cheng-Yuan Xu ◽  
Ahsan Morshed ◽  
...  

This paper explores the potential of machine learning algorithms for weed and crop classification from UAV images. The identification of weeds in crops is a challenging task that has been addressed through orthomosaicing of images, feature extraction and labelling of images to train machine learning algorithms. In this paper, the performances of several machine learning algorithms, random forest (RF), support vector machine (SVM) and k-nearest neighbours (KNN), are analysed to detect weeds using UAV images collected from a chilli crop field located in Australia. The evaluation metrics used in the comparison of performance were accuracy, precision, recall, false positive rate and kappa coefficient. MATLAB is used for simulating the machine learning algorithms; and the achieved weed detection accuracies are 96% using RF, 94% using SVM and 63% using KNN. Based on this study, RF and SVM algorithms are efficient and practical to use, and can be implemented easily for detecting weed from UAV images.


Wireless networks are continuously facing challenges in the field of Information Security. This leads to major researches in the area of Intrusion detection. The working of Intrusion detection is performed mainly by signature based detection and anomaly based detection. Anomaly based detection is based on the behavior of the network. One of the major challenge in this domain is to identify and detect the malicious node in wireless networks. The intrusion detection mechanism has to analyse the behavior of the node in the network by means of the several features possessed by each node. Intelligent schemes are the need of the hour in such scenario. This paper has taken a standard dataset for studying the features of the wireless node and reduced the features by applying the most efficient Correlation Attribute feature selection method. The machine learning algorithms are applied to obtain an effective training model which is then applied on the testing dataset to validate the model. The accuracy of the model is determined by the performance parameters such as true positive rate, false positive rate and ROC area. Neural network, bagging and decision tree algorithm RepTree are giving promising results in comparison with other classification algorithms.


2019 ◽  
Vol 12 (4) ◽  
pp. 294-305
Author(s):  
Balázs Szűcs ◽  
Áron Ballagi

Nowadays machine learning and artificial neural networks are hot topic. These methods gains more and more ground in everyday life. In addition to everyday usage, an increasing emphasis placed on industrial use. In the field of research and development, materials science, robotics and thanks to the spread of Industry 4.0 and digitalization, more and more machine learning based systems introduced in production. This paper gives examples of possible ways of using machine learning algorithms in manufacturing, as well as reducing pseudo-error (false positive) rate of machine vision quality control systems. Even the simplest algorithms and models can be very effective on real-world problems. With the usage of convolutional neural networks, the pseudo-error rate of the examined system reducible.


2021 ◽  
Author(s):  
Hiroaki Ito ◽  
Takashi Matsui ◽  
Ryo Konno ◽  
Makoto Itakura ◽  
Yoshio Kodera

Abstract Recent Mass spectrometry (MS)-based techniques enable deep proteome coverage with relative quantitative analysis, resulting in increased identification of very weak signals accompanied by increased data size of liquid chromatography (LC)–MS/MS spectra. However, the identification of weak signals using an assignment strategy with poorer performance resulted in imperfect quantification with misidentification of peaks and ratio distortions. Manually annotating a large number of signals within a very large dataset is not a realistic approach. In this study, therefore, we utilized machine learning algorithms to successfully extract a higher number of peptide peaks with high accuracy and precision. Our strategy evaluated each peak identified using six different algorithms; peptide peaks identified by all six algorithms (i.e., unanimously selected) were subsequently assigned as true peaks, which resulted in a reduction in the false-positive rate. Hence, exact and highly quantitative peptide peaks were obtained, providing better performance than obtained applying the conventional criteria or using a single machine learning algorithm.


Author(s):  
Abhilash Alexander Miranda ◽  
Olivier Caelen ◽  
Gianluca Bontempi

This chapter presents a comprehensive scheme for automated detection of colorectal polyps in computed tomography colonography (CTC) with particular emphasis on robust learning algorithms that differentiate polyps from non-polyp shapes. The authors’ automated CTC scheme introduces two orientation independent features which encode the shape characteristics that aid in classification of polyps and non-polyps with high accuracy, low false positive rate, and low computations making the scheme suitable for colorectal cancer screening initiatives. Experiments using state-of-the-art machine learning algorithms viz., lazy learning, support vector machines, and naïve Bayes classifiers reveal the robustness of the two features in detecting polyps at 100% sensitivity for polyps with diameter greater than 10 mm while attaining total low false positive rates, respectively, of 3.05, 3.47 and 0.71 per CTC dataset at specificities above 99% when tested on 58 CTC datasets. The results were validated using colonoscopy reports provided by expert radiologists.


Author(s):  
Ravinder Ahuja ◽  
Vishal Vivek ◽  
Manika Chandna ◽  
Shivani Virmani ◽  
Alisha Banga

An early diagnosis of insomnia can prevent further medical aids such as anger issues, heart diseases, anxiety, depression, and hypertension. Fifteen machine learning algorithms have been applied and 14 leading factors have been taken into consideration for predicting insomnia. Seven performance parameters (accuracy, kappa, the true positive rate, false positive rate, precision, f-measure, and AUC) are used and for implementation. The authors have used python language. The support vector machine is giving higher performance out of all algorithms giving accuracy 91.6%, f-measure is 92.13, and kappa is 0.83. Further, SVM is applied on another dataset of 100 patients and giving accuracy 92%. In addition, an analysis of the variable importance of CART, C5.0, decision tree, random forest, adaptive boost, and XG boost is calculated. The analysis shows that insomnia primarily depends on the factors, which are the vision problem, mobility problem, and sleep disorder. This chapter mainly finds the usages and effectiveness of machine learning algorithms in Insomnia diseases prediction.


2019 ◽  
Vol 11 (16) ◽  
pp. 4386 ◽  
Author(s):  
Pham ◽  
Shirzadi ◽  
Shahabi ◽  
Omidvar ◽  
Singh ◽  
...  

: Landslides have multidimensional effects on the socioeconomic as well as environmental conditions of the impacted areas. The aim of this study is the spatial prediction of landslide using hybrid machine learning models including bagging (BA), random subspace (RS) and rotation forest (RF) with alternating decision tree (ADTree) as base classifier in the northern part of the Pithoragarh district, Uttarakhand, Himalaya, India. To construct the database, ten conditioning factors and a total of 103 landslide locations with a ratio of 70/30 were used. The significant factors were determined by chi-square attribute evaluation (CSEA) technique. The validity of the hybrid models was assessed by true positive rate (TP Rate), false positive rate (FP Rate), recall (sensitivity), precision, F-measure and area under the receiver operatic characteristic curve (AUC). Results concluded that land cover was the most important factor while curvature had no effect on landslide occurrence in the study area and it was removed from the modelling process. Additionally, results indicated that although all ensemble models enhanced the power prediction of the ADTree classifier (AUCtraining = 0.859; AUCvalidation = 0.813); however, the RS ensemble model (AUCtraining = 0.883; AUCvalidation = 0.842) outperformed and outclassed the RF (AUCtraining = 0.871; AUCvalidation = 0.840), and the BA (AUCtraining = 0.865; AUCvalidation = 0.836) ensemble model. The obtained results would be helpful for recognizing the landslide prone areas in future to better manage and decrease the damage and negative impacts on the environment.


2017 ◽  
Author(s):  
Casey A Cole ◽  
Dien Anshari ◽  
Victoria Lambert ◽  
James F Thrasher ◽  
Homayoun Valafar

BACKGROUND Smoking is the leading cause of preventable death in the world today. Ecological research on smoking in context currently relies on self-reported smoking behavior. Emerging smartwatch technology may more objectively measure smoking behavior by automatically detecting smoking sessions using robust machine learning models. OBJECTIVE This study aimed to examine the feasibility of detecting smoking behavior using smartwatches. The second aim of this study was to compare the success of observing smoking behavior with smartwatches to that of conventional self-reporting. METHODS A convenience sample of smokers was recruited for this study. Participants (N=10) recorded 12 hours of accelerometer data using a mobile phone and smartwatch. During these 12 hours, they engaged in various daily activities, including smoking, for which they logged the beginning and end of each smoking session. Raw data were classified as either smoking or nonsmoking using a machine learning model for pattern recognition. The accuracy of the model was evaluated by comparing the output with a detailed description of a modeled smoking session. RESULTS In total, 120 hours of data were collected from participants and analyzed. The accuracy of self-reported smoking was approximately 78% (96/123). Our model was successful in detecting 100 of 123 (81%) smoking sessions recorded by participants. After eliminating sessions from the participants that did not adhere to study protocols, the true positive detection rate of the smartwatch based-detection increased to more than 90%. During the 120 hours of combined observation time, only 22 false positive smoking sessions were detected resulting in a 2.8% false positive rate. CONCLUSIONS Smartwatch technology can provide an accurate, nonintrusive means of monitoring smoking behavior in natural contexts. The use of machine learning algorithms for passively detecting smoking sessions may enrich ecological momentary assessment protocols and cessation intervention studies that often rely on self-reported behaviors and may not allow for targeted data collection and communications around smoking events.


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