scholarly journals Clocks, Rhythms, Sex, and Hearts: How Disrupted Circadian Rhythms, Time-of-Day, and Sex Influence Cardiovascular Health

Biomolecules ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 883
Author(s):  
O. Hecmarie Meléndez-Fernández ◽  
James C. Walton ◽  
A. Courtney DeVries ◽  
Randy J. Nelson
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Cardiovascular Diseases ◽  
Circadian Rhythms ◽  
Cardiovascular Health ◽  
Biological Rhythms ◽  
Cardiovascular Function ◽  
The United States ◽  
Time Of Day ◽  
And Behavior

Cardiovascular diseases are the top cause of mortality in the United States, and ischemic heart disease accounts for 16% of all deaths around the world. Modifiable risk factors such as diet and exercise have often been primary targets in addressing these conditions. However, mounting evidence suggests that environmental factors that disrupt physiological rhythms might contribute to the development of these diseases, as well as contribute to increasing other risk factors that are typically associated with cardiovascular disease. Exposure to light at night, transmeridian travel, and social jetlag disrupt endogenous circadian rhythms, which, in turn, alter carefully orchestrated bodily functioning, and elevate the risk of disease and injury. Research into how disrupted circadian rhythms affect physiology and behavior has begun to reveal the intricacies of how seemingly innocuous environmental and social factors have dramatic consequences on mammalian physiology and behavior. Despite the new focus on the importance of circadian rhythms, and how disrupted circadian rhythms contribute to cardiovascular diseases, many questions in this field remain unanswered. Further, neither time-of-day nor sex as a biological variable have been consistently and thoroughly taken into account in previous studies of circadian rhythm disruption and cardiovascular disease. In this review, we will first discuss biological rhythms and the master temporal regulator that controls these rhythms, focusing on the cardiovascular system, its rhythms, and the pathology associated with its disruption, while emphasizing the importance of the time-of-day as a variable that directly affects outcomes in controlled studies, and how temporal data will inform clinical practice and influence personalized medicine. Finally, we will discuss evidence supporting the existence of sex differences in cardiovascular function and outcomes following an injury, and highlight the need for consistent inclusion of both sexes in studies that aim to understand cardiovascular function and improve cardiovascular health.

scholarly journals Stroke and stroke risk factors as disease burden

2021 ◽  
pp. 146-151
Author(s):  
S. Ozturk ◽  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cardiovascular Diseases ◽  
Cardiovascular Health ◽  
Stroke Risk ◽  
Heart Diseases ◽  
Health Indicators ◽  
The United States ◽  
Blood Cholesterol ◽  
Stroke Risk Factor

Stroke is the most common cause of disability and death in the world. Cardiovascular disease rates increase with age (10.9 % for people aged 20–30 years and 85.3 % for people older than 80 years). Coronary heart diseases is the leading cause of deaths attributable to cardiovascular diseases in the United States, followed by stroke, high BP, HF, diseases of the arteries, and other cardiovascular diseases. The report on the global burden of neurological disorders has shown that hemorrhagic stroke accounted for 35.7 % in it, and ischemic stroke, 22.4 %. Seven indicators are important and strategic to prevent cardiovascular disorders; they include healthy diet, sufficient physical activity, smokingstatius, BMI, cholesterol level, blood pressure, and glucose in blood on a fasting stomach. These indicators are associated with healthy behavior (diet quality, PA, smoking, BMI) which are as important as health factors (blood cholesterol, BP, blood glucose). There is a strong protective association between ideal cardiovascular health indicators and many clinical and preclinical conditions including premature all-cause mortality, stroke, CVD mortality, ischemic heart disease mortality, HF, deep venous thromboembolism, and pulmonary embolism. Atrial fibrillation, metabolic syndrome, renal failure, and sleep apnea are important risk factors which are modifiable and treatable. Air pollution has been reported as an increasing and very important risk factor for stroke. COVID-19 has been reported as another new stroke risk factor during the pandemic. Future targets must include each cardiovascular health indicator to decrease stroke risk burden and stroke risk.

scholarly journals College Students’ Knowledge of Risk Factors Related to Cardiovascular Disease

2017 ◽  
Vol 2 (2) ◽  
pp. 11
Author(s):  
Christine Andrew ◽  
Deborah Hiles-Gaddy ◽  
Mikayla Lauren MacRitchie ◽  
Sam Abraham
Keyword(s):  
Risk Factors ◽  
College Students ◽  
Cardiovascular Disease ◽  
Fruits And Vegetables ◽  
Cardiovascular Health ◽  
The United States ◽  
Cross Sectional Study ◽  
Further Education ◽  
Dietary Sodium ◽  
Cross Sectional

Background: Cardiovascular disease (CVD) is a prevalent health issue, accounting for a large proportion of deaths worldwide. Despite the high prevalence of this potentially detrimental condition, many college students are not fully aware of its contributing risk factors. The purpose of the current study was to determine college students’ knowledge of risk factors related to CVD. Methods: This was a quantitative, cross-sectional study with a descriptive design. A survey with 5 demographic questions and 20 Likert-type statements was administered to 118 students in a Midwestern college in the United States. Results: The majority of the students displayed knowledge of risk factors such as smoking tobacco, inactive lifestyle, hypertension, low intake of fruits and vegetables, elevated cholesterol levels, high dietary sodium and obesity. However, a knowledge deficit existed regarding gender and ethnicity, which are non-modifiable risk factors, albeit important considerations.Conclusions: Although students appeared knowledgeable about areas such as cholesterol in cardiovascular health, further education could be beneficial to improve this knowledge base.

Cardiovascular Health among Asian Americans/Pacific Islanders: An Examination of Health Status and Intervention Approaches

1993 ◽  
Vol 7 (3) ◽  
pp. 199-207 ◽  
Author(s):  
Moon S. Chen
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Health Status ◽  
Asian Americans ◽  
Asian American ◽  
Cardiovascular Health ◽  
The United States ◽  
Pacific Islanders ◽  
Disease Mortality ◽  
Review Current

Purpose of the Review. The purpose of this review is to examine the cardiovascular health status of Asian Americans/Pacific Islanders by primary risk factor and review current intervention approaches targeting this population. Asian Americans/Pacific Islanders in the United States have experienced triple digit percentage increases in population for every decade since 1970. Despite their rapidly increasing numbers, little is known about their cardiovascular health status. Search Methods Used. This article reviews the literature on the demographics, mortality, and prevalence of major cadiovascular risk factors among Asian Americans/Pacific Islanders. Selected intervention programs are also described. Summary of Important Findings. Data on cardiovascular disease mortality for Asian Americans/Pacific Islanders are relatively limited because few states collect ethnically specific mortality statistics. Data on cardiovascular risk factors, particularly smoking and hypertension, for certain Asian American/Pacific Islander groups portend excessive cardiovascular disease burdens. Major Conclusions. Data specific to ethnic groups comprising Asian Americans and Pacific Islanders need to be culled. Also, scientifically valid and linguistically appropriate interventions approved by ethnic community leaders are needed to address Asian Americans/Pacific Islanders.

‘I think one of the ways they will help is to create awareness’: primary school teachers’ perceptions of cardiovascular diseases in Nigeria

2019 ◽  
Vol 27 (4) ◽  
pp. 24-31
Author(s):  
Kingsley Udeh ◽  
Candidus Nwakasi ◽  
John Fulton
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
Primary School ◽  
Cardiovascular Health ◽  
Communicable Diseases ◽  
Health Concern ◽  
Structured Interviews ◽  
School Teachers ◽  
Primary School Teachers ◽  
Non Communicable Diseases

The increasing incidence and prevalence of non-communicable diseases is a major global health concern. Cardiovascular diseases (CVDs) account for the highest percentage of deaths related to non-communicable diseases, and low and middle-income countries (LMIC) face the highest burden of CVDs. Understanding the knowledge and perception of CVDs and their risk factors in an LMIC such as Nigeria may play an important role in cardiovascular health promotion and improvement plans to reduce CVD-related deaths. A qualitative study was conducted using semi-structured interviews to gain an in-depth understanding of some personal and sociocultural views on CVDs and their risk factors. The participants were purposively sampled primary school teachers in South-Eastern Nigeria. Thematic analysis approach was used for data analysis. The study findings include knowledge of heart disease, perceived causes and risk factors of CVDs, spirituality, and the way forward. Overall, the knowledge of CVDs in the setting was found to be related to the psychosocial nature of the participants; the effectiveness of any intervention needs to take these factors into consideration. For example, health policies for CVD health education and awareness should be tailored to address some of the issues of belief, values, and religion, as mentioned in the study.

Cardiovascular Disease Risk Factors Among Immigrant and US-Born Adults in New York City

2021 ◽  
pp. 003335492110075
Author(s):  
Claudia Chernov ◽  
Lisa Wang ◽  
Lorna E. Thorpe ◽  
Nadia Islam ◽  
Amy Freeman ◽  
...  
Keyword(s):  
United States ◽  
Risk Factors ◽  
Cardiovascular Disease ◽  
New York ◽  
New York City ◽  
Health Insurance ◽  
York City ◽  
The United States ◽  
Nutrition Examination Survey ◽  
Health And Nutrition

Objectives Immigrant adults tend to have better health than native-born adults despite lower incomes, but the health advantage decreases with length of residence. To determine whether immigrant adults have a health advantage over US-born adults in New York City, we compared cardiovascular disease (CVD) risk factors among both groups. Methods Using data from the New York City Health and Nutrition Examination Survey 2013-2014, we assessed health insurance coverage, health behaviors, and health conditions, comparing adults ages ≥20 born in the 50 states or the District of Columbia (US-born) with adults born in a US territory or outside the United States (immigrants, following the National Health and Nutrition Examination Survey) and comparing US-born adults with (1) adults who immigrated recently (≤10 years) and (2) adults who immigrated earlier (>10 years). Results For immigrant adults, the mean time since arrival in the United States was 21.8 years. Immigrant adults were significantly more likely than US-born adults to lack health insurance (22% vs 12%), report fair or poor health (26% vs 17%), have hypertension (30% vs 23%), and have diabetes (20% vs 11%) but significantly less likely to smoke (18% vs 27%) (all P < .05). Comparable proportions of immigrant adults and US-born adults were overweight or obese (67% vs 63%) and reported CVD (both 7%). Immigrant adults who arrived recently were less likely than immigrant adults who arrived earlier to have diabetes or high cholesterol but did not differ overall from US-born adults. Conclusions Our findings may help guide prevention programs and policy efforts to ensure that immigrant adults remain healthy.

Prevention of atrial fibrillation – non-modifiable and modifiable risk factors for AF

2020 ◽  
Vol 2 (55) ◽  
pp. 14-19
Author(s):  
Agnieszka Wojdyła-Hordyńska ◽  
Grzegorz Hordyński
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Atrial Fibrillation ◽  
Cardiovascular Disease ◽  
Cardiovascular Diseases ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Combined Treatment ◽  
Lifestyle Changes ◽  
Modifiable Risk Factors

Atrial fibrillation is one of the most common arrhythmias, with a significant increase in incidence in recent years. AF is a major cause of stroke, heart failure, sudden cardiac death, and cardiovascular disease. Timely intervention and modification of risk factors increase chance to stop the disease. Aggressive, multilevel prevention tactics are a component of combined treatment, including – in addition to lifestyle changes, anticoagulant therapy, pharmacotherapy and invasive anti-arrhythmic treatment – prevention of cardiovascular diseases, hypertension, ischemia, valvular disease and heart failure.

Prevalence and Predictors of Cardiovascular Disease and Risk Factors in Transgender Persons in the United States

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Aditi Malhotra ◽  
Smadar Kort ◽  
Tara Lauther ◽  
Noelle Mann ◽  
Hal A. Skopicki ◽  
...  
Keyword(s):  
United States ◽  
Risk Factors ◽  
Cardiovascular Disease ◽  
The United States ◽  
Transgender Persons

scholarly journals UK Food Standards Agency α-linolenic acid workshop report

2002 ◽  
Vol 88 (5) ◽  
pp. 573-579 ◽  
Author(s):  
Peter Sanderson ◽  
Yvonne E. Finnegan ◽  
Christine M. Williams ◽  
Philip C. Calder ◽  
Graham C. Burdge ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Dietary Intake ◽  
Beneficial Effect ◽  
Linolenic Acid ◽  
Cardiovascular Health ◽  
Future Research ◽  
Chd Risk ◽  
Food Standards ◽  
Chd Risk Factors

The UK Food Standards Agency convened a group of expert scientists to review current research investigating whether n-3 polyunsaturated fatty acids (PUFA) from plant oils (α-linolenic acid; ALA) were as beneficial to cardiovascular health as the n-3 PUFA from the marine oils, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The workshop also aimed to establish priorities for future research. Dietary intake of ALA has been associated with a beneficial effect on CHD; however, the results from studies investigating the effects of ALA supplementation on CHD risk factors have proved equivocal. The studies presented as part of the present workshop suggested little, if any, benefit of ALA, relative to linoleic acid, on risk factors for cardiovascular disease; the effects observed with fish-oil supplementation were not replicated by ALA supplementation. There is a need, therefore, to first prove the efficacy of ALA supplementation on cardiovascular disease, before further investigating effects on cardiovascular risk factors. The workshop considered that a beneficial effect of ALA on the secondary prevention of CHD still needed to be established, and there was no reason to look further at existing CHD risk factors in relation to ALA supplementation. The workshop also highlighted the possibility of feeding livestock ALA-rich oils to provide a means of increasing the dietary intake in human consumers of EPA and DHA.

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