scholarly journals Identifikasi Risiko dan Pencegahan Terhadap Nefropati Akibat Kontras

2016 ◽  
Vol 2 (1) ◽  
pp. 52-58
Author(s):  
Andre Tjie Wijaya ◽  
Budiawan Atmadja

The increase of application of iodinated contrast medium in diagnostic practice, combined with the increase of renal insufciency patients and elderly resulted in increasing incidency of contrast-induced nephropathy (CIN). The use of iodinated contrast medium need a careful assessment between risk and beneft, especially in patients with history of renal disease and elderly.  Assessment of renal function is based on glomerular fltration rate, not serum creatinine. Avoidance of iodinated contrast medium is the frst step to prevent the development of CIN. Consideration of alternative imaging is important. But, if iodinated contrast medium is needed, volume expansion intravenous before and after administration is the next acknowledged prevention step.

2019 ◽  
Vol 44 (1) ◽  
pp. 118-121 ◽  
Author(s):  
Honorio T Benzon ◽  
Jeffrey Schechtman ◽  
Sophy C Zheng ◽  
Jeffery A Katz ◽  
Arpan Patel ◽  
...  

In patients with a history of a hypersensitivity reaction to iodinated contrast medium, iodinated contrast medium is avoided, antihistamine and steroid premedication are given, or a gadolinium-based contrast agent is employed. Six patients with a history of a hypersensitivity reaction to iodinated contrast medium and who were not premedicated had an unintentional injection of iodinated contrast. None of the patients developed a moderate or severe reaction. All patients had gadopentetate dimeglumine in one of their injections; three had repeated injections of the gadopentetate. The lack of a significant reaction may be due to any or all of the following: questionable history of iodinated contrast reaction, low dose of iodinated contrast given, concomitant injection of (epidural) steroid, and slower absorption from epidural compared with intravenous injection. While it is reassuring to know that there is a low possibility of a moderate to severe reaction in these patients, every effort should be made to avoid this scenario, appropriate drugs and resuscitation equipment should be immediately available, and the patients should be observed adequately and followed for the possibility of late reactions. Recent publications have called for caution in the use of gadolinium-based contrast agents.


1995 ◽  
Vol 30 (12) ◽  
pp. 700-705 ◽  
Author(s):  
JOSEPH K.T LEE ◽  
DAVID M. WARSHAUER ◽  
WILLIAM H. BUSH ◽  
BRUCE L. McCLENNAN ◽  
PETER L. CHOYKE

Radiology ◽  
2009 ◽  
Vol 253 (3) ◽  
pp. 870-878 ◽  
Author(s):  
Douglas B. Macha ◽  
Rendon C. Nelson ◽  
Laurens E. Howle ◽  
John W. Hollingsworth ◽  
Sebastian T. Schindera

1974 ◽  
Vol 291 (1) ◽  
pp. 24-25 ◽  
Author(s):  
Manfred Blum ◽  
Uzi Weinberg ◽  
Louis Shenkman ◽  
Charles S. Hollander

2019 ◽  
Vol 8 (4) ◽  
pp. 283-288
Author(s):  
Tahere Zarouk Ahimahalle ◽  
Abdollah Amirfarhangi ◽  
Mosadegh Jabbari ◽  
Aria Jenabi ◽  
Hadia Bagherzadegan ◽  
...  

Introduction: Contrast-induced nephropathy (CIN) is one of the major causes of acute kidney injury. Objectives: Regarding an increase in mortality and morbidity in patients with CIN, this study aimed to evaluate the effect of oxygen therapy in prevention of the CIN in individuals with acute coronary syndrome undergoing emergent angiography. Patients and Methods: This study was a double-blinded clinical trial with control group (parallel design), randomized, and with a sample size of 204 individuals conducted on male or female patients over 35 years old and suspected of coronary artery disease undergoing emergent angiography refereed to Rasoul Akram hospital in 2018. Participants were divided into 2 groups (supplementary oxygen and oxygen-free groups). The first group received two to three liters of oxygen per minute from 10 minutes before the start of the procedure until the end of the procedure, and the second group inhaled the oxygen in the room air. Arterial blood gas (ABG) was taken prior to receiving oxygen and at the end of the procedure. Serum creatinine level was tested for all individuals before and 48 hours after the procedure. Results: The mean age in intervention and control groups was 61.66 ± 14.64 years and 60.49 ± 11.59 years, respectively (P=0.54). Mean glomerular filtration rate (GFR) and serum creatinine before and after angiography was not significantly different (P>0.05). There was a significant difference between the two genders regarding the development of CIN (P=0.002), which was higher in women from that of men. Female gender was a strong risk factor and approximately increased four times the risk of CIN (OR = 4.1; (P=0.001). History of chronic kidney disease (CKD) and hypertension (HTN) also produced such a situation (OR = 22.37; P=0.007). Conclusion: According to the results, oxygen therapy has no effect on the occurrence of CIN. It is also found that female gender, history of CKD and hypertension are risk factors for CIN.


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