scholarly journals Eucalyptol, an All-Purpose Product

Catalysts ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 48
Author(s):  
Joana F. Campos ◽  
Sabine Berteina-Raboin
Keyword(s):  
Organic Chemistry ◽  
Environmental Impact ◽  
Environmental Performance ◽  
Good Alternative ◽  
Optimization Process ◽  
Coupling Reactions ◽  
Green Solvents ◽  
Safety And Health ◽  
The Ideal

Eucalyptus plants have attracted the attention of researchers and environmentalists worldwide because they are a rapidly growing source of wood and a source of oil used for multiple purposes. The main and the most important oil component is 1,8-cineole (eucalyptol: 60%–85%). This review summarizes the literature reported to date involving the use of 1,8-cineole for the treatment of disorders. Additionally, we describe our efforts in the use of eucalyptol as a solvent for the synthesis of O,S,N-heterocycles. Solvents used in chemistry are a fundamental element of the environmental performance of processes in corporate and academic laboratories. Their influence on costs, safety and health cannot be neglected. Green solvents such as bio-based systems hold considerable additional promise to reduce the environmental impact of organic chemistry. The first section outlines the process leading to our discovery of an unprecedented solvent and its validation in the first coupling reactions. This section continues with the description of its properties and characteristics and its reuse as reported in the various studies conducted. The second section highlights the use of eucalyptol in a series of coupling reactions (i.e., Suzuki–Miyaura, Sonogashira–Hagihara, Buchwald–Hartwig, Migita–Kosugi–Stille, Hiyama and cyanation) that form O,S,N-heterocycles. We describe the optimization process applied to reach the ideal conditions. We also show that eucalyptol can be a good alternative to build heterocycles that contain oxygen, sulfur and nitrogen. These studies allowed us to demonstrate the viability and potential that bio solvents can have in synthesis laboratories.

scholarly journals Greener Synthesis of Nitrogen-Containing Heterocycles in Water, PEG, and Bio-Based Solvents

Catalysts ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 429
Author(s):  
Joana F. Campos ◽  
Sabine Berteina-Raboin
Keyword(s):  
Organic Chemistry ◽  
Environmental Performance ◽  
Ecological Impact ◽  
Nitrogen Heterocycles ◽  
Chemical Transformations ◽  
Pharmaceutical Drugs ◽  
Wide Scope ◽  
Green Solvents ◽  
Health Safety ◽  
Greener Synthesis

The solvents used in chemistry are a fundamental element of the environmental performance of processes in corporate and academic laboratories. Their influence on costs, health safety, and nature cannot be neglected. Quantitatively, solvents are the most abundant constituents of chemical transformations; therefore, acting on solvents and replacing standard solvents with safer products can have a great ecological impact. However, not all green solvents are suitable for the wide scope of organic chemistry reactions. A second point to consider is that 50% of pharmaceutical drugs are nitrogen heterocycles compounds. It therefore appeared important to provide an overview of the more ecological methodologies for synthesizing this class of compounds. In this review, all publications since 2000 that describe green reactions leading to the formation of nitrogen heterocycles using safe solvents were considered. We chose water, PEG, and bio-based solvents for their negligible toxicity. The synthesis of five-, six-, and seven-membered aromatic nitrogen heterocycles using green reactions reported in the literature to date is described.

Excellent environmental performance of beet sugar production in the Netherlands

2020 ◽  
pp. 161-165
Author(s):  
Bertram de Crom ◽  
Jasper Scholten ◽  
Janjoris van Diepen
Keyword(s):  
Climate Change ◽  
Land Use ◽  
Life Cycle ◽  
Environmental Impact ◽  
Water Consumption ◽  
Environmental Performance ◽  
Cane Sugar ◽  
Sugar Production ◽  
Beet Sugar ◽  
Glucose Syrup

To get more insight in the environmental performance of the Suiker Unie beet sugar, Blonk Consultants performed a comparative Life Cycle Assessment (LCA) study on beet sugar, cane sugar and glucose syrup. The system boundaries of the sugar life cycle are set from cradle to regional storage at the Dutch market. For this study 8 different scenarios were evaluated. The first scenario is the actual sugar production at Suiker Unie. Scenario 2 until 7 are different cane sugar scenarios (different countries of origin, surplus electricity production and pre-harvest burning of leaves are considered). Scenario 8 concerns the glucose syrup scenario. An important factor in the environmental impact of 1kg of sugar is the sugar yield per ha. Total sugar yield per ha differs from 9t/ha sugar for sugarcane to 15t/ha sugar for sugar beet (in 2017). Main conclusion is that the production of beet sugar at Suiker Unie has in general a lower impact on climate change, fine particulate matter, land use and water consumption, compared to cane sugar production (in Brazil and India) and glucose syrup. The impact of cane sugar production on climate change and water consumption is highly dependent on the country of origin, especially when land use change is taken into account. The environmental impact of sugar production is highly dependent on the co-production of bioenergy, both for beet and cane sugar.

Withdrawal Notice: Recent Advances in Sonogashira Cross-Coupling Reactions Under Solvent-Free Conditions

2020 ◽  
Vol 24 ◽  
Author(s):  
Teng Wang ◽  
Zongrui Liu ◽  
Songlin Wang ◽  
Esmail Vessally
Keyword(s):  
Organic Chemistry ◽  
Editorial Policy ◽  
Cross Coupling ◽  
Solvent Free ◽  
Coupling Reactions ◽  
Editorial Policies ◽  
Cross Coupling Reactions ◽  
Recent Advances ◽  
Solvent Free Conditions ◽  
Copyright Permission

The article has been withdrawn at the request of editor of the journal Current Organic Chemistry: Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused. The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php BENTHAM SCIENCE DISCLAIMER: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

scholarly journals A One-Pot Approach to Novel Pyridazine C-Nucleosides

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2341
Author(s):  
Flavio Cermola ◽  
Serena Vella ◽  
Marina DellaGreca ◽  
Angela Tuzi ◽  
Maria Rosaria Iesce
Keyword(s):  
Organic Chemistry ◽  
Research Field ◽  
Modified Nucleosides ◽  
Protecting Groups ◽  
Coupling Reactions ◽  
One Pot ◽  
Pharmacological Interest ◽  
Classical Methodology ◽  
Glycosyl Donor ◽  
Neutral Conditions

The synthesis of glycosides and modified nucleosides represents a wide research field in organic chemistry. The classical methodology is based on coupling reactions between a glycosyl donor and an acceptor. An alternative strategy for new C-nucleosides is used in this approach, which consists of modifying a pre-existent furyl aglycone. This approach is applied to obtain novel pyridazine C-nucleosides starting with 2- and 3-(ribofuranosyl)furans. It is based on singlet oxygen [4+2] cycloaddition followed by reduction and hydrazine cyclization under neutral conditions. The mild three-step one-pot procedure leads stereoselectively to novel pyridazine C-nucleosides of pharmacological interest. The use of acetyls as protecting groups provides an elegant direct route to a deprotected new pyridazine C-nucleoside.

scholarly journals Development of Building Information Modeling Template for Environmental Impact Assessment

2021 ◽  
Vol 13 (6) ◽  
pp. 3092
Author(s):  
Sungwoo Lee ◽  
Sungho Tae ◽  
Hyungjae Jang ◽  
Chang U. Chae ◽  
Youngjin Bok
Keyword(s):  
Environmental Impact ◽  
Performance Assessment ◽  
Environmental Performance ◽  
Building Materials ◽  
Building Information Modeling ◽  
Information Modeling ◽  
Assessment Tools ◽  
Building Information ◽  
Environmental Performance Assessment ◽  
Assessment Results

Eco-friendly building designs that use building information modeling (BIM) have become popular, and a variety of eco-friendly building assessment technologies that take advantage of BIM are being developed. However, existing building environmental performance assessment technologies that use BIM are linked to external assessment tools, and there exist compatibility issues among programs; it requires a considerable amount of time to address these problems, owing to the lack of experts who can operate the programs. This study aims to develop eco-friendly templates for assessing the embodied environmental impact of buildings using BIM authoring tools as part of the development of BIM-based building life cycle assessment (LCA) technologies. Therefore, an embodied environmental impact unit database was developed, for major building materials during production and operating stages, to perform embodied environmental impact assessments. Moreover, a major structural element library that uses the database was developed and a function was created to produce building environmental performance assessment results tables, making it possible to review the eco-friendliness of buildings. A case study analysis was performed to review the feasibility of the environmental performance assessment technologies. The results showed a less than 5% effective error rate in the assessment results that were obtained using the technology developed in this study compared with the assessment results based on the actual calculation and operating stage energy consumption figures, which proves the reliability of the proposed approach.

scholarly journals On the Use of Iron in Organic Chemistry

Molecules ◽  
2020 ◽  
Vol 25 (6) ◽  
pp. 1349 ◽  
Author(s):  
Arnar Guðmundsson ◽  
Jan-E. Bäckvall
Keyword(s):  
Organic Chemistry ◽  
Redox Potential ◽  
Potential Range ◽  
Coupling Reactions ◽  
Base Metals ◽  
Metal Catalysis ◽  
Iron Catalysis ◽  
Cross Coupling Reactions ◽  
Life On Earth ◽  
Palladium Platinum

Transition metal catalysis in modern organic synthesis has largely focused on noble transition metals like palladium, platinum and ruthenium. The toxicity and low abundance of these metals, however, has led to a rising focus on the development of the more sustainable base metals like iron, copper and nickel for use in catalysis. Iron is a particularly good candidate for this purpose due to its abundance, wide redox potential range, and the ease with which its properties can be tuned through the exploitation of its multiple oxidation states, electron spin states and redox potential. This is a fact made clear by all life on Earth, where iron is used as a cornerstone in the chemistry of living processes. In this mini review, we report on the general advancements in the field of iron catalysis in organic chemistry covering addition reactions, C-H activation, cross-coupling reactions, cycloadditions, isomerization and redox reactions.

scholarly journals What Is the Environmental Impact of Wine Entering Global Value Chains? Studying the Evolution of CO2 Emissions from the Export of Spanish Denomination of Origin Wines

Foods ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1664
Author(s):  
Juan Sebastián Castillo-Valero ◽  
Inmaculada Carrasco ◽  
Marcos Carchano ◽  
Carmen Córcoles
Keyword(s):  
Environmental Impact ◽  
Co2 Emissions ◽  
Carbon Footprint ◽  
Environmental Performance ◽  
Service Provision ◽  
International Markets ◽  
Value Chains ◽  
Input Output ◽  
Continuous Growth ◽  
Wine Trade

The continuous growth of the international wine trade and the expansion of international markets is having significant commercial, but also environmental, impacts. The benefits of vineyards in terms of ecosystem service provision are offset by the increase in CO2 emissions generated by transportation. Denominations of Origin, as quality labels, emphasise a wine’s links to the terroir, where specific elements of culture and environment merge together. However, Denominations of Origin can also have differentiating elements as regards environmental performance. Drawing on an extended multiregional input–output model applied to the Spanish Denominations of Origin with the largest presence in the international wine trade, this study shows that wines with the greatest exporting tradition are those that most reduced their carbon footprint per litre of exported wine in the period 2005–2018, thus being the most environmentally efficient.

scholarly journals Three eco-tool comparison with the example of the environmental performance of domestic solar flat plate hot water systems

2013 ◽  
Vol 9 (2) ◽  
pp. 174-181
Keyword(s):  
Environmental Impact ◽  
Environmental Performance ◽  
Life Cycle Analysis ◽  
Hot Water ◽  
International Standards ◽  
Huge Amount ◽  
Product Lca ◽  
Lca Practitioners ◽  
Standards And Guidelines

Life Cycle Analysis (LCA) is a procedure used as an analytical tool for the evaluation of the environmental impact caused by a material, a manufacturing process or product. For an end product, LCA requires both the identification and quantification of materials and energy used in all stages of the product’s life, together with their environmental impact. It requires therefore a huge amount of data about materials, components, manufacturing processes, energy consumption and the relevant environmental impacts. For this reason, a number of software and databases have been developed, in order to facilitate LCA users. These are the so-called Eco-Tools, used in an effort to minimize the environmental impact of a product from the materials and the energy used for production. In this paper, LCA is conducted for solar thermosyphonic systems, with the aid of three commercially available Eco-Tools, usually used by LCA practitioners, namely: Eco-It, GEMIS and SimaPro, and the results are compared. Although all three tools claim accordance with the international standards and guidelines, differences do exist. A typical solar thermosyphonic system (DSHWS) with a 4 m2 collector area and a capacity of 150 dm3 that covers the hot water needs of a three person family in Thessaloniki is used as case study. The results of the three tools are compared for each component of the solar system as well as for each material used and for the conventional energy substituted by the system.

scholarly journals Heterogeneous acidic catalysts for the tetrahydropyranylation of alcohols and phenols in green ethereal solvents

2018 ◽  
Vol 14 ◽  
pp. 1655-1659 ◽  
Author(s):  
Ugo Azzena ◽  
Massimo Carraro ◽  
Gloria Modugno ◽  
Luisa Pisano ◽  
Luigi Urtis
Keyword(s):  
Organic Chemistry ◽  
Heterogeneous Catalysis ◽  
Important Class ◽  
Green Solvents ◽  
Reaction Products ◽  
Reaction Conditions ◽  
One Pot ◽  
Acidic Catalysts ◽  
Set Up ◽  
Work Up

The application of heterogeneous catalysis and green solvents to the set up of widely employed reactions is a challenge in contemporary organic chemistry. We applied such an approach to the synthesis and further conversion of tetrahydropyranyl ethers, an important class of compounds widely employed in multistep syntheses. Several alcohols and phenols were almost quantitatively converted into the corresponding tetrahydropyranyl ethers in cyclopentyl methyl ether or 2-methyltetrahydrofuran employing NH4HSO4 supported on SiO2 as a recyclable acidic catalyst. Easy work up of the reaction mixtures and the versatility of the solvents allowed further conversion of the reaction products under one-pot reaction conditions.

The Improvement of Environmental Performance in the Nonprofit Sector Through Informatics

2011 ◽  
pp. 359-376
Author(s):  
Konstantinos G. Papaspyropoulos ◽  
Athanassios S. Christodoulou ◽  
Vaios Blioumis ◽  
Kyriakos E. Skordas ◽  
Periklis K. Birtsas
Keyword(s):  
Time Series ◽  
Environmental Impact ◽  
Environmental Performance ◽  
Negative Impact ◽  
Nonprofit Sector ◽  
Policy Decision ◽  
Cointegration Analysis ◽  
Environmental Data ◽  
Policy Decision Making ◽  
Negative Environmental Impact

The purpose of the present chapter is to demonstrate how an econometric application supported by the use of simple software can augment an environmental nonprofit organization’s (ENPO) environmental performance. An ENPO, whose scope of operation is the protection of natural resources, usually deals with the problem of how to reduce its negative environmental impact without sacrificing the positive one resulting from its work. This chapter argues that the application of cointegration analysis on available time series environmental data can offer an indication for the policy decision-making in terms of such a contrast in impacts. If the time series are not cointegrated, then the ENPO can reduce its negative environmental impact without affecting the positive one. If they are cointegrated, then alternative policies have to be designated for dealing with the negative impact.

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