Alkylation of carboxylic acids in a microfluidic device: kinetics parameters determination, Hammett reaction constant measurement and optimization of preparative experiment

2009 ◽  
Author(s):  
Christian Rolando ◽  
Maël Penhoat ◽  
Azarmidokht Gholamipour-Shirazi
Keyword(s):  
Carboxylic Acids ◽  
Microfluidic Device ◽  
Kinetics Parameters ◽  
Constant Measurement ◽  
Reaction Constant

A quantitative analysis of solvent effects on reaction constant

1980 ◽  
Vol 33 (6) ◽  
pp. 1175 ◽  
Author(s):  
B Poh
Keyword(s):  
Dielectric Constant ◽  
Hydrogen Bonding ◽  
Quantitative Analysis ◽  
Transition State ◽  
Organic Acids ◽  
Carboxylic Acids ◽  
Solvent Effects ◽  
Effective Dielectric Constant ◽  
Reaction Constant

Solvent effects on reaction constant ρ for the dissociation equilibria of several series of organic acids are analysed in terms of three factors, namely, (i) variation in the effective dielectric constant, (ii) variation in the hydrogen-bonding ability of solvents, and (iii) variation in the conformation of the acids. A fourth factor, variation in the charge developed in the transition state of the reaction, is included in the analysis of ρ for reactions between diazodiphenylmethane and several series of carboxylic acids. It is shown that the ρ values for the dissociation equilibria of series of acids in other solvents can be calculated from their ρ values in water.

A convenient preparative method for 1,4-diketones from carboxylic acids

1977 ◽  
Vol 27 (1) ◽  
pp. 117-120
Author(s):  
Shoji Watanabe ◽  
Tsutomu Fujita ◽  
Kyoichi Suga ◽  
Haruhiko Abe
Keyword(s):  
Carboxylic Acids ◽  
Preparative Method

Probing The Resolution of 2-Alkoxy and 2-Aryloxy Carboxylic Acids

2006 ◽  
Author(s):  
Jason Eames ◽  
Ewan Boyd ◽  
Sameer Chavda
Keyword(s):  
Carboxylic Acids

Novel Microfluidic Device Integrated with a Fluidic-Capacitor to Mimic Heart Beating for Generation of Functional Liver Organoids

2019 ◽  
Vol 139 (7) ◽  
pp. 209-216
Author(s):  
Jiaxu Wu ◽  
Yoshikazu Hirai ◽  
Ken-ichiro Kamei ◽  
Toshiyuki Tsuchiya ◽  
Osamu Tabata
Keyword(s):  
Microfluidic Device ◽  
Heart Beating ◽  
Liver Organoids

Pneumatically-driven Microfluidic Device for Evaluating Active Transport by Kinesin Motor Protein

2016 ◽  
Vol 136 (9) ◽  
pp. 384-389
Author(s):  
Kazuya Fujimoto ◽  
Hirofumi Shintaku ◽  
Hidetoshi Kotera ◽  
Ryuji Yokokawa
Keyword(s):  
Active Transport ◽  
Microfluidic Device ◽  
Motor Protein ◽  
Kinesin Motor

A microfluidic device with integrated impedance detection for λ-DNA

2003 ◽  
Vol 773 ◽  
Author(s):  
Myung-Il Park ◽  
Jonging Hong ◽  
Dae Sung Yoon ◽  
Chong-Ook Park ◽  
Geunbae Im
Keyword(s):  
Microfluidic Device ◽  
Electrochemical Impedance ◽  
Direct Detection ◽  
Full Potential ◽  
Label Free ◽  
Buffer Solution ◽  
Detection Systems ◽  
Significant Difference ◽  
Detection Of Biomolecules ◽  
Impedance Magnitude

AbstractThe large optical detection systems that are typically utilized at present may not be able to reach their full potential as portable analysis tools. Accurate, early, and fast diagnosis for many diseases requires the direct detection of biomolecules such as DNA, proteins, and cells. In this research, a glass microchip with integrated microelectrodes has been fabricated, and the performance of electrochemical impedance detection was investigated for the biomolecules. We have used label-free λ-DNA as a sample biomolecule. By changing the distance between microelectrodes, the significant difference between DW and the TE buffer solution is obtained from the impedance-frequency measurements. In addition, the comparison for the impedance magnitude of DW, the TE buffer, and λ-DNA at the same distance was analyzed.

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