scholarly journals A study on blood flow in uterine artery, umbilical artery and middle cerebral artery using Doppler ultrasound in a group of patients with pregnancy induced hypertension

2021 ◽  
Vol 4 (2) ◽  
pp. 05-07
Author(s):  
Dr. Revanesh Navlaspur ◽  
Dr. Narendra GS
Keyword(s):  
Blood Flow ◽  
Middle Cerebral Artery ◽  
Doppler Ultrasound ◽  
Cerebral Artery ◽  
Uterine Artery ◽  
Umbilical Artery ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension

scholarly journals The Effect of Pregnancy-Induced Hypertension on Uteroplacental Vasculature Hemodynamic Changes and Pregnancy Outcome

2021 ◽  
pp. 211-215
Author(s):  
Fahmida Gul ◽  
Sameena Gul Memon ◽  
Maria Javaid ◽  
Suresh Kumar ◽  
Yaswant Rai ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Umbilical Artery ◽  
Color Doppler ◽  
Tertiary Care ◽  
Fetal Outcome ◽  
Care Hospital ◽  
Pregnancy Induced Hypertension ◽  
Uterine Arteries ◽  
Induced Hypertension

Background: Among the various complications of pregnancy, pregnancy-induced hypertension is found to be the most common which may affect maternal and fetal outcome. Pregnancy induced hypertension can cause growth retardation of fetus. Aim and Objective: This study aims to assess hemodynamic variations in uteroplacental circulation in pregnancy-induced hypertension and its effect on fetal outcome. Materials and Methods: The study was carried out at tertiary care hospital of nawab shah for the period of 06 months at Department of Radiology in association with Department of Gyne and Obs. Total 106 participants were selected for the study and all females were pregnant with 1st or 2nd trimester gestational record and medical history was taken from all participants and co-morbidities was also evaluated. Blood pressure was checked from all participants from their right arm in lying position and Ultrasound test was repeated as per requirement through color Doppler ultrasound machine and Data was analyzed by using statistical software SPSS. 24.00 version. Results: After collection of research data from all participants, the entire data was assembled for the analysis. Participants were divided into various age groups as 26 were in 18-21yeras, 34 in 22-25years, 21 in 26-29years and only 07 were from 34-37years. 26 participants were belongs to 1st trimester, 34 among 2nd trimester and 21 in third trimester. PI was also noted with three different readings 32 in Umbilical artery, 21 in middle cerebral artery and 37 in uterine artery. RI was also noted among different arteries 41 in umbilical, 36 in middle cerebral and 39 in uterine arteries. S/D was also noted, 33 in umbilical artery, 49 in middle cerebral artery and 30 in uterine arteries. Conclusion: Pregnancy-induced hypertension causes hemodynamic variations in uteroplacental vasculature which may be responsible for causing impaired fetal growth in some cases.

scholarly journals The Effect of Methyl Dopa, Nifedipine and Labetalol Treatment on Uterine, Umbilical and Fetal Middle Cerebral Artery Blood Flows in Cases Suffered from Pregnancy Induced Hypertension

2021 ◽  
pp. 84-94
Author(s):  
Menna Allah Kamal Hassan ◽  
Mohamed Mohsen Elnamory ◽  
Ayman Abd Elaziz Eldorf ◽  
Hesham Mohamed Eltokhy
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Pregnancy Induced Hypertension ◽  
Blood Flows ◽  
Methyl Dopa ◽  
Group I ◽  
Induced Hypertension ◽  
Doppler Indices

Background: Treatment of severe maternal hypertension is strongly indicated for the prevention of maternal complications, such as cerebrovascular accidents and placental abruption, for avoiding extreme pre maturity. The selection criteria for the various antihypertensive drugs are somewhat unclear, and although vasodilator agents reducing peripheral vascular resistance (e.g., methyldopa, nifidipine and labetalol) have been accepted for general obstetric use. The aim of the study is to compare the effect of methyl dopa, nifedipine and labetalol treatment on the doppler indices of uterine, umbilical and fetal middle cerebral artery blood flows in cases suffered from pregnancy induced hypertension. Methods: This prospective randomized comparative clinical trial study was carried out on 75 pregnant women suffered from pregnancy-induced hypertension. The patients were divided into three equal groups: Group I: received alpha methyldopa750 mg-2000 mg per day, Group II: received labetalol 100 mg twice per day and Group III: received nifedipine oral sustained tablets 20-120mg per day. Results: Follow up of the patients was done with assessment of the outcome measures and statistical analysis was done and revealed that the use of alpha methyldopa, nifedipine and labatalol in pregnancy induced hypertension cases produce significant reduction of blood pressure ,prolong pregnancy duration, decrease the need for maternal admission to the ICU due to uncontrolled severe hypertension, decrease insignificantly the progression of mild preeclampsia to severe preeclampsia without producing negative effect on the mother or the fetus because these drugs did not impair the uteroplacental or middle cerebral blood flow  documented by Doppler studies. Conclusions: Use of methyl dopa, nifidipine and labetalol treatment in PIH cases make an improvement of uteroplacental and middle cerebral blood flow which indicated by maternal uterine, umbilical and fetal middle cerebral arteries doppler indices (resistive index, pulatility index and S/D ratio). Labetalol is ideal first line of treatment because it has potent and fast hypotensive effect without producing significant side effects on the mother or fetus.

scholarly journals Doppler ultrasound in pregnancy – quality requirements of DEGUM and clinical application (part 2)

2021 ◽  
Author(s):  
Renaldo Faber ◽  
Kai-Sven Heling ◽  
Horst Steiner ◽  
Ulrich Gembruch
Keyword(s):  
Blood Flow ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Umbilical Artery ◽  
Prophylactic Treatment ◽  
Doppler Sonography ◽  
First Trimester ◽  
Ductus Venosus ◽  
Fetal Diagnosis

AbstractThis second part on Doppler sonography in prenatal medicine and obstetrics reviews its clinical applications. While this has not become the initially anticipated screening tool, it is used for the diagnosis and surveillance of a variety of fetal pathologies. For example, the sonography-based determination of uterine artery blood flow indices is an important parameter for the first trimester multimodal preeclampsia risk assessment, increasing accuracy and providing indication for the prophylactic treatment with aspirin. It also has significant implications for the diagnosis and surveillance of growth-restricted fetuses in the second and third trimesters through Doppler-sonographic analysis of umbilical artery, middle cerebral artery and ductus venosus. Here, especially the hemodynamics of the ductus venosus provides a critical criterium for birth management of severe, early-onset FGR before 34 + 0 weeks of gestation. Further, determination of maximum blood flow velocity of the middle cerebral artery is a central parameter in fetal diagnosis of anemia which has been significantly improved by this analysis. However, it is important to note that the mentioned improvements can only be achieved through highest methodological quality. Importantly, all these analyses are also applied to twins and higher order multiples. Here, for the differential diagnosis of specific complications such as TTTS, TAPS and TRAP, the application of Doppler sonography has become indispensable. To conclude, the successful application of Doppler sonography requires both exact methodology and precise pathophysiological interpretation of the data.

scholarly journals Significance of obstetric Doppler studies in prediction of perinatal outcome in pregnancy induced hypertension

2017 ◽  
Vol 6 (6) ◽  
pp. 2354 ◽  
Author(s):  
Pradip R. Gaikwad ◽  
Manisha R. Gandhewar ◽  
Nity Rose ◽  
Vidyadhar Suryakar
Keyword(s):  
Diagnostic Accuracy ◽  
Doppler Ultrasound ◽  
Predictive Value ◽  
Perinatal Outcome ◽  
Uterine Artery ◽  
Pregnancy Induced Hypertension ◽  
Doppler Studies ◽  
Uterine Artery Doppler ◽  
Adverse Perinatal Outcome ◽  
Induced Hypertension

Background: Pregnancy induced hypertension (PIH) is associated with adverse perinatal outcome. Multi vessel color Doppler studies are useful in these cases for timely intervention. The aim of present study was to know the significance of umbilical, middle cerebral and uterine artery Doppler studies in PIH and to analyse its role in predicting perinatal outcome.Methods: This was a prospective study of 106 singleton pregnancies in the third trimester with PIH. The results of last Doppler ultrasound within one week of delivery were used for analysis. Adverse perinatal outcome was studied in the form of emergency cesarean section for fetal distress, meconium stained amniotic fluid, Apgar at 5 min <7, NICU admission and perinatal mortality (stillbirths and neonatal death). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy of various Doppler parameters were calculated after comparing with standard.Results: In the present study specificity and diagnostic accuracy of all Doppler ultrasound parameters was high in predicting adverse perinatal outcome. Cerebroplacental ratio showed highest specificity (98.55%), PPV (94.44%) and diagnostic accuracy (80.19%) in predicting adverse perinatal outcome and it is better than MCA PI and UA PI alone. Uterine artery Doppler evaluation also gives additional information in predicting adverse perinatal outcome.Conclusions: Amongst various Doppler parameters cerebroplacental index (MCA/UA PI) is best predictor of adverse perinatal outcome.

“Check our watches”. III. Doppler ultrasonography in the second part of gestation

2018 ◽  
Author(s):  
M.V. Medvedev, N.A. Altynnik
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Uterine Artery ◽  
Doppler Ultrasonography ◽  
Umbilical Artery ◽  
Ductus Venosus

This article discusses issues of screening and comprehensive Doppler ultrasonography in the second part of gestation including assessment of the uterine artery, umbilical artery, fetal middle cerebral artery and ductus venosus waveforms.

The Effect of Antenatal Vaginal Progesterone Administration on Uterine, Umbilical, and Fetal Middle Cerebral Artery Doppler Flow: A Cohort Study

2019 ◽  
Vol 37 (05) ◽  
pp. 491-496
Author(s):  
Ahmed M. Maged ◽  
Amira Y. Shoab ◽  
Eman A. Hussein ◽  
Ahmed H. Alsawaf ◽  
Doaa S. Mahmoud ◽  
...  
Keyword(s):  
Cohort Study ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Uterine Artery ◽  
Umbilical Artery ◽  
Resistance Index ◽  
Doppler Measurement ◽  
Vaginal Progesterone ◽  
Before And After ◽  
Doppler Indices

Abstract Objective This study aimed to evaluate the effect of vaginal progesterone (P) administration during the second and third trimesters of pregnancy on Doppler velocimetry of uterine, umbilical, and middle cerebral vessels. Study Design A prospective cohort study conducted on 80 women at risk for preterm labor. Uterine artery, umbilical artery, and middle cerebral artery (MCA) Doppler indices were measured before and after 1 week of administration of 200 mg twice daily vaginal P. The primary outcome parameter was the change of MCA pulsatility index (PI) after P administration. Secondary outcomes included changes in uterine artery and umbilical artery Doppler measurement. Results There was no significant changes of umbilical artery resistance index (RI) (0.69 ± 0.049 vs. 0.68 ± 0.041), umbilical artery PI (1.14 ± 0.118 vs. 1.11 ± 0.116), uterine artery RI (0.66 ± 0.12 vs. 0.66 ± 0.107), uterine artery PI (1.00 ± 0.26 vs. 1.016 ± 0.24), and MCA PI (1.27 ± 0.18 vs. 1.26 ± 0.23) measurements before and after 1 week of P administration, respectively. Conclusion Administration of vaginal P has no significant effects on uterine artery, umbilical artery, and MCA Doppler indices.

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