scholarly journals Graphene-Based Flexible Sensors for Simultaneous Detection of Ascorbic Acid, Dopamine, and Uric Acid

Author(s):  
Shuaishuai Meng ◽  
Yaming Liu ◽  
Li Wang ◽  
Xixi Ji ◽  
Yun Chen ◽  
...  

Many diseases are closely related to abnormal concentrations of ascorbic acid (AA), dopamine (DA), and uric acid (UA). Therefore, the detection of these small molecules is significant for monitoring life metabolism and healthy states. Electrochemical detection has been widely used to detect small molecules due to its good selectivity, high sensitivity, and good economics. Fabrication and application are two sides of the coin, and we cannot give up one for the other. Graphene (GN) is a very suitable material for electrochemical sensing due to its excellent catalytic performance and large specific surface area. It possesses many excellent properties but cannot hold itself alone due to its nanoscale thickness. Herein, we have fabricated three-dimensional (3D) GN nanosheets (GNSs) on flexible carbon cloth (CC) by thermal chemical vapor deposition (CVD). The GNSs/CC can successfully detect AA, DA, and UA simultaneously. We find that these GNSs/CC sensors show good performance with 7 h CVD modification. The linear ranges of AA, DA, and UA are 0.02–0.1, 0.0005–0.02, and 0.0005–0.02 mM, respectively. The detection sensitivity rates of AA, DA, and UA are 5,470, 60,500, and 64,000 μA mM−1 cm−2, respectively. Our GNSs/CC flexible sensors can be successfully applied in the human serum for UA detection. The result matches with commercial sensors very well.

2021 ◽  
Vol 13 (38) ◽  
pp. 4503-4514
Author(s):  
Yasan He ◽  
Xiaogeng Lin ◽  
Yuan Tang ◽  
Ling Ye

Selective electrochemical sensing via H-bonding and electrostatic interactions.


2015 ◽  
Vol 7 (2) ◽  
pp. 779-786 ◽  
Author(s):  
S. Ramakrishnan ◽  
K. R. Pradeep ◽  
A. Raghul ◽  
R. Senthilkumar ◽  
Murali Rangarajan ◽  
...  

Platinum nanoparticle-decorated graphene and carbon nanotube (Pt-Gr-CNT) nanocomposites synthesized by a single step chemical vapor deposition process, serve as a promising platform for the simultaneous electrochemical sensing of dopamine, uric acid and ascorbic acid.


RSC Advances ◽  
2014 ◽  
Vol 4 (52) ◽  
pp. 27625 ◽  
Author(s):  
Haofan Sun ◽  
Jie Chao ◽  
Xiaolei Zuo ◽  
Shao Su ◽  
Xingfen Liu ◽  
...  

Nanomaterials ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 835 ◽  
Author(s):  
Zhaotian Cai ◽  
Yabing Ye ◽  
Xuan Wan ◽  
Jun Liu ◽  
Shihui Yang ◽  
...  

Various morphologies of iron oxide nanoparticles (Fe2O3 NPs), including cubic, thorhombic and discal shapes were synthesized by a facile meta-ion mediated hydrothermal route. To further improve the electrochemical sensing properties, discal Fe2O3 NPs with the highest electrocatalytic activity were coupled with graphene oxide (GO) nanosheets. The surface morphology, microstructures and electrochemical properties of the obtained Fe2O3 NPs and Fe2O3/GO nanohybrids were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) techniques. As expected, the electrochemical performances were found to be highly related to morphology. The discal Fe2O3 NPs coupled with GO showed remarkable electrocatalytic activity toward the oxidation of dopamine (DA) and uric acid (UA), due to their excellent synergistic effect. The electrochemical responses of both DA and UA were linear to their concentrations in the ranges of 0.02–10 μM and 10–100 μM, with very low limits of detection (LOD) of 3.2 nM and 2.5 nM for DA and UA, respectively. Moreover, the d-Fe2O3/GO nanohybrids showed good selectivity and reproducibility. The proposed d-Fe2O3/GO/GCE realized the simultaneous detection of DA and UA in human serum and urine samples with satisfactory recoveries.


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