Hearing Impairment in Children with Congenital Hypothyroidism

2021 ◽  
Vol 36 (1) ◽  
pp. 14-19
Author(s):  
Rabi Biswas ◽  
Md Rafiqul Islam
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Congenital Hypothyroidism ◽  
Middle Ear ◽  
Assessment Tool ◽  
Acoustic Emissions ◽  
Pure Tone Audiometry ◽  
Behavioral Observation ◽  
Increased Risk ◽  
Age Of Diagnosis

Background: There is increased risk of hearing impairment in children with congenital hypothyroidism (CH). Only a few studies have explored the prevalence of hearing impairment in CH and their results vary widely. There is no data of hearing impairment in Bangladeshi children with CH. Objectives: The aim of this study was to investigate the prevalence of hearing impairment in children with CH, and its relation with age of diagnosis and the dose of thyroxine (T4) they received. Methods: This study was conducted in Paediatric Endocrinology & Metabolic Disorder Department of Dhaka Shishu (Children) Hospital from July 2014 to December 2018. Hearing evaluation of 55 children diagnosed with CH was performed with a battery of tools that included Middle ear analysis, Pure Tone Audiometry (PTA), Behavioral Observation Audiometry (BOA) and Oto Acoustic Emissions (OAE). The choice of assessment tool was based on patient’s age. Results: The mean age at diagnosis and at inclusion into the study was 2.0±1.7 years and 3.2±2.3 years respectively. The etiological diagnosis was thyroid agenesis in 40(72.7%), ectopia in 3(5.5%), dyshormonogenesis in 7(12.7%) and hypothyroidism with eutopic gland in 5(9.1%%) patients. Middle ear analysis, PTA, BOA and OAE was done in 35, 28, 32 and 37 patients respectively. Sensorineural hearing loss was detected in 1 out of 55(1.8%) patients while conductive hearing loss was found in 3(5.4%) patients. Conclusion: Hearing loss was present in a small proportion of patients with permanent CH. Further larger studies are required to determine the exact prevalence of hearing impairment in Bangladeshi children with CH. DS (Child) H J 2020; 36(1) : 14-19

scholarly journals A KCNQ4 c.546C>G Genetic Variant Associated with Late Onset Non-Syndromic Hearing Loss in a Taiwanese Population

Genes ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 1711
Author(s):  
Ting-Ting Yen ◽  
I-Chieh Chen ◽  
Men-Wei Hua ◽  
Chia-Yi Wei ◽  
Kai-Hsiang Shih ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Late Onset ◽  
Clinical Manifestations ◽  
Pure Tone Audiometry ◽  
The Elderly ◽  
High Frequency Hearing Loss ◽  
Increased Risk ◽  
Syndromic Hearing Loss ◽  
Precision Medicine Initiative

Clinical presentation is heterogeneous for autosomal dominant nonsyndromic hearing loss (ADNSHL). Variants of KCNQ4 gene is a common genetic factor of ADNSHL. Few studies have investigated the association between hearing impairment and the variant c.546C>G of KCNQ4. Here, we investigated the phenotype and clinical manifestations of the KCNQ4 variant. Study subjects were selected from the participants of the Taiwan Precision Medicine Initiative. In total, we enrolled 12 individuals with KCNQ4 c.546C>G carriers and 107 non-carriers, and performed pure tone audiometry (PTA) test and phenome-wide association (PheWAS) analysis for the patients. We found that c.546C>G variant was related to an increased risk of hearing loss. All patients with c.546C>G variant were aged >65 years and had sensorineural and high frequency hearing loss. Of these patients, a third (66.7%) showed moderate and progressive hearing loss, 41.7% complained of tinnitus and 16.7% complained of vertigo. Additionally, we found a significant association between KCNQ4 c.546C>G variant, aortic aneurysm, fracture of lower limb and polyneuropathy in diabetes. KCNQ4 c.546C>G is likely a potentially pathogenic variant of ADNSHL in the elderly population. Genetic counseling, annual audiogram and early assistive listening device intervention are highly recommended to prevent profound hearing impairment in this patient group.

scholarly journals Survey of hearing disorders in an urban population in Rondonia, Northern Brazil

2013 ◽  
Vol 47 (2) ◽  
pp. 309-315 ◽  
Author(s):  
Maria Cecilia Bevilacqua ◽  
Marcos Roberto Banhara ◽  
Ariadnes Nobrega de Oliveira ◽  
Adriane Lima Mortari Moret ◽  
Katia de Freitas Alvarenga ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Urban Area ◽  
Pure Tone Audiometry ◽  
Household Survey ◽  
World Health ◽  
Hearing Disorders ◽  
Cross Sectional ◽  
Northern Brazil ◽  
Health Organization

OBJECTIVE: To identify the prevalence of hearing loss for the population in the urban area. METHODS: A cross-sectional household survey based on the World Health Organization Ear and Hearing Disorders Survey Protocol was conducted in 298 households in the urban area of Monte Negro, Rondonia, Northern Brazil, from 2005 to 2007. Ear examinations, behavioral audiometry and pure tone audiometry were conducted on 577 individuals. RESULTS: The results showed that 3.8% (95%CI 2.17;5.45) of population were classified in the disabling hearing impairment category. The prevalence of moderate hearing impairment was 3.4%; severe impairment was 0.4%; and profound hearing impairment was not found. CONCLUSIONS: The impairing hearing loss prevalence found in this study is within of the international prevalence for this level of hearing loss and smaller than observed in a previous study in the South region of Brazil.

Frequency of hearing impairment in children between the age of 2 to 10 years with middle ear infection

2021 ◽  
pp. 1-10
Author(s):  
Sultan Badar Munir ◽  
Imran Saeed ◽  
Sikander Ghayas Khan ◽  
Syed Shakeel Ur Rehman ◽  
Rabia Ghayas ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Middle Ear ◽  
Sampling Technique ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Ear Infection ◽  
Middle Ear Infection ◽  
Ear Infections ◽  
Convenience Sampling

Abstract This study was conducted to find out frequency of hearing impairment in middle ear infection. The study design was a cross- sectional survey, conducted from August 2018 to January 2019 in the ENT Department of Children's Hospital Lahore. The data was collected through convenience sampling technique among 52 patients of middle ear infection. The measurements for level of hearing impairment were taken. The data was analyzed using statistical package for social sciences, SPSS 20.0 Out of total 52, There were found 15 (28.8%) had once a month ear infection and 37 (71.2%) had off and 35 (67.3%) patients had mild hearing, 13 (25%) had moderate, 2(3.8%) severe and 2 (3.8%) had normal hearing loss. It was concluded that most of the participants having middle ear infections had hearing loss. Keywords: Hearing Impairment, Middle Ear Infection, Continuous...

Impedance Audiometry Suggested

PEDIATRICS ◽  
1974 ◽  
Vol 54 (3) ◽  
pp. 384-384
Author(s):  
John A. McCurdy
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Otitis Media ◽  
Middle Ear ◽  
Verbal Ability ◽  
Secretory Otitis Media ◽  
Suppurative Otitis Media ◽  
Significant Percentage ◽  
Children With Hearing Loss ◽  
Verbal Development

The findings of Kaplan et al.1 with respect to impairment of verbal ability in Alaskan children with hearing loss greater than 25 dB ISO secondary to chronic suppurative otitis media warrant renewed attention to a similar otologic problem which constitutes a threat to the verbal development of a significant percentage of all children—hearing impairment secondary to chronic secretory otitis media. Although the hearing loss in chronic secretory otitis media may fluctuate, a significant conductive impairment will persist as long as fluid remains in the middle ear.

Clinical Asssessment of Sensorineural Hearing Loss among Diabetes Mellitus Patients

2020 ◽  
Vol 28 (2) ◽  
pp. 112-119
Author(s):  
Raveendra P Gadag ◽  
Puneeth S Nayak ◽  
Tejaswini J
Keyword(s):  
Hearing Loss ◽  
Blood Glucose ◽  
Family History ◽  
Hearing Impairment ◽  
Fasting Blood Glucose ◽  
Bone Conduction ◽  
Pure Tone Audiometry ◽  
Chi Square ◽  
History Of ◽  
And Gender

Background: Hearing impairment is known to hamper the quality of life among patients, especially among diabetics due to the association of neuropathy with diabetes. However, the prevalence and degree of the SNHL depends upon different factors, such as age, gender, disease duration of DM, family history and glycemic status of the patients. Therefore, this study aimed to assess the association of SNHL with DM duration and familial DM and gender preponderance among SNHL–DM patients. Methods: Total 140 patients with DM were assessed for hearing impairment using Rinne, Weber and Absolute Bone Conduction Tests along with pure tone audiometry. Patients’ glycaemic status was determined by estimating fasting blood glucose (FBG) and post prandial blood glucose (PPBG) levels. Independent t-test, chi-square, ANOVA and Pearson’s correlation tests along with linear regression model were used to find association and correlation using R software. Results: Out of 140 patients, 60 were suffering from SNHL and majority were suffering from bilateral minimal hearing loss. SNHL was significantly associated with family history, age, duration of DM, FBG and PPBG levels were(Pvalues:1.79E08, 4.41E-06 and 0.02), however, significant correlated with duration of DM, FBS and PPBG level (r value:0.14–0.41).Furthermore, significant SNHL at 500 and 8000Hz was observed in the present study (Pvalue:0.002). Conclusion: A conclusive proof was drawn that family history of DM serve as a valuable variable in assessing the SNHL among DM patients.

Quality of life measures in otitis media

2013 ◽  
Vol 127 (5) ◽  
pp. 442-447 ◽  
Author(s):  
E J Maile ◽  
R Youngs
Keyword(s):  
Quality Of Life ◽  
Hearing Loss ◽  
Hearing Impairment ◽  
Otitis Media ◽  
Chronic Otitis Media ◽  
Pure Tone Audiometry ◽  
Quality Of Life Measures ◽  
Generic Measures ◽  
Disease Specific

AbstractDisabling hearing impairment is the world's most common disability. Traditionally, hearing levels measured by pure tone audiometry have been used to define and quantify hearing loss. The effects of disabling hearing loss on patients' quality of life can be profound, and audiometric data alone may not correlate with quality of life measures. Generic measures of quality of life can be used to compare different diseases, and as such are useful in resource allocation and burden of disease studies. Their disadvantage is that they are not disease-specific and can therefore under-estimate the effects of a disease on patients' quality of life. Disease-specific measures are more sensitive. In chronic otitis media, additional factors such as discharge augment the effect of hearing loss alone on quality of life. Many of the quality of life measures developed for chronic otitis media have been used to assess improvement following reconstructive surgery. Quality of life measures have also been used to assess the effect of paediatric otitis media. Quality of life measures also have utility in the developing world, where hearing impairment is a huge burden.

scholarly journals Hearing Characteristics of Stroke Patients: Prevalence and Characteristics of Hearing Impairment and Auditory Processing Disorders in Stroke Patients

2017 ◽  
Vol 28 (06) ◽  
pp. 491-505 ◽  
Author(s):  
Nehzat Koohi ◽  
Deborah A. Vickers ◽  
Rahul Lakshmanan ◽  
Hoskote Chandrashekar ◽  
David J. Werring ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Auditory Processing ◽  
Otoacoustic Emissions ◽  
Pure Tone Audiometry ◽  
Stroke Survivors ◽  
Central Auditory Processing ◽  
Hearing Impairments ◽  
Stroke Patients ◽  
Brainstem Response

Background: Stroke survivors may suffer from a range of hearing impairments that may restrict their participation in postacute rehabilitation programs. Hearing impairment may have a significant impact on listening, linguistic skills, and overall communication of the affected stroke patient. However, no studies sought to systematically characterize auditory function of stroke patients in detail, to establish the different types of hearing impairments in this cohort of patients. Such information would be clinically useful in understanding and addressing the hearing needs of stroke survivors. Purpose: The present study aimed to characterize and classify the hearing impairments, using a detailed audiological assessment test battery, in order to determine the level of clinical need and inform appropriate rehabilitation for this patient population. Research Design: A case–control study. Study Sample: Forty-two recruited stroke patients who were discharged from a stroke unit and 40 control participants matched for age. Data Collection and Analysis: All participants underwent pure-tone audiometry and immittance measurements including acoustic reflex threshold, transient-evoked otoacoustic emissions, auditory-evoked brainstem response, and a central auditory processing assessment battery, performed in a single session. Hearing impairments were classified as peripheral hearing loss (cochlear and neural type), central auditory processing disorder (CAPD), and as a combination of CAPD and peripheral hearing loss. Results: Overall mean hearing thresholds were not significantly different between the control and stroke groups. The most common type of hearing impairment in stroke patients was the combination type, “peripheral and CAPD,” in the 61- to 80-yr-old subgroup (in 55%), and auditory processing deficits in 18- to 60-yr-olds (in 40%), which were both significantly higher than in controls. Conclusions: This is the first study to examine hearing function in detail in stroke patients. Given the importance of hearing for the efficiency of communication, it is essential to identify hearing impairments and differentiate peripheral and central deficits to define an appropriate intervention plan.

Hearing impairment among workers occupationally exposed to excessive levels of noise

Open Medicine ◽  
2007 ◽  
Vol 2 (3) ◽  
pp. 313-318 ◽  
Author(s):  
Pavlina Gidikova ◽  
Gospodinka Prakova ◽  
Petar Ruev ◽  
Gergana Sandeva
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Otoacoustic Emissions ◽  
Gradual Increase ◽  
Pure Tone Audiometry ◽  
Noise Levels ◽  
Distortion Products ◽  
Occupationally Exposed ◽  
Intermittent Noise ◽  
Excessive Noise

AbstractPure tone audiometry screening and ear examinations were conducted among 138 males working as machine and equipment operators occupationally exposed to intermittent noise of 85 to 105 dBA. Hearing loss up to 30 dB (preserved socially adequate hearing) was found in 25 workers. The hearing impairment was confirmed by distortion products of otoacoustic emissions measurements. A sharp increase in the frequency of cases can be found among the workers with service length over 10 years. While the frequency of the cases among workers with service length below 10 years is 5.45%, it is 26.5% among the subjects with service length over 10 years, with a gradual increase as a result of the increase in exposure duration. A positive correlation (p < 0.05) was found between the frequency of hearing impairment among the workers and the years of exposure to excessive noise levels. Some measures for preventing occupational noise-induced hearing loss were suggested.

scholarly journals Η συμβολή των ωτοακουστικών εκπομπών στη μελέτη της κοχλιακής λειτουργίας σε ασθενείς με υποθυρεοειδισμό

2013 ◽  
Author(s):  
Βασίλειος Ψαλτάκος
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Otoacoustic Emissions ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Otoacoustic Emission ◽  
Upper Respiratory Tract ◽  
Anatomic Site ◽  
Cochlear Function ◽  
Hearing Thresholds

Although several reports exist concerning the occurrence of hearing loss in patients withdisorders of thyroid function, there are still several unsettled issues, such as theincidence and the severity of hearing impairment, the anatomic site of the auditorypathway involved, and the possible pathogenetic mechanisms. Both congenitalhypothyroidism and environmentally based iodine deficiency are established causes ofhearing loss in humans and rodents. Congenital thyroid deficiency in humans can resultin a profound, hearing deficit, which may be prevented by early hormonal replacementtreatment in infants with hypothyroidism. However, the effect of acute or chronichypothyroidism in adults has not been adequately studied, and most information hasbeen obtained from animal experiments, whereas research in humans has been basicallybased on behavioral audiometry. The use of otoacoustic emissions may provide moreinsight into the hearing function of these patients than pure-tone audiometry, since it isconsidered as a sensitive test of the cochlear status. The aim of this study was toevaluate the hearing in a group of patients with acute hypothyroidism, using bothconventional audiometry and transiently evoked otoacoustic emissions (TEOAEs). Material and methods:A group of 52 patients with thyroid carcinoma who underwent total thyroidectomy wasstudied prospectively, All patients were examined before surgery and 6-8 weekspostoperatively. During this period there was no replacement with levothyroxine and themagnitude of thyroxin depletion was monitored by serum thyroid-stimulating hormone levels. On preoperative encounter with each patient, a detailed questionnaire of historyof hearing loss, tinnitus, vertigo, previous ear infections, noise exposure, medications,and recent upper respiratory tract infection was completed. Patients were excluded ifthey were older than 50 years, in order to avoid the phenomenon of presbycusis, or ifthey had a history of cochleovestibular, vascular or neurologic disease, or any other riskfactor for hearing impairment. Pure-tone audiometry, tympanometry and transientlyevoked otoacoustic emissions were performed. A group of healthy volunteers of similarage and sex were used for comparison.Results:(1) Tympanograms were normal, either on initial testing (75%) or on repeat testing(25%).(2) Audiometry showed elevation of all postoperative hearing thresholds, whereas thethresholds varied significantly across frequency.(3) TEOAE testing showed response signal to noise ratios lower in the postoperativesession (hypothyroid state) than in the preoperative session on all measured frequencies.(4) Emission levels varied significantly across frequency, with maximum responseobserved at 2 kHz.(5) Comparison of significant pure-tone and otoacoustic emission shifts for individualears showed more ears affected in otoacoustic emission testing, indicating subclinicalcochlear involvement.(6) Comparison of hearing thresholds and otoacoustic emission levels between patientsand controls showed significant differences on postoperative testing. Conclusions:Acute hypothyroidism in adults causes elevation of hearing thresholds and reducedotoacoustic emissions. The effect on otoacoustic emissions is greater, indicatingsubclinical damage of the cochlear function.

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