Plackett-Burman matrix and response surface methodology-central composite design for optimization of Lactobacillus Acidophilus biomass production
2014 ◽
Vol 17
(2)
◽
pp. 60-72
Keyword(s):
Biomass of Lactobacillus acidophilus was optimized in the tofu wastewater medium by Plackett-Burman matrix and Response surface methodology – Central composite design (RSM-CCD). The highest biomass was 0.73 g/100mL at 106 CFU/mL of initial density of L. acidophilus in tofu wastewater medium, with 0.37% (NH4)2SO4 and 17.59% sucrose. L. acidophilus produced maximum value of biomass after 20 hours of incubation at 37°C. There was a similar proportion at 96.05% in comparison to experimental value and optimization theory, approximatly 93.58% L. acidophilus biomass in MRS medium. As a result, optimization model could be applied in biomass production of L. acidophilus to enhance comercial value and contribute to environmental protection.
2011 ◽
Vol 10
(65)
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pp. 14637-14643
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2019 ◽
Vol 7
(2)
◽
pp. 139-147
2011 ◽
Vol 62
(9-12)
◽
pp. 1013-1023
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2020 ◽
Vol 17
(11)
◽
pp. 2877-2883