scholarly journals Secondary Metabolites from Artemisia Genus as Biopesticides and Innovative Nano-Based Application Strategies

Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 3061
Author(s):  
Bianca Ivănescu ◽  
Ana Flavia Burlec ◽  
Florina Crivoi ◽  
Crăița Roșu ◽  
Andreia Corciovă
Keyword(s):  
Secondary Metabolites ◽  
Negative Impact ◽  
Crop Protection ◽  
Duration Of Action ◽  
Worldwide Distribution ◽  
Artemisia Species ◽  
Extended Duration ◽  
Reduced Toxicity ◽  
Available Information ◽  
Potential Use

The Artemisia genus includes a large number of species with worldwide distribution and diverse chemical composition. The secondary metabolites of Artemisia species have numerous applications in the health, cosmetics, and food sectors. Moreover, many compounds of this genus are known for their antimicrobial, insecticidal, parasiticidal, and phytotoxic properties, which recommend them as possible biological control agents against plant pests. This paper aims to evaluate the latest available information related to the pesticidal properties of Artemisia compounds and extracts and their potential use in crop protection. Another aspect discussed in this review is the use of nanotechnology as a valuable trend for obtaining pesticides. Nanoparticles, nanoemulsions, and nanocapsules represent a more efficient method of biopesticide delivery with increased stability and potency, reduced toxicity, and extended duration of action. Given the negative impact of synthetic pesticides on human health and on the environment, Artemisia-derived biopesticides and their nanoformulations emerge as promising ecofriendly alternatives to pest management.

Pharmacological Uses of the Plants Belonging to the Genus Commiphora

2020 ◽  
Vol 18 ◽  
Author(s):  
Subbiah Latha ◽  
Palanisamy Selvamani ◽  
Thangavelu Prabha
Keyword(s):  
Secondary Metabolites ◽  
Plant Species ◽  
Dna Cleavage ◽  
Structural Information ◽  
Chemical Constituents ◽  
Future Research ◽  
Pharmacological Properties ◽  
Chemical Structures ◽  
Indigenous Uses ◽  
Available Information

: Natural products have a unique place in the healthcare industry. The genus Commiphora emerged as a potential medicinal with huge benefits as evidenced through its use in various traditional and modern systems of medicine. Therefore, we aimed to prepare a concise review on the pharmacological activities and the indigenous uses of various plant species belonging to the genus Commiphora along with the structural information of various active botanical ingredients present in these plants based on the published literatures and scientific reports. To collect the various published literatures on Commiphora in various journals; to study and classify the available information on the pharmacological uses and chemical constituents; and to present the gathered information as a precise review to serve as a potential reference for future research. Pharmacological and phytochemical data on Commiphora plant species were collected from various journals, books, reference materials, websites including scientific databases, etc for compilation. This review article describes the various pharmacological properties of plants of Commiphora species viz., Anti-arthritic and anti-inflammatory, Anti-atherogenic, Antibacterial, Anti-coagulant, Anti-dicrocoeliasis, Anti-epileptic, Anti-fascioliasis, Anti-fungal, Anti-heterophyidiasis, Anti-hyper cholesterolemic, Anti-hyperlipidemic, Anti-hypothyroidism, Anti-obesity, Anti-osteoarthritic, Anti-osteoclastogenesis, Anti-oxidant, Anti-parasitic, Anti-pyretic, Anti-schistosomiasis, Anti-septic, Anti-thrombotic, Anti-ulcer, Cardioprotective, COX enzyme inhibitory, Cytotoxic /Anti-carcinogenic/Anti-cancer, DNA cleavage, Hypotensive, Inhibits lipid peroxidation, Inhibits NO and NO synthase production, Insecticidal, Local anesthetic, Molluscicidal, Smooth muscle relaxant, Tick repellent activities along with toxicity studies. Furthermore, the review also included various secondary metabolites isolated from various species of Commiphora genus along with their chemical structures serve as a ready resource for researchers. We conclude that the plant species belonging to the genus Commiphora possesses abundant pharmacological properties with a huge treasure of diverse secondary metabolites within themselves. This review indicates the necessity of further in-depth research, pre-clinical and clinical studies with Commiphora genus which may help to detect the unidentified potential of the Commiphora plant species.

scholarly journals Effect of UV Radiation and Salt Stress on the Accumulation of Economically Relevant Secondary Metabolites in Bell Pepper Plants

Agronomy ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 142 ◽  
Author(s):  
Jan Ellenberger ◽  
Nils Siefen ◽  
Priska Krefting ◽  
Jan-Bernd Schulze Lutum ◽  
Daniel Pfarr ◽  
...  
Keyword(s):  
Salt Stress ◽  
Secondary Metabolites ◽  
Negative Impact ◽  
Stress Conditions ◽  
Bell Pepper ◽  
Plant Performance ◽  
Production Cycle ◽  
Stress Effects ◽  
Leaf Level ◽  
Uv Stress

The green biomass of horticultural plants contains valuable secondary metabolites (SM), which can potentially be extracted and sold. When exposed to stress, plants accumulate higher amounts of these SMs, making the extraction and commercialization even more attractive. We evaluated the potential for accumulating the flavones cynaroside and graveobioside A in leaves of two bell pepper cultivars (Mavras and Stayer) when exposed to salt stress (100 mM NaCl), UVA/B excitation (UVA 4–5 W/m2; UVB 10–14 W/m2 for 3 h per day), or a combination of both stressors. Plant age during the trials was 32–48 days. HPLC analyses proved the enhanced accumulation of both metabolites under stress conditions. Cynaroside accumulation is effectively triggered by high-UV stress, whereas graveobioside A contents increase under salt stress. Highest contents of secondary metabolites were observed in plants exposed to combined stress. Effects of stress on overall plant performance differed significantly between treatments, with least negative impact on above ground biomass found for high-UV stressed plants. The usage of two non-destructive instruments (Dualex and Multiplex) allowed us to gain insights into the ontogenetical effects at the leaf level and temporal development of SM contents. Indices provided by those devices correlate fairly with amounts detected via HPLC (Cynaroside: r2 = 0.46–0.66; Graveobioside A: r2 = 0.51–0.71). The concentrations of both metabolites tend to decrease at leaf level during the ontogenetical development even under stress conditions. High-UV stress should be considered as a tool for enriching plant leaves with valuable SM. Effects on the performance of plants throughout a complete production cycle should be evaluated in future trials. All data is available online.

scholarly journals Reactive Materials in the Removal of Phosphorus Compounds from Wastewater—A Review

Materials ◽  
2020 ◽  
Vol 13 (15) ◽  
pp. 3377
Author(s):  
Sylwia Gubernat ◽  
Adam Masłoń ◽  
Joanna Czarnota ◽  
Piotr Koszelnik
Keyword(s):  
Sustainable Development ◽  
Green Chemistry ◽  
Sorption Capacity ◽  
Red Mud ◽  
Phosphorus Compounds ◽  
Reactive Materials ◽  
Static Conditions ◽  
Available Information ◽  
Potential Use ◽  
Modern Technologies

Modern technologies designed to treat wastewater containing phosphorus compounds are based on the processes of adsorption and precipitation. In addition, more environmentally friendly and cheaper materials are being sought to ensure greater conformity with overarching assumptions of green chemistry and sustainable development. Against that background, this paper offers a review and analysis of available information on the considered reactive materials that have the capacity to remove phosphorus from wastewater. These materials are categorised as natural (with a sub-division in line with the dominant sorption groups of Al/Fe or Ca/Mg), waste, or man-made. Notably, most studies on sorbents have been carried out in laboratory systems via experimentation under static conditions. Among the natural materials, opoka has the highest sorption capacity of 181.20 g P/kg, while red mud (in the waste material category) is most efficient at binding phosphorus with a level of 345.02 g P/kg. Finally, among the group of commercial materials, Rockfos® has the highest sorption capacity of 256.40 g P/kg. In addition, this paper recognises the effect of composition, pH, and physical properties on a reactive material’s capacity to absorb phosphorus, as well as the possibility for further potential use in the production of fertilisers.

scholarly journals Chronic cardiotoxicity of anticancer anthracyclines in the rat: role of secondary metabolites and reduced toxicity by a novel anthracycline with impaired metabolite formation and reactivity

2003 ◽  
Vol 139 (3) ◽  
pp. 641-651 ◽  
Author(s):  
Giuseppe Sacco ◽  
Rossella Giampietro ◽  
Emanuela Salvatorelli ◽  
Pierantonio Menna ◽  
Nicoletta Bertani ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Metabolite Formation ◽  
Reduced Toxicity

scholarly journals Volatile organic metabolites and their importance in Senecio L. (Senecioneae: Asteraceae)

2016 ◽  
Vol 10 ◽  
pp. 12-18 ◽  
Author(s):  
Sudha Joshi Shrestha
Keyword(s):  
Secondary Metabolites ◽  
Plant Science ◽  
Nepal Himalaya ◽  
Propenoic Acid ◽  
Dichotomous Key ◽  
Volatile Organic ◽  
Ethanolic Extracts ◽  
Taxonomic Marker ◽  
Potential Use ◽  
Level Analysis

The present work aims to characterize volatile secondary metabolites in Senecio L. for delimiting taxa at the infrageneric level. Analysis of n-hexane fraction of ethanolic extracts of five species of Senecio L. (S. laetus Edgew., S. nudicaulis Buch.-Ham. ex D. Don, S. raphanifolius Wall. ex DC., S. royleanus DC. and S. scandens Buch.-Ham. ex D. Don) from Nepal Himalaya revealed the presence of a number of volatile secondary metabolites. Among them, 17 metabolites, viz., acorenol, bergamotene, cadin, cadinene, calarene, caryophyllene, cumialdehyde, cycloprop(e)azulene, elemol, farnesene, hexanol, intermedeol, muurolene, naphthalene, naphthalenone, propenoic acid and tridecane were considered for their potential use in chemotaxonomy of the genus. All species were characterized by the presence of cadin, elemol, farnesene, muurolene, naphthalenone and propenoic acid and absence of acorenol, cycloprop(e)azulene, hexanol and intermedeol. Cumialdehyde is present in all species except S. royleanus; cadinene is present in all tested species except S. nudicaulis and S. royleanus. Moreover, S. nudicaulis can be delimited from other species by the presence of bergamotene; S. royleanus can be delimited from other species by the presence of tridecane and caralene. Caryophyllene is present in S. raphanifolius and S. scandens and absent in S. laetus. Naphthalene is present in S. nudicaulis, S. royleanus and S. scandens, and absent in S. laetus and S. raphanifolius. Presence and absence of a single metabolite or a group of volatile organic metabolites indicates its significance as the taxonomic marker for delimiting taxa at infrageneric level. An artificial dichotomous key is prepared to delimit the taxa.Botanica Orientalis – Journal of Plant Science (2016) 10: 12–18

scholarly journals Ecological conditions affecting mycotoxin production in cereals: a review

2013 ◽  
Vol 58 (No. 8) ◽  
pp. 405-411 ◽  
Author(s):  
JM Milani
Keyword(s):  
Secondary Metabolites ◽  
Water Availability ◽  
Raw Materials ◽  
Mycotoxin Production ◽  
Ecological Conditions ◽  
Post Harvest ◽  
Critical Control Points ◽  
Wide Range ◽  
Available Information ◽  
The Impact

Spoilage fungi are ubiquitous contaminants of cereals, pre- and post-harvest. These fungi can produce a wide range of secondary metabolites under ecological conditions which are conducive for growth. However, some of these secondary metabolites are toxic and have a significant impact if they enter the production and animal food chains. Prevention of mycotoxin contamination of feed and food raw materials is now considered more important than subsequent cure. The key ecological determinants pre- and post-harvest are water availability and temperature (climate). Accurate information is therefore needed on the impact of an association between these key factors, and it is necessary to understand which are marginal and which critical for germination and toxin production. There have only been a few studies where attempts have been made to integrate the available information on these factors in relation to different raw materials for feed and food processing, especially cereals. This review will examine the available information on the main climatic factors, i.e., water availability and temperature affecting mycotoxin production such as, aflatoxins, ochratoxins, fumonisins, zearalenone, deoxynivalenol and citrinin. This information is crucial for accurately focusing and monitoring key critical control points in the feed and food chain to optimise prevention strategies.  

Lichen Allelopathy: An Agricultural Prospect

2020 ◽  
Vol 6 (01) ◽  
pp. 01-08
Author(s):  
Rajesh Bajpai ◽  
D. K. Upreti
Keyword(s):  
Secondary Metabolites ◽  
Biological Invasion ◽  
Weed Control ◽  
Growth Regulators ◽  
Crop Protection ◽  
Negative Effects ◽  
Soil Sickness ◽  
Positive Effects ◽  
Near Future ◽  
Harmful Effects

Allelopathy is a common biological miracle by which one organism produces biochemicals that affect the growth, existence, development, and reproduction of other organisms. These biochemicals are known as allelochemicals and have advantageous, as well as, harmful effects on target organisms. Lichens produce over a thousand different extracellular biochemical terms as secondary metabolites. The lichen secondary metabolites may show either positive effects, such as, in weed control, crop protection, or crop re-establishment or negative effects, e.g., autotoxicity, biological invasion, competition, deterioration, and eutrophic soil sickness. However, several lichen secondary metabolites can potentially be used as growth regulators, insecticidal, and antimicrobial since dated back. Here, we discuss the application of lichen allelopathy in various agricultural prospects in the near future.

scholarly journals Novel Exenatide Analogs with Peptidic Albumin Binding Domains: Potent Anti-Diabetic Agents with Extended Duration of Action

PLoS ONE ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. e87704 ◽  
Author(s):  
Odile E. Levy ◽  
Carolyn M. Jodka ◽  
Shijun Steven Ren ◽  
Lala Mamedova ◽  
Abhinandini Sharma ◽  
...  
Keyword(s):  
Albumin Binding ◽  
Duration Of Action ◽  
Binding Domains ◽  
Extended Duration

scholarly journals Unraveling the Association between Metabolic Changes in Inter-Genus and Intra-Genus Bacteria to Mitigate Clubroot Disease of Chinese Cabbage

Agronomy ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2424
Author(s):  
Lanfang Wei ◽  
Jun Yang ◽  
Waqar Ahmed ◽  
Xinying Xiong ◽  
Qi Liu ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Plant Growth ◽  
Chinese Cabbage ◽  
Negative Impact ◽  
Nucleotide Metabolism ◽  
Biocontrol Agents ◽  
Growth Promoter ◽  
Promising Alternative ◽  
Clubroot Disease ◽  
Pgp Traits

Clubroot disease caused by the obligate parasite Plasmodiophora brassicae is a serious threat to cabbage production worldwide. Current clubroot control primarily relies on a fungicide, but this has a negative impact on the environment and the use of a single biocontrol agent cannot efficiently control the disease. Thus, the combined application of different biocontrol agents has been proposed as a promising alternative. In this study, we used bacterial biocontrol agents as a co-culture (inter-genus and intra-genus) and mono-culture to mitigate the clubroot disease of Chinese cabbage. We evaluated their biocontrol effect and plant growth promoter (PGP) traits in in vitro and in vivo experiments. This study revealed that the inter-genus bacterial co-culture significantly suppresses the incidence of clubroot disease and enhances plant growth compared with intra-genus and mono-culture. In pairwise interaction, we observed that Bacillus cereus BT-23 promotes the growth of Lysobacter antibioticus 13-6 (inter-genus bacterial co-culture), whereas L. capsici ZST1-2 and L. antibioticus 13-6 (intra-genus microbial co-culture) are antagonists to each other. Furthermore, a total of 5575 metabolites, 732 differentially expressed metabolites (DEMs), and 510 unique metabolites were detected through the LC-MS/MS technique in the bacterial co-culture. The number of unique metabolites in inter-genus bacterial co-culture (393 metabolites) was significantly higher than in the intra-genus bacterial co-culture (117 metabolites). Further analysis of DEMs showed that the DEMs were mainly involved in four kinds of metabolism pathways, i.e., carbohydrate metabolism, amino metabolism, nucleotide metabolism, and metabolism of cofactors and vitamins. The contents of some secondary metabolites with biocontrol activity and plant growth-promoting functions were increased in inter-genus bacterial co-culture, indicating that inter-genus bacterial co-culture has a solid potential to suppress clubroot disease. We conclude that the inter-genus bacterial interaction changes the community metabolism and improves several secondary metabolites functions with respect to disease control and PGP ability.

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