scholarly journals The Difference Upper Incisor and Upper Molar Alveolar Bone Loss between Smoker and Non-Smoker Patient with Chronic Periodontitis

2019 ◽  
Vol 22 (1) ◽  
pp. 6-11
Author(s):  
Aini Hariyani Nasution ◽  
Martina Amalia ◽  
Cornelia Christy Tarigan
Keyword(s):  
Bone Loss ◽  
Chronic Periodontitis ◽  
Alveolar Bone ◽  
Alveolar Bone Loss ◽  
Oral Disease ◽  
Periodontal Pocket ◽  
Cytokine Levels ◽  
Tooth Apex ◽  
The Difference ◽  
Upper Molar

Periodontitis is one of most common oral disease. Chronic periodontitis is characterised by gingival inflamation, periodontal pocket, lost of attachment, and alveolar bone loss. Smoking is a risk factor of periodontal disease that has direct effect to periodontal tissue. Smoking prevalence in Indonesia during 2013 was about 56,7% among men and about 1,9% among women. Smoking modifies the periodontal microbial challenge and host cytokine levels. Some studies showed that smoker has greater alveolar bone loss than non-smoker, and teeth that have the greatest alveolar bone loss are incisor and followed by molar. The aim of this study is to know the upper incisor and upper molar alveolar bone loss differences between smoker and non-smoker patient with chronic periodontitis. The study’s samples are 92 chronic periodontitis statuses and 200 periapical radiographs that selected by purposive sampling techinque. This study will measure the distance between cementoenamel junction to alveolar bone crest, cementoenamel junction to tooth apex, and alveolar bone loss percentage at upper incisor and upper molar. To compare the differences upper incisor and upper molar alveolar bone loss at patient with chronic periodontitis between smoker and non-smoker will be analyzed by independent t test and Mann-Whitney U test. The result showed that smoker has greater alveolar bone loss than non-smoker. There is no significant differences at upper incisor alveolar bone loss and there is significant differences at upper molar alveolar bone loss between smoker and non-smoker patient with chronic periodontitis.

Alveolar Bone Loss of Senescence-accelerated Mouse (SAM)

1990 ◽  
Vol 69 (1) ◽  
pp. 82-86 ◽  
Author(s):  
M. Sashima ◽  
M. Satoh ◽  
A. Suzuki
Keyword(s):  
Bone Loss ◽  
Life Span ◽  
Chronic Periodontitis ◽  
Alveolar Bone ◽  
Alveolar Bone Loss ◽  
Mandibular Molars ◽  
Significant Difference ◽  
The Difference ◽  
Senescence Accelerated Mouse

SAM-R/1/Iw (senescence-accelerated mouse, resistant) and Pl2/Iw (senescence-accelerated mouse, prone) under a conventional environment and eating standard pellets were examined for alveolar bone loss and the presence of periodontitis around maxillary and mandibular molars as a function of age. Neither SAM strain manifested a chronic periodontitis similar to that in humans, and no obvious plaque and calculus were observed. However, in both strains, 15% of M3 was lost after 13 months of age, and alveolar bone loss gradually increased with advancing age. Though there was no significant difference in the incidence of M3 loss between the two strains, P/2/Iw showed a higher alveolar bone loss around all molars than did Rl1/ Iw after one month of age throughout their life span. For Ml, the difference in alveolar bone loss between Pl2/Iw and Rl1/Iw was significant, and it was probably caused by the difference in degree of molar eruption. Other factors, such as occlusal trauma and gingivitis, may play some role in alveolar bone loss.

scholarly journals Clinical Evaluation of Gutkha chewing and Pattern of Bone Loss in Periodontitis

2014 ◽  
Vol 5 (4) ◽  
pp. 199-203
Author(s):  
Harshal Liladhar Chaudhari ◽  
Nipun Ashok ◽  
Veena Kalburgi ◽  
Haziel Dina Jenifer
Keyword(s):  
Bone Loss ◽  
Clinical Evaluation ◽  
Chronic Periodontitis ◽  
Alveolar Bone ◽  
Alveolar Bone Loss ◽  
Probing Depth ◽  
Proximal Site ◽  
Almost All ◽  
Age Range ◽  
Maxillary Arch

ABSTRACT Introduction Tobacco in the form of Gutkha is commonly used in India. The present study was done to analyze the extent and pattern of alveolar bone loss (ABL) among gutkha chewers who were having chronic periodontitis. Materials and methods A total of 55 habitual gutkha chewers within the age range of 18 to 35 years with chronic periodontitis, who were otherwise healthy were recruited for the study. Fourteen full mouth intraoral periapical (IOPA) radiographs were taken for each individual (a total of 770 radiographs) with the help of radiovisiography. Kodak dental software was used to analyze and measure the alveolar bone loss at each proximal site and data were computed as percentage alveolar bone loss. Results Almost all the subjects had poor oral hygiene status. Clinical parameters of periodontal examination represented by clinical attachment level, probing depth, gingival bleeding index had positive correlation with frequency and duration of gutkha chewing. The study population had a mean alveolar bone loss of 17%. Mean bone loss was more severe in mandible 18.3% ± 2.6, when compared with maxillary arch 15.7% ± 3.7. Conclusion Maximum bone loss was observed with molars and incisors. Alveolar bone loss was more frequently found in mandibular arch as compared to maxillary arch. How to cite this article Warad S, Chaudhari HL, Ashok N, Kalburgi V, Kalburgi NB, Jenifer HD. Clinical Evaluation of Gutkha chewing and Pattern of Bone Loss in Periodontitis. World J Dent 2014;5(4):199-203.

Implantable zoledronate-PLGA microcapsules ameliorate alveolar bone loss, gingival inflammation and oxidative stress in an experimental periodontitis rat model

2020 ◽  
Vol 35 (6) ◽  
pp. 569-578
Author(s):  
Chun Yao ◽  
Qingqing Zhang ◽  
Jun Li ◽  
Peng She ◽  
Fanzhi Kong ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Bone Loss ◽  
Rat Model ◽  
Inflammatory Cytokine ◽  
Alveolar Bone ◽  
Underlying Mechanism ◽  
Alveolar Bone Loss ◽  
Gingival Inflammation ◽  
Cytokine Levels ◽  
And Oxidative Stress

The effect of implantable Zoledronate-PLGA microcapsules (PLGA-ZOL) in periodontitis remains unclear. In this study, we aimed to explore the potential role of PLGA-ZOL in protecting periodontitis and elucidate the underlying mechanism. A rat model of periodontitis was established by ligation the mandibular first molars, then PLGA-ZOL was implanted. The healing volume was scanned by cone-beam computed tomography. Cytokine levels in the gingival tissues were determined by ELISA and RT-PCR. Oxidative stress was indicated by detecting superoxide dismutase concentration and catalase activity. After periodontitis model was successfully established in rats, PLGA-ZOL treatment significantly attenuated alveolar bone loss, as indicated by the increased total healing volume, bone volume/tissue volume and osteoprotegerin level, as well as decreased sRANKL level. PLGA-ZOL treatment also suppressed the inflammatory activities by inhibiting pro-inflammatory cytokine production (TNF-α, IL-1β) but increasing anti-inflammatory cytokine secretion (IL-10). Furthermore, PLGA-ZOL was found to ameliorate oxidative stress in gingival tissues. In conclusion, PLGA-ZOL microcapsules ameliorate alveolar bone loss, gingival inflammation and oxidative stress in an experimental rat model of periodontitis.

Salivary biomarkers: Relationship between oxidative stress and alveolar bone loss in chronic periodontitis

2013 ◽  
Vol 72 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Daniela Miricescu ◽  
Alexandra Totan ◽  
Bogdan Calenic ◽  
Brandusa Mocanu ◽  
Andreea Didilescu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Bone Loss ◽  
Chronic Periodontitis ◽  
Alveolar Bone ◽  
Alveolar Bone Loss ◽  
Salivary Biomarkers

EFFECTS OF ALENDRONATE THERAPY ON CYCLOSPORINE INDUCED ALVEOLAR BONE LOSS : A MORPHO-METRIC AND BIO-CHEMICAL STUDY IN RATS

2016 ◽  
Vol 4 (4) ◽  
pp. 947-955
Author(s):  
Sneha R Bhat ◽  
◽  
Aravind R Kudva ◽  
Dhoom S Mehta ◽  
◽  
...  
Keyword(s):  
Bone Loss ◽  
Alveolar Bone ◽  
Chemical Study ◽  
Alveolar Bone Loss

3,4,5-Trihydroxybenzoic acid attenuates ligature-induced periodontal disease in Wistar rats.

2020 ◽  
Vol 19 ◽  
Author(s):  
Ozkan Karatas ◽  
Fikret Gevrek
Keyword(s):  
Bone Loss ◽  
Gallic Acid ◽  
Wistar Rats ◽  
Alveolar Bone ◽  
Alveolar Bone Loss ◽  
Collagenase Activity ◽  
Osteoblastic Activity ◽  
Cell Counts ◽  
Experimental Periodontitis ◽  
Anti Inflammatory

Background: 3,4,5-Trihydroxybenzoic acid, which is also known as gallic acid, is an anti-inflammatory agent who could provide beneficial effects in preventing periodontal inflammation. The present study aimed to evaluate the anti-inflammatory effects of gallic acid on experimental periodontitis in Wistar rats. Alveolar bone loss, osteoclastic activity, osteoblastic activity, and collagenase activity were also determined. Methods: 32 Wistar rats were used in the present study. Study groups were created as following: Healthy control (C,n=8) group; periodontitis (P,n=8) group; periodontitis and 30 mg/kg gallic acid administered group (G30,n=8); periodontitis and 60 mg/kg gallic acid administered group (G60,n=8). Experimental periodontitis was created by placing 4-0 silk sutures around the mandibular right first molar tooth. Morphological changes in alveolar bone were determined by stereomicroscopic evaluation. Mandibles were undergone histological evaluation. Matrix metalloproteinase (MMP)-8, tissue inhibitor of MMPs (TIMP)-1, bone morphogenetic protein (BMP)-2 expressions, tartrate-resistant acid phosphatase (TRAP) positive osteoclast cells, osteoblast, and inflammatory cell counts were determined. Results: Highest alveolar bone loss was observed in the periodontitis group. Both doses of gallic acid decreased alveolar bone loss compared to the P group. TRAP-positive osteoclast cell counts were higher in the P group, and gallic acid successfully lowered these counts. Osteoblast cells also increased in gallic acid administered groups. Inflammation in the P group was also higher than those of C, G30, and G60 groups supporting the role of gallic acid in preventing inflammation. 30 and 60 mg/kg doses of gallic acid decreased MMP-8 levels and increased TIMP-1 levels. BMP levels increased in gallic acid administered groups, similar to several osteoblasts. Conclusion: Present results revealed an anti-inflammatory effect of gallic acid, which was indicated by decreased alveolar bone loss and collagenase activity and increased osteoblastic activity.

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