scholarly journals Impact of Respiratory Fluctuation on Hemodynamics in Human Cardiovascular System: A 0-1D Multiscale Model

Fluids ◽  
2022 ◽  
Vol 7 (1) ◽  
pp. 28
Author(s):  
Ruichen Li ◽  
Koichi Sughimoto ◽  
Xiancheng Zhang ◽  
Sirui Wang ◽  
Yuto Hiraki ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Pressure Fluctuations ◽  
Intrathoracic Pressure ◽  
Multiscale Model ◽  
Hemodynamic Instability ◽  
Flow Rates ◽  
System A ◽  
Hemodynamic Model ◽  
Human Cardiovascular System ◽  
The Individual

To explore hemodynamic interaction between the human respiratory system (RS) and cardiovascular system (CVS), here we propose an integrated computational model to predict the CVS hemodynamics with consideration of the respiratory fluctuation (RF). A submodule of the intrathoracic pressure (ITP) adjustment is developed and incorporated in a 0-1D multiscale hemodynamic model of the CVS specified for infant, adolescent, and adult individuals. The model is verified to enable reasonable estimation of the blood pressure waveforms accounting for the RF-induced pressure fluctuations in comparison with clinical data. The results show that the negative ITP caused by respiration increases the blood flow rates in superior and inferior vena cavae; the deep breathing improves the venous return in adolescents but has less influence on infants. It is found that a marked reduction in ITP under pathological conditions can excessively increase the flow rates in cavae independent of the individual ages, which may cause the hemodynamic instability and hence increase the risk of heart failure. Our results indicate that the present 0-1D multiscale CVS model incorporated with the RF effect is capable of providing a useful and effective tool to explore the physiological and pathological mechanisms in association with cardiopulmonary interactions and their clinical applications.

scholarly journals Personalized Hemodynamic Modeling of the Human Cardiovascular System: A Reduced-Order Computing Model

2020 ◽  
Vol 67 (10) ◽  
pp. 2754-2764
Author(s):  
Xiangdong Zhang ◽  
Dan Wu ◽  
Fen Miao ◽  
Hao Liu ◽  
Ye Li
Keyword(s):  
Cardiovascular System ◽  
Reduced Order ◽  
Computing Model ◽  
System A ◽  
Human Cardiovascular System

Effects of Temperature Variation on the Human Cardiovascular System: A Systematic Review

2016 ◽  
pp. 73-87 ◽  
Author(s):  
André Luís Foroni Casas ◽  
Gabriella Mendes Dias Santos ◽  
Natalia Bíscaro Chiocheti ◽  
Mônica de Andrade
Keyword(s):  
Systematic Review ◽  
Cardiovascular System ◽  
Temperature Variation ◽  
System A ◽  
Human Cardiovascular System ◽  
Effects Of Temperature

Measurement for Individual Gas-Liquid Two-Phase Flow Rates Based on Stochastic Features of Differential Pressure Fluctuation

2007 ◽  
Author(s):  
Tomomi Uchiyama ◽  
Hirokazu Tominaga ◽  
Kiyoshi Minemura
Keyword(s):  
Two Phase Flow ◽  
Pressure Fluctuations ◽  
Vortex Generator ◽  
Measuring Method ◽  
Differential Pressure ◽  
Phase Flow ◽  
Two Phase ◽  
Flow Rates ◽  
Individual Phase ◽  
The Individual

This study proposes a measuring method for the individual phase flow rates of gas-liquid two-phase mixtures flowing through a pipe. First, the time-variations for pressure are measured at three points around a vortex generator mounted in the pipe under the known flow rates. Secondly, the stochastic features of the differential pressure fluctuations, such as the mean and the standard deviation, are calculated to construct a database relating the flow rates with the stochastic features. Consequently, if the differential pressure fluctuations are measured under unknown flow rates, the individual phase flow rates are successfully identified from the database. A neural network is employed for the identification. This study also applies the proposed method for the measurement of air-water two-phase flow and discusses the measured results.

scholarly journals Analytical modeling of the human cardiovascular system with real-time implementation using NI ELVIS-II

2018 ◽  
Vol 7 (3.3) ◽  
pp. 628
Author(s):  
Sisir Chettri ◽  
Akash Kumar Bhoi ◽  
Gyoo Soo Chae ◽  
Nilas Gurung ◽  
Ashis Sharma
Keyword(s):  
Cardiovascular System ◽  
Real Time ◽  
Human Body ◽  
Blood Circulation ◽  
Lumped Parameter Model ◽  
Blood Flows ◽  
System A ◽  
Lumped Parameter ◽  
Electrical Analogy ◽  
Human Cardiovascular System

Cardiovascular System, which consists of the heart, the systematic circulation and the pulmonary circulation is said to be the transport system for the human body. Modeling of cardiovascular system has become important for clinical researchers and for deeper understanding of blood circulation in the human body. This paper uses the lumped method which is also known as an electrical analogy for modeling and simulation of human cardiovascular system. A simplified complete lumped parameter model of the Human Cardiovascular System has been developed with real time implementation focusing mainly on blood flows. A resistor, an inductor and a capacitor are used to model every blood vessel, ventricles, atrium and set of all veins and capillaries. A pulse generating circuit is also modeled which acts as a power supply for the heart that controls the contraction of heart muscles.   

Bifurcation in a Simple Model of the Cardiovascular System

2000 ◽  
Vol 39 (02) ◽  
pp. 118-121 ◽  
Author(s):  
S. Akselrod ◽  
S. Eyal
Keyword(s):  
Nonlinear Dynamics ◽  
Blood Pressure ◽  
Heart Rate ◽  
Fixed Point ◽  
Cardiovascular System ◽  
Modified Model ◽  
Mayer Waves ◽  
Sustained Oscillations ◽  
Human Cardiovascular System ◽  
Physiological Values

Abstract:A simple nonlinear beat-to-beat model of the human cardiovascular system has been studied. The model, introduced by DeBoer et al. was a simplified linearized version. We present a modified model which allows to investigate the nonlinear dynamics of the cardiovascular system. We found that an increase in the -sympathetic gain, via a Hopf bifurcation, leads to sustained oscillations both in heart rate and blood pressure variables at about 0.1 Hz (Mayer waves). Similar oscillations were observed when increasing the -sympathetic gain or decreasing the vagal gain. Further changes of the gains, even beyond reasonable physiological values, did not reveal another bifurcation. The dynamics observed were thus either fixed point or limit cycle. Introducing respiration into the model showed entrainment between the respiration frequency and the Mayer waves.

scholarly journals Stabilizing interventional instruments in the cardiovascular system: A classification of mechanisms

2021 ◽  
Vol 89 ◽  
pp. 22-32
Author(s):  
Awaz Ali ◽  
Dimitra Dodou ◽  
Gerwin Smit ◽  
Ruben Rink ◽  
Paul Breedveld
Keyword(s):  
Cardiovascular System ◽  
System A

scholarly journals Weighing in on heart failure: the potential impact of bariatric surgery

2021 ◽  
Author(s):  
Tanuka Datta ◽  
Andrew J. Lee ◽  
Rachel Cain ◽  
Melissa McCarey ◽  
David J. Whellan
Keyword(s):  
Heart Failure ◽  
Bariatric Surgery ◽  
Weight Loss ◽  
Cardiovascular System ◽  
Economic Burden ◽  
Treatment Strategies ◽  
It Impacts ◽  
Potential Impact ◽  
The Individual ◽  
Physiologic System

AbstractObesity is a growing worldwide epidemic with significant economic burden that carries with it impacts on every physiologic system including the cardiovascular system. Specifically, the risk of heart failure has been shown to increase dramatically in obese individuals. The purpose of this review is to provide background on the individual burdens of heart failure and obesity, followed by exploring proposed physiologic mechanisms that interconnect these conditions, and furthermore introduce treatment strategies for weight loss focusing on bariatric surgery. Review of the existing literature on patients with obesity and heart failure who have undergone bariatric surgery is presented, compared, and contrasted.

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