scholarly journals Morphological and Hemodynamic Changes during Cerebral Aneurysm Growth

2021 ◽  
Vol 11 (4) ◽  
pp. 520
Author(s):  
Emily R. Nordahl ◽  
Susheil Uthamaraj ◽  
Kendall D. Dennis ◽  
Alena Sejkorová ◽  
Aleš Hejčl ◽  
...  

Computational fluid dynamics (CFD) has grown as a tool to help understand the hemodynamic properties related to the rupture of cerebral aneurysms. Few of these studies deal specifically with aneurysm growth and most only use a single time instance within the aneurysm growth history. The present retrospective study investigated four patient-specific aneurysms, once at initial diagnosis and then at follow-up, to analyze hemodynamic and morphological changes. Aneurysm geometries were segmented via the medical image processing software Mimics. The geometries were meshed and a computational fluid dynamics (CFD) analysis was performed using ANSYS. Results showed that major geometry bulk growth occurred in areas of low wall shear stress (WSS). Wall shape remodeling near neck impingement regions occurred in areas with large gradients of WSS and oscillatory shear index. This study found that growth occurred in areas where low WSS was accompanied by high velocity gradients between the aneurysm wall and large swirling flow structures. A new finding was that all cases showed an increase in kinetic energy from the first time point to the second, and this change in kinetic energy seems correlated to the change in aneurysm volume.

Author(s):  
Fujimaro Ishida ◽  
Masanori Tsuji ◽  
Satoru Tanioka ◽  
Katsuhiro Tanaka ◽  
Shinichi Yoshimura ◽  
...  

AbstractHemodynamics is thought to play an important role in the pathogenesis of cerebral aneurysms and recent development of computer technology makes it possible to simulate blood flow using high-resolution 3D images within several hours. A lot of studies of computational fluid dynamics (CFD) for cerebral aneurysms were reported; therefore, application of CFD for cerebral aneurysms in clinical settings is reviewed in this article.CFD for cerebral aneurysms using a patient-specific geometry model was first reported in 2003 and it has been revealing that hemodynamics brings a certain contribution to understanding aneurysm pathology, including initiation, growth and rupture. Based on the knowledge of the state-of-the-art techniques, this review treats the decision-making process for using CFD in several clinical settings. We introduce our CFD procedure using digital imaging and communication in medicine (DICOM) datasets of 3D CT angiography or 3D rotational angiography. In addition, we review rupture status, hyperplastic remodeling of aneurysm wall, and recurrence of coiled aneurysms using the hemodynamic parameters such as wall shear stress (WSS), oscillatory shear index (OSI), aneurysmal inflow rate coefficient (AIRC), and residual flow volume (RFV).


2016 ◽  
Vol 819 ◽  
pp. 356-360
Author(s):  
Mazharul Islam ◽  
Jiří Fürst ◽  
David Wood ◽  
Farid Nasir Ani

In order to evaluate the performance of airfoils with computational fluid dynamics (CFD) tools, modelling of transitional region in the boundary layer is very critical. Currently, there are several classes of transition-based turbulence model which are based on different methods. Among these, the k-kL- ω, which is a three equation turbulence model, is one of the prominent ones which is based on the concept of laminar kinetic energy. This model is phenomenological and has several advantageous features. Over the years, different researchers have attempted to modify the original version which was proposed by Walter and Cokljat in 2008 to enrich the modelling capability. In this article, a modified form of k-kL-ω transitional turbulence model has been used with the help of OpenFOAM for an investigative CFD analysis of a NACA 4-digit airfoil at range of angles of attack.


2021 ◽  
Author(s):  
Chang Seop Kwon ◽  
Joo-Sung Kim ◽  
Hyun Joe Kim

Abstract A round bilge with a bilge keel structure is a key element which can alleviate roll motions of ships and floating structures by transferring the roll momentum of a floating body into the kinetic energy of water. This study presents a practical guide to properly designing a bilge radius and bilge keel height of a barge-shaped and tanker-shaped FPSOs. A parametric study to figure out the effect of bilge radius and bilge keel height on the roll damping performance is conducted through a series of numerical roll free decay simulations based on Computational Fluid Dynamics (CFD). The bilge radius is normalized by the half breadth of ship, and the bilge keel height is normalized by the maximum bilge keel height which is limited by the molded lines of a side shell and bottom shell. In addition, it is investigated to identify how the roll damping performance of a rectangular section differs from the result of a typical round bilge section with maximum available bilge keel height.


2005 ◽  
Vol os-14 (3) ◽  
pp. 1558925005os-14
Author(s):  
Eric M. Moore ◽  
Dimitrios V. Papavassiliou ◽  
Robert L. Shambaugh

An unconventional melt blowing die was analyzed using computational fluid dynamics (CFD). This die has an annular configuration wherein the jet inlet is tapered (the cross-sectional area decreases) as the air approaches the die face. It was found that the flow characteristics of this die are different from conventional slot and annular dies. In particular, for the tapered die the near-field normalized turbulent kinetic energy was found to be lower at shallow die angles. Also, it was found that the peak mean velocity behavior was intermediate between that of conventional annular and slot dies. The centerline turbulence profiles were found to be qualitatively similar to those of annular dies; quantitatively, higher values were present for tapered dies.


2012 ◽  
Vol 2012 ◽  
pp. 1-24 ◽  
Author(s):  
Jürgen Endres ◽  
Markus Kowarschik ◽  
Thomas Redel ◽  
Puneet Sharma ◽  
Viorel Mihalef ◽  
...  

Increasing interest is drawn on hemodynamic parameters for classifying the risk of rupture as well as treatment planning of cerebral aneurysms. A proposed method to obtain quantities such as wall shear stress, pressure, and blood flow velocity is to numerically simulate the blood flow using computational fluid dynamics (CFD) methods. For the validation of those calculated quantities, virtually generated angiograms, based on the CFD results, are increasingly used for a subsequent comparison with real, acquired angiograms. For the generation of virtual angiograms, several patient-specific parameters have to be incorporated to obtain virtual angiograms which match the acquired angiograms as best as possible. For this purpose, a workflow is presented and demonstrated involving multiple phantom and patient cases.


Sign in / Sign up

Export Citation Format

Share Document